LOCUS       NM_178210                423 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus H4 clustered histone 11 (H4c11), mRNA.
ACCESSION   NM_178210
VERSION     NM_178210.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 423)
  AUTHORS   Liu,L.J., Xie,R., Hussain,S., Lian,J.B., Rivera-Perez,J.,
            Jones,S.N., Stein,J.L., Stein,G.S. and van Wijnen,A.J.
  TITLE     Functional coupling of transcription factor HiNF-P and histone H4
            gene expression during pre- and post-natal mouse development
  JOURNAL   Gene 483 (1-2), 1-10 (2011)
   PUBMED   21605641
REFERENCE   2  (bases 1 to 423)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   3  (bases 1 to 423)
  AUTHORS   Wang,Z.F., Krasikov,T., Frey,M.R., Wang,J., Matera,A.G. and
            Marzluff,W.F.
  TITLE     Characterization of the mouse histone gene cluster on chromosome
            13: 45 histone genes in three patches spread over 1Mb
  JOURNAL   Genome Res 6 (8), 688-701 (1996)
   PUBMED   8858344
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL589651.8.
            
            On Aug 19, 2015 this sequence version replaced NM_178210.1.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Two molecules of each of the four core histones (H2A,
            H2B, H3, and H4) form an octamer, around which approximately 146 bp
            of DNA is wrapped in repeating units, called nucleosomes. The
            linker histone, H1, interacts with linker DNA between nucleosomes
            and functions in the compaction of chromatin into higher order
            structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H4
            family. Transcripts from this gene lack polyA tails but instead
            contain a palindromic termination element. [provided by RefSeq, Aug
            2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK010085.1, BY094021.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-423               AL589651.8         156024-156446
FEATURES             Location/Qualifiers
     source          1..423
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 7.94 cM"
     gene            1..423
                     /gene="H4c11"
                     /gene_synonym="H4c1; H4c12; H4c14; H4c16; H4c2; H4c3;
                     H4c4; H4c6; H4c8; H4c9; H4f16; Hist1h4j"
                     /note="H4 clustered histone 11"
                     /db_xref="GeneID:319159"
                     /db_xref="MGI:MGI:2448436"
     exon            1..423
                     /gene="H4c11"
                     /gene_synonym="H4c1; H4c12; H4c14; H4c16; H4c2; H4c3;
                     H4c4; H4c6; H4c8; H4c9; H4f16; Hist1h4j"
                     /inference="alignment:Splign:2.1.0"
     CDS             63..374
                     /gene="H4c11"
                     /gene_synonym="H4c1; H4c12; H4c14; H4c16; H4c2; H4c3;
                     H4c4; H4c6; H4c8; H4c9; H4f16; Hist1h4j"
                     /note="histone 1, H4j; histone cluster 1, H4j"
                     /codon_start=1
                     /product="histone H4"
                     /protein_id="NP_835582.1"
                     /db_xref="CCDS:CCDS26291.1"
                     /db_xref="GeneID:319159"
                     /db_xref="MGI:MGI:2448436"
                     /translation="MSGRGKGGKGLGKGGAKRHRKVLRDNIQGITKPAIRRLARRGGV
                     KRISGLIYEETRGVLKVFLENVIRDAVTYTEHAKRKTVTAMDVVYALKRQGRTLYGFG
                     G"
ORIGIN      
        1 taaaaagacg gcgctcaggc tcccggtcag catctctgtt ctgagctgtc ctgagtgcag
       61 tcatgtctgg cagaggtaag ggcgggaaag ggctcggtaa aggtggcgct aagcgccacc
      121 gcaaagtgct gcgcgacaac atccagggca tcacgaagcc cgccatccgc cgcctggccc
      181 ggcgcggggg agtgaagcgc atctccggcc tcatctacga ggagacccgc ggtgtgctga
      241 aggtgttcct ggagaacgtg atccgcgacg ccgtcaccta cacggagcac gccaagcgca
      301 agaccgtcac cgccatggac gtggtctacg cgctcaagcg ccagggccgc accctctacg
      361 ggttcggcgg ctaagctgct cgcttacact atatttccct aaaggtcctt ttcaggacca
      421 cca
//
