LOCUS       NM_030082                462 bp    mRNA    linear   ROD 04-APR-2024
DEFINITION  Mus musculus H2B clustered histone 27 (H2bc27), mRNA.
ACCESSION   NM_030082
VERSION     NM_030082.4
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 462)
  AUTHORS   Cheverud,J.M., Lawson,H.A., Bouckaert,K., Kossenkov,A.V.,
            Showe,L.C., Cort,L., Blankenhorn,E.P., Bedelbaeva,K.,
            Gourevitch,D., Zhang,Y. and Heber-Katz,E.
  TITLE     Fine-mapping quantitative trait loci affecting murine external ear
            tissue regeneration in the LG/J by SM/J advanced intercross line
  JOURNAL   Heredity (Edinb) 112 (5), 508-518 (2014)
   PUBMED   24569637
REFERENCE   2  (bases 1 to 462)
  AUTHORS   Golas,A., Dzieza,A., Kuzniarz,K. and Styrna,J.
  TITLE     Gene mapping of sperm quality parameters in recombinant inbred
            strains of mice
  JOURNAL   Int J Dev Biol 52 (2-3), 287-293 (2008)
   PUBMED   18311719
REFERENCE   3  (bases 1 to 462)
  AUTHORS   Chakravarthy,S., Gundimella,S.K., Caron,C., Perche,P.Y.,
            Pehrson,J.R., Khochbin,S. and Luger,K.
  TITLE     Structural characterization of the histone variant macroH2A
  JOURNAL   Mol Cell Biol 25 (17), 7616-7624 (2005)
   PUBMED   16107708
REFERENCE   4  (bases 1 to 462)
  AUTHORS   Odegard,V.H., Kim,S.T., Anderson,S.M., Shlomchik,M.J. and
            Schatz,D.G.
  TITLE     Histone modifications associated with somatic hypermutation
  JOURNAL   Immunity 23 (1), 101-110 (2005)
   PUBMED   16039583
REFERENCE   5  (bases 1 to 462)
  AUTHORS   Fernandez-Capetillo,O., Allis,C.D. and Nussenzweig,A.
  TITLE     Phosphorylation of histone H2B at DNA double-strand breaks
  JOURNAL   J Exp Med 199 (12), 1671-1677 (2004)
   PUBMED   15197225
REFERENCE   6  (bases 1 to 462)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL662809.14.
            
            On Mar 6, 2014 this sequence version replaced NM_030082.3.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Nucleosomes consist of approximately 146 bp of DNA
            wrapped around a histone octamer composed of pairs of each of the
            four core histones (H2A, H2B, H3, and H4). The chromatin fiber is
            further compacted through the interaction of a linker histone, H1,
            with the DNA between the nucleosomes to form higher order chromatin
            structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H2B
            family. [provided by RefSeq, Sep 2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BU841543.1, AK018765.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-462               AL662809.14        33383-33844
FEATURES             Location/Qualifiers
     source          1..462
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 36.38 cM"
     gene            1..462
                     /gene="H2bc27"
                     /gene_synonym="1500011O09Rik; H2bu2; Hist3h2ba"
                     /note="H2B clustered histone 27"
                     /db_xref="GeneID:78303"
                     /db_xref="MGI:MGI:1925553"
     exon            1..462
                     /gene="H2bc27"
                     /gene_synonym="1500011O09Rik; H2bu2; Hist3h2ba"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..410
                     /gene="H2bc27"
                     /gene_synonym="1500011O09Rik; H2bu2; Hist3h2ba"
                     /note="histone 3, H2ba; histone H2B type 3-A; histone
                     cluster 3, H2ba"
                     /codon_start=1
                     /product="H2B.U histone 2"
                     /protein_id="NP_084358.1"
                     /db_xref="CCDS:CCDS24754.1"
                     /db_xref="GeneID:78303"
                     /db_xref="MGI:MGI:1925553"
                     /translation="MPEPSRSTPAPKKGSKKAITKAQKKDGKKRKRGRKESYSIYVYK
                     VLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLL
                     LPGELAKHAVSEGTKAVTKYTSSK"
ORIGIN      
        1 gttcgtctgg gtgcagccag tgcagcagga tgccggagcc ttcccgctcc actcccgccc
       61 cgaagaaagg ctccaagaaa gccatcacca aggctcagaa aaaggatggc aagaaacgca
      121 aacggggccg caaggagagc tactccatct acgtgtacaa ggtgctgaag caggtgcatc
      181 cggacaccgg catctcgtcc aaggccatgg gcatcatgaa ctcgttcgtc aatgacatct
      241 tcgagcgcat cgccagcgag gcctcccgcc tggcgcatta caacaagcgc tcgaccatca
      301 cgtcccgcga ggtgcagacg gccgtgcgcc tgctgctgcc cggggagctg gccaagcatg
      361 ccgtgtccga gggcaccaag gcagtcacca aatacaccag ctccaagtga ggcgcggcga
      421 gagcgccccc aacccaaagg ctcttttcag agccaccttc ca
//
