LOCUS       NM_001271433            1336 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus hydroxyacylglutathione hydrolase-like (Haghl),
            transcript variant 1, mRNA.
ACCESSION   NM_001271433
VERSION     NM_001271433.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1336)
  AUTHORS   Lewandowski,J.P., Du,F., Zhang,S., Powell,M.B., Falkenstein,K.N.,
            Ji,H. and Vokes,S.A.
  TITLE     Spatiotemporal regulation of GLI target genes in the mammalian limb
            bud
  JOURNAL   Dev Biol 406 (1), 92-103 (2015)
   PUBMED   26238476
REFERENCE   2  (bases 1 to 1336)
  AUTHORS   Miller,J.A., Nathanson,J., Franjic,D., Shim,S., Dalley,R.A.,
            Shapouri,S., Smith,K.A., Sunkin,S.M., Bernard,A., Bennett,J.L.,
            Lee,C.K., Hawrylycz,M.J., Jones,A.R., Amaral,D.G., Sestan,N.,
            Gage,F.H. and Lein,E.S.
  TITLE     Conserved molecular signatures of neurogenesis in the hippocampal
            subgranular zone of rodents and primates
  JOURNAL   Development 140 (22), 4633-4644 (2013)
   PUBMED   24154525
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY265614.1, BC083322.1 and AI844861.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (a). Variants 1 and 2 encode the same isoform (a).
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC030466.1, BU519286.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164138, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            gene product(s) localized to mito. :: inferred from homology
            RefSeq Select criteria             :: based on conservation,
                                                  expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-61                BY265614.1         1-61
            62-1308             BC083322.1         1-1247
            1309-1336           AI844861.1         1-28                c
FEATURES             Location/Qualifiers
     source          1..1336
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 12.88 cM"
     gene            1..1336
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /note="hydroxyacylglutathione hydrolase-like"
                     /db_xref="GeneID:68977"
                     /db_xref="MGI:MGI:1919877"
     exon            1..159
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            160..350
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             246..1097
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /EC_number="3.1.2.6"
                     /note="isoform a is encoded by transcript variant 1;
                     hydroxyacylglutathione hydrolase-like protein"
                     /codon_start=1
                     /product="hydroxyacylglutathione hydrolase-like protein
                     isoform a"
                     /protein_id="NP_001258362.1"
                     /db_xref="CCDS:CCDS28527.1"
                     /db_xref="GeneID:68977"
                     /db_xref="MGI:MGI:1919877"
                     /translation="MKVKVIPVLEDNYMYLIIEEHTREAVAIDVAVAERLLEIAGREG
                     VSLTMVLSTHHHWDHTRGNAELAHILPGLAVLGADERICALTRRLEHGEGLQFGAIHV
                     RCLLTPGHTSGHMSYFLWEDDCPDSPALFSGDALSVAGCGWHLEDTAQQMYQSLAKTL
                     GTLPPETKVFCGHEHTLSNLEFAQKVEPCNEHVQAKLSWAQERDDEDIPTVPSTLGEE
                     LMYNPFLRVTEDAVRAFTGQVAPAQVLEALCRERARFQPAVEPPQPQVRALLALQWGL
                     LSTHQKK"
     exon            351..415
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            416..533
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            534..642
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            643..746
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            747..848
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            849..928
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            929..1320
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1266..1271
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /note="hexamer: AATAAA"
     polyA_site      1320
                     /gene="Haghl"
                     /gene_synonym="1500017E18Rik; 2810014I23Rik;
                     C330022E15Rik"
                     /note="major polyA site"
ORIGIN      
        1 atgcgcagtt ccagccgtcg tccatcaggt ctccgcagta ctctttcagg atcgcgacag
       61 ggaagtggtg atgtcgcggt gggcagcggc cacactccag gactagatcg gcggctcttg
      121 tgcgagtgag gggaacagca gggaacgagg tccacccagt gtgtgtgtgg ctgacccggc
      181 tcgtgcaact caggagaagg gattcactag gttgaaaaag tgcagactgg ctgaggtctg
      241 cgaccatgaa ggtcaaagtc atcccggtac ttgaagacaa ctacatgtac ctgatcattg
      301 aggaacacac gcgggaggcc gtagctatag acgtggctgt ggccgagagg ttgctggaga
      361 ttgcgggtcg cgagggagtg tctctgacca tggtgctgtc cacccatcat cactgggacc
      421 acacacgtgg aaatgcggag ctggcacaca ttctgccagg attggctgtc ttgggagcag
      481 atgagcgcat ttgcgctcta acccgaaggc tggaacatgg agaagggctt cagtttgggg
      541 ccatccacgt gcgatgcctc ttgacgccag gccacacctc tggccacatg agctacttcc
      601 tgtgggagga tgactgcccg gactcaccag ccctcttctc tggggatgct ctgtcagtgg
      661 caggctgtgg ctggcacctg gaggacactg cccagcagat gtaccagagc ttggccaaga
      721 ctctgggtac ccttccaccc gagacgaagg tgttctgtgg tcatgagcat acgctgagca
      781 atcttgagtt tgcacagaaa gtggagccct gcaacgaaca cgtgcaagct aagctgtcct
      841 gggcccagga gagggatgac gaggatattc ctactgtgcc ttcgacgctg ggcgaggagc
      901 tcatgtacaa ccctttcctg agggtgacag aggatgcagt ccgtgcgttc acaggccagg
      961 tggccccagc ccaggtcctg gaggccctct gcagggagcg agcgcgcttc cagcctgctg
     1021 tggagccacc acagccgcag gttcgggcac tcctggcctt acagtggggg cttctgagca
     1081 cacaccagaa aaagtgaact atgtggggaa ccggcttgtc cccacactcc cccagggacc
     1141 cctgccaccc tgctttgaag aaccagcaag tggtgtcttg tctctactgc tcatggagcc
     1201 ctataagtgg gatctgtagg agctcttgtg ggtccagaga catatcctgg ggactgagga
     1261 gggtgaataa aactttgaaa ggcccagtgt ggtaccagac acacagtgga tccttccaga
     1321 aaaaaaaaaa aaaaaa
//
