LOCUS       NM_175665                500 bp    mRNA    linear   ROD 04-APR-2024
DEFINITION  Mus musculus H2B clustered histone 12 (H2bc12), mRNA.
ACCESSION   NM_175665
VERSION     NM_175665.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 500)
  AUTHORS   Das,R., Burke,T. and Plow,E.F.
  TITLE     Histone H2B as a functionally important plasminogen receptor on
            macrophages
  JOURNAL   Blood 110 (10), 3763-3772 (2007)
   PUBMED   17690254
REFERENCE   2  (bases 1 to 500)
  AUTHORS   Kim,S.C., Sprung,R., Chen,Y., Xu,Y., Ball,H., Pei,J., Cheng,T.,
            Kho,Y., Xiao,H., Xiao,L., Grishin,N.V., White,M., Yang,X.J. and
            Zhao,Y.
  TITLE     Substrate and functional diversity of lysine acetylation revealed
            by a proteomics survey
  JOURNAL   Mol Cell 23 (4), 607-618 (2006)
   PUBMED   16916647
REFERENCE   3  (bases 1 to 500)
  AUTHORS   Odegard,V.H., Kim,S.T., Anderson,S.M., Shlomchik,M.J. and
            Schatz,D.G.
  TITLE     Histone modifications associated with somatic hypermutation
  JOURNAL   Immunity 23 (1), 101-110 (2005)
   PUBMED   16039583
REFERENCE   4  (bases 1 to 500)
  AUTHORS   Fernandez-Capetillo,O., Allis,C.D. and Nussenzweig,A.
  TITLE     Phosphorylation of histone H2B at DNA double-strand breaks
  JOURNAL   J Exp Med 199 (12), 1671-1677 (2004)
   PUBMED   15197225
REFERENCE   5  (bases 1 to 500)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL590614.8.
            
            On Mar 1, 2014 this sequence version replaced NM_175665.1.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Two molecules of each of the four core histones (H2A,
            H2B, H3, and H4) form an octamer, around which approximately 146 bp
            of DNA is wrapped in repeating units, called nucleosomes. The
            linker histone, H1, interacts with linker DNA between nucleosomes
            and functions in the compaction of chromatin into higher order
            structures. This gene encodes a replication-dependent histone that
            is a member of the histone H2B family. [provided by RefSeq, Aug
            2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC147143.1, SRR7345562.2451065.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-500               AL590614.8         53177-53676
FEATURES             Location/Qualifiers
     source          1..500
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 8.14 cM"
     gene            1..500
                     /gene="H2bc12"
                     /gene_synonym="Hist1h2bk"
                     /note="H2B clustered histone 12"
                     /db_xref="GeneID:319184"
                     /db_xref="MGI:MGI:2448399"
     exon            1..500
                     /gene="H2bc12"
                     /gene_synonym="Hist1h2bk"
                     /inference="alignment:Splign:2.1.0"
     CDS             67..447
                     /gene="H2bc12"
                     /gene_synonym="Hist1h2bk"
                     /note="histone 1, H2bk; histone cluster 1, H2bk"
                     /codon_start=1
                     /product="histone H2B type 1-K"
                     /protein_id="NP_783596.1"
                     /db_xref="CCDS:CCDS26305.1"
                     /db_xref="GeneID:319184"
                     /db_xref="MGI:MGI:2448399"
                     /translation="MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYK
                     VLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLL
                     LPGELAKHAVSEGTKAVTKYTSAK"
ORIGIN      
        1 cccgtggtgt tcctatctgc ttgtcctgtt gggtgttcag ctttgttttc tattcatttc
       61 tacgccatgc ctgagcctgc gaagtccgct cccgccccga agaagggctc caagaaggcc
      121 gtcaccaagg cccagaagaa ggacggcaag aagcgcaagc gcagccgcaa ggagagctac
      181 tcggtgtacg tgtacaaggt gctgaagcaa gtgcaccccg acaccggcat ctcctccaag
      241 gccatgggca tcatgaactc gttcgtgaac gacatcttcg agcgcatcgc gagcgaggcg
      301 tcccgcctgg cgcattacaa caagcgctcg accatcacgt cccgggagat ccagacggcc
      361 gtgcgcctgc tgctgcccgg ggagctggcc aagcacgccg tgtcggaggg caccaaggct
      421 gtcaccaagt atactagcgc caagtaaact tctcaatagg gttgacgtct agcaccaaag
      481 gctcttttaa gagccactaa
//
