LOCUS       NM_178196                464 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus H2B clustered histone 8 (H2bc8), mRNA.
ACCESSION   NM_178196
VERSION     NM_178196.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 464)
  AUTHORS   Miller,J.A., Nathanson,J., Franjic,D., Shim,S., Dalley,R.A.,
            Shapouri,S., Smith,K.A., Sunkin,S.M., Bernard,A., Bennett,J.L.,
            Lee,C.K., Hawrylycz,M.J., Jones,A.R., Amaral,D.G., Sestan,N.,
            Gage,F.H. and Lein,E.S.
  TITLE     Conserved molecular signatures of neurogenesis in the hippocampal
            subgranular zone of rodents and primates
  JOURNAL   Development 140 (22), 4633-4644 (2013)
   PUBMED   24154525
REFERENCE   2  (bases 1 to 464)
  AUTHORS   Xu,Y., Wang,Y., Besnard,V., Ikegami,M., Wert,S.E., Heffner,C.,
            Murray,S.A., Donahue,L.R. and Whitsett,J.A.
  TITLE     Transcriptional programs controlling perinatal lung maturation
  JOURNAL   PLoS One 7 (8), e37046 (2012)
   PUBMED   22916088
REFERENCE   3  (bases 1 to 464)
  AUTHORS   Ballif,B.A., Carey,G.R., Sunyaev,S.R. and Gygi,S.P.
  TITLE     Large-scale identification and evolution indexing of tyrosine
            phosphorylation sites from murine brain
  JOURNAL   J Proteome Res 7 (1), 311-318 (2008)
   PUBMED   18034455
REFERENCE   4  (bases 1 to 464)
  AUTHORS   Das,R., Burke,T. and Plow,E.F.
  TITLE     Histone H2B as a functionally important plasminogen receptor on
            macrophages
  JOURNAL   Blood 110 (10), 3763-3772 (2007)
   PUBMED   17690254
REFERENCE   5  (bases 1 to 464)
  AUTHORS   Odegard,V.H., Kim,S.T., Anderson,S.M., Shlomchik,M.J. and
            Schatz,D.G.
  TITLE     Histone modifications associated with somatic hypermutation
  JOURNAL   Immunity 23 (1), 101-110 (2005)
   PUBMED   16039583
REFERENCE   6  (bases 1 to 464)
  AUTHORS   Fernandez-Capetillo,O., Allis,C.D. and Nussenzweig,A.
  TITLE     Phosphorylation of histone H2B at DNA double-strand breaks
  JOURNAL   J Exp Med 199 (12), 1671-1677 (2004)
   PUBMED   15197225
REFERENCE   7  (bases 1 to 464)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   8  (bases 1 to 464)
  AUTHORS   Wang,Z.F., Tisovec,R., Debry,R.W., Frey,M.R., Matera,A.G. and
            Marzluff,W.F.
  TITLE     Characterization of the 55-kb mouse histone gene cluster on
            chromosome 3
  JOURNAL   Genome Res 6 (8), 702-714 (1996)
   PUBMED   8858345
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL592149.8.
            
            On Feb 26, 2014 this sequence version replaced NM_178196.3.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Nucleosomes consist of approximately 146 bp of DNA
            wrapped around a histone octamer composed of pairs of each of the
            four core histones (H2A, H2B, H3, and H4). The chromatin fiber is
            further compacted through the interaction of a linker histone, H1,
            with the DNA between the nucleosomes to form higher order chromatin
            structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H2B
            family. Transcripts from this gene lack polyA tails; instead, they
            contain a palindromic termination element. [provided by RefSeq, Aug
            2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: CX234648.1, BC060304.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-464               AL592149.8         52006-52469
FEATURES             Location/Qualifiers
     source          1..464
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 9.8 cM"
     gene            1..464
                     /gene="H2bc8"
                     /gene_synonym="H2bc4; H2bc6; Hist1h2bg"
                     /note="H2B clustered histone 8"
                     /db_xref="GeneID:319181"
                     /db_xref="MGI:MGI:2448386"
     exon            1..464
                     /gene="H2bc8"
                     /gene_synonym="H2bc4; H2bc6; Hist1h2bg"
                     /inference="alignment:Splign:2.1.0"
     CDS             34..414
                     /gene="H2bc8"
                     /gene_synonym="H2bc4; H2bc6; Hist1h2bg"
                     /note="histone 1, H2bg; histone cluster 1, H2bg"
                     /codon_start=1
                     /product="histone H2B type 1-C/E/G"
                     /protein_id="NP_835503.1"
                     /db_xref="CCDS:CCDS26349.1"
                     /db_xref="GeneID:319181"
                     /db_xref="MGI:MGI:2448386"
                     /translation="MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYK
                     VLKQVHPDTGISSKAMGIMNSFVNDIFERIAGEASRLAHYNKRSTITSREIQTAVRLL
                     LPGELAKHAVSEGTKAVTKYTSSK"
ORIGIN      
        1 gttttatctt tctctttgtt gcttgtttct accatgcccg agcctgcgaa gtccgctcct
       61 gccccgaaga agggctccaa gaaggccgtg accaaggccc agaagaagga cggcaagaag
      121 cgcaagcgca gccgcaagga gagctactcg gtgtacgtgt acaaggtgct gaagcaagtg
      181 caccccgaca ccggcatctc ctccaaggcc atgggcatca tgaactcgtt cgtgaacgac
      241 atcttcgagc gcatcgcggg cgaggcgtcc cgcctggcgc attacaacaa gcgctcgacc
      301 atcacgtccc gggagatcca gacggccgtg cgcctgctgc tgcccgggga gctggccaag
      361 cacgccgtgt cggagggcac caaggctgtc actaagtaca ccagctccaa gtgagttcat
      421 ttaactcaca ctcctaaccc aaaggctctt ttcagagcca ccca
//
