LOCUS       NM_178255               1433 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus hyaluronan and proteoglycan link protein 3 (Hapln3),
            mRNA.
ACCESSION   NM_178255
VERSION     NM_178255.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1433)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1433)
  AUTHORS   Tang,T., Li,L., Tang,J., Li,Y., Lin,W.Y., Martin,F., Grant,D.,
            Solloway,M., Parker,L., Ye,W., Forrest,W., Ghilardi,N., Oravecz,T.,
            Platt,K.A., Rice,D.S., Hansen,G.M., Abuin,A., Eberhart,D.E.,
            Godowski,P., Holt,K.H., Peterson,A., Zambrowicz,B.P. and de
            Sauvage,F.J.
  TITLE     A mouse knockout library for secreted and transmembrane proteins
  JOURNAL   Nat Biotechnol 28 (7), 749-755 (2010)
   PUBMED   20562862
REFERENCE   3  (bases 1 to 1433)
  AUTHORS   Czipri,M., Otto,J.M., Cs-Szabo,G., Kamath,R.V., Vermes,C.,
            Firneisz,G., Kolman,K.J., Watanabe,H., Li,Y., Roughley,P.J.,
            Yamada,Y., Olsen,B.R. and Glant,T.T.
  TITLE     Genetic rescue of chondrodysplasia and the perinatal lethal effect
            of cartilage link protein deficiency
  JOURNAL   J Biol Chem 278 (40), 39214-39223 (2003)
   PUBMED   12732630
REFERENCE   4  (bases 1 to 1433)
  AUTHORS   Spicer,A.P., Joo,A. and Bowling,R.A. Jr.
  TITLE     A hyaluronan binding link protein gene family whose members are
            physically linked adjacent to chondroitin sulfate proteoglycan core
            protein genes: the missing links
  JOURNAL   J Biol Chem 278 (23), 21083-21091 (2003)
   PUBMED   12663660
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AY262757.1.
            
            On Jun 19, 2003 this sequence version replaced NM_178255.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY262757.1, AK136956.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164134 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..1433
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 44.9 cM"
     gene            1..1433
                     /gene="Hapln3"
                     /gene_synonym="4930554N11Rik; Lpr3"
                     /note="hyaluronan and proteoglycan link protein 3"
                     /db_xref="GeneID:67666"
                     /db_xref="MGI:MGI:1914916"
     exon            1..112
                     /gene="Hapln3"
                     /gene_synonym="4930554N11Rik; Lpr3"
                     /inference="alignment:Splign:2.1.0"
     exon            113..294
                     /gene="Hapln3"
                     /gene_synonym="4930554N11Rik; Lpr3"
                     /inference="alignment:Splign:2.1.0"
     CDS             171..1250
                     /gene="Hapln3"
                     /gene_synonym="4930554N11Rik; Lpr3"
                     /EC_number="3.1.2.15"
                     /note="link protein 3"
                     /codon_start=1
                     /product="hyaluronan and proteoglycan link protein 3
                     precursor"
                     /protein_id="NP_839986.2"
                     /db_xref="CCDS:CCDS21378.1"
                     /db_xref="GeneID:67666"
                     /db_xref="MGI:MGI:1914916"
                     /translation="MSLLFLVLLSPFPCVLGLPFYNGFYYSNDLSGRTLGNGYGEGLF
                     NGVKLVVETTEESLFSHQGASVTLPCHYHYEPALASPRHVRVKWWKLSENGAPEQDVL
                     VVIGQRHRSFGDYQGRVQLRQDKQQEVSLELRDLRLEDSGRYRCEVIDGLEDESGLVE
                     LELRGVVFPYQSREGRYQLNFHEAQQACQEQGAMVATFEQLFRAWEEGLDWCNAGWLQ
                     DASVQYPIVLPRQPCGGLGLAPGVRSYGQRHHRLHRYDVFCFAAALKGRVYYLENPKK
                     LTLLEAREACQEDGAQISTVGQLFAAWKFRGLDRCDAGWLADGSARYPIVHPRLNCGP
                     PEPGVRTFGFPDPHTRYGVYCYVQH"
     exon            295..663
                     /gene="Hapln3"
                     /gene_synonym="4930554N11Rik; Lpr3"
                     /inference="alignment:Splign:2.1.0"
     exon            664..966
                     /gene="Hapln3"
                     /gene_synonym="4930554N11Rik; Lpr3"
                     /inference="alignment:Splign:2.1.0"
     exon            967..1433
                     /gene="Hapln3"
                     /gene_synonym="4930554N11Rik; Lpr3"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 aggccattca agatcccaaa ttcttctgct gcttcggacc tggacagcct gtggcctcag
       61 cgtgtcgcag tggccccaag cgttggagcc gtcgaagagc tttctgggga cgttttccca
      121 gggcccagcc tcgtctaaga gaccctggca ctgccaccat cctggccggg atgagcctgc
      181 tgttccttgt ccttctctcg ccatttccct gcgttttggg acttccattc tacaatggct
      241 tctactattc caatgatctg agtggcagga ccctgggaaa tggctacggg gaaggcctat
      301 tcaatggcgt gaagttagtg gtggagacga cggaggagtc cctgttcagt caccaaggag
      361 ccagcgtgac cctgccctgc cactaccact atgagccagc cctggcatcc ccaagacatg
      421 tgcgtgttaa gtggtggaag ttgtcagaga atggagcccc agaacaggac gtgctggtgg
      481 tcatcgggca gaggcaccgc tcctttgggg actaccaagg gcgagttcaa ctgagacagg
      541 acaagcagca ggaagtctcg ctggagcttc gagacctgcg gctggaggac tctgggcgct
      601 accgctgcga ggtcatcgat ggcctggaag atgagagtgg cctggtagag ctggagcttc
      661 ggggtgtggt ttttccctac cagtcccgcg aagggcgcta ccagctcaac ttccacgagg
      721 cccaacaggc ctgccaggag cagggtgcta tggtagccac ttttgagcag cttttccgag
      781 cctgggagga aggcctagac tggtgcaatg caggctggct gcaggatgcc tccgtgcagt
      841 acccaatagt gctgccccgg cagccctgtg gaggcctggg tctggcacct ggtgttcgca
      901 gctatggcca gcgccaccac cgcctgcatc gttatgatgt gttctgcttt gctgctgccc
      961 tcaaggggcg ggtgtactac ctggagaacc ccaagaagct gacgctgctg gaggcccggg
     1021 aggcctgtca ggaagatggt gcacagatct ccacggtggg ccagctcttt gcggcttgga
     1081 agttccgtgg cctggatcgt tgtgatgctg gctggctggc agacggaagt gcccgctacc
     1141 ctatagttca ccctcgactc aactgtggcc cccctgagcc tggagtacgg acctttggct
     1201 tcccagaccc ccacacccgc tatggtgtct actgctatgt ccagcattag cagggtggct
     1261 agctgtacat ctgctctgcc cctgacttcc tgggctgagt gtttatcagg tggaccattg
     1321 tcccttgtgg gttgggggat tgcttggata gtttttatac ttcccaactt aaacatttaa
     1381 aggtattatt attatgatta ttatttaaaa gtattattat tattttattt tac
//
