LOCUS       NM_178208                375 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus H4 clustered histone 3 (H4c3), mRNA.
ACCESSION   NM_178208
VERSION     NM_178208.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 375)
  AUTHORS   Blackburn,J., Kawasaki,K., Porntaveetus,T., Kawasaki,M.,
            Otsuka-Tanaka,Y., Miake,Y., Ota,M.S., Watanabe,M., Hishinuma,M.,
            Nomoto,T., Oommen,S., Ghafoor,S., Harada,F., Nozawa-Inoue,K.,
            Maeda,T., Peterkova,R., Lesot,H., Inoue,J., Akiyama,T.,
            Schmidt-Ullrich,R., Liu,B., Hu,Y., Page,A., Ramirez,A., Sharpe,P.T.
            and Ohazama,A.
  TITLE     Excess NF-kappaB induces ectopic odontogenesis in embryonic incisor
            epithelium
  JOURNAL   J Dent Res 94 (1), 121-128 (2015)
   PUBMED   25376721
REFERENCE   2  (bases 1 to 375)
  AUTHORS   Sun,R. and Qi,H.
  TITLE     Dynamic expression of combinatorial replication-dependent histone
            variant genes during mouse spermatogenesis
  JOURNAL   Gene Expr Patterns 14 (1), 30-41 (2014)
   PUBMED   24140495
REFERENCE   3  (bases 1 to 375)
  AUTHORS   Huegel,J., Mundy,C., Sgariglia,F., Nygren,P., Billings,P.C.,
            Yamaguchi,Y., Koyama,E. and Pacifici,M.
  TITLE     Perichondrium phenotype and border function are regulated by Ext1
            and heparan sulfate in developing long bones: a mechanism likely
            deranged in Hereditary Multiple Exostoses
  JOURNAL   Dev Biol 377 (1), 100-112 (2013)
   PUBMED   23458899
REFERENCE   4  (bases 1 to 375)
  AUTHORS   Blackburn,J., Ohazama,A., Kawasaki,K., Otsuka-Tanaka,Y., Liu,B.,
            Honda,K., Rountree,R.B., Hu,Y., Kawasaki,M., Birchmeier,W.,
            Schmidt-Ullrich,R., Kinoshita,A., Schutte,B.C., Hammond,N.L.,
            Dixon,M.J. and Sharpe,P.T.
  TITLE     The role of Irf6 in tooth epithelial invagination
  JOURNAL   Dev Biol 365 (1), 61-70 (2012)
   PUBMED   22366192
REFERENCE   5  (bases 1 to 375)
  AUTHORS   Michikami,I., Fukushi,T., Honma,S., Yoshioka,S., Itoh,S.,
            Muragaki,Y., Kurisu,K., Ooshima,T., Wakisaka,S. and Abe,M.
  TITLE     Trps1 is necessary for normal temporomandibular joint development
  JOURNAL   Cell Tissue Res 348 (1), 131-140 (2012)
   PUBMED   22427063
REFERENCE   6  (bases 1 to 375)
  AUTHORS   Young,B., Minugh-Purvis,N., Shimo,T., St-Jacques,B., Iwamoto,M.,
            Enomoto-Iwamoto,M., Koyama,E. and Pacifici,M.
  TITLE     Indian and sonic hedgehogs regulate synchondrosis growth plate and
            cranial base development and function
  JOURNAL   Dev Biol 299 (1), 272-282 (2006)
   PUBMED   16935278
REFERENCE   7  (bases 1 to 375)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   8  (bases 1 to 375)
  AUTHORS   Wang,Z.F., Krasikov,T., Frey,M.R., Wang,J., Matera,A.G. and
            Marzluff,W.F.
  TITLE     Characterization of the mouse histone gene cluster on chromosome
            13: 45 histone genes in three patches spread over 1Mb
  JOURNAL   Genome Res 6 (8), 688-701 (1996)
   PUBMED   8858344
REFERENCE   9  (bases 1 to 375)
  AUTHORS   Drabent,B., Kardalinou,E., Bode,C. and Doenecke,D.
  TITLE     Association of histone H4 genes with the mammalian testis-specific
            H1t histone gene
  JOURNAL   DNA Cell Biol 14 (7), 591-597 (1995)
   PUBMED   7626218
REFERENCE   10 (bases 1 to 375)
  AUTHORS   Meier,V.S., Bohni,R. and Schumperli,D.
  TITLE     Nucleotide sequence of two mouse histone H4 genes
  JOURNAL   Nucleic Acids Res 17 (2), 795 (1989)
   PUBMED   2915930
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL592149.8.
            
            On Feb 21, 2014 this sequence version replaced NM_178208.1.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Two molecules of each of the four core histones (H2A,
            H2B, H3, and H4) form an octamer, around which approximately 146 bp
            of DNA is wrapped in repeating units, called nucleosomes. The
            linker histone, H1, interacts with linker DNA between nucleosomes
            and functions in the compaction of chromatin into higher order
            structures. This gene is intronless and encodes a
            replication-dependent histone that is a replication-dependent
            histone that is a member of the histone H4 family. Transcripts from
            this gene lack polyA tails but instead contain a palindromic
            termination element. [provided by RefSeq, Sep 2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BY227139.1, BY581463.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-375               AL592149.8         178499-178873       c
FEATURES             Location/Qualifiers
     source          1..375
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 9.88 cM"
     gene            1..375
                     /gene="H4c3"
                     /gene_synonym="H4c1; H4c11; H4c12; H4c14; H4c16; H4c2;
                     H4c4; H4c6; H4c8; H4c9; H4f16; Hist1h4c"
                     /note="H4 clustered histone 3"
                     /db_xref="GeneID:319155"
                     /db_xref="MGI:MGI:2448421"
     exon            1..375
                     /gene="H4c3"
                     /gene_synonym="H4c1; H4c11; H4c12; H4c14; H4c16; H4c2;
                     H4c4; H4c6; H4c8; H4c9; H4f16; Hist1h4c"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..321
                     /gene="H4c3"
                     /gene_synonym="H4c1; H4c11; H4c12; H4c14; H4c16; H4c2;
                     H4c4; H4c6; H4c8; H4c9; H4f16; Hist1h4c"
                     /note="histone 1, H4c; germinal histone H4; histone
                     cluster 1, H4c"
                     /codon_start=1
                     /product="histone H4"
                     /protein_id="NP_835515.1"
                     /db_xref="CCDS:CCDS26359.1"
                     /db_xref="GeneID:319155"
                     /db_xref="MGI:MGI:2448421"
                     /translation="MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGV
                     KRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG
                     G"
ORIGIN      
        1 gtcataacca tgtctggacg tggtaagggt ggtaaaggcc ttgggaaagg cggcgctaag
       61 cgccaccgta aggttctccg tgataacatc cagggcatta ccaagcccgc catccgccgc
      121 ctggcccggc gcgggggagt gaagcgcatc tccggcctca tctacgagga gacccgcggt
      181 gtgctgaagg tgttcctgga gaacgtgatc cgcgacgccg tcacctacac ggagcacgcc
      241 aagcgcaaga ccgtcaccgc catggacgtg gtctacgcgc tcaagcgcca gggccgcact
      301 ctctacggat tcggcggtta atcgactaac aaacgatttc cactgtcaac aaaaggccct
      361 tttcagggcc accca
//
