LOCUS       NM_178189                487 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus H2A clustered histone 6 (H2ac6), mRNA.
ACCESSION   NM_178189
VERSION     NM_178189.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 487)
  AUTHORS   Gaudet,P., Livstone,M.S., Lewis,S.E. and Thomas,P.D.
  TITLE     Phylogenetic-based propagation of functional annotations within the
            Gene Ontology consortium
  JOURNAL   Brief Bioinform 12 (5), 449-462 (2011)
   PUBMED   21873635
REFERENCE   2  (bases 1 to 487)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL592149.8.
            
            On Feb 25, 2014 this sequence version replaced NM_178189.4.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Two molecules of each of the four core histones (H2A,
            H2B, H3, and H4) form an octamer, around which approximately 146 bp
            of DNA is wrapped in repeating units, called nucleosomes. The
            linker histone, H1, interacts with linker DNA between nucleosomes
            and functions in the compaction of chromatin into higher order
            structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H2A
            family. Transcripts from this gene lack polyA tails but instead
            contain a palindromic termination element. [provided by RefSeq, Aug
            2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK033518.1, BB624946.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-487               AL592149.8         163888-164374       c
FEATURES             Location/Qualifiers
     source          1..487
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 9.87 cM"
     gene            1..487
                     /gene="H2ac6"
                     /gene_synonym="Hist1h2ac"
                     /note="H2A clustered histone 6"
                     /db_xref="GeneID:319164"
                     /db_xref="MGI:MGI:2448287"
     exon            1..487
                     /gene="H2ac6"
                     /gene_synonym="Hist1h2ac"
                     /inference="alignment:Splign:2.1.0"
     CDS             43..435
                     /gene="H2ac6"
                     /gene_synonym="Hist1h2ac"
                     /note="histone H2A type 1; histone 1, H2ac; histone
                     cluster 1, H2ac"
                     /codon_start=1
                     /product="histone H2A type 1-C"
                     /protein_id="NP_835496.1"
                     /db_xref="CCDS:CCDS26356.1"
                     /db_xref="GeneID:319164"
                     /db_xref="MGI:MGI:2448287"
                     /translation="MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERV
                     GAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVT
                     IAQGGVLPNIQAVLLPKKTESHHKAKGK"
     polyA_site      487
                     /gene="H2ac6"
                     /gene_synonym="Hist1h2ac"
                     /note="major polyA site"
ORIGIN      
        1 aacttgtttt tactgttctg ttacttacac agcactatta ctatgtctgg acgtggtaag
       61 cagggcggca aggctcgcgc caaggccaag acccgctcct cccgggccgg cctgcagttc
      121 cccgtgggcc gcgtgcaccg gctgctccgc aagggtaact actcggagcg cgtgggcgcc
      181 ggcgccccgg tctacctggc ggccgtgctg gagtacctga cggccgagat cctggagctg
      241 gcgggcaacg cggcccgcga caacaagaag acgcgcatca tcccgcgcca cctgcagctg
      301 gccatccgca acgacgagga gctcaacaag ctgctgggcc gcgtgaccat cgcgcagggc
      361 ggcgtcctgc ccaacatcca ggccgtgctg ctgcccaaga agaccgagag ccaccacaag
      421 gccaagggga aataagcaac agaatctgcg gaaacttcaa acccaaaggc tcttttcaga
      481 gccccca
//
