LOCUS       NM_173400               6173 bp    mRNA    linear   ROD 12-SEP-2023
DEFINITION  Mus musculus HAUS augmin-like complex, subunit 6 (Haus6), mRNA.
ACCESSION   NM_173400
VERSION     NM_173400.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6173)
  AUTHORS   Schweizer N, Haren L, Dutto I, Viais R, Lacasa C, Merdes A and
            Luders J.
  TITLE     Sub-centrosomal mapping identifies augmin-gammaTuRC as part of a
            centriole-stabilizing scaffold
  JOURNAL   Nat Commun 12 (1), 6042 (2021)
   PUBMED   34654813
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 6173)
  AUTHORS   Viais R, Farina-Mosquera M, Villamor-Paya M, Watanabe S, Palenzuela
            L, Lacasa C and Luders J.
  TITLE     Augmin deficiency in neural stem cells causes p53-dependent
            apoptosis and aborts brain development
  JOURNAL   Elife 10, e67989 (2021)
   PUBMED   34427181
  REMARK    GeneRIF: Augmin deficiency in neural stem cells causes
            p53-dependent apoptosis and aborts brain development.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6173)
  AUTHORS   Bedogni F and Hevner RF.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 6173)
  AUTHORS   Watanabe S, Shioi G, Furuta Y and Goshima G.
  TITLE     Intra-spindle Microtubule Assembly Regulates Clustering of
            Microtubule-Organizing Centers during Early Mouse Development
  JOURNAL   Cell Rep 15 (1), 54-60 (2016)
   PUBMED   27052165
  REMARK    GeneRIF: Augmin is essential for embryonic cell division.
            Microtubule-organizing center clustering during the blastocyst
            stage requires augmin.
REFERENCE   5  (bases 1 to 6173)
  AUTHORS   Tamplin OJ, Kinzel D, Cox BJ, Bell CE, Rossant J and Lickert H.
  TITLE     Microarray analysis of Foxa2 mutant mouse embryos reveals novel
            gene expression and inductive roles for the gastrula organizer and
            its derivatives
  JOURNAL   BMC Genomics 9, 511 (2008)
   PUBMED   18973680
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6173)
  AUTHORS   Okazaki N, F-Kikuno R, Ohara R, Inamoto S, Koseki H, Hiraoka S,
            Saga Y, Seino S, Nishimura M, Kaisho T, Hoshino K, Kitamura H,
            Nagase T, Ohara O and Koga H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: IV. The complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 11 (3), 205-218 (2004)
   PUBMED   15368895
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB851382.1, BC068237.1, BY471626.1, AL824707.7 and BX516644.1.
            
            On Sep 29, 2017 this sequence version replaced NM_173400.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC068237.1, AK077681.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                BB851382.1         3-35
            34-3729             BC068237.1         1-3696
            3730-3974           BY471626.1         264-508
            3975-5814           AL824707.7         129134-130973       c
            5815-6173           BX516644.1         24-382
FEATURES             Location/Qualifiers
     source          1..6173
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="4"
                     /map="4 40.69 cM"
     gene            1..6173
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /note="HAUS augmin-like complex, subunit 6"
                     /db_xref="GeneID:230376"
                     /db_xref="MGI:MGI:1923389"
     exon            1..370
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     CDS             243..3044
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /note="likely ortholog of H. sapiens family with sequence
                     similarity 29, member A (FAM29A)"
                     /codon_start=1
                     /product="HAUS augmin-like complex subunit 6"
                     /protein_id="NP_775576.2"
                     /db_xref="CCDS:CCDS18307.1"
                     /db_xref="GeneID:230376"
                     /db_xref="MGI:MGI:1923389"
                     /translation="MSSARDSAFEKQHLWMYLQALGLDPSSSITFGGKMVPHAHLGEN
                     MFDKLNRDAFHIVSYFLFKTLDEALAKEVFRDCWPPFDQKLDMEFRKHCCEWLKEISA
                     ECGSSFPQVVGSLLMSPGGPKFIHLMYHFARYVAIKYIKTKSNNSLHFAETFNVKPQD
                     MHKCLARSHVARNRFLQILQREHYVMQKYQENVNLSVKQVRNARSECMSLQNQIKRME
                     PYDEKSNTQEKIQKVRSLWASVNETLMVVEKERDVISSLFGFVNQYALDGAHVAVNIP
                     RLLLDRLEEQICRLQIGNVYEAGKLNLLTIIHLLNEVLKIMKYEHCKAGQAGLTINLH
                     YLEKETKFQRERLSHMKHMRHKVKETVTAVRQSIADKEGKWHMKWKGFLGLSPFRLIK
                     DRPAAVDLLPPMSPLTFDPVSEEVYAKSILFKYPASLPDSHKEPKQESGSRREVDTPG
                     SVCDGANSPVPFPLQCAASSDTNSSTLLEKDPNMRTPIEKTLTYKTIADSEEEDSPLS
                     DTAKNSQSSVSRGTLPVKRSEPFQKEQARLVDEVARVVLSDSPQLSERKEVELEELID
                     TLISNPFLTRKQIPRTPENLITDIRSSWRKAVETEDNRSSDGILVDASAREVSSESSS
                     TLHNQREFSLAIFSPDFDRSYFPEEKAVSDQLKGLPQKHLVTSQIREPPTEDVSDLVN
                     KKMIWKQDLECATTRLSETSHMDVFSPVVGSGIDVMSRSKEDCVPVPPDHSQASCIEP
                     STHKTLLWDSFQRLSGIGILHETLPEVGRLSLNSSTSSETSFNLEPKSYVHSDAFADD
                     VGKGQAIPELDSNLQARLTSYEALKKSLSKIREESYLSNPKTLEQHKVELSPVAKAVQ
                     ADDAHTVWDTQDLFIDYAKPSSLVPLDGKTQTVSLTKAFLVEQKLKTTVPCSLGEFLP
                     SLKEEEISSKSLEARDSLI"
     exon            371..466
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            467..545
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            546..678
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            679..823
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            824..889
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            890..938
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            939..1109
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            1110..1303
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            1304..1430
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            1431..1533
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            1534..1615
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            1616..1682
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            1683..1865
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            1866..2001
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            2002..2994
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
     exon            2995..6158
                     /gene="Haus6"
                     /gene_synonym="6230416J20Rik; 9830144E06; D4Ertd27e;
                     mKIAA1574"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 ctgcgcagtg tagtcttccg caagcgcggg agtcttggtt tgcgtggagc gctgcagtca
       61 ctgtctgttt ttctgggcgc gttcggcctt ttgtggtggg atggctctcg gagaggaggc
      121 agcgggcggc cgccgcagag gggttgtcgt caccccggga tgcctgtagg aggggtccaa
      181 gggtcctcac ggcttcggtg ccttcgtttt cctccgtcac agtcgccctg cccgtggaaa
      241 gcatgagctc ggcccgggac tccgctttcg agaagcagca tctctggatg tacctgcagg
      301 cgctgggctt ggatccgagc tccagcatca cgttcggcgg gaagatggtg ccgcacgcgc
      361 accttggaga gaatatgttt gacaaactga accgtgatgc ctttcatata gtttcttatt
      421 ttttgtttaa aacattggat gaggctcttg ccaaagaagt tttcagagat tgctggcctc
      481 catttgacca aaaacttgac atggaattcc ggaaacattg ctgtgaatgg ttaaaagaga
      541 tttctgctga atgtgggagt agttttcctc aagttgttgg ctcattgctt atgtctcctg
      601 gtggccctaa gtttattcat ctgatgtatc attttgcaag atatgttgca atcaaatata
      661 ttaaaacaaa atctaacaat tctctacatt ttgcagaaac atttaatgta aagccacaag
      721 atatgcacaa gtgccttgcc agaagccatg tagcacgtaa cagattttta cagattttgc
      781 aaagagaaca ttatgttatg caaaaatacc aggaaaatgt aaatctgtct gttaagcaag
      841 tacgaaatgc aagatcagag tgcatgagtc tacagaacca aattaaaaga atggagccat
      901 atgatgagaa gagtaataca caagagaaga ttcaaaaggt tcggtccttg tgggcttcag
      961 tgaatgagac actcatggtt gtggaaaagg agagagacgt tattagttca ctctttggct
     1021 ttgtcaacca gtatgctttg gatggagctc atgttgctgt taatattcca aggctcttac
     1081 ttgacagact tgaggagcag atatgtcggt tgcagatagg aaatgtttat gaggctggaa
     1141 aattgaacct cttaacaatt attcacttgt taaatgaagt cttgaaaata atgaaatatg
     1201 aacattgtaa ggctggccaa gcaggattga caataaatct ccactacctt gaaaaagaaa
     1261 ccaaatttca gagggaaaga ttatcacata tgaagcatat gaggcataaa gtaaaagaga
     1321 ccgtcactgc agtgagacag tctattgctg acaaggaggg aaagtggcat atgaagtgga
     1381 aaggctttct tggcctgtct cctttcagac taattaaaga cagacctgca gctgtggatc
     1441 ttttgcctcc catgtctcct cttacgtttg atcctgtgtc agaggaagta tatgcaaaga
     1501 gtatactttt taagtatcct gcttcacttc cagattcaca taaagaacct aaacaagaaa
     1561 gtggtagcag aagagaagtg gataccccag gaagtgtgtg tgatggagct aacagccctg
     1621 tgccttttcc cttacagtgt gccgcgtcct cagatacaaa cagttccaca ctccttgaga
     1681 aggatccaaa tatgaggact cccatagaga aaaccttgac atataagaca atagcagact
     1741 ctgaagagga agactctcct ctatcagata ctgcaaagaa ttcacaaagt agtgtttcca
     1801 gagggactct gccggtgaag aggagtgagc cattccagaa agagcaagcc cgtctggtag
     1861 atgaggttgc cagagtagtt ctgtctgatt ccccacagct ctctgagaga aaagaagttg
     1921 aattggagga gctgattgac actttaattt ctaatccctt cttaaccagg aagcaaattc
     1981 cccggactcc agagaacttg ataactgata ttaggagctc atggagaaaa gctgttgaaa
     2041 ctgaagataa cagaagttca gatgggattc tagtggatgc cagtgctaga gaagtgtcgt
     2101 cagagtcttc atctacactg cataatcaga gggaatttag cctggctatt ttttccccag
     2161 attttgatcg gtcttatttt cctgaagaga aagctgtctc agatcagctt aaaggtttac
     2221 ctcagaaaca tctggtaaca agtcagatca gagaaccccc aacagaagat gtgtcagact
     2281 tggtaaataa gaaaatgatt tggaagcaag atttagaatg tgcaaccacc aggctttcag
     2341 aaactagtca catggatgta ttctcccctg ttgtgggcag tggaatagat gtgatgagta
     2401 gaagtaaaga ggactgtgtt ccagtaccgc cggaccactc acaagcttct tgcattgagc
     2461 cttccacaca taaaactctg ttatgggatt cttttcagag gttgagtggt attggtatat
     2521 tacatgaaac tcttccagaa gttggtcgcc taagtcttaa tagttctact agttcagaga
     2581 ctagttttaa tctggaacca aagagttatg tgcacagtga tgcttttgca gatgatgtgg
     2641 gaaaaggaca agctattcca gaattagatt ctaatttaca ggctcgtctc actagttatg
     2701 aggctctgaa gaaatctctt agcaaaatca gggaagaatc ttacctgtct aatcccaaga
     2761 cacttgaaca acacaaagta gaactgagcc ctgtagccaa agctgtgcaa gcagatgatg
     2821 cacacactgt ttgggacact caggatttgt ttattgacta cgcaaagcca tcttccctcg
     2881 tgccacttga tggaaaaaca cagactgtat cactaactaa agcttttctg gtggagcaaa
     2941 aattgaagac cacagtacca tgtagccttg gagaatttct gcctagttta aaagaagaag
     3001 aaatctcaag taagagcctt gaagcaagag actctctgat ttgacaagat gaagcatttt
     3061 caagttgatt tagctgtgat gcacttaccc tgaagtcttg tcactgaact gcagctgata
     3121 tcatacattg gaagtgaatt cttttgtcag catcaaagga gttcagaatg tacttggctt
     3181 cttataagtg tttaggtctt tttttttttt tttggtaaat gttatgagtt tgaaatatga
     3241 agtatttaag aacagaaaat gtcaaatttt agaaaacaat tttgattcct agaataatct
     3301 tataagtgaa tgacaaatat catagttatg ttaaaaatat ctgtcgttaa catgagttag
     3361 tgcctaacct aatggccact gaataactgc atctttcatt ttagagaaat aaaccatttt
     3421 attggatctt aatggaatat tctggtaata acacaaagtg tagtaccttt acctttggat
     3481 ggatatttag tcaaagcagc acaccttaga ttgtaagcag gcttaatgaa ttctaagtct
     3541 attggtcctg cagagtgatg ttgatgggat aaaatgcatg tggttggtga agaagattgg
     3601 agaaactgac gaaaatgggt aaatagagat gggcagacct ttaaagaaca ctgtcaaact
     3661 ctgtgtactt tagactgaga atttaattct atttatattt aacaagaata taaatgcaaa
     3721 atttacaaat ttgttttacc attgtggtct gtggatggta tgttgggggt gttttgggaa
     3781 aagcaacaag ttttttgtta cttactgatt ggaaacattc acgtttccta gtgcctacag
     3841 agtatcccaa aataatttga gaaaattgaa catggattta ggcaacttgt aacattcgta
     3901 tgtttttgcc tcattgtcag gggtcttgtt tgtattatct aaggaataaa tacatgtgcc
     3961 tgaataagcc tgactagaag aggcactaac ggttgattta ttatctcctc ctagtctgtg
     4021 aagagcctca gtgtgtaact atcaaaatct tgttcccaag ccttaagaaa atgagagaag
     4081 agaaaggtag atggcctgag ttgtcagaag gactgtctaa aagctgcttg acagagggac
     4141 ggaaagaagt catggtcccg agggctctgg gttccttcat gagtgcaaag aggacatggt
     4201 cccgagggct ctgggttcct ttatgagtgc agcagagcag ggactgctca ggtgtactgg
     4261 gaaatccttt gctgtcttct ttacagccta gtatctacat tctaaatagc atgttaagga
     4321 agaggaagga ctatcagggg agccagagca gggctaagtg ttcaatatgc atgattgcat
     4381 ttaacctttg taattgagat aggaggcata cctagcctgc agatacagaa gctaagagat
     4441 gaagtggctg gagtaggatg cagggaccaa ctgtattagg atcatctgag atgcctgttt
     4501 aaaaatgctc atttagagag gatctagaaa tctcatttca aatacgcttc catggcaact
     4561 cacaagttca gcagtttgct gccaagagga tgggattcat atttagtccc taggtaccgt
     4621 taagaagtgg cacactattg taagtatatt gctctaggag cccttcatta tgagagtcaa
     4681 aagatgaagt atctggctat tttgggttta taagtcacta aaatttacct atagtcggct
     4741 gagcatttct gaaatgatca tttcctgttt cagtaccatg aacaaatctc aactctcact
     4801 tctccaaaac tgattataac ttagtgtttc agtgccttcc tgcacagtag tgccttctcc
     4861 tgcagttagt tccctttgac gtttaggaac tactttgatc atgtcaggcc cttgcttaaa
     4921 agcccattga tggttcattg taattataga acagcgtttt ggtataaaga ccccttcttc
     4981 tctcctccca cctcctgctg ggatctttta ccttgtcctc ctagttcacc tcagttcttt
     5041 gttagtttgc agactctaat aacctttaat tataccagtt aggattaaaa aaaattattt
     5101 attttcacat gtaggatatt tttcttctaa tttttaattt attttcatgt gtgtggatgt
     5161 ttgccaacat gtctgtgtac ctctttggtg cctggtgctc cctgaggagg gagtcagatc
     5221 ctctgagact ggtgttagca tccacatagg tgctaggact tgatcctggg tcacaggatg
     5281 agcagccact ggggtatctc ttcagccagc tatagttcct ttaaaattca cagcagcact
     5341 ttaacccttt aaacaccttt gatctcagcc ttggggaggc aggcagatct gagtctagtc
     5401 tacagtcagt tccaggacag ccagtgcaac atagtgaggc cctgtctgca aagacaagac
     5461 tgaaggttca gacaaatgac attttctacc ttgatgtctt agtttgccct ccctagatcc
     5521 atggtcttcc atcttttctg aagtatatag tatagctgtt ttgtgtgtgg ggagggtgtg
     5581 gtggtgggga gacaggaatt ttgctgtttt tgttcaggtt agcttcagct tacagctgtc
     5641 ttctgcctca gtcttccaag tgctggaact acagatgttt gcctagcttt tccttaatgt
     5701 ctttgttaga catctccccc gactttatgt gatttctgat ccagctgtat acacaccttg
     5761 gtgctgagca tgaaaagtgg tactaagtaa gataaagaac atttgggggg ggggcaggga
     5821 ttaagcttaa caaaatacta aacagacatt ttgaaacctt tacaatattc ttagttataa
     5881 ggtatcatcc catttttttt ctagcgtgta aacaggaatt cttgagacct gtataaaagc
     5941 aaactatttc tccccctagt atactaaaaa atgtgtttca aaacatttca tttaatgtgt
     6001 gaagacagta tatatagatc agatgcctgg ttgctctaaa gagcacccac ctttttatgc
     6061 actgagagct ggcaagttca tgctgttaag tggaaaatgt ctgtgttcta aggactgttc
     6121 tacatactgc tgtctagaat aaacaatgtt tcaccactaa aaaaaaaaaa aaa
//
