LOCUS       NM_013550                502 bp    mRNA    linear   ROD 07-FEB-2025
DEFINITION  Mus musculus H3 clustered histone 1 (H3c1), mRNA.
ACCESSION   NM_013550 NM_021711
VERSION     NM_013550.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 502)
  AUTHORS   Zhang,Y., Jiang,H., Dong,M., Min,J., He,X., Tan,Y., Liu,F.,
            Chen,M., Chen,X., Yin,Q., Zheng,L., Shao,Y., Li,X. and Chen,H.
  TITLE     Macrophage MCT4 inhibition activates reparative genes and protects
            from atherosclerosis by histone H3 lysine 18 lactylation
  JOURNAL   Cell Rep 43 (5), 114180 (2024)
   PUBMED   38733581
  REMARK    GeneRIF: Macrophage MCT4 inhibition activates reparative genes and
            protects from atherosclerosis by histone H3 lysine 18 lactylation.
            Erratum:[Cell Rep. 2024 Oct 22;43(10):114884. doi:
            10.1016/j.celrep.2024.114884.. PMID: 39392757]
REFERENCE   2  (bases 1 to 502)
  AUTHORS   Tsuji-Hosokawa,A., Kashimada,K., Kato,T., Ogawa,Y., Nomura,R.,
            Takasawa,K., Lavery,R., Coschiera,A., Schlessinger,D., Harley,V.R.,
            Takada,S. and Morio,T.
  TITLE     Peptidyl arginine deiminase 2 (Padi2) is expressed in Sertoli cells
            in a specific manner and regulated by SOX9 during testicular
            development
  JOURNAL   Sci Rep 8 (1), 13263 (2018)
   PUBMED   30185873
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 502)
  AUTHORS   Fang,J., Cheng,J., Wang,J., Zhang,Q., Liu,M., Gong,R., Wang,P.,
            Zhang,X., Feng,Y., Lan,W., Gong,Z., Tang,C., Wong,J., Yang,H.,
            Cao,C. and Xu,Y.
  TITLE     Hemi-methylated DNA opens a closed conformation of UHRF1 to
            facilitate its histone recognition
  JOURNAL   Nat Commun 7, 11197 (2016)
   PUBMED   27045799
  REMARK    GeneRIF: Hemi-methylated DNA opens a closed conformation of UHRF1
            to facilitate its H3 histone recognition.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 502)
  AUTHORS   Tang,M.C., Jacobs,S.A., Mattiske,D.M., Soh,Y.M., Graham,A.N.,
            Tran,A., Lim,S.L., Hudson,D.F., Kalitsis,P., O'Bryan,M.K.,
            Wong,L.H. and Mann,J.R.
  TITLE     Contribution of the two genes encoding histone variant h3.3 to
            viability and fertility in mice
  JOURNAL   PLoS Genet 11 (2), e1004964 (2015)
   PUBMED   25675407
  REMARK    Publication Status: Online-Only
REFERENCE   5  (bases 1 to 502)
  AUTHORS   Harada,A., Maehara,K., Sato,Y., Konno,D., Tachibana,T., Kimura,H.
            and Ohkawa,Y.
  TITLE     Incorporation of histone H3.1 suppresses the lineage potential of
            skeletal muscle
  JOURNAL   Nucleic Acids Res 43 (2), 775-786 (2015)
   PUBMED   25539924
REFERENCE   6  (bases 1 to 502)
  AUTHORS   Abdallah,B.M., Ditzel,N., Mahmood,A., Isa,A., Traustadottir,G.A.,
            Schilling,A.F., Ruiz-Hidalgo,M.J., Laborda,J., Amling,M. and
            Kassem,M.
  TITLE     DLK1 is a novel regulator of bone mass that mediates estrogen
            deficiency-induced bone loss in mice
  JOURNAL   J Bone Miner Res 26 (7), 1457-1471 (2011)
   PUBMED   21308776
REFERENCE   7  (bases 1 to 502)
  AUTHORS   Lewis,A., Mitsuya,K., Umlauf,D., Smith,P., Dean,W., Walter,J.,
            Higgins,M., Feil,R. and Reik,W.
  TITLE     Imprinting on distal chromosome 7 in the placenta involves
            repressive histone methylation independent of DNA methylation
  JOURNAL   Nat Genet 36 (12), 1291-1295 (2004)
   PUBMED   15516931
REFERENCE   8  (bases 1 to 502)
  AUTHORS   Govin,J., Caron,C., Lestrat,C., Rousseaux,S. and Khochbin,S.
  TITLE     The role of histones in chromatin remodelling during mammalian
            spermiogenesis
  JOURNAL   Eur J Biochem 271 (17), 3459-3469 (2004)
   PUBMED   15317581
  REMARK    Review article
REFERENCE   9  (bases 1 to 502)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   10 (bases 1 to 502)
  AUTHORS   Chen,D., Ma,H., Hong,H., Koh,S.S., Huang,S.M., Schurter,B.T.,
            Aswad,D.W. and Stallcup,M.R.
  TITLE     Regulation of transcription by a protein methyltransferase
  JOURNAL   Science 284 (5423), 2174-2177 (1999)
   PUBMED   10381882
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL590388.4.
            
            On Feb 22, 2014 this sequence version replaced NM_013550.4.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. This structure consists of approximately 146 bp of DNA
            wrapped around a nucleosome, an octamer composed of pairs of each
            of the four core histones (H2A, H2B, H3, and H4). The chromatin
            fiber is further compacted through the interaction of a linker
            histone, H1, with the DNA between the nucleosomes to form higher
            order chromatin structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H3
            family. Transcripts from this gene lack polyA tails; instead, they
            contain a palindromic termination element. [provided by RefSeq, Aug
            2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: CO427605.1, AK018952.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-502               AL590388.4         125992-126493
FEATURES             Location/Qualifiers
     source          1..502
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 9.91 cM"
     gene            1..502
                     /gene="H3c1"
                     /gene_synonym="H3c10; H3c11; H3c8; Hist1h3a"
                     /note="H3 clustered histone 1"
                     /db_xref="GeneID:360198"
                     /db_xref="MGI:MGI:2668828"
     exon            1..502
                     /gene="H3c1"
                     /gene_synonym="H3c10; H3c11; H3c8; Hist1h3a"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..444
                     /gene="H3c1"
                     /gene_synonym="H3c10; H3c11; H3c8; Hist1h3a"
                     /note="histone 1, H3a; histone cluster 1, H3a"
                     /codon_start=1
                     /product="histone H3.1"
                     /protein_id="NP_038578.2"
                     /db_xref="CCDS:CCDS26368.1"
                     /db_xref="GeneID:360198"
                     /db_xref="MGI:MGI:2668828"
                     /translation="MARTKQTARKSTGGKAPRKQLATKAARKSAPATGGVKKPHRYRP
                     GTVALREIRRYQKSTELLIRKLPFQRLVREIAQDFKTDLRFQSSAVMALQEACEAYLV
                     GLFEDTNLCAIHAKRVTIMPKDIQLARRIRGERA"
     polyA_site      502
                     /gene="H3c1"
                     /gene_synonym="H3c10; H3c11; H3c8; Hist1h3a"
                     /note="major polyA site"
ORIGIN      
        1 aagtgctcac cagcttgctt tctagttttt gctatggctc gtactaagca gaccgctcgc
       61 aagtccaccg gcggcaaggc cccgcgcaag cagctagcca ccaaagccgc ccgcaagagc
      121 gccccggcca ccggcggcgt gaagaagcct caccgctacc gtcccggcac cgtggcgctg
      181 cgcgagatcc ggcgctacca gaagtcgacc gagctgctga tccgcaagct gccgttccag
      241 cgcctggtgc gcgagatcgc gcaggacttc aagaccgacc tgcgcttcca gagctcggcc
      301 gtcatggctc tgcaggaggc ctgtgaggcc taccttgtgg gtctgtttga ggacaccaac
      361 ctgtgcgcca tccacgccaa gcgtgtcacc atcatgccca aggacatcca actggcccgc
      421 cgcatccgcg gggagagggc gtaattgtac agttccgtac agttctacgg aattaaccaa
      481 aggctctttt cagagccaca ca
//
