LOCUS       NM_178215                502 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus H3 clustered histone 13 (H3c13), mRNA.
ACCESSION   NM_178215 XM_906315
VERSION     NM_178215.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 502)
  AUTHORS   Vetrivel,S., Truong,D.J., Wurst,W., Graw,J. and Giesert,F.
  TITLE     Identification of ocular regulatory functions of core histone
            variant H3.2
  JOURNAL   Exp Eye Res 226, 109346 (2023)
   PUBMED   36529279
REFERENCE   2  (bases 1 to 502)
  AUTHORS   Vetrivel,S., Tiso,N., Kugler,A., Irmler,M., Horsch,M., Beckers,J.,
            Hladik,D., Giesert,F., Gailus-Durner,V., Fuchs,H., Sabrautzki,S.,
            Hrabe de Angelis,M. and Graw,J.
  TITLE     Mutation in the mouse histone gene Hist2h3c1 leads to degeneration
            of the lens vesicle and severe microphthalmia
  JOURNAL   Exp Eye Res 188, 107632 (2019)
   PUBMED   30991053
REFERENCE   3  (bases 1 to 502)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   4  (bases 1 to 502)
  AUTHORS   Wang,Z.F., Tisovec,R., Debry,R.W., Frey,M.R., Matera,A.G. and
            Marzluff,W.F.
  TITLE     Characterization of the 55-kb mouse histone gene cluster on
            chromosome 3
  JOURNAL   Genome Res 6 (8), 702-714 (1996)
   PUBMED   8858345
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AC125099.3.
            
            On Mar 12, 2014 this sequence version replaced NM_178215.1.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. This structure consists of approximately 146 bp of DNA
            wrapped around a nucleosome, an octamer composed of pairs of each
            of the four core histones (H2A, H2B, H3, and H4). The chromatin
            fiber is further compacted through the interaction of a linker
            histone, H1, with the DNA between the nucleosomes to form higher
            order chromatin structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H3
            family. [provided by RefSeq, Aug 2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC139252.1, SRR7345562.2153946.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-502               AC125099.3         6899-7400           c
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="3"
                     /map="3 41.71 cM"
     gene            1..502
                     /gene="H3c13"
                     /gene_synonym="H3-615; H3-616; H3c14; H3c15; H3c2; H3c3;
                     H3c4; H3c6; H3c7; Hist2h3b"
                     /note="H3 clustered histone 13"
                     /db_xref="GeneID:319154"
                     /db_xref="MGI:MGI:2448351"
     exon            1..502
                     /gene="H3c13"
                     /gene_synonym="H3-615; H3-616; H3c14; H3c15; H3c2; H3c3;
                     H3c4; H3c6; H3c7; Hist2h3b"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..451
                     /gene="H3c13"
                     /gene_synonym="H3-615; H3-616; H3c14; H3c15; H3c2; H3c3;
                     H3c4; H3c6; H3c7; Hist2h3b"
                     /note="histone protein Hist2h2bb; histone cluster 2, H3b;
                     H3-clustered histone 2; H3-clustered histone 3;
                     H3-clustered histone 4; H3-clustered histone 6;
                     H3-clustered histone 7; H3-clustered histone 14;
                     H3-clustered histone 15"
                     /codon_start=1
                     /product="histone H3.2"
                     /protein_id="NP_835587.1"
                     /db_xref="CCDS:CCDS17638.1"
                     /db_xref="GeneID:319154"
                     /db_xref="MGI:MGI:2448351"
                     /translation="MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRP
                     GTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEASEAYLV
                     GLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA"
     polyA_site      502
                     /gene="H3c13"
                     /gene_synonym="H3-615; H3-616; H3c14; H3c15; H3c2; H3c3;
                     H3c4; H3c6; H3c7; Hist2h3b"
                     /note="major polyA site"
ORIGIN      
        1 gtatggccac ttggcgtctg caagccgaag tcgcaaaaat atggcccgta cgaagcagac
       61 cgcccgcaag tccaccggcg gcaaggcccc gcgcaagcag ctggccacca aggccgcccg
      121 caagagcgcc ccggccacgg gcggcgtgaa gaagccgcac cgctaccggc ccggcaccgt
      181 ggcgctgcgg gagatccggc gctaccagaa gtcgaccgag ctgctgatcc gcaagctgcc
      241 gttccagcgc ctggtgcgcg agatcgcgca ggacttcaag acggacctgc gcttccagag
      301 ctcggccgtc atggcgctgc aggaggcgag cgaggcctac ctggtggggc tgttcgagga
      361 caccaacctg tgcgccatcc acgccaaacg cgtcaccatc atgcccaagg acatccagtt
      421 ggcccgccgc atccgtgggg agcgcgctta agcgccctgt ttcccttcca tcccccacaa
      481 aggctctttt cagagccacc ta
//
