LOCUS       NM_001110555            2121 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus H2B clustered histone 24 (H2bc24), transcript variant
            1, mRNA.
ACCESSION   NM_001110555 NR_003375 XM_978232
VERSION     NM_001110555.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2121)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   2  (bases 1 to 2121)
  AUTHORS   Kawai,J., Shinagawa,A., Shibata,K., Yoshino,M., Itoh,M., Ishii,Y.,
            Arakawa,T., Hara,A., Fukunishi,Y., Konno,H., Adachi,J., Fukuda,S.,
            Aizawa,K., Izawa,M., Nishi,K., Kiyosawa,H., Kondo,S., Yamanaka,I.,
            Saito,T., Okazaki,Y., Gojobori,T., Bono,H., Kasukawa,T., Saito,R.,
            Kadota,K., Matsuda,H., Ashburner,M., Batalov,S., Casavant,T.,
            Fleischmann,W., Gaasterland,T., Gissi,C., King,B., Kochiwa,H.,
            Kuehl,P., Lewis,S., Matsuo,Y., Nikaido,I., Pesole,G.,
            Quackenbush,J., Schriml,L.M., Staubli,F., Suzuki,R., Tomita,M.,
            Wagner,L., Washio,T., Sakai,K., Okido,T., Furuno,M., Aono,H.,
            Baldarelli,R., Barsh,G., Blake,J., Boffelli,D., Bojunga,N.,
            Carninci,P., de Bonaldo,M.F., Brownstein,M.J., Bult,C.,
            Fletcher,C., Fujita,M., Gariboldi,M., Gustincich,S., Hill,D.,
            Hofmann,M., Hume,D.A., Kamiya,M., Lee,N.H., Lyons,P.,
            Marchionni,L., Mashima,J., Mazzarelli,J., Mombaerts,P., Nordone,P.,
            Ring,B., Ringwald,M., Rodriguez,I., Sakamoto,N., Sasaki,H.,
            Sato,K., Schonbach,C., Seya,T., Shibata,Y., Storch,K.F., Suzuki,H.,
            Toyo-oka,K., Wang,K.H., Weitz,C., Whittaker,C., Wilming,L.,
            Wynshaw-Boris,A., Yoshida,K., Hasegawa,Y., Kawaji,H., Kohtsuki,S.
            and Hayashizaki,Y.
  CONSRTM   RIKEN Genome Exploration Research Group Phase II Team and the
            FANTOM Consortium
  TITLE     Functional annotation of a full-length mouse cDNA collection
  JOURNAL   Nature 409 (6821), 685-690 (2001)
   PUBMED   11217851
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL589879.21.
            
            On Nov 17, 2007 this sequence version replaced NR_003375.1.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. This structure consists of approximately 146 bp of DNA
            wrapped around a nucleosome, an octamer composed of pairs of each
            of the four core histones (H2A, H2B, H3, and H4). The chromatin
            fiber is further compacted through the interaction of a linker
            histone, H1, with the DNA between the nucleosomes to form higher
            order chromatin structures. This gene encodes a
            replication-dependent histone that is a member of the histone H2B
            family and generates two transcripts through the use of the
            conserved stem-loop termination motif, and the polyA addition
            motif. [provided by RefSeq, Sep 2015].
            
            Transcript Variant: This variant (1) encodes the longer isoform
            (1).
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR11927932.3769220.1,
                                           SRR11927938.3628509.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on expression, longest
                                             protein
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-405               AL589879.21        33910-34314
            406-2121            AL589879.21        35982-37697
FEATURES             Location/Qualifiers
     source          1..2121
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 8.0 cM"
     gene            1..2121
                     /gene="H2bc24"
                     /gene_synonym="Gm11277; H4bc24; Hist1h2br"
                     /note="H2B clustered histone 24"
                     /db_xref="GeneID:665622"
                     /db_xref="MGI:MGI:3710645"
     exon            1..405
                     /gene="H2bc24"
                     /gene_synonym="Gm11277; H4bc24; Hist1h2br"
                     /inference="alignment:Splign:2.1.0"
     CDS             29..433
                     /gene="H2bc24"
                     /gene_synonym="Gm11277; H4bc24; Hist1h2br"
                     /note="isoform 1 is encoded by transcript variant 1; H2b
                     histone family member; histone cluster 1 H2br"
                     /codon_start=1
                     /product="histone cluster 1 H2br isoform 1"
                     /protein_id="NP_001104025.1"
                     /db_xref="CCDS:CCDS49215.1"
                     /db_xref="GeneID:665622"
                     /db_xref="MGI:MGI:3710645"
                     /translation="MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYK
                     VLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLL
                     LPGELAKHAVSEGTKAVTKYTSSNFSRQNFSV"
     exon            406..2121
                     /gene="H2bc24"
                     /gene_synonym="Gm11277; H4bc24; Hist1h2br"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2093..2098
                     /regulatory_class="polyA_signal_sequence"
                     /gene="H2bc24"
                     /gene_synonym="Gm11277; H4bc24; Hist1h2br"
                     /note="hexamer: ATTAAA"
     polyA_site      2121
                     /gene="H2bc24"
                     /gene_synonym="Gm11277; H4bc24; Hist1h2br"
                     /note="major polyA site"
ORIGIN      
        1 gctagagttc cagagttcca gtctcatcat gcctgagcct gcgaagtccg ctcccgcccc
       61 gaagaagggc tccaagaagg ccgtcaccaa ggcccagaag aaggacggca agaagcgcaa
      121 gcgcagccgc aaggagagct actcggtgta cgtgtacaag gtgctgaagc aagtgcaccc
      181 cgacaccggc atctcctcca aggccatggg catcatgaac tcgttcgtga acgacatctt
      241 cgagcgcatc gcgagcgagg cgtcccgcct ggcgcattac aacaagcgct cgaccatcac
      301 gtcccgggag atccagacgg ccgtgcgcct gctgctgccc ggggagctgg ccaagcacgc
      361 ggtgtcggag ggcaccaagg ccgtcaccaa gtacaccagc tccaattttt caagacaaaa
      421 tttctctgtg tagccctggc tctcctggaa ctcactctgt agatcagact gcccttgaac
      481 tcagagatcc acctgagtgc tgggattaaa ggtgagtgcc actaccccca gtttgagtca
      541 ttttcttttc cttgcatcct tttaaggtaa attaacactt gtgcctatac tacaggtcgc
      601 aaggcacgtg ttcagtgaca gttaagaaat tgcttgagtt tgcacggcta atgagtggaa
      661 actggcttaa gaactttcag aacgcttgct cgtcgccacc gagtgtcatc accgcctgtc
      721 taaaggttga tctgtgatga gtgtcttcaa gacacagaca gtgacaagta gttacaagta
      781 gtagcaccgt gtacctgtgt atgttttcgt gaattcgaaa gtaacccctt taggagatag
      841 gtaccaggaa aagcccctcc ctcaacaaaa tggcttacac tcgctggtaa gtcgtccttt
      901 tcctgtcagg aatcaaaatc ccaaccccct tggcctgacc cattaaaggg ccttctgtcc
      961 ccttaatgaa accctccagc tcacccagac agacttccac tggtgagcct ttaaaggtgt
     1021 ctggggttgg tttgtttggt tggttgtttt gttttgtttt ttacttatct tgtctccctt
     1081 ccctatagct gccaaacctg gtgtttcctg tctcaaaagt caatcaaatt tcatagagtt
     1141 cccttctgag tcaactttaa aatactttta tagatgaaat caagaacctg cgcagggacc
     1201 gtgagttccc taatgacaga agaatattaa ataaatttgt ttcttctcct gcctcctacc
     1261 ccacttttga cacagtgtct tgttatgtgt ttatccacag aaactagaag tgtgcaaaag
     1321 gcctcacctc ctacactgct cccatgggat tatgttcact gtacatgtta tttgtggaga
     1381 aatcagtata gctcagaaac aaggccctga aatctaacct tatccactag ggtaccttcc
     1441 tcagcagtgt ttccttcaga gtttggttgt tttgttttgt tttgttttgt tttgttttgt
     1501 tttgtttttc acaaactgca tgtaatgatc agatacagcg ggccgactct agtaagatgc
     1561 ttgcctatga gaaatatatc gatgatacgg aaacacacaa gaaatagtaa tgaagaagct
     1621 ggagcggtag actggtcagc aattcagagc ccttactact tttcacaaga acctgagttc
     1681 ggttcccagc acccctggca ggtgtgacac aatcagctgt aactctgact ccagcgcatc
     1741 caacacccac ctctgatcta ggtgtactgt gtgaccagta cccaaacacg tggcgtactt
     1801 gtcacacagg caaaaaggca tatgtaaata aaatgaaaga cccaactacc aaacagacca
     1861 tgtaggtttt actgggatgc ttggatctga ggaccataag gaaaagtcta aaacctaaaa
     1921 gagatggtaa tacaaaaggc tctgtactaa agaacatttt tatgattctg tgaggtgatt
     1981 ataacttgtc tcagcaatag ccagctcacc ataatacact acagttttct atctcttcat
     2041 aaacctttga gatggtaagt atgccaacta cagtcatgtg tgtgtatctg tcattaaaat
     2101 tggatagtct atatactttt a
//
