LOCUS       NM_178216                664 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus H3 clustered histone 14 (H3c14), mRNA.
ACCESSION   NM_178216 NM_019469 XM_619936
VERSION     NM_178216.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 664)
  AUTHORS   Vetrivel,S., Truong,D.J., Wurst,W., Graw,J. and Giesert,F.
  TITLE     Identification of ocular regulatory functions of core histone
            variant H3.2
  JOURNAL   Exp Eye Res 226, 109346 (2023)
   PUBMED   36529279
  REMARK    GeneRIF: Identification of ocular regulatory functions of core
            histone variant H3.2.
REFERENCE   2  (bases 1 to 664)
  AUTHORS   Vetrivel,S., Tiso,N., Kugler,A., Irmler,M., Horsch,M., Beckers,J.,
            Hladik,D., Giesert,F., Gailus-Durner,V., Fuchs,H., Sabrautzki,S.,
            Hrabe de Angelis,M. and Graw,J.
  TITLE     Mutation in the mouse histone gene Hist2h3c1 leads to degeneration
            of the lens vesicle and severe microphthalmia
  JOURNAL   Exp Eye Res 188, 107632 (2019)
   PUBMED   30991053
REFERENCE   3  (bases 1 to 664)
  AUTHORS   Bird,A.D., Flecknoe,S.J., Tan,K.H., Olsson,P.F., Antony,N.,
            Mantamadiotis,T., Mollard,R., Hooper,S.B. and Cole,T.J.
  TITLE     cAMP response element binding protein is required for
            differentiation of respiratory epithelium during murine development
  JOURNAL   PLoS One 6 (3), e17843 (2011)
   PUBMED   21408140
  REMARK    Erratum:[PLoS One. 2012;7(1).
            doi:10.1371/annotation/ec04ad74-63cc-4fbe-9ad8-074a1d62fdf4.
            Mollard, Richard [added]]
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 664)
  AUTHORS   Quille,M.L., Carat,S., Quemener-Redon,S., Hirchaud,E., Baron,D.,
            Benech,C., Guihot,J., Placet,M., Mignen,O., Ferec,C., Houlgatte,R.
            and Friocourt,G.
  TITLE     High-throughput analysis of promoter occupancy reveals new targets
            for Arx, a gene mutated in mental retardation and
            interneuronopathies
  JOURNAL   PLoS One 6 (9), e25181 (2011)
   PUBMED   21966449
REFERENCE   5  (bases 1 to 664)
  AUTHORS   Ezhkova,E., Pasolli,H.A., Parker,J.S., Stokes,N., Su,I.H.,
            Hannon,G., Tarakhovsky,A. and Fuchs,E.
  TITLE     Ezh2 orchestrates gene expression for the stepwise differentiation
            of tissue-specific stem cells
  JOURNAL   Cell 136 (6), 1122-1135 (2009)
   PUBMED   19303854
REFERENCE   6  (bases 1 to 664)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   7  (bases 1 to 664)
  AUTHORS   Gruber,A., Streit,A., Reist,M., Benninger,P., Bohni,R. and
            Schumperli,D.
  TITLE     Structure of a mouse histone-encoding gene cluster
  JOURNAL   Gene 95 (2), 303-304 (1990)
   PUBMED   2249786
REFERENCE   8  (bases 1 to 664)
  AUTHORS   Hurt,M.M., Chodchoy,N. and Marzluff,W.F.
  TITLE     The mouse histone H2a.2 gene from chromosome 3
  JOURNAL   Nucleic Acids Res 17 (21), 8876 (1989)
   PUBMED   2587235
REFERENCE   9  (bases 1 to 664)
  AUTHORS   Seldin,M.F. and Steinberg,A.D.
  TITLE     Human histone 3 F2 detects RFLPs in inbred mice, cosegregates with
            H4F2 and does not map to possible syntenic groups on mouse distal
            chromosomes 1 and distal chromosomes 3
  JOURNAL   Nucleic Acids Res 15 (14), 5900 (1987)
   PUBMED   2886976
REFERENCE   10 (bases 1 to 664)
  AUTHORS   Taylor,J.D., Wellman,S.E. and Marzluff,W.F.
  TITLE     Sequences of four mouse histone H3 genes: implications for
            evolution of mouse histone genes
  JOURNAL   J Mol Evol 23 (3), 242-249 (1986)
   PUBMED   3027355
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC125099.3.
            
            [WARNING] On Jan 31, 2025 this sequence was replaced by
            NM_178216.4.
            
            On Mar 12, 2014 this sequence version replaced NM_178216.2.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. This structure consists of approximately 146 bp of DNA
            wrapped around a nucleosome, an octamer composed of pairs of each
            of the four core histones (H2A, H2B, H3, and H4). The chromatin
            fiber is further compacted through the interaction of a linker
            histone, H1, with the DNA between the nucleosomes to form higher
            order chromatin structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H3
            family. [provided by RefSeq, Aug 2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC094041.1, FO709345.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            CDS uses downstream in-frame AUG :: upstream AUG and CDS extension
                                                is not conserved
            RefSeq Select criteria           :: based on single protein-coding
                                                transcript
            replication-dependent histone    :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-664               AC125099.3         28706-29369         c
FEATURES             Location/Qualifiers
     source          1..664
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 41.69 cM"
     gene            1..664
                     /gene="H3c14"
                     /gene_synonym="H3-615; H3c13; H3c15; H3c2; H3c3; H3c4;
                     H3c6; H3c7; H3f2; Hist2h3c1; Hist2h3ca1"
                     /note="H3 clustered histone 14"
                     /db_xref="GeneID:15077"
                     /db_xref="MGI:MGI:2448355"
     exon            1..664
                     /gene="H3c14"
                     /gene_synonym="H3-615; H3c13; H3c15; H3c2; H3c3; H3c4;
                     H3c6; H3c7; H3f2; Hist2h3c1; Hist2h3ca1"
                     /inference="alignment:Splign:2.1.0"
     CDS             202..612
                     /gene="H3c14"
                     /gene_synonym="H3-615; H3c13; H3c15; H3c2; H3c3; H3c4;
                     H3c6; H3c7; H3f2; Hist2h3c1; Hist2h3ca1"
                     /note="histone 2, H3c1; H3 histone, family 2; histone 2,
                     H3ca1; histone cluster 2, H3c1; H3-clustered histone 2;
                     H3-clustered histone 3; H3-clustered histone 4;
                     H3-clustered histone 6; H3-clustered histone 7;
                     H3-clustered histone 13; H3-clustered histone 15"
                     /codon_start=1
                     /product="histone H3.2"
                     /protein_id="NP_835734.2"
                     /db_xref="CCDS:CCDS38554.2"
                     /db_xref="GeneID:15077"
                     /db_xref="MGI:MGI:2448355"
                     /translation="MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRP
                     GTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLV
                     GLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA"
ORIGIN      
        1 ggcgggtcag gtggcgtggc gggcccgagc caatgggcga ggtcggggcc ggtgacgcca
       61 cggccaatgg cgcggcagcg cgggagtttc aagtcgctgt ctccgccccg ccgcggggaa
      121 gactgcgcct ataaaggcgg ccggctcggg ccggtatcag gtccccgagt gctcctcgtt
      181 tgggtgtctt ccgtcttcgc catggcccgt acgaagcaga ctgcccgcaa gtccaccggc
      241 ggcaaggccc cgcgcaagca gctggccacc aaggccgccc gcaagagcgc cccggccacg
      301 ggcggcgtga agaagccgca ccgctaccgg cccggcaccg tggcgctgcg ggagatccgg
      361 cgctaccaga agtcgaccga gctgctgatc cgcaagctgc cgttccagcg cctggtgcgc
      421 gagatcgcgc aggacttcaa gacggacctg cgcttccaga gctcggccgt catggcgctg
      481 caggaggcga gcgaggccta cctggtgggg ctgttcgagg acaccaacct gtgcgccatc
      541 cacgccaaac gcgtcaccat catgcccaag gacatccagt tggcccgccg catccgtggg
      601 gagcgcgctt aagcgccctg tctcccatcc attccccaca aaggctcttt tcagagccac
      661 caca
//
