LOCUS       NM_178199                473 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus H2B clustered histone 13 (H2bc13), mRNA.
ACCESSION   NM_178199
VERSION     NM_178199.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 473)
  AUTHORS   Das,R., Burke,T. and Plow,E.F.
  TITLE     Histone H2B as a functionally important plasminogen receptor on
            macrophages
  JOURNAL   Blood 110 (10), 3763-3772 (2007)
   PUBMED   17690254
REFERENCE   2  (bases 1 to 473)
  AUTHORS   Kim,S.C., Sprung,R., Chen,Y., Xu,Y., Ball,H., Pei,J., Cheng,T.,
            Kho,Y., Xiao,H., Xiao,L., Grishin,N.V., White,M., Yang,X.J. and
            Zhao,Y.
  TITLE     Substrate and functional diversity of lysine acetylation revealed
            by a proteomics survey
  JOURNAL   Mol Cell 23 (4), 607-618 (2006)
   PUBMED   16916647
REFERENCE   3  (bases 1 to 473)
  AUTHORS   Odegard,V.H., Kim,S.T., Anderson,S.M., Shlomchik,M.J. and
            Schatz,D.G.
  TITLE     Histone modifications associated with somatic hypermutation
  JOURNAL   Immunity 23 (1), 101-110 (2005)
   PUBMED   16039583
REFERENCE   4  (bases 1 to 473)
  AUTHORS   Fernandez-Capetillo,O., Allis,C.D. and Nussenzweig,A.
  TITLE     Phosphorylation of histone H2B at DNA double-strand breaks
  JOURNAL   J Exp Med 199 (12), 1671-1677 (2004)
   PUBMED   15197225
REFERENCE   5  (bases 1 to 473)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   6  (bases 1 to 473)
  AUTHORS   Wang,Z.F., Krasikov,T., Frey,M.R., Wang,J., Matera,A.G. and
            Marzluff,W.F.
  TITLE     Characterization of the mouse histone gene cluster on chromosome
            13: 45 histone genes in three patches spread over 1Mb
  JOURNAL   Genome Res 6 (8), 688-701 (1996)
   PUBMED   8858344
REFERENCE   7  (bases 1 to 473)
  AUTHORS   Liu,T.J., Liu,L. and Marzluff,W.F.
  TITLE     Mouse histone H2A and H2B genes: four functional genes and a
            pseudogene undergoing gene conversion with a closely linked
            functional gene
  JOURNAL   Nucleic Acids Res 15 (7), 3023-3039 (1987)
   PUBMED   3562244
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL589651.8.
            
            On Jun 19, 2019 this sequence version replaced NM_178199.2.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Two molecules of each of the four core histones (H2A,
            H2B, H3, and H4) form an octamer, around which approximately 146 bp
            of DNA is wrapped in repeating units, called nucleosomes. The
            linker histone, H1, interacts with linker DNA between nucleosomes
            and functions in the compaction of chromatin into higher order
            structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H2B
            family. Transcripts from this gene lack polyA tails but instead
            contain a palindromic termination element. [provided by RefSeq, Aug
            2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-473               AL589651.8         136701-137173       c
FEATURES             Location/Qualifiers
     source          1..473
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 7.93 cM"
     gene            1..473
                     /gene="H2bc13"
                     /gene_synonym="H2b-291a; H2bc11; H2bc15; H2bc7; Hist1h2bl"
                     /note="H2B clustered histone 13"
                     /db_xref="GeneID:319185"
                     /db_xref="MGI:MGI:2448403"
     exon            1..473
                     /gene="H2bc13"
                     /gene_synonym="H2b-291a; H2bc11; H2bc15; H2bc7; Hist1h2bl"
                     /inference="alignment:Splign:2.1.0"
     CDS             41..421
                     /gene="H2bc13"
                     /gene_synonym="H2b-291a; H2bc11; H2bc15; H2bc7; Hist1h2bl"
                     /note="H2B 291A; histone 1, H2bl; histone cluster 1, H2bl"
                     /codon_start=1
                     /product="histone H2B type 1-F/J/L"
                     /protein_id="NP_835506.1"
                     /db_xref="CCDS:CCDS26287.1"
                     /db_xref="GeneID:319185"
                     /db_xref="MGI:MGI:2448403"
                     /translation="MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYK
                     VLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLL
                     LPGELAKHAVSEGTKAVTKYTSSK"
     polyA_site      473
                     /gene="H2bc13"
                     /gene_synonym="H2b-291a; H2bc11; H2bc15; H2bc7; Hist1h2bl"
                     /note="major polyA site"
ORIGIN      
        1 agttatcctt tttcaactta gttcacttca tcctctcagt atgcctgagc ccgccaagtc
       61 cgctcccgcc ccgaagaagg gctccaagaa ggccgtcacc aaggcccaga agaaggacgg
      121 caagaagcgc aagcgcagcc gcaaggagag ctactcggtg tacgtgtaca aggtgctgaa
      181 gcaagtgcac cccgacaccg gcatctcctc caaggccatg ggcatcatga actcgttcgt
      241 gaacgacatc ttcgagcgca tcgcgagcga ggcttcccgc ctggcgcatt acaacaagcg
      301 ctcgaccatc acgtcccggg agatccagac ggccgtgcgc ctgctgctgc ccggggagct
      361 ggccaagcac gcggtgtcgg agggcaccaa ggcagtcacc aagtacacca gctccaagtg
      421 agctcgttta actcacactc ctaactcaaa ggctctttta agagccaccc aca
//
