LOCUS       NM_175652                439 bp    mRNA    linear   ROD 07-MAY-2024
DEFINITION  Mus musculus H4 histone 16 (H4c16), mRNA.
ACCESSION   NM_175652 XM_976380
VERSION     NM_175652.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 439)
  AUTHORS   Zhang,X., He,H., Yu,H., Teng,X., Wang,Z., Li,C., Li,J., Yang,H.,
            Shen,J., Wu,T., Zhang,F., Zhang,Y. and Wu,Q.
  TITLE     Maternal RNA transcription in Dlk1-Dio3 domain is critical for
            proper development of the mouse placental vasculature
  JOURNAL   Commun Biol 7 (1), 363 (2024)
   PUBMED   38521877
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 439)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   3  (bases 1 to 439)
  AUTHORS   Li,L., Ghorbani,M., Weisz-Hubshman,M., Rousseau,J., Thiffault,I.,
            Schnur,R.E., Breen,C., Oegema,R., Weiss,M.M., Waisfisz,Q.,
            Welner,S., Kingston,H., Hills,J.A., Boon,E.M., Basel-Salmon,L.,
            Konen,O., Goldberg-Stern,H., Bazak,L., Tzur,S., Jin,J., Bi,X.,
            Bruccoleri,M., McWalter,K., Cho,M.T., Scarano,M., Schaefer,G.B.,
            Brooks,S.S., Hughes,S.S., van Gassen,K.L.I., van Hagen,J.M.,
            Pandita,T.K., Agrawal,P.B., Campeau,P.M. and Yang,X.J.
  TITLE     Lysine acetyltransferase 8 is involved in cerebral development and
            syndromic intellectual disability
  JOURNAL   J Clin Invest 130 (3), 1431-1445 (2020)
   PUBMED   31794431
REFERENCE   4  (bases 1 to 439)
  AUTHORS   Jung,E.M., Moffat,J.J., Liu,J., Dravid,S.M., Gurumurthy,C.B. and
            Kim,W.Y.
  TITLE     Arid1b haploinsufficiency disrupts cortical interneuron development
            and mouse behavior
  JOURNAL   Nat Neurosci 20 (12), 1694-1707 (2017)
   PUBMED   29184203
REFERENCE   5  (bases 1 to 439)
  AUTHORS   Mehta,A., Dobersch,S., Dammann,R.H., Bellusci,S., Ilinskaya,O.N.,
            Braun,T. and Barreto,G.
  TITLE     Validation of Tuba1a as appropriate internal control for
            normalization of gene expression analysis during mouse lung
            development
  JOURNAL   Int J Mol Sci 16 (3), 4492-4511 (2015)
   PUBMED   25723738
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 439)
  AUTHORS   Jackson,A., Kondilis,H.D., Khor,B., Sleckman,B.P. and Krangel,M.S.
  TITLE     Regulation of T cell receptor beta allelic exclusion at a level
            beyond accessibility
  JOURNAL   Nat Immunol 6 (2), 189-197 (2005)
   PUBMED   15640803
REFERENCE   7  (bases 1 to 439)
  AUTHORS   Thomson,S., Hollis,A., Hazzalin,C.A. and Mahadevan,L.C.
  TITLE     Distinct stimulus-specific histone modifications at hsp70 chromatin
            targeted by the transcription factor heat shock factor-1
  JOURNAL   Mol Cell 15 (4), 585-594 (2004)
   PUBMED   15327774
REFERENCE   8  (bases 1 to 439)
  AUTHORS   Pivot-Pajot,C., Caron,C., Govin,J., Vion,A., Rousseaux,S. and
            Khochbin,S.
  TITLE     Acetylation-dependent chromatin reorganization by BRDT, a
            testis-specific bromodomain-containing protein
  JOURNAL   Mol Cell Biol 23 (15), 5354-5365 (2003)
   PUBMED   12861021
REFERENCE   9  (bases 1 to 439)
  AUTHORS   Mulholland,N.M., Snyder,S.K., Kolla,S.S. and Smith,C.L.
  TITLE     Chromatin-dependent regulation of the MMTV promoter by cAMP
            signaling is mediated through distinct pathways
  JOURNAL   Exp Cell Res 287 (2), 361-373 (2003)
   PUBMED   12837291
  REMARK    GeneRIF: cAMP treatment results in a decrease in acetylation of
            Histh4.
REFERENCE   10 (bases 1 to 439)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC122804.4.
            
            On Mar 19, 2014 this sequence version replaced NM_175652.2.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Nucleosomes consist of approximately 146 bp of DNA
            wrapped around a histone octamer composed of pairs of each of the
            four core histones (H2A, H2B, H3, and H4). The chromatin fiber is
            further compacted through the interaction of a linker histone, H1,
            with the DNA between the nucleosomes to form higher order chromatin
            structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H4
            family. [provided by RefSeq, Aug 2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK045187.1, BY323001.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-439               AC122804.4         112852-113290
FEATURES             Location/Qualifiers
     source          1..439
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 66.72 cM"
     gene            1..439
                     /gene="H4c16"
                     /gene_synonym="B130044J01Rik; H4-16; H4c1; H4c11; H4c12;
                     H4c14; H4c2; H4c3; H4c4; H4c6; H4c8; H4c9; H4f16; Hist4h4"
                     /note="H4 histone 16"
                     /db_xref="GeneID:320332"
                     /db_xref="MGI:MGI:2448443"
     exon            1..439
                     /gene="H4c16"
                     /gene_synonym="B130044J01Rik; H4-16; H4c1; H4c11; H4c12;
                     H4c14; H4c2; H4c3; H4c4; H4c6; H4c8; H4c9; H4f16; Hist4h4"
                     /inference="alignment:Splign:2.1.0"
     CDS             53..364
                     /gene="H4c16"
                     /gene_synonym="B130044J01Rik; H4-16; H4c1; H4c11; H4c12;
                     H4c14; H4c2; H4c3; H4c4; H4c6; H4c8; H4c9; H4f16; Hist4h4"
                     /note="histone 4, H4; histone cluster 4, H4"
                     /codon_start=1
                     /product="histone H4"
                     /protein_id="NP_783583.1"
                     /db_xref="CCDS:CCDS39684.1"
                     /db_xref="GeneID:320332"
                     /db_xref="MGI:MGI:2448443"
                     /translation="MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGV
                     KRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG
                     G"
ORIGIN      
        1 ggcggcggat tactgtagtt tctcctgtct ctttattagg ttgtttacta atatgtcagg
       61 acgaggaaaa ggcggcaagg gtctggggaa aggtggcgcc aagcgacacc gcaaggttct
      121 ccgcgacaac atccagggca ttaccaagcc cgctatccgg cggttggctc ggcgtggcgg
      181 cgtgaagcgc atctcgggtc tcatctacga ggagactcgc ggtgtcctca aggttttcct
      241 tgagaatgtg atccgcgacg ccgtcaccta caccgagcac gccaagcgca agacggttac
      301 ggctatggac gtggtgtacg cgctcaagcg ccagggccgc actctgtacg gcttcggcgg
      361 ctaagcgagc cctcctgtgc ctaggccgtt cccttggccg gcttccccca tccacaaagg
      421 cccttttcag ggcccacaa
//
