LOCUS       NM_001370931            1037 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus H3 histone, family 3C (H3f3c), mRNA.
ACCESSION   NM_001370931
VERSION     NM_001370931.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1037)
  AUTHORS   Xia,W. and Jiao,J.
  TITLE     Histone variant H3.3 orchestrates neural stem cell differentiation
            in the developing brain
  JOURNAL   Cell Death Differ 24 (9), 1548-1563 (2017)
   PUBMED   28524856
REFERENCE   2  (bases 1 to 1037)
  AUTHORS   Maehara,K., Harada,A., Sato,Y., Matsumoto,M., Nakayama,K.I.,
            Kimura,H. and Ohkawa,Y.
  TITLE     Tissue-specific expression of histone H3 variants diversified after
            species separation
  JOURNAL   Epigenetics Chromatin 8, 35 (2015)
   PUBMED   26388943
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1037)
  AUTHORS   Jermann,P., Hoerner,L., Burger,L. and Schubeler,D.
  TITLE     Short sequences can efficiently recruit histone H3 lysine 27
            trimethylation in the absence of enhancer activity and DNA
            methylation
  JOURNAL   Proc Natl Acad Sci U S A 111 (33), E3415-E3421 (2014)
   PUBMED   25092339
REFERENCE   4  (bases 1 to 1037)
  AUTHORS   Maze,I., Noh,K.M., Soshnev,A.A. and Allis,C.D.
  TITLE     Every amino acid matters: essential contributions of histone
            variants to mammalian development and disease
  JOURNAL   Nat Rev Genet 15 (4), 259-271 (2014)
   PUBMED   24614311
  REMARK    Review article
REFERENCE   5  (bases 1 to 1037)
  AUTHORS   Song,T.Y., Yang,J.H., Park,J.Y., Song,Y., Han,J.W., Youn,H.D. and
            Cho,E.J.
  TITLE     The role of histone chaperones in osteoblastic differentiation of
            C2C12 myoblasts
  JOURNAL   Biochem Biophys Res Commun 423 (4), 726-732 (2012)
   PUBMED   22705305
REFERENCE   6  (bases 1 to 1037)
  AUTHORS   Santenard,A., Ziegler-Birling,C., Koch,M., Tora,L., Bannister,A.J.
            and Torres-Padilla,M.E.
  TITLE     Heterochromatin formation in the mouse embryo requires critical
            residues of the histone variant H3.3
  JOURNAL   Nat Cell Biol 12 (9), 853-862 (2010)
   PUBMED   20676102
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL844536.13.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BU936190.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1037              AL844536.13        126754-127790       c
FEATURES             Location/Qualifiers
     source          1..1037
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="2"
                     /map="2 59.97 cM"
     gene            1..1037
                     /gene="H3f3c"
                     /gene_synonym="Gm14384; H3-5; H3mm11"
                     /note="H3 histone, family 3C"
                     /db_xref="GeneID:625328"
                     /db_xref="MGI:MGI:3650546"
     exon            1..1037
                     /gene="H3f3c"
                     /gene_synonym="Gm14384; H3-5; H3mm11"
                     /inference="alignment:Splign:2.1.0"
     CDS             117..527
                     /gene="H3f3c"
                     /gene_synonym="Gm14384; H3-5; H3mm11"
                     /note="embryonic"
                     /codon_start=1
                     /product="histone H3.3C"
                     /protein_id="NP_001357860.1"
                     /db_xref="GeneID:625328"
                     /db_xref="MGI:MGI:3650546"
                     /translation="MALTKQTARKSTGGKAPRKQLATKATRKSAPSTGGVKKPHRYRP
                     GTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSAAIGALQEASEAYLV
                     GLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA"
     regulatory      805..810
                     /regulatory_class="polyA_signal_sequence"
                     /gene="H3f3c"
                     /gene_synonym="Gm14384; H3-5; H3mm11"
                     /note="hexamer: AATAAA"
     polyA_site      829
                     /gene="H3f3c"
                     /gene_synonym="Gm14384; H3-5; H3mm11"
     regulatory      1018..1023
                     /regulatory_class="polyA_signal_sequence"
                     /gene="H3f3c"
                     /gene_synonym="Gm14384; H3-5; H3mm11"
                     /note="hexamer: ATTAAA"
     polyA_site      1037
                     /gene="H3f3c"
                     /gene_synonym="Gm14384; H3-5; H3mm11"
                     /note="major polyA site"
ORIGIN      
        1 gaattgtgtt cgcagccttc gccgcgccgc cgccgctctc caacgccagc gccgcctctc
       61 ccttgccgag ctccagccga aggagaaggg ggggtaagta aggaggtgtc cataccatgg
      121 ctcttacaaa gcagactgcc cgcaaatcca ccggtggtaa agcacccagg aaacaactgg
      181 ctacaaaagc cactcgcaag agtgcgccct ctactggagg ggtgaagaaa cctcatcgtt
      241 acaggcctgg cactgtggca ctccgtgaaa tcagacgcta tcagaagtcc actgaacttc
      301 tgatccgcaa gctccccttt cagcgtctgg tgcgagaaat tgctcaggac ttcaaaacag
      361 atctgcgctt ccagagtgca gctattggtg ctttgcagga ggcaagtgag gcctatctgg
      421 ttggcctttt tgaagatacc aatctgtgtg ctatccatgc caaacgtgta acaattatgc
      481 caaaagatat ccagctagca cgccgcatac gcggagaacg tgcttaagag tccactatga
      541 ggggaaacat ttcattctca aaaaaatttt tttcctcttc ttcctgttat cagtagttct
      601 gaatattaga tattttttcc atggggtcaa aggtacctaa gtatatgatt gcgagtggaa
      661 acatagggga cagaatcagg tattggcgtt tctccatgtt catttgtgtg tgaattttta
      721 atataaatgc aagatgtaaa gcattaatgg aagcaaaatg tttcagtgaa cacatttcaa
      781 gagttcaact ttataacaat tataaataaa cctgttaaaa ttttctggac aatgccagca
      841 tttggatttt ttaaaaataa gtaaatttct tattgacagc aactaaatgg tgtttgtagc
      901 atttttatca cacagtagat tccatccatt cactatactt ttctaactga gttgtcctac
      961 atacaagtac atgtttttaa tgttgtcagt cttgtgtgct gttcctgtaa gtttgctatt
     1021 aaaatacatt aaactat
//
