LOCUS       NM_001163042            1686 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus 4HAUS augmin-like complex, subunit 8 (Haus8),
            transcript variant 1, mRNA.
ACCESSION   NM_001163042
VERSION     NM_001163042.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1686)
  AUTHORS   Kole,C., Berdugo,N., Da Silva,C., Ait-Ali,N., Millet-Puel,G.,
            Pagan,D., Blond,F., Poidevin,L., Ripp,R., Fontaine,V., Wincker,P.,
            Zack,D.J., Sahel,J.A., Poch,O. and Leveillard,T.
  TITLE     Identification of an Alternative Splicing Product of the Otx2 Gene
            Expressed in the Neural Retina and Retinal Pigmented Epithelial
            Cells
  JOURNAL   PLoS One 11 (3), e0150758 (2016)
   PUBMED   26985665
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1686)
  AUTHORS   Evsikov,A.V., Graber,J.H., Brockman,J.M., Hampl,A., Holbrook,A.E.,
            Singh,P., Eppig,J.J., Solter,D. and Knowles,B.B.
  TITLE     Cracking the egg: molecular dynamics and evolutionary aspects of
            the transition from the fully grown oocyte to embryo
  JOURNAL   Genes Dev 20 (19), 2713-2727 (2006)
   PUBMED   17015433
REFERENCE   3  (bases 1 to 1686)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CX220280.1, DV651534.1, BQ177845.1 and AI837612.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC003935.1, SRR5189685.124076.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164143
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-93                CX220280.1         344-436
            94-834              DV651534.1         1-741
            835-1379            BQ177845.1         249-793
            1380-1686           AI837612.1         1-307               c
FEATURES             Location/Qualifiers
     source          1..1686
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 34.43 cM"
     gene            1..1686
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /note="4HAUS augmin-like complex, subunit 8"
                     /db_xref="GeneID:76478"
                     /db_xref="MGI:MGI:1923728"
     exon            1..307
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /inference="alignment:Splign:2.1.0"
     CDS             279..1400
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /note="isoform 1 is encoded by transcript variant 1; HAUS
                     augmin-like complex subunit 8; sarcoma antigen NY-SAR-48
                     homolog; HEC1/NDC80-interacting centrosome-associated
                     protein 1; HEC1/NDC80 interacting, centrosome associated
                     1"
                     /codon_start=1
                     /product="HAUS augmin-like complex subunit 8 isoform 1"
                     /protein_id="NP_001156514.1"
                     /db_xref="CCDS:CCDS52579.1"
                     /db_xref="GeneID:76478"
                     /db_xref="MGI:MGI:1923728"
                     /translation="MADSSERDAGKSAAAGACAVPKTKGRRVQGRRVVESRYLQYDKK
                     AKKVSGAAKEEKPPEGRKASTVPRSREESQVMGTGNLQSTMLEGHGMNPPDLDLSAID
                     DKILSRKASWPDREMTDKAKSTSFISCDKKRILRKKRRDLQETMDMMESQTLLMTLLS
                     VKMENNLALLEERAEKDLAAMCHEKERLQRQALELRRQLLLRQKHQELAATLDAQIEV
                     LSPLQPVLERFKEEYMTLGRALDTTRHELPMQAVHMEGSGQELLDDLEPALRITLQLL
                     GDLSICSPYATAQVQGASAQEPGASTQLSCLLKELKGLVTEKDLELRRLVSQVVELSS
                     QASKEAALMNQEVWEEAEGALTSSQWYFSPDACRDDSPS"
     exon            308..366
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /inference="alignment:Splign:2.1.0"
     exon            367..419
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /inference="alignment:Splign:2.1.0"
     exon            420..489
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /inference="alignment:Splign:2.1.0"
     exon            490..585
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /inference="alignment:Splign:2.1.0"
     exon            586..698
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /inference="alignment:Splign:2.1.0"
     exon            699..764
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /inference="alignment:Splign:2.1.0"
     exon            765..923
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /inference="alignment:Splign:2.1.0"
     exon            924..1065
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /inference="alignment:Splign:2.1.0"
     exon            1066..1249
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /inference="alignment:Splign:2.1.0"
     exon            1250..1670
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1652..1657
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /note="hexamer: AGTAAA"
     polyA_site      1670
                     /gene="Haus8"
                     /gene_synonym="2410004L22Rik; Hice1"
                     /note="major polyA site"
ORIGIN      
        1 gtgttccaca gctgagaggg gcgggcgcta tgatagtcac gcccctcccc agcagtattt
       61 tagcccgctc aggttggtgc cggaagccca cacgtctgag ggacaccttg gagccacgcc
      121 ctttttcggc gctcttggcc aggctgaacg aactgtagca agcttggagc ccgccccgcg
      181 gctcgcgtga agagagcacc ctccggcttc cagcactact ccctgcctcc tagcgggcgg
      241 gaccctgaga cgcttgcctt tgagtggaag gcgggagaat ggcggattcc tcagaacggg
      301 acgcagggaa gtctgcagct gctggtgctt gtgctgttcc caagacaaag ggaaggagag
      361 tgcaaggaag aagagtggtg gagtcccggt atctgcaata tgacaagaaa gcaaaaaagg
      421 tttctggagc ggccaaagaa gagaagccac ctgagggaag gaaagccagc acagtgccta
      481 ggagcagaga agagagccaa gtgatgggga caggcaacct gcagtctacc atgctagaag
      541 ggcatggcat gaatccacca gacctagacc tctctgccat cgacgacaaa atcttgtcca
      601 ggaaggcttc ttggccagac agggaaatga cagacaaagc taagtccaca tcttttatca
      661 gctgtgacaa aaaaagaatc cttcggaaga aaagacggga tctgcaggag accatggaca
      721 tgatggagtc acagacactg ctgatgaccc tgctgtctgt gaagatggag aacaacctgg
      781 ctctgctgga ggagagggca gagaaagact tggcagccat gtgccatgag aaagagaggt
      841 tgcagaggca ggcactggag cttcggcgcc agctgcttct ccggcagaaa catcaggagc
      901 tggccgccac ccttgatgcc cagattgagg tgctgagtcc tcttcagcct gtgttagagc
      961 gcttcaaaga ggaatacatg acactgggca gagccctgga caccacgcga cacgagctgc
     1021 ccatgcaggc tgtccacatg gaaggaagtg ggcaggagct cctagatgat ctggagccag
     1081 ccctgaggat caccctgcag ctcctgggtg atctgagcat ctgctcccca tatgccactg
     1141 cacaggtgca gggtgccagc gcacaggagc ctggagccag cacacagctg agttgtctgc
     1201 tgaaggaact gaagggcttg gtcactgaga aagacctgga gctccgcaga cttgtcagcc
     1261 aggtggtaga actttcctcc caggccagta aagaagcagc tttgatgaac caggaagtct
     1321 gggaagaggc agagggtgcc ctcaccagca gccagtggta cttcagtcca gatgcctgca
     1381 gggatgatag tccctcttag gacaggatga attacagcag gcctgaccct tgattgcctc
     1441 aggcagcctg tcctacctga gtatttccta gctggccttt ctgctcattt atgtttcctc
     1501 atgcctcctc cttgtggacc gaaggaagtt tggtggtcca gtattctgaa agcttgtgca
     1561 ctttggtttt ggtttgcttt ggtttttgtc ttgaggtggg aagaaacacc agtcttggcc
     1621 acaccatctg ctgggtttgg gttctaaact gagtaaagaa agcaagctga aaaaaaaaaa
     1681 aaaaaa
//
