LOCUS       NM_153173                435 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus H4 clustered histone 8 (H4c8), mRNA.
ACCESSION   NM_153173 NM_178209
VERSION     NM_153173.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 435)
  AUTHORS   Liu,L.J., Xie,R., Hussain,S., Lian,J.B., Rivera-Perez,J.,
            Jones,S.N., Stein,J.L., Stein,G.S. and van Wijnen,A.J.
  TITLE     Functional coupling of transcription factor HiNF-P and histone H4
            gene expression during pre- and post-natal mouse development
  JOURNAL   Gene 483 (1-2), 1-10 (2011)
   PUBMED   21605641
REFERENCE   2  (bases 1 to 435)
  AUTHORS   Quille,M.L., Carat,S., Quemener-Redon,S., Hirchaud,E., Baron,D.,
            Benech,C., Guihot,J., Placet,M., Mignen,O., Ferec,C., Houlgatte,R.
            and Friocourt,G.
  TITLE     High-throughput analysis of promoter occupancy reveals new targets
            for Arx, a gene mutated in mental retardation and
            interneuronopathies
  JOURNAL   PLoS One 6 (9), e25181 (2011)
   PUBMED   21966449
REFERENCE   3  (bases 1 to 435)
  AUTHORS   Kim,S.C., Sprung,R., Chen,Y., Xu,Y., Ball,H., Pei,J., Cheng,T.,
            Kho,Y., Xiao,H., Xiao,L., Grishin,N.V., White,M., Yang,X.J. and
            Zhao,Y.
  TITLE     Substrate and functional diversity of lysine acetylation revealed
            by a proteomics survey
  JOURNAL   Mol Cell 23 (4), 607-618 (2006)
   PUBMED   16916647
REFERENCE   4  (bases 1 to 435)
  AUTHORS   Ancelin,K., Lange,U.C., Hajkova,P., Schneider,R., Bannister,A.J.,
            Kouzarides,T. and Surani,M.A.
  TITLE     Blimp1 associates with Prmt5 and directs histone arginine
            methylation in mouse germ cells
  JOURNAL   Nat Cell Biol 8 (6), 623-630 (2006)
   PUBMED   16699504
REFERENCE   5  (bases 1 to 435)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   6  (bases 1 to 435)
  AUTHORS   Suto,R.K., Clarkson,M.J., Tremethick,D.J. and Luger,K.
  TITLE     Crystal structure of a nucleosome core particle containing the
            variant histone H2A.Z
  JOURNAL   Nat Struct Biol 7 (12), 1121-1124 (2000)
   PUBMED   11101893
REFERENCE   7  (bases 1 to 435)
  AUTHORS   Wang,Z.F., Krasikov,T., Frey,M.R., Wang,J., Matera,A.G. and
            Marzluff,W.F.
  TITLE     Characterization of the mouse histone gene cluster on chromosome
            13: 45 histone genes in three patches spread over 1Mb
  JOURNAL   Genome Res 6 (8), 688-701 (1996)
   PUBMED   8858344
REFERENCE   8  (bases 1 to 435)
  AUTHORS   Meier,V.S., Bohni,R. and Schumperli,D.
  TITLE     Nucleotide sequence of two mouse histone H4 genes
  JOURNAL   Nucleic Acids Res 17 (2), 795 (1989)
   PUBMED   2915930
REFERENCE   9  (bases 1 to 435)
  AUTHORS   Seiler-Tuyns,A. and Birnstiel,M.L.
  TITLE     Structure and expression in L-cells of a cloned H4 histone gene of
            the mouse
  JOURNAL   J Mol Biol 151 (4), 607-625 (1981)
   PUBMED   6276563
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL592149.8.
            
            On Feb 27, 2014 this sequence version replaced NM_153173.3.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Two molecules of each of the four core histones (H2A,
            H2B, H3, and H4) form an octamer, around which approximately 146 bp
            of DNA is wrapped in repeating units, called nucleosomes. The
            linker histone, H1, interacts with linker DNA between nucleosomes
            and functions in the compaction of chromatin into higher order
            structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H4
            family. Transcripts from this gene lack polyA tails but instead
            contain a palindromic termination element. [provided by RefSeq, Aug
            2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AA028777.1, AA022289.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-435               AL592149.8         11646-12080
FEATURES             Location/Qualifiers
     source          1..435
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 9.77 cM"
     gene            1..435
                     /gene="H4c8"
                     /gene_synonym="1700024H08Rik; H2c8; H4c1; H4c11; H4c12;
                     H4c14; H4c16; H4c2; H4c3; H4c4; H4c6; H4c9; H4f16;
                     Hist1h4h"
                     /note="H4 clustered histone 8"
                     /db_xref="GeneID:69386"
                     /db_xref="MGI:MGI:2448427"
     exon            1..435
                     /gene="H4c8"
                     /gene_synonym="1700024H08Rik; H2c8; H4c1; H4c11; H4c12;
                     H4c14; H4c16; H4c2; H4c3; H4c4; H4c6; H4c9; H4f16;
                     Hist1h4h"
                     /inference="alignment:Splign:2.1.0"
     CDS             72..383
                     /gene="H4c8"
                     /gene_synonym="1700024H08Rik; H2c8; H4c1; H4c11; H4c12;
                     H4c14; H4c16; H4c2; H4c3; H4c4; H4c6; H4c9; H4f16;
                     Hist1h4h"
                     /note="histone 1, H4h; H4 histone family, member A;
                     histone cluster 1, H4h"
                     /codon_start=1
                     /product="histone H4"
                     /protein_id="NP_694813.1"
                     /db_xref="CCDS:CCDS26340.1"
                     /db_xref="GeneID:69386"
                     /db_xref="MGI:MGI:2448427"
                     /translation="MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGV
                     KRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG
                     G"
ORIGIN      
        1 gaaaacactg catataagta atgtgcctgt gccttccact ctgttgaggt tttttcttca
       61 gcaagtacac catgtctggt cgtggcaagg gcggtaaagg tcttggcaaa ggcggcgcca
      121 agcgccaccg caaagtgctg cgtgacaaca tccagggcat cacgaagccc gccatccgcc
      181 gcctggcccg gcgcggggga gtgaagcgca tctccggcct catctacgag gagacccgcg
      241 gtgtgctgaa ggtgttcctg gagaacgtga tccgcgacgc cgtcacctac acggagcacg
      301 ccaagcgcaa gaccgtcacc gccatggacg tggtctacgc gctcaagcgc cagggccgca
      361 ccctctacgg attcggcggt taagcgaatc ttgcttctga cctacaaaac caaaggccct
      421 tttcagggcc gccca
//
