LOCUS       NM_027067               1049 bp    mRNA    linear   ROD 04-AUG-2023
DEFINITION  Mus musculus H2B.W histone 2 (H2bw2), mRNA.
ACCESSION   NM_027067 XM_486774 XM_906752
VERSION     NM_027067.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1049)
  AUTHORS   Gonzalez-Romero R, Rivera-Casas C, Ausio J, Mendez J and
            Eirin-Lopez JM.
  TITLE     Birth-and-death long-term evolution promotes histone H2B variant
            diversification in the male germinal cell line
  JOURNAL   Mol Biol Evol 27 (8), 1802-1812 (2010)
   PUBMED   20194426
REFERENCE   2  (bases 1 to 1049)
  AUTHORS   Govin J, Escoffier E, Rousseaux S, Kuhn L, Ferro M, Thevenon J,
            Catena R, Davidson I, Garin J, Khochbin S and Caron C.
  TITLE     Pericentric heterochromatin reprogramming by new histone variants
            during mouse spermiogenesis
  JOURNAL   J Cell Biol 176 (3), 283-294 (2007)
   PUBMED   17261847
REFERENCE   3  (bases 1 to 1049)
  AUTHORS   McManus EJ, Sakamoto K, Armit LJ, Ronaldson L, Shpiro N, Marquez R
            and Alessi DR.
  TITLE     Role that phosphorylation of GSK3 plays in insulin and Wnt
            signalling defined by knockin analysis
  JOURNAL   EMBO J 24 (8), 1571-1583 (2005)
   PUBMED   15791206
  REMARK    GeneRIF: Data show that in glycogen synthase kinase
            (GSK)3alpha/GSK3beta homozygous knockin cells, Wnt3a induces normal
            inactivation of GSK3.
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AK005982.1 and BC117076.1.
            
            On Apr 9, 2011 this sequence version replaced NM_027067.1.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Two molecules of each of the four core histones (H2A,
            H2B, H3, and H4) form an octamer, around which approximately 146 bp
            of DNA is wrapped in repeating units, called nucleosomes. The
            linker histone, H1, interacts with linker DNA between nucleosomes
            and functions in the compaction of chromatin into higher order
            structures. This gene encodes a replication-independent histone
            that is a member of the H2B histone family. [provided by RefSeq,
            Nov 2015].
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK005982.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria          :: based on single protein-coding
                                               transcript
            replication-independent histone :: PMID: 17261847
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-951               AK005982.1         2-952
            952-991             BC117076.1         943-982
            992-1049            AK005982.1         993-1050
FEATURES             Location/Qualifiers
     source          1..1049
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="X"
                     /map="X 59.1 cM"
     gene            1..1049
                     /gene="H2bw2"
                     /gene_synonym="1700014N06Rik; H2bfm; H2bfw; H2bl2"
                     /note="H2B.W histone 2"
                     /db_xref="GeneID:69389"
                     /db_xref="MGI:MGI:1916639"
     exon            1..1049
                     /gene="H2bw2"
                     /gene_synonym="1700014N06Rik; H2bfm; H2bfw; H2bl2"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1027..1032
                     /regulatory_class="polyA_signal_sequence"
                     /gene="H2bw2"
                     /gene_synonym="1700014N06Rik; H2bfm; H2bfw; H2bl2"
ORIGIN      
        1 gccattttct gactttccgt caggttggcg ccctcagcca tggcgtctac cacggctatg
       61 gacgttctgg aggagctatc ttcggatagt tccgaaaaac aggtacaacc aagaaagcct
      121 gagaaagcta aaagggaaaa ggacaaacca aagaaagggg ggccggagaa gaaggccaag
      181 aaagagaaac aggagaaagc aaagccggag aaaaagccga agaagaagcc agagaaagag
      241 aagccggagg gagagaagct ggagaagaaa cccaagaaag acaagcggga gaaagcgaag
      301 ccgaagaaga agcccgagca agagaaccgt gagcaagaga ctcctgagca ggagaagcct
      361 gaggtgcagc ggcgtcgctc acttcaccaa agcatcaggg aagatgagcg tagagcccgt
      421 ctgatcagac gccgtaagaa cagcttcgct atctactttc cgaaggtgct gaaaaatatc
      481 cacgtgggtc tctccctctc gcagcggtct gtgaacatcc tggattcatt cgtgaaggat
      541 atgtttgaaa gaattgcatc cgaagccagc ttcttggcgc gtcaagccag aaactctact
      601 atcaactcca gagagatcca gaccgctatt cgacttctgc ttcctggcga gctctgccgg
      661 cgtgcagtgg ctgaaggaac catggcgatg gtccggtata tctccaacaa gtaagcagct
      721 ttaatgtcaa aacaacaaaa cccaaaggct cttttcagag ccaccacttc tcctaagaga
      781 gctgtagcat gaacaactcc agcaaaagag tgactttgac tttaaaccaa acaaaactca
      841 aaggctcttt tcagagccac cacttctcct aagagagctg tagcaggaat atctccagca
      901 aatgagtgac tttgacttta aaccaaacaa aatccaaagg ctcttttaga gccaccactt
      961 cgtggttcga gtttgaaccc cagaagcctc cggccccttc ttcgggcatt cccgattaac
     1021 ttaaaaaata aaatgttgtt tgttatact
//
