LOCUS       NM_181821               1256 bp    mRNA    linear   ROD 07-MAY-2024
DEFINITION  Mus musculus host cell factor C1 regulator 1 (XPO1-dependent)
            (Hcfc1r1), transcript variant 1, mRNA.
ACCESSION   NM_181821
VERSION     NM_181821.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1256)
  AUTHORS   Zhang,X., He,H., Yu,H., Teng,X., Wang,Z., Li,C., Li,J., Yang,H.,
            Shen,J., Wu,T., Zhang,F., Zhang,Y. and Wu,Q.
  TITLE     Maternal RNA transcription in Dlk1-Dio3 domain is critical for
            proper development of the mouse placental vasculature
  JOURNAL   Commun Biol 7 (1), 363 (2024)
   PUBMED   38521877
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1256)
  AUTHORS   Mahajan,S.S., Little,M.M., Vazquez,R. and Wilson,A.C.
  TITLE     Interaction of HCF-1 with a cellular nuclear export factor
  JOURNAL   J Biol Chem 277 (46), 44292-44299 (2002)
   PUBMED   12235138
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC154766.2.
            
            On Nov 23, 2022 this sequence version replaced NM_181821.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK013438.1, SRR13422590.453025.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-473               AC154766.2         19052-19524         c
            474-614             AC154766.2         18445-18585         c
            615-1256            AC154766.2         17595-18236         c
FEATURES             Location/Qualifiers
     source          1..1256
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 11.98 cM"
     gene            1..1256
                     /gene="Hcfc1r1"
                     /gene_synonym="HPIP"
                     /note="host cell factor C1 regulator 1 (XPO1-dependent)"
                     /db_xref="GeneID:353502"
                     /db_xref="MGI:MGI:2663619"
     exon            1..473
                     /gene="Hcfc1r1"
                     /gene_synonym="HPIP"
                     /inference="alignment:Splign:2.1.0"
     CDS             388..750
                     /gene="Hcfc1r1"
                     /gene_synonym="HPIP"
                     /note="isoform 1 is encoded by transcript variant 1; HCF-1
                     beta-propeller-interacting protein"
                     /codon_start=1
                     /product="host cell factor C1 regulator 1 isoform 1"
                     /protein_id="NP_861542.1"
                     /db_xref="CCDS:CCDS28455.1"
                     /db_xref="GeneID:353502"
                     /db_xref="MGI:MGI:2663619"
                     /translation="MILQQPLERGPPSRDPRATTGVTRGLNASLSPREPLHKQFLSEE
                     NMATHFSRLSLHNDHPYCSPPVTFPEALPPLRSPCPELLLWRYPGSLIPEALRLLRLG
                     DTPSPYYPASPAGDIVEL"
     exon            474..614
                     /gene="Hcfc1r1"
                     /gene_synonym="HPIP"
                     /inference="alignment:Splign:2.1.0"
     exon            615..1256
                     /gene="Hcfc1r1"
                     /gene_synonym="HPIP"
                     /inference="alignment:Splign:2.1.0"
     regulatory      935..940
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hcfc1r1"
                     /gene_synonym="HPIP"
                     /note="hexamer: AATAAA"
     polyA_site      958
                     /gene="Hcfc1r1"
                     /gene_synonym="HPIP"
                     /note="major polyA site"
     regulatory      1234..1239
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Hcfc1r1"
                     /gene_synonym="HPIP"
                     /note="hexamer: AATAAA"
     polyA_site      1256
                     /gene="Hcfc1r1"
                     /gene_synonym="HPIP"
ORIGIN      
        1 ctctcgacgc acgacacaac ctctcgattc cggacgtgcc tgatggtggc tcttctcgtt
       61 acgccccaag acctagcact gcctgtcgcc cagcaactaa ggcggcaggt ccgtgctgtc
      121 tcgaaccaca gaaacctagg agaactacac gaagcaccct tatgctaaaa agcgcccaga
      181 actatccagc cacgccggat cccctccccc accgcgccga cctgtcccgc cttctaacct
      241 ctaacctgat tcctgtcttc cgcgcctgcg taaaacgtct ccagtgcgca cgccggtagg
      301 cccgcccctc gcgctgtacc acgccctcaa aggctccgcc tctgctgctt gaatcccacc
      361 cctctatctg caggaccctg agccgtaatg atcctgcaac agcccctgga gcgaggtccc
      421 ccaagtcggg acccacgggc caccactggg gtaactcgcg gcctaaacgc cagtctttcc
      481 cccagggaac ctttgcacaa gcagttcctg tctgaggaga acatggccac ccatttctcc
      541 cgactcagcc tacataatga ccacccctac tgcagccccc ctgtgacttt tcccgaagcc
      601 ctgccaccac tcaggagccc ttgcccagag ctgcttctct ggcgctatcc cgggagcctg
      661 attcctgaag ccctcaggct gctgaggctg ggggataccc ccagtcccta ctaccctgcg
      721 tccccagctg gggatatcgt ggagctctga gtattgatgg cctgtgtccc tccctatctt
      781 ctttctgaca acaaagacca gcaactccca gaaagggatg aagtccttct gcaaacctgg
      841 ccaccaggac cttccctctg acaagaggac actagctcgg tggaaccctc agtgaaaggc
      901 agcctgggaa agggaaaatg ttaccccatt agtgaataaa gacctgtgag cagttgaaga
      961 tttctcagca gcctttgggg agggtggggt actggatgct ggggtttcct cctcaaaatc
     1021 ttccctggaa aatcggtgag ggcaagccag gtcctggcag gctgagctcc aggcattgag
     1081 aatgtgtgag tcacagcctc acccccgccc ccgcagtggc cgactggctc cctccctcca
     1141 gttctgggga gtcaagttag ggatcaggcc atatcttaaa gttaaagatt cttttattaa
     1201 taagtctccc tcccctccaa acattatccc cacaataaat atcacccccc ttggga
//
