LOCUS       NM_025475               3170 bp    mRNA    linear   ROD 31-MAY-2024
DEFINITION  Mus musculus HAUS augmin-like complex, subunit 2 (Haus2),
            transcript variant 1, mRNA.
ACCESSION   NM_025475
VERSION     NM_025475.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3170)
  AUTHORS   Bouissou,A., Verollet,C., de Forges,H., Haren,L., Bellaiche,Y.,
            Perez,F., Merdes,A. and Raynaud-Messina,B.
  TITLE     gamma-Tubulin Ring Complexes and EB1 play antagonistic roles in
            microtubule dynamics and spindle positioning
  JOURNAL   EMBO J 33 (2), 114-128 (2014)
   PUBMED   24421324
REFERENCE   2  (bases 1 to 3170)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY711279.1, AK012779.1, BC086677.1, AL772299.10 and BP766698.1.
            
            On Mar 20, 2014 this sequence version replaced NM_025475.2.
            
            Transcript Variant: This variant (1) represents the longest
            transcript and encodes the longest isoform (a).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK132300.1, BC086677.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-16                BY711279.1         3-18
            17-62               AK012779.1         17-62
            63-1979             BC086677.1         1-1917
            1980-2624           AL772299.10        110343-110987
            2625-3170           BP766698.1         24-569              c
FEATURES             Location/Qualifiers
     source          1..3170
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 60.37 cM"
     gene            1..3170
                     /gene="Haus2"
                     /gene_synonym="1700101G24Rik; 2410007P03Rik; Cep27"
                     /note="HAUS augmin-like complex, subunit 2"
                     /db_xref="GeneID:66296"
                     /db_xref="MGI:MGI:1913546"
     exon            1..164
                     /gene="Haus2"
                     /gene_synonym="1700101G24Rik; 2410007P03Rik; Cep27"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..776
                     /gene="Haus2"
                     /gene_synonym="1700101G24Rik; 2410007P03Rik; Cep27"
                     /note="isoform a is encoded by transcript variant 1;
                     centrosomal protein of 27 kDa; centrosomal protein 27"
                     /codon_start=1
                     /product="HAUS augmin-like complex subunit 2 isoform a"
                     /protein_id="NP_079751.1"
                     /db_xref="CCDS:CCDS16624.1"
                     /db_xref="GeneID:66296"
                     /db_xref="MGI:MGI:1913546"
                     /translation="MAAANPWDPASSQTAAGLLLNHLVASGIVTKEMLDVSKKMAPCF
                     VNFSRLQQISDIQAEIYQNNLELELLKLEKDTADLIHPSHLIEKCDVLQSMNNHLEAV
                     LKEKHAIRQRLLRPMCQENLPLEAVYHRYVVHMLDLAVTFIEKFETHLETVKNSPHLD
                     ANLKQMSKALAKMDILVNKTEELAENILKWRELQTEISLYIPKMLTEERHLHELDIVP
                     PLPFFPKAHTETSRAK"
     exon            165..257
                     /gene="Haus2"
                     /gene_synonym="1700101G24Rik; 2410007P03Rik; Cep27"
                     /inference="alignment:Splign:2.1.0"
     exon            258..327
                     /gene="Haus2"
                     /gene_synonym="1700101G24Rik; 2410007P03Rik; Cep27"
                     /inference="alignment:Splign:2.1.0"
     exon            328..460
                     /gene="Haus2"
                     /gene_synonym="1700101G24Rik; 2410007P03Rik; Cep27"
                     /inference="alignment:Splign:2.1.0"
     exon            461..569
                     /gene="Haus2"
                     /gene_synonym="1700101G24Rik; 2410007P03Rik; Cep27"
                     /inference="alignment:Splign:2.1.0"
     exon            570..3155
                     /gene="Haus2"
                     /gene_synonym="1700101G24Rik; 2410007P03Rik; Cep27"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3135..3140
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Haus2"
                     /gene_synonym="1700101G24Rik; 2410007P03Rik; Cep27"
                     /note="hexamer: AATAAA"
     polyA_site      3155
                     /gene="Haus2"
                     /gene_synonym="1700101G24Rik; 2410007P03Rik; Cep27"
                     /note="major polyA site"
ORIGIN      
        1 catcaaaccg cgcgcctgtt cgcggtgttg cccctcactc ctcgcgccag ttccagaggt
       61 gtgcggaagc catggcggcc gccaacccgt gggacccagc gtcctcgcag actgcagctg
      121 ggttactgct aaaccacttg gtagcttcgg gcatagtcac taaggagatg ttagatgtat
      181 ctaagaaaat ggctccttgc tttgtgaact tttccagatt acaacagatc tcagatattc
      241 aagctgaaat ctaccagaac aatctggaac ttgaactttt gaagctagaa aaggatacag
      301 cagatcttat tcatccttcc catttgattg agaaatgtga tgttctgcaa agcatgaata
      361 atcatctgga agcagtgcta aaagagaagc atgccatcag gcaaagactg ctgagaccca
      421 tgtgccagga gaacttgcca ttggaagctg tttatcacag atatgtggta catatgttgg
      481 atctggctgt gactttcatt gagaaatttg aaacccatct tgaaacagtt aaaaatagcc
      541 ctcatttaga cgcaaaccta aagcaaatga gcaaagcttt agccaagatg gatattttgg
      601 tgaacaagac agaagaactg gcagagaata tactcaagtg gcgagaacta caaacagaaa
      661 tttccttgta tatccccaaa atgctaactg aagaacgcca tcttcatgaa cttgacatag
      721 tgcctccttt accttttttt cctaaggctc acaccgaaac ctccagggcc aagtgatgtc
      781 atctttactt tggattaatt acatgtagtc aaagaagtcc gtttctagat tgttgtgaca
      841 gggatattga tagtttttct tgctagcaat attaatggaa tagtggagcc agaaagatgt
      901 ctcagtggga aaaagctcct acttcaagcc ttccagcctg agttcagtcc ctgggatcca
      961 cattagcaga aggggatcac tgattcccac agatactcga tcctatggtg tccacacttg
     1021 tgtcatcata tgtatgtgcc tgtacacaca aaaatagaaa aatgaaagtg tgtgtgtgtg
     1081 tgtgtgtgtg tgtatgtatg tatgtatgta tgtgcacgcg cacatgagag agcgagcaca
     1141 ttggagtaca tatggcttca cttctttaca tgttttcact ctctttcttc agtgaagctt
     1201 aaaaatgata actgtggggc tggtgggttg gctcagggga taagagcact ggccactcta
     1261 ccacaggtcc tgagttcaat tcccagcaac cacaaggttg ctcaccacca tctataaggg
     1321 ggtctgatgc cctcttctgg cctgcagatg tatgtgcagc agagcactca cattgaatta
     1381 aaattgtttt actaacaaca aaaaagatta actatatgca tgatagttta ttataagtga
     1441 gttgaacatt cttcatacag aagattgtgt gctatgattc tgcattacat cttttaaaac
     1501 catttctgaa ttgaatgttc ctgaatctga aactgtcgtg attattcctg tgagattgta
     1561 gattagctac ataccaggac tgtaaccctt tgaagacttc gtaaagtggt ggttccttgg
     1621 ctgacccatc tagaaactta tgtaataaga ggctgagaag ggctcagttt gaacagactg
     1681 tacagtgtag tttgtgtggg atactttctt tccttctgag agcctaggat gttggtccgt
     1741 accaagtaga aagtaccttt ggtactggtc cctggcattg cagagcacct cgtccctaac
     1801 agttttgatg gtagatagca ttcaacaaat gtaacaaagc cgggtgtggt ggcgcgagcc
     1861 tttaatccca gcactctgga ggcagaggca ggcggatttc tgagttcgag gccagcctgg
     1921 tctacaaagt gagttccagg acagccaggg ctacacagag aaacactgtc tcgaaaaaac
     1981 aaaacaaaac aaaaaaaacc atgtaacagc tgagttgctg tactgagtca ctgctgtgag
     2041 tgatgacacc aagtctcata actcctcttg gcagatagat cactcactga acctggctgt
     2101 gttaggaaat aaacgctgag gaccaacaga gaagaaacgg agtcttcgtg taaaagttta
     2161 gaattctttg ttttggtact tcctatatgt agccaaggca gaacttgaac tcactatgtt
     2221 tcccagggtg gtctcaaaca catgattttc cttgcctctg ccgccctagt gctggaatca
     2281 cagacatgtg gtatcatatc tggctaaagt ttagaggttt gtaatggaaa atactaatat
     2341 attttaccta cttagggtta tttttatttt attattttag ggttattctt aagatggagg
     2401 caagtatact taaaagtaga gattgtaaca attgtctcaa gattttctca ctcatcagtc
     2461 ctgtaagtac ttcgccttat gtttaagcta ggatctgagt tcctttcaaa cgtgtgcatt
     2521 aggatttcct tactgtttta ttctgcactg tgggagtgta gcaaacctgc tcatcatgct
     2581 cttaatacaa gacttggtgc atagtaaagt agatgttcac aaggaagcag ggtctttacc
     2641 ctacccccaa cctccaaaag ggccctgcta aaacaataga ttattgtctt gaaagtctcc
     2701 cgcttttaca aatgtgccat ataagagtgg tgttaaagtt gggtgtggtg acgcacgcct
     2761 ttaatcccag cacttgggtg gcaaaggcag gcagatttct gagttcgagg ccagcctggt
     2821 ctacaaagtg agttccagga cagccagggc tatacagaga aaccctgact ccaaaacaaa
     2881 caaacaaaca aaaaaaccag agaaaccctg tcttcaaaaa ccaaaaaaaa aaaaaagtgg
     2941 tgttaaggtt ttgaacatca cctagccaag ttagtaaaat ctttatttgt atttcatctc
     3001 aattttttta actattcatt ttccttgtat gaattcttgt gtgttttatg tgtaaatata
     3061 ttcattattt tgacactatc aatattcttt gtggttttgt aatttttact tttattaatg
     3121 actcaagctg taaaaataaa ctaatttcaa ctaaaaaaaa aaaaaaaaaa
//
