LOCUS       NM_175655                383 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus H4 clustered histone 6 (H4c6), mRNA.
ACCESSION   NM_175655
VERSION     NM_175655.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 383)
  AUTHORS   Liu,L.J., Xie,R., Hussain,S., Lian,J.B., Rivera-Perez,J.,
            Jones,S.N., Stein,J.L., Stein,G.S. and van Wijnen,A.J.
  TITLE     Functional coupling of transcription factor HiNF-P and histone H4
            gene expression during pre- and post-natal mouse development
  JOURNAL   Gene 483 (1-2), 1-10 (2011)
   PUBMED   21605641
REFERENCE   2  (bases 1 to 383)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL592149.8.
            
            On Jun 19, 2019 this sequence version replaced NM_175655.2.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Two molecules of each of the four core histones (H2A,
            H2B, H3, and H4) form an octamer, around which approximately 146 bp
            of DNA is wrapped in repeating units, called nucleosomes. The
            linker histone, H1, interacts with linker DNA between nucleosomes
            and functions in the compaction of chromatin into higher order
            structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H4
            family. Transcripts from this gene lack polyA tails but instead
            contain a palindromic termination element. [provided by RefSeq, Aug
            2015].
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-383               AL592149.8         31892-32274         c
FEATURES             Location/Qualifiers
     source          1..383
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 9.78 cM"
     gene            1..383
                     /gene="H4c6"
                     /gene_synonym="H4c1; H4c11; H4c12; H4c14; H4c16; H4c2;
                     H4c3; H4c4; H4c8; H4c9; H4f16; Hist1h4f"
                     /note="H4 clustered histone 6"
                     /db_xref="GeneID:319157"
                     /db_xref="MGI:MGI:2448425"
     exon            1..383
                     /gene="H4c6"
                     /gene_synonym="H4c1; H4c11; H4c12; H4c14; H4c16; H4c2;
                     H4c3; H4c4; H4c8; H4c9; H4f16; Hist1h4f"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..337
                     /gene="H4c6"
                     /gene_synonym="H4c1; H4c11; H4c12; H4c14; H4c16; H4c2;
                     H4c3; H4c4; H4c8; H4c9; H4f16; Hist1h4f"
                     /note="histone 1, H4f; histone cluster 1, H4f"
                     /codon_start=1
                     /product="histone H4"
                     /protein_id="NP_783586.1"
                     /db_xref="CCDS:CCDS26345.1"
                     /db_xref="GeneID:319157"
                     /db_xref="MGI:MGI:2448425"
                     /translation="MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGV
                     KRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG
                     G"
     polyA_site      383
                     /gene="H4c6"
                     /gene_synonym="H4c1; H4c11; H4c12; H4c14; H4c16; H4c2;
                     H4c3; H4c4; H4c8; H4c9; H4f16; Hist1h4f"
                     /note="major polyA site"
ORIGIN      
        1 aatttcaact cagtgctcca tagccatgtc tggtcgtggt aagggaggaa aaggcctggg
       61 caaaggcggc gctaagcgcc accgtaaggt tcttcgcgat aacatccagg gcatcaccaa
      121 gcccgccatc cgccgcctgg cccggcgcgg aggagtgaag cgcatctccg gtctcatcta
      181 cgaggaaacc cgcggtgtgc tgaaggtgtt cctggagaac gtgatccgcg acgccgtcac
      241 ctacacggag cacgccaagc gcaagaccgt caccgccatg gacgtggtct acgcgctcaa
      301 gcgccagggc cgcaccctct acggattcgg cggttaagct cacctggagc ttctttctca
      361 aaggcccttt tcagggccac cca
//
