LOCUS       NM_001393523            2318 bp    mRNA    linear   ROD 12-JUN-2024
DEFINITION  Mus musculus H2B clustered histone 26 (H2bc26), mRNA.
ACCESSION   NM_001393523
VERSION     NM_001393523.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2318)
  AUTHORS   Golas,A., Dzieza,A., Kuzniarz,K. and Styrna,J.
  TITLE     Gene mapping of sperm quality parameters in recombinant inbred
            strains of mice
  JOURNAL   Int J Dev Biol 52 (2-3), 287-293 (2008)
   PUBMED   18311719
REFERENCE   2  (bases 1 to 2318)
  AUTHORS   Kim,S.C., Sprung,R., Chen,Y., Xu,Y., Ball,H., Pei,J., Cheng,T.,
            Kho,Y., Xiao,H., Xiao,L., Grishin,N.V., White,M., Yang,X.J. and
            Zhao,Y.
  TITLE     Substrate and functional diversity of lysine acetylation revealed
            by a proteomics survey
  JOURNAL   Mol Cell 23 (4), 607-618 (2006)
   PUBMED   16916647
REFERENCE   3  (bases 1 to 2318)
  AUTHORS   Odegard,V.H., Kim,S.T., Anderson,S.M., Shlomchik,M.J. and
            Schatz,D.G.
  TITLE     Histone modifications associated with somatic hypermutation
  JOURNAL   Immunity 23 (1), 101-110 (2005)
   PUBMED   16039583
REFERENCE   4  (bases 1 to 2318)
  AUTHORS   Fernandez-Capetillo,O., Allis,C.D. and Nussenzweig,A.
  TITLE     Phosphorylation of histone H2B at DNA double-strand breaks
  JOURNAL   J Exp Med 199 (12), 1671-1677 (2004)
   PUBMED   15197225
REFERENCE   5  (bases 1 to 2318)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AL662809.14.
            
            Summary: Histones are basic nuclear proteins responsible for
            nucleosome structure of the chromosomal fiber in eukaryotes. Two
            molecules of each of the four core histones (H2A, H2B, H3, and H4)
            form an octamer, around which approximately 146 bp of DNA is
            wrapped in repeating units, called nucleosomes. The linker histone,
            H1, interacts with linker DNA between nucleosomes and functions in
            the compaction of chromatin into higher order structures. This gene
            encodes a replication-dependent histone that is a member of the
            histone H2b family. [provided by RefSeq, Feb 2021].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC107301.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-2318              AL662809.14        36607-38924         c
FEATURES             Location/Qualifiers
     source          1..2318
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 36.38 cM"
     gene            1..2318
                     /gene="H2bc26"
                     /gene_synonym="4930534G10Rik; 4933432H21; B2Hist3h2bb;
                     H2bc26-ps; H2bu1; H2bu1-ps; Hist3h2bb; Hist3h2bb-ps"
                     /note="H2B clustered histone 26"
                     /db_xref="GeneID:382522"
                     /db_xref="MGI:MGI:1922442"
     exon            1..2318
                     /gene="H2bc26"
                     /gene_synonym="4930534G10Rik; 4933432H21; B2Hist3h2bb;
                     H2bc26-ps; H2bu1; H2bu1-ps; Hist3h2bb; Hist3h2bb-ps"
                     /inference="alignment:Splign:2.1.0"
     CDS             25..405
                     /gene="H2bc26"
                     /gene_synonym="4930534G10Rik; 4933432H21; B2Hist3h2bb;
                     H2bc26-ps; H2bu1; H2bu1-ps; Hist3h2bb; Hist3h2bb-ps"
                     /note="histone 3, H2bb; H2B.U histone 1, pseudogene;
                     histone cluster 3, H2bb, pseudogene"
                     /codon_start=1
                     /product="histone H2B type 3-B"
                     /protein_id="NP_001380452.1"
                     /db_xref="GeneID:382522"
                     /db_xref="MGI:MGI:1922442"
                     /translation="MPDPSKSAPAPKKGSKKAVTKAQKKDGKKRKRGRKESYSIYVYK
                     VLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREVQTAVRLL
                     LPGELAKHAVSEGTKAVTKYTSSK"
     regulatory      1020..1025
                     /regulatory_class="polyA_signal_sequence"
                     /gene="H2bc26"
                     /gene_synonym="4930534G10Rik; 4933432H21; B2Hist3h2bb;
                     H2bc26-ps; H2bu1; H2bu1-ps; Hist3h2bb; Hist3h2bb-ps"
                     /note="hexamer: AGTAAA"
     polyA_site      1042
                     /gene="H2bc26"
                     /gene_synonym="4930534G10Rik; 4933432H21; B2Hist3h2bb;
                     H2bc26-ps; H2bu1; H2bu1-ps; Hist3h2bb; Hist3h2bb-ps"
                     /note="major polyA site"
     regulatory      2299..2304
                     /regulatory_class="polyA_signal_sequence"
                     /gene="H2bc26"
                     /gene_synonym="4930534G10Rik; 4933432H21; B2Hist3h2bb;
                     H2bc26-ps; H2bu1; H2bu1-ps; Hist3h2bb; Hist3h2bb-ps"
                     /note="hexamer: AATAAA"
     polyA_site      2318
                     /gene="H2bc26"
                     /gene_synonym="4930534G10Rik; 4933432H21; B2Hist3h2bb;
                     H2bc26-ps; H2bu1; H2bu1-ps; Hist3h2bb; Hist3h2bb-ps"
                     /note="major polyA site"
ORIGIN      
        1 gtttccgtag tacaactaga cattatgcct gatccatcca aatcagctcc agcccccaag
       61 aaaggctcca aaaaggcggt caccaaggcg cagaaaaagg atggcaagaa acgcaaacgg
      121 ggccgcaagg agagctactc catctacgtg tacaaggtgc tgaagcaggt gcatccggac
      181 accggcatct cgtctaaggc catgggcatc atgaactcgt tcgtcaatga catcttcgag
      241 cgcatcgcca gcgaggcctc ccgcctggcg cattacaaca agcgctcgac catcacgtcc
      301 cgcgaggtgc agacagccgt gcgcctgctg ctgcccgggg agctggccaa gcatgctgtg
      361 tccgagggca ccaaggcagt caccaaatac accagctcca agtgaggcgc ggcgagggtg
      421 ccctcaattc aaaggctctt ttcagagcca cccatacagt cgttaaaagg gtcttgaaca
      481 cagtgcgggc cactgacgat tgccacgcgc ccgaggcgtt ccctgacact gggtgcggcc
      541 aagtccgatt tttgagcgag aaatgtgggg gtatggctgc tttgcccttc ctaagcgtag
      601 agtgtgaacg acagctgcag gagcaggcaa ggggcgtgag tcctctcccc aagcctgaag
      661 tttcggtggg cgaggtcaca gtgaggtggt attctggatg tgggccccct tggtggcctc
      721 tgaatctgtg ttccctttag caccctttcc atccttttct ggaatagaga ggcgtcttta
      781 gcccctgaaa actattctga cattatatca tgtcaataaa ccctgcacta gcagtatgct
      841 ggaaacgggg cggggggagg ggcggcacac cgcaaagcct gtgtgcagga gctaggatgt
      901 aattagcctg agctgccagc aagcagtttc agtggttagg ggatgggagg tgggaaagag
      961 ttccgttgtt ttgagcaaga gttgttcccc taaagctgca taattttctg tgaagcatta
     1021 gtaaaagaat aatccacact cagcatttat ttggagaacg tcattaaaaa tttttttatt
     1081 agatattttc tttatttaca tttcaaatcc tatctccctt tctggtttcc cctccgaaaa
     1141 caccctattt cctcctcctt cccctgctca ccaacccacc cactcctgcc tgcttcctgg
     1201 ccctggcatt cccctacact ggggagaatg tcatttttat ggagaacgtt tgggcaggga
     1261 attttacctg tggaaagatc accactttcc ttggtttggc ttttatttat gaaaagagga
     1321 ttcgtgataa ttatttgagt tgttacgaga catattgaga atcctatagt caccagcagg
     1381 gaatactacg tacattttat ttttttacca agttgtcaaa gggagcccct ctcatctgga
     1441 ctcaggcatt tgacatttgg catttgaggg gaggctatct ctgcttgaac ttcctacagt
     1501 agctgtgcca ccttctgctt tccagcttgg tccacagaaa agggtttttg atagcatcat
     1561 gtgttttaaa gttagcatct gaagcatttt tatctgaagt tcaagtaact gcaaagatac
     1621 aaatgacaaa ccaggaattt ttttaaaaat cattttttta aaaccattct tgaaaatacc
     1681 tattgcttca tcaatttaat acaagtcagg tcaaaataat tcttaaaaag atatttcata
     1741 ttattctctt tgaaaatatc tctcttattt tccttctgcc aacaacagtt acatgtatat
     1801 tacatttaac tatttgctgc ttccagaatt gtctattgaa atttaaacat gccaactaaa
     1861 ttatctcggt attttttttt aaaaaaaaag gacacaggga cggtggagaa tcggttaaga
     1921 catgaaccat ttagttttag taaaactagt ctttcactta ggtttgatgg gaggaggtat
     1981 actggctggt tttgtgtcaa caacacaggc tggggttatc acagagaaag gagcttcagt
     2041 tgaggaaatg cctccatgag atccaactgt aaggcatttt ctcaattagt gatcaagggg
     2101 gaaaggccct tgtggatggg accatctctg ggctggtagt cttaggttat ataagagagc
     2161 atgctgagaa agccagggga agcaagccag taaggaacat ccctccatgg cctctgcatc
     2221 agctcctgct ccctgacctg cttgagttcc agtcctgact tctttcagtg atgaacagca
     2281 gtttggaaat gtaagcggaa taaactcttt cttcccta
//
