LOCUS       NM_028633               1365 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus HAUS augmin-like complex, subunit 7 (Haus7),
            transcript variant 1, mRNA.
ACCESSION   NM_028633 XM_972979
VERSION     NM_028633.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1365)
  AUTHORS   Wang,Y.P., Qi,S.T., Wei,Y., Ge,Z.J., Chen,L., Hou,Y., Ouyang,Y.C.,
            Schatten,H., Zhao,J.G. and Sun,Q.Y.
  TITLE     Knockdown of UCHL5IP causes abnormalities in gamma-tubulin
            localisation, spindle organisation and chromosome alignment in
            mouse oocyte meiotic maturation
  JOURNAL   Reprod Fertil Dev 25 (3), 495-502 (2013)
   PUBMED   23182369
  REMARK    GeneRIF: Data suggest Uchl5ip has role in spindle formation in
            oocyte meiotic maturation; Uchl5ip protein level is consistent
            during metaphase I/II; Uchl5ip localizes to meiotic spindle; loss
            of Uchl5ip disrupts localization of gamma-tubulin to spindle poles.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL732461.23.
            
            On Aug 16, 2007 this sequence version replaced NM_028633.2.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY029337.1, BC025464.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-195               AL732461.23        189478-189672       c
            196-311             AL732461.23        188617-188732       c
            312-379             AL732461.23        185510-185577       c
            380-441             AL732461.23        183642-183703       c
            442-533             AL732461.23        179454-179545       c
            534-692             AL732461.23        178835-178993       c
            693-789             AL732461.23        178603-178699       c
            790-999             AL732461.23        177571-177780       c
            1000-1114           AL732461.23        176453-176567       c
            1115-1365           AL732461.23        167958-168208       c
FEATURES             Location/Qualifiers
     source          1..1365
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 37.32 cM"
     gene            1..1365
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /note="HAUS augmin-like complex, subunit 7"
                     /db_xref="GeneID:73738"
                     /db_xref="MGI:MGI:1920988"
     exon            1..195
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /inference="alignment:Splign:2.1.0"
     CDS             91..1185
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /note="isoform 1 is encoded by transcript variant 1;
                     UCHL5-interacting protein; 26S proteasome-associated
                     UCH37-interacting protein 1"
                     /codon_start=1
                     /product="HAUS augmin-like complex subunit 7 isoform 1"
                     /protein_id="NP_082909.1"
                     /db_xref="CCDS:CCDS30202.1"
                     /db_xref="GeneID:73738"
                     /db_xref="MGI:MGI:1920988"
                     /translation="MAEEGAGAGSDDSYYKDVGDDCVVKAAVEVFEKLKGVNCPFLDG
                     LYITEPKTIMELLCRPSKYRLDILEWMCIRVCPSLQDKFISLKGNALDLKIQEMLKLG
                     HELMFCAPDDQDLLMGRECPQKQLQFMDKILDMMQSLATGCSSSSSLKEHLEDTTEKN
                     EALLGELFSSPNLRAILKPESDPWPLDMQSSLNKQSDDLPKADPSAQSEGEKVADLAR
                     QLQESATKLQTLRDQCFAQHKAGTDTSTIDQKLRLVISDFYQLILAFLQVYDDELREC
                     CQRPVPSLHPSGPIIQAVYQTLASCGQLLRAVMEIADTSAEAMKAARKQEGEPNCWSS
                     NNSGISLAARIDEVTQKYKILTDRFHRGTR"
     exon            196..311
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /inference="alignment:Splign:2.1.0"
     exon            312..379
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /inference="alignment:Splign:2.1.0"
     exon            380..441
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /inference="alignment:Splign:2.1.0"
     exon            442..533
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /inference="alignment:Splign:2.1.0"
     exon            534..692
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /inference="alignment:Splign:2.1.0"
     exon            693..789
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /inference="alignment:Splign:2.1.0"
     exon            790..999
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1000..1114
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /inference="alignment:Splign:2.1.0"
     exon            1115..1365
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1344..1349
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /note="hexamer: AATAAA"
     regulatory      1349..1354
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /note="hexamer: AAGAAA"
     polyA_site      1350
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /note="major polyA site"
     polyA_site      1365
                     /gene="Haus7"
                     /gene_synonym="1110020L19Rik; Uchl5ip; Uip1"
                     /note="major polyA site"
ORIGIN      
        1 gagacctaag aaactggtga gcttttagca gtgtggcggc ggcctgtaag cttggggggc
       61 gtgaaccagt tgtagttcag agcgcgaaac atggcggagg agggtgccgg tgccgggtct
      121 gatgacagct actacaaaga tgtgggtgat gactgcgtgg tcaaggcagc tgtagaggtg
      181 ttcgagaagc tgaagggtgt aaactgcccc ttcctcgacg gcctgtatat tacagaacca
      241 aagacaatta tggagctgct gtgtaggccc tcaaagtacc ggttggacat actggaatgg
      301 atgtgtatac gggtctgccc ctccttgcaa gacaagttca tctcactgaa agggaatgca
      361 ttggatttga agatacagga gatgttgaag ctaggccatg agctgatgtt ttgtgcacca
      421 gatgaccagg atcttctaat gggccgtgag tgtccccaga agcaactaca gttcatggac
      481 aagatactgg atatgatgca gagcctggcc actggatgct ccagtagttc tagcctgaag
      541 gaacaccttg aagacaccac agagaagaat gaggcgttgc ttggggaact cttctccagc
      601 cccaacctga gggcaatttt gaaacctgag agtgacccat ggcctctgga catgcagtcc
      661 tctctaaaca agcaatctga tgacctgcca aaggctgacc cctctgccca gtcagaggga
      721 gaaaaggtgg cagatctggc caggcagctg caggagagtg ctactaagct tcagacactc
      781 cgagaccagt gctttgcaca gcataaagca gggactgaca ccagcaccat agaccagaaa
      841 cttcgtctgg tcatctctga cttctaccag ctcatcttgg ccttcctgca agtctatgat
      901 gatgagctac gcgagtgctg tcagcgccca gtacccagcc tgcacccaag tggccccatc
      961 atccaagctg tctatcagac tctggcttcc tgtggccaat tgttgagagc agtcatggag
     1021 attgcagaca cctctgccga agctatgaaa gcagcaagga agcaggaagg agagccaaac
     1081 tgttggagca gcaacaactc tgggataagc ctagctgcca gaattgatga agtaacacag
     1141 aagtacaaga tccttactga cagatttcac agaggcacaa gatgatgcag ggctataaag
     1201 ccctccctgg agctttcagg agggccagtt ccaatcctga tcacagcctg catggatttc
     1261 cacttgcctg gtgcttgcag tttgaaggga aggaggaaga gggaggcaga aaaggaaggc
     1321 agagatgggt aggagaggga agaaataaaa gaaactcaag cttaa
//
