LOCUS       NM_001033981             748 bp    mRNA    linear   ROD 06-MAR-2024
DEFINITION  Mus musculus hemoglobin, theta 1B (Hbq1b), mRNA.
ACCESSION   NM_001033981 XM_618856
VERSION     NM_001033981.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 748)
  AUTHORS   Storz,J.F., Hoffmann,F.G., Opazo,J.C. and Moriyama,H.
  TITLE     Adaptive functional divergence among triplicated alpha-globin genes
            in rodents
  JOURNAL   Genetics 178 (3), 1623-1638 (2008)
   PUBMED   18245844
REFERENCE   2  (bases 1 to 748)
  AUTHORS   Anguita,E., Hughes,J., Heyworth,C., Blobel,G.A., Wood,W.G. and
            Higgs,D.R.
  TITLE     Globin gene activation during haemopoiesis is driven by protein
            complexes nucleated by GATA-1 and GATA-2
  JOURNAL   EMBO J 23 (14), 2841-2852 (2004)
   PUBMED   15215894
REFERENCE   3  (bases 1 to 748)
  AUTHORS   Flint,J., Tufarelli,C., Peden,J., Clark,K., Daniels,R.J.,
            Hardison,R., Miller,W., Philipsen,S., Tan-Un,K.C., McMorrow,T.,
            Frampton,J., Alter,B.P., Frischauf,A.M. and Higgs,D.R.
  TITLE     Comparative genome analysis delimits a chromosomal domain and
            identifies key regulatory elements in the alpha globin cluster
  JOURNAL   Hum Mol Genet 10 (4), 371-382 (2001)
   PUBMED   11157800
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AL662780.20.
            
            On May 2, 2007 this sequence version replaced NM_001033981.2.
            
            Summary: This gene is one of two mouse theta-globin genes found in
            the alpha-globin gene cluster on chromosome 11. This gene
            represents the T1 (or 5') theta-globin gene described in PMIDs
            18245844 and 11157800, respectively. [provided by RefSeq, Apr
            2009].
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK157060.1, BC141224.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849381
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-144               AL662780.20        28730-28873
            145-349             AL662780.20        28969-29173
            350-748             AL662780.20        29280-29678
FEATURES             Location/Qualifiers
     source          1..748
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 18.86 cM"
     gene            1..748
                     /gene="Hbq1b"
                     /gene_synonym="F830116E18Rik; Hbqt1"
                     /note="hemoglobin, theta 1B"
                     /db_xref="GeneID:544763"
                     /db_xref="MGI:MGI:3613460"
     exon            1..144
                     /gene="Hbq1b"
                     /gene_synonym="F830116E18Rik; Hbqt1"
                     /inference="alignment:Splign:2.1.0"
     CDS             50..478
                     /gene="Hbq1b"
                     /gene_synonym="F830116E18Rik; Hbqt1"
                     /note="Hbq1 5'-theta"
                     /codon_start=1
                     /product="hemoglobin subunit theta-1"
                     /protein_id="NP_001029153.1"
                     /db_xref="CCDS:CCDS24524.1"
                     /db_xref="GeneID:544763"
                     /db_xref="MGI:MGI:3613460"
                     /translation="MARSQDDQWLVLALWKKMGSNVGIYATEALERTFVAFPSTKTYF
                     PHLDLRPGSSQVKAHAQKVADALTLATQHLDDLPASLSALSDLHAHKLCVDPANFQFF
                     SHCLLVTLARHYPGDFSPEMHASLDKFLGHVTSALVSKYR"
     exon            145..349
                     /gene="Hbq1b"
                     /gene_synonym="F830116E18Rik; Hbqt1"
                     /inference="alignment:Splign:2.1.0"
     exon            350..748
                     /gene="Hbq1b"
                     /gene_synonym="F830116E18Rik; Hbqt1"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtctttgagc tcagccagcg ggcagagcgc aaggctcagt tcactgaaga tggctcggtc
       61 ccaggatgat cagtggctgg tccttgcgct ctggaagaag atgggcagca atgtcggaat
      121 ctacgcgacc gaggctttgg agaggacctt cgtggctttc ccctccacca aaacctactt
      181 cccacacttg gacctgaggc caggctctag ccaggttaaa gcccatgccc aaaaggtggc
      241 cgatgcactg actctcgcta cccagcacct ggacgacctg cctgcttctc tgtctgctct
      301 cagtgatcta catgcgcaca agctctgtgt ggaccctgct aacttccagt tcttcagcca
      361 ctgtctgctg gtgactctcg ccaggcacta tcctggagac ttcagcccag agatgcatgc
      421 ctccttggac aagtttctgg gtcacgtgac ttcggcactg gtctccaaat atcgctgaat
      481 tggggataca gggttctata gtctccaccc atgcccttcc taaagctcac aatgtttgag
      541 taaacctccc cagggctgca ttgttgtcct ggacgcagag gggcacgaga gaaatatact
      601 ccccgcgtcc agtactccta aacaaggttc caagagactg aaagtacaga taagctggtg
      661 tctcagatct catatgggag gcagccatcc cttgtttgta ttgttttatt gtgtttttgc
      721 ctttgagata aatttcatgt tctcatgt
//
