LOCUS       NM_178198                461 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus H2B clustered histone 11 (H2bc11), mRNA.
ACCESSION   NM_178198
VERSION     NM_178198.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 461)
  AUTHORS   Das,R., Burke,T. and Plow,E.F.
  TITLE     Histone H2B as a functionally important plasminogen receptor on
            macrophages
  JOURNAL   Blood 110 (10), 3763-3772 (2007)
   PUBMED   17690254
REFERENCE   2  (bases 1 to 461)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL590614.8.
            
            On Jun 19, 2019 this sequence version replaced NM_178198.2.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Two molecules of each of the four core histones (H2A,
            H2B, H3, and H4) form an octamer, around which approximately 146 bp
            of DNA is wrapped in repeating units, called nucleosomes. The
            linker histone, H1, interacts with linker DNA between nucleosomes
            and functions in the compaction of chromatin into higher order
            structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H2B
            family. Transcripts from this gene lack polyA tails but instead
            contain a palindromic termination element. [provided by RefSeq, Aug
            2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: SRR7345562.711390.1,
                                        ERR3363658.5327604.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-461               AL590614.8         60554-61014
FEATURES             Location/Qualifiers
     source          1..461
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 8.15 cM"
     gene            1..461
                     /gene="H2bc11"
                     /gene_synonym="H2bc13; H2bc15; H2bc7; Hist1h2bj"
                     /note="H2B clustered histone 11"
                     /db_xref="GeneID:319183"
                     /db_xref="MGI:MGI:2448388"
     exon            1..461
                     /gene="H2bc11"
                     /gene_synonym="H2bc13; H2bc15; H2bc7; Hist1h2bj"
                     /inference="alignment:Splign:2.1.0"
     CDS             33..413
                     /gene="H2bc11"
                     /gene_synonym="H2bc13; H2bc15; H2bc7; Hist1h2bj"
                     /note="H2B 291A; histone 1, H2bj; histone cluster 1, H2bj"
                     /codon_start=1
                     /product="histone H2B type 1-F/J/L"
                     /protein_id="NP_835505.1"
                     /db_xref="CCDS:CCDS26308.1"
                     /db_xref="GeneID:319183"
                     /db_xref="MGI:MGI:2448388"
                     /translation="MPEPAKSAPAPKKGSKKAVTKAQKKDGKKRKRSRKESYSVYVYK
                     VLKQVHPDTGISSKAMGIMNSFVNDIFERIASEASRLAHYNKRSTITSREIQTAVRLL
                     LPGELAKHAVSEGTKAVTKYTSSK"
     polyA_site      461
                     /gene="H2bc11"
                     /gene_synonym="H2bc13; H2bc15; H2bc7; Hist1h2bj"
                     /note="major polyA site"
ORIGIN      
        1 ggtatagctc tacgtagagg tcctgcttca ctatgcctga gcctgcgaag tccgctcccg
       61 ccccgaagaa gggctccaag aaggccgtca ccaaggccca gaagaaggac ggcaagaagc
      121 gcaagcgcag ccgcaaggag agctactcgg tgtacgtcta caaggtgctg aagcaagtgc
      181 accccgacac cggtatctcc tccaaggcca tgggcatcat gaactcgttc gtgaacgaca
      241 tcttcgagcg catcgcgagc gaggcgtccc gcctggcgca ttacaacaag cgctcgacca
      301 tcacgtcccg ggagatccag acggccgtgc gcctgctgct gcccggggag ctggccaagc
      361 acgcggtgtc ggagggcacc aaggccgtca ccaagtacac cagctccaag tgagcgctcc
      421 aggctgacac caaatccaaa ggctcttttc agagccacgc a
//
