LOCUS       NM_019986               2584 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus hyaluronic acid binding protein 4 (Habp4), mRNA.
ACCESSION   NM_019986
VERSION     NM_019986.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2584)
  AUTHORS   Melo-Hanchuk,T.D., Colleti,C., Saito,A., Mendes,M.C.S.,
            Carvalheira,J.B.C., Vassallo,J. and Kobarg,J.
  TITLE     Intracellular hyaluronic acid-binding protein 4 (HABP4): a
            candidate tumor suppressor in colorectal cancer
  JOURNAL   Oncotarget 11 (46), 4325-4337 (2020)
   PUBMED   33245729
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 2584)
  AUTHORS   Distler,U., Schmeisser,M.J., Pelosi,A., Reim,D., Kuharev,J.,
            Weiczner,R., Baumgart,J., Boeckers,T.M., Nitsch,R., Vogt,J. and
            Tenzer,S.
  TITLE     In-depth protein profiling of the postsynaptic density from mouse
            hippocampus using data-independent acquisition proteomics
  JOURNAL   Proteomics 14 (21-22), 2607-2613 (2014)
   PUBMED   25211037
REFERENCE   3  (bases 1 to 2584)
  AUTHORS   Chew,T.G., Peaston,A., Lim,A.K., Lorthongpanich,C., Knowles,B.B.
            and Solter,D.
  TITLE     A tudor domain protein SPINDLIN1 interacts with the mRNA-binding
            protein SERBP1 and is involved in mouse oocyte meiotic resumption
  JOURNAL   PLoS One 8 (7), e69764 (2013)
   PUBMED   23894536
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 2584)
  AUTHORS   Chiellini,C., Costa,M., Novelli,S.E., Amri,E.Z., Benzi,L.,
            Bertacca,A., Cohen,P., Del Prato,S., Friedman,J.M. and Maffei,M.
  TITLE     Identification of cathepsin K as a novel marker of adiposity in
            white adipose tissue
  JOURNAL   J Cell Physiol 195 (2), 309-321 (2003)
   PUBMED   12652657
REFERENCE   5  (bases 1 to 2584)
  AUTHORS   Marshall,K.E., Godden,E.L., Yang,F., Burgers,S., Buck,K.J. and
            Sikela,J.M.
  TITLE     In silico discovery of gene-coding variants in murine quantitative
            trait loci using strain-specific genome sequence databases
  JOURNAL   Genome Biol 3 (12), RESEARCH0078 (2002)
   PUBMED   12537567
REFERENCE   6  (bases 1 to 2584)
  AUTHORS   Huang,L., Grammatikakis,N., Yoneda,M., Banerjee,S.D. and Toole,B.P.
  TITLE     Molecular characterization of a novel intracellular
            hyaluronan-binding protein
  JOURNAL   J Biol Chem 275 (38), 29829-29839 (2000)
   PUBMED   10887182
REFERENCE   7  (bases 1 to 2584)
  AUTHORS   Gogstad,G.O., Hagen,I., Korsmo,R. and Solum,N.O.
  TITLE     Characterization of the proteins of isolated human platelet
            alpha-granules. Evidence for a separate alpha-granule-pool of the
            glycoproteins IIb and IIIa
  JOURNAL   Biochim Biophys Acta 670 (2), 150-162 (1981)
   PUBMED   6457647
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK016800.1, AK146525.1 and CD776978.1.
            
            On Nov 15, 2007 this sequence version replaced NM_019986.2.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR1660817.138000.1,
                                           SRR1660817.11180.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1116              AK016800.1         44-1159
            1117-2028           AK146525.1         1090-2001
            2029-2584           CD776978.1         1-556               c
FEATURES             Location/Qualifiers
     source          1..2584
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 33.26 cM"
     gene            1..2584
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /note="hyaluronic acid binding protein 4"
                     /db_xref="GeneID:56541"
                     /db_xref="MGI:MGI:1891713"
     exon            1..469
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             121..1359
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /note="intracellular hyaluronan-binding protein p57;
                     IHABP4; IHABP-4; hyaluronic acid-binding protein 4
                     (intracellular)"
                     /codon_start=1
                     /product="intracellular hyaluronan-binding protein 4"
                     /protein_id="NP_064370.2"
                     /db_xref="CCDS:CCDS36702.1"
                     /db_xref="GeneID:56541"
                     /db_xref="MGI:MGI:1891713"
                     /translation="MKGALGSPVAAAGAAMQETFGCVVANRFHQLLDDESDPFDILRE
                     AEHRRQQQLQRKRRDEAAAAASGAGHRGGRSPAVASGHRPGAGGRRESQKERKSLAAS
                     GAQQPDSPGGPQPPGQKRTPRRGEQQGWNDNRGTDVVLERAERRSYREYRPYETERQA
                     DLPVEKFTDEKPVDRFDRDRPLRGRGGPRGGLRSRGRGGPGNRAFDSFDQRGKRDFER
                     YSSNDKTNRMEDSMGGCGIRPWGSGKDTSDTEPPAPMEETSMMEECQGALDEESAAKV
                     PELEVEEENQVQEMTLDEWKNLQEQTRPKPEFNIRKPESTVPSKAVVIHKSRYRDDMV
                     KEDYEDESHVFRKAANDITSQLEINFGNLPRPGRGARGSTRGGRGRMRRTENYGPRAE
                     VVTQDVAPNPDDPEDFPALA"
     exon            470..632
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            633..791
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            792..860
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            861..944
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            945..1116
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1117..1302
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            1303..2567
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1434..1439
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /note="hexamer: AATAGA"
     polyA_site      1464
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
     regulatory      2544..2549
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /note="hexamer: ATTAAA"
     polyA_site      2567
                     /gene="Habp4"
                     /gene_synonym="4933413D03Rik; 4933428J01Rik"
                     /note="major polyA site"
ORIGIN      
        1 cgagagtgcg gcggcggcgg cggcggcggc ggcagcagca gcagcagcat gggtcctcgc
       61 ccgcggcttc gctgaacctc actggcctgg gctgcccgcg gcgcccgcag cggcggcgtc
      121 atgaaggggg ccctggggag ccctgtagcc gccgcgggcg ccgcgatgca ggagacgttc
      181 ggctgcgtcg tggccaaccg cttccatcag ctgctggacg acgagtcgga cccgttcgac
      241 atcctgcggg aggccgagca ccggcgccag cagcagctgc agcgcaagcg tcgcgatgag
      301 gcggcggcgg cggccagcgg ggccgggcac cgtggcggca ggagcccggc tgtggcctca
      361 ggacacaggc ctggcgcagg cggccgcagg gagtcgcaga aggagcgcaa gagcctcgcg
      421 gcgtccggcg cacagcagcc agacagccct gggggcccgc agccgccagg ccagaagcgg
      481 actcctcgaa gaggggagca gcaaggatgg aatgacaaca gggggacaga cgtggtgctt
      541 gaaagagcag agcgaaggtc ctacagggaa taccggccct atgagactga gagacaggct
      601 gacttgccag tggagaagtt taccgatgaa aaaccagttg acaggtttga tcgagacaga
      661 ccactgagag gacgtggagg ccccagagga ggcctgagga gcagaggccg aggcggtcct
      721 gggaacagag cttttgactc ctttgaccaa agagggaaac gagactttga gagatacagt
      781 agcaatgata aaacaaacag aatggaggac agcatgggtg gctgtggcat tcgcccctgg
      841 ggatcaggta aagacactag tgatacagag ccacctgcac ccatggaaga gacctcgatg
      901 atggaggagt gccagggcgc cctggacgag gagtctgcag ccaaagttcc tgagttggag
      961 gtagaagagg aaaaccaagt ccaagagatg accttagatg agtggaaaaa ccttcaagaa
     1021 caaaccagac caaagcctga gttcaatatt cggaagccag agtccacagt tccttccaag
     1081 gcagtggtga ttcacaagtc cagatacaga gacgatatgg tgaaggagga ctatgaggat
     1141 gagtctcacg tcttccggaa agctgccaat gacatcacat cccagctgga gattaacttt
     1201 ggtaacctcc ctcgccctgg tcggggagcc agaggcagca cccggggagg ccgagggaga
     1261 atgagaagaa cagagaacta tggcccccgt gcagaagtgg tgacccaaga tgttgctccc
     1321 aacccggatg accctgagga cttccccgcc ctggcctaac agccactccc ctgcagcaga
     1381 gcagcactat gaagagactt tccttgccgc gagaagagtc agactctaag aacaatagat
     1441 gttgcttttc ccgtgtcgtg tgaagtcatt gcactttttt gctctgtgga gttcccatga
     1501 ggtcaggccc tttccccaga tagagacttt tgtaagggat aatgtttaaa atgtgtacat
     1561 agattctaac aatcccagca cagaagtaca aagtaaagta agttagaaaa tagaactgct
     1621 gggcgtggtg gcgcacgcct ttaaacctag cacttgggag gcagtggcag gcagatcccg
     1681 agttcaaggc cagcctggtc tacagagtga gtcttgaaaa acaagacgag aaaagtcctt
     1741 gagtatttca ggacacgtgg agaaccgctc atgtagagca gtcccacccc taattttcat
     1801 accattcacc tgctactgct caattctgag aaaatccctg agttgtggtt tagacattgt
     1861 gcactaggga caaccactct gaagcagagg aagtgtactg gttttcagta gtgatttaaa
     1921 ctacctcgtg gtctgtgcgt gcacacatcc tcagtatgtg tgagcagact tagggttcag
     1981 gtggttgttg aatataatca aatgaaaagg tttcctgtat ttccccccca acccccgtca
     2041 acactagtgt tggaattcag cactgtggac tctgagcaga ctgacttgta actcagtcac
     2101 atctcctgac tgcgaacatg ggctgggccc tcccctcggc tgggccccag ttccggtgtt
     2161 gttcttaagg cctctggtgg aggtttaagg ttagggacca cctcagaggc tcaatcaccc
     2221 caaacagctt gagacctagg gccggccacc cacccaccgg caaaactagg gaagattcat
     2281 tgtatgtggg agggacgagc caaggtgttg ggcagctgtc gagattagga agggaggttt
     2341 gcctgttgtg cttgcaatgg aaccctgctc cccagacctg tgctacccgc cttggccaca
     2401 aagtctgaga tggtgctgaa ctggaaccca ggtataaatg aaggttggta ttgtattccc
     2461 tctgaactct tggggtttgg ttgagtcatc aaagttgatg aggatgttgc tttgggtgac
     2521 cacctgcttc tgaccccatg tttattaaat gaatgagtat aaaggtaaaa aaaaaaaaaa
     2581 aaaa
//
