LOCUS       NM_145462               1588 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus HAUS augmin-like complex, subunit 4 (Haus4), mRNA.
ACCESSION   NM_145462
VERSION     NM_145462.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1588)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB855694.1, AK079852.1 and AI642699.1.
            
            On Nov 26, 2009 this sequence version replaced NM_145462.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC011095.1, AK079852.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-33                BB855694.1         3-35
            34-1585             AK079852.1         2-1553
            1586-1588           AI642699.1         1-3                 c
FEATURES             Location/Qualifiers
     source          1..1588
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="14"
                     /map="14 27.83 cM"
     gene            1..1588
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /note="HAUS augmin-like complex, subunit 4"
                     /db_xref="GeneID:219072"
                     /db_xref="MGI:MGI:1261794"
     exon            1..187
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /inference="alignment:Splign:2.1.0"
     exon            188..261
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /inference="alignment:Splign:2.1.0"
     CDS             207..1298
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /codon_start=1
                     /product="HAUS augmin-like complex subunit 4"
                     /protein_id="NP_663437.2"
                     /db_xref="CCDS:CCDS27092.1"
                     /db_xref="GeneID:219072"
                     /db_xref="MGI:MGI:1261794"
                     /translation="MASGDFCAPGEGVEMLLQVCGKQFPPCALTEEDLIQNPRFSKLL
                     LSLSQHVDESGLSLTLAKEQAQAWSEVRHRKTAWLRYEILQRVIQELLVDYYVKAQDT
                     NLTSEDKKFHETLEQRLLVTELTQLSGPGQETELPPLLGLERTDLLELMPPSQDFVWM
                     KARLQLEVEEQLKRKCFTLLCYHDPSSDTDGDTLKAAKVWTLTEVLVREKQQCLEAKS
                     QQKEQLVLLEKKRTTYSQVLLRCLALLQRLLQEHRLQTKSELDRINAQYLELKCSAMI
                     LRLRMEELKVLSDTYSAEKVEMHRLIRDRLEGAIRLQEQDLEKSRLVLHTYEALGEDF
                     ESLVREYTQLRLAADNKRWALQELSKAQR"
     exon            262..404
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /inference="alignment:Splign:2.1.0"
     exon            405..536
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /inference="alignment:Splign:2.1.0"
     exon            537..671
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /inference="alignment:Splign:2.1.0"
     exon            672..768
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /inference="alignment:Splign:2.1.0"
     exon            769..914
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /inference="alignment:Splign:2.1.0"
     exon            915..1045
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /inference="alignment:Splign:2.1.0"
     exon            1046..1114
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /inference="alignment:Splign:2.1.0"
     exon            1115..1587
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1563..1568
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /note="hexamer: AATAAA"
     polyA_site      1587
                     /gene="Haus4"
                     /gene_synonym="9430093H08Rik; D14Ertd500e"
                     /note="major polyA site"
ORIGIN      
        1 gaggccccgc cccgtcctgt gcccggctga tttaagaccc agttgtttct acgctggcgg
       61 cagcgccttt cccgggcagg ccccggcctt agcgctccgg cggcgagccg tgcaggttag
      121 cgctcgacga ccgcgagctt gcggcgaggc cgcgctcgcc ctttaggact ccttggcgac
      181 ccagacgata ataccaagaa aacgagatgg cgtctggaga tttctgtgca cctggagaag
      241 gtgtagaaat gctgctgcaa gtgtgcggta agcagtttcc tccgtgtgcc ctgacggaag
      301 aggatctcat acagaatcca cgtttcagca agctgttgct cagtctctcc cagcacgtgg
      361 atgaaagtgg cttgagcctc acgctggcca aggagcaggc tcaggcgtgg agtgaagttc
      421 ggcatcgtaa gacagcatgg ctgaggtatg agatcttaca gagagttatc caagagctgc
      481 tcgtggacta ctatgtgaag gcccaagaca caaacctaac ctccgaagac aaaaagtttc
      541 atgagaccct tgaacagcgg ctgctcgtaa ctgagctgac gcagctctca ggtcccgggc
      601 aggagacaga gttgcccccg ctgctaggtc tggagaggac cgaccttctg gagctcatgc
      661 cgccctccca ggatttcgtg tggatgaaag cccggctcca gctggaggtg gaggagcagc
      721 tcaagaggaa atgcttcacg ctgctgtgct accatgaccc cagttcagat actgatggag
      781 acacactgaa agcagcgaag gtgtggacgc tgacagaggt cctggtcagg gagaagcagc
      841 agtgcctgga ggccaagagc cagcagaagg agcagctggt actcctggag aagaagagga
      901 ccacctactc ccaggtgctg cttcgctgcc tcgctttgct gcagaggctt cttcaggagc
      961 accggctgca gaccaagtcc gagctagacc gcatcaatgc ccagtacctg gagctgaagt
     1021 gcagtgctat gattcttagg ttgaggatgg aggagctgaa ggtcttgtct gacacttaca
     1081 gcgctgagaa agtggaaatg catcgcctca tcagggaccg tttggaggga gccatccgcc
     1141 tccaagagca ggacctggag aagtcaagac tagtcctgca cacctatgag gccctgggag
     1201 aagactttga gagcttggta agggagtaca cccagctcag actggcagcc gacaacaagc
     1261 gctgggccct ccaggagtta agcaaggccc agcgctgagc tgagtggagg cagaaccagg
     1321 aagcgtgaat tctccatggc caccttctct tcttgctcag tggaccacca ccaccaccac
     1381 aagggaatat ggggacactt gcttaaaacc ctgcaatctt cacaacaccc ttctgggttc
     1441 tctttcttgt ttacaatgac aacaagaaga gaccttctgg gtctcttctg gaaatgtagc
     1501 tatcagattt ataaaattcc gtacatatct gttttgcatc aggcgtgtgt aataatttcc
     1561 tgaataaagt tgtagtattg tgccttaa
//
