LOCUS       NM_001204916            2817 bp    mRNA    linear   ROD 06-FEB-2024
DEFINITION  Mus musculus histocompatibility 60c (H60c), mRNA.
ACCESSION   NM_001204916 XM_001476279 XM_003085671
VERSION     NM_001204916.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2817)
  AUTHORS   Hansen,C.H., Holm,T.L., Krych,L., Andresen,L., Nielsen,D.S.,
            Rune,I., Hansen,A.K. and Skov,S.
  TITLE     Gut microbiota regulates NKG2D ligand expression on intestinal
            epithelial cells
  JOURNAL   Eur J Immunol 43 (2), 447-457 (2013)
   PUBMED   23136011
REFERENCE   2  (bases 1 to 2817)
  AUTHORS   Yoshida,S., Mohamed,R.H., Kajikawa,M., Koizumi,J., Tanaka,M.,
            Fugo,K., Otsuka,N., Maenaka,K., Yagita,H., Chiba,H. and Kasahara,M.
  TITLE     Involvement of an NKG2D ligand H60c in epidermal dendritic T
            cell-mediated wound repair
  JOURNAL   J Immunol 188 (8), 3972-3979 (2012)
   PUBMED   22403443
  REMARK    GeneRIF: a more general role for H60c in the maintenance of
            epithelial integrity.
REFERENCE   3  (bases 1 to 2817)
  AUTHORS   Takada,A., Yoshida,S., Kajikawa,M., Miyatake,Y., Tomaru,U.,
            Sakai,M., Chiba,H., Maenaka,K., Kohda,D., Fugo,K. and Kasahara,M.
  TITLE     Two novel NKG2D ligands of the mouse H60 family with differential
            expression patterns and binding affinities to NKG2D
  JOURNAL   J Immunol 180 (3), 1678-1685 (2008)
   PUBMED   18209064
  REMARK    GeneRIF: Identified two novel mouse chromosome 10-encoded NKG2D
            ligands, H60b and H60c, structurally resembling H60.
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK014573.1, AB284506.1 and AC157021.6.
            
            On Jul 23, 2011 this sequence version replaced NM_001204916.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB284506.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849387, SAMN01164133
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: experimental evidence
                                                (PMID:18209064)
            RefSeq Select criteria           :: based on computational evidence
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-21                AK014573.1         2-22
            22-1095             AB284506.1         1-1074
            1096-1224           AK014573.1         663-791
            1225-1225           AC157021.6         129528-129528
            1226-2817           AK014573.1         793-2384
FEATURES             Location/Qualifiers
     source          1..2817
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 2.08 cM"
     gene            1..2817
                     /gene="H60c"
                     /gene_synonym="4632413I24Rik; 670558; Gm9491"
                     /note="histocompatibility 60c"
                     /db_xref="GeneID:670558"
                     /db_xref="MGI:MGI:3774845"
     exon            1..126
                     /gene="H60c"
                     /gene_synonym="4632413I24Rik; 670558; Gm9491"
                     /inference="alignment:Splign:2.1.0"
     exon            127..236
                     /gene="H60c"
                     /gene_synonym="4632413I24Rik; 670558; Gm9491"
                     /inference="alignment:Splign:2.1.0"
     CDS             197..790
                     /gene="H60c"
                     /gene_synonym="4632413I24Rik; 670558; Gm9491"
                     /note="histocompatibility antigen 60c"
                     /codon_start=1
                     /product="histocompatibility antigen 60c precursor"
                     /protein_id="NP_001191845.1"
                     /db_xref="CCDS:CCDS56668.1"
                     /db_xref="GeneID:670558"
                     /db_xref="MGI:MGI:3774845"
                     /translation="MALLLLILESCSAGTYALNCKLTVKYRTLQGLCSVNGKTFLDFG
                     DENHEGNATMLCPALYQSLTDISEVMWSLQSGNDALNVTTRSQYYQGEFIDGFWDINT
                     DEQHSIYVYPLNKTWRESHSDNSSAMEQWKNKNLEKDIRNVLMVDFSCCLNKSSPHFR
                     EMPTLPTTAAHVDQPRSMACKSSPFDGLIMILLIYIL"
     exon            237..422
                     /gene="H60c"
                     /gene_synonym="4632413I24Rik; 670558; Gm9491"
                     /inference="alignment:Splign:2.1.0"
     exon            423..686
                     /gene="H60c"
                     /gene_synonym="4632413I24Rik; 670558; Gm9491"
                     /inference="alignment:Splign:2.1.0"
     exon            687..824
                     /gene="H60c"
                     /gene_synonym="4632413I24Rik; 670558; Gm9491"
                     /inference="alignment:Splign:2.1.0"
     exon            825..2817
                     /gene="H60c"
                     /gene_synonym="4632413I24Rik; 670558; Gm9491"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agacacacct atttctcccc cacggtgcag ccaccagttt ctccctcagc ctgccagcga
       61 tcccagcaga aggcatcaat tttattgttc gttcctgctt ctgatattga tggtctctgg
      121 gcactgtcac gcctgccttc agctggctcc agtcatcgaa ggcaatgctc gcaatgctgg
      181 caatgctctg cttgttatgg ctctacttct cttgatcctg gagtcctgta gtgcaggcac
      241 atatgcccta aattgcaaac tcactgtcaa gtatcgtact ctacaaggac tgtgctcagt
      301 gaatggaaag actttccttg attttggtga tgaaaaccat gagggaaatg ccactatgct
      361 gtgtcctgct ttataccaaa gcctgacaga tatttcagaa gtaatgtgga gcctgcaatc
      421 aggtaatgat gccttgaatg tcacaacaag atctcagtat tatcaaggag aattcattga
      481 tggattctgg gacatcaaca ctgatgaaca gcatagcatc tacgtttatc cacttaataa
      541 gacctggaga gaaagtcatt ctgataacag cagtgccatg gagcagtgga agaacaagaa
      601 cctagaaaaa gatatcagga atgtcctcat ggtagatttc agttgctgcc tcaacaaatc
      661 gtcgccacac tttagagaaa tgccaacctt gccaaccact gctgcacatg tggaccagcc
      721 tcgatccatg gcatgcaagt ccagcccctt tgatgggttg ataatgatat tgctcatcta
      781 catcctctag cgtgttttct aaggagaatt cttgacagag acagggtgaa gatgctccag
      841 agaaagtcgt gacaattcat cgggtgcagc cactgcccct tttcgtcatc ctcaacatat
      901 gactcatcat gctacagaca tagtatttca aggcctttcc actgtgtgct aggcactgtg
      961 gcccttgcta atcacaggtt cctttttctc tgggtgattt gtccataaca tgcaattact
     1021 tgatctagag atttggaaaa aatatattta tgtatccata ccaaccataa aaaaaacaac
     1081 aagaacagaa taatcaaatc tctttagtgg gagtgtgaag tctttactcc tgtataatcc
     1141 atcagtgtct atgtaattct gagactgtct aggagaagcc tgcacaaggc aatgttctct
     1201 ataccatcaa tgaaaaatag atatatgcgc cattttatat gactatatat gatagaaaaa
     1261 aaactacttt ataacataag gtgaaagttt ttattattat tactattata ggttagtttg
     1321 tgtgataagc actaagtagc ccagccatgg ccacatgtac actggtgcag cagagaactt
     1381 ggaacctgct ctgtccgaca ggctggttgc ccctgcagtg gcaatctggc agtgaaatct
     1441 ggaaggtcct gggcagctgt cactactgag tccacaccct ctgatgcagg ttctgggtca
     1501 gtgttgcttt cccctgtgct gagagcatct tctttgtgca catacagaag ctgtggtaca
     1561 ggagagtgaa ctcacgattg ttctctctga cctcggcata ggcacttttg cacaagtgca
     1621 ctagcactca cacatcctaa aaacgtggag attgtagagt gtttgttcac tgttgaaata
     1681 ctgtgttttt tgaagcaagg tctcactctg tagacaaggc tggcctggac ctcacagaaa
     1741 aacaccttgc cagcattaag cttaaagacg tgtgtcacca tgcctgagtg atcacaggat
     1801 tttaagctct aatggtgtgc tactcaagta ttagagattt aaaattgtct ttttcacaca
     1861 gacggtcatg tttctgagaa tgggtgctcc ctattaattt gtgaacttta gtggcactga
     1921 gttgatgggt attattatgt atctgaggaa tcactaaagg gatctaagcc taggaaacag
     1981 aaattgagga gtgtttgttt agtagaagta aatggtaact acatcaggtc cccagacctt
     2041 agcacaactg actccattgt ggaagtgtta ttcaggctgt aaaactcagc acacagacat
     2101 cacctacagc caaaatgaaa acaaagacct catccaccaa agtccatggt tctgagatgt
     2161 ctctaattgc aacaactttg ctctttggct tttgtagttc tgcttctgac taacttcctg
     2221 gcaactgaag tatatcaacc cagaatggtt tttgtgctta aaagatctcc ctggttaaag
     2281 ctccattcta tactggaacg ccaaaaattt agaataatca gggccagcta ataaagagtt
     2341 tctattggct taaataccat tgttcgggga gttaggtagt ggaggaagca cggaagggag
     2401 actgcaaaca ggaaataaag taattaatct aaaaaacatc ggagcattct tcttggctga
     2461 attcccctag aacagcaatg tcctttctgc agtttcctta ctagaaggct cttaccgctg
     2521 gctctggatg tctaactgct gacttgtatc tttaaatgga tctctctctc tttagacgtt
     2581 tgctaacttt cttcaggtga ttggttttca ggtgttcagg ttcctgcgaa tgggtgctgt
     2641 ctgtattata caatgtgtac ttgaaatttt cataatattt tcagagtatt ctattgtaat
     2701 tatattacct tacaagattt gtggggcttc tctttgattt gtgattacac agttttagta
     2761 tattttgtgt tctttagtca gactatgcaa ttgtctatga agttcagtaa acttttg
//
