LOCUS       NM_178185                452 bp    mRNA    linear   ROD 09-FEB-2024
DEFINITION  Mus musculus H2A clustered histone 24 (H2ac24), mRNA.
ACCESSION   NM_178185
VERSION     NM_178185.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 452)
  AUTHORS   Yamada,R., Oguri,A., Fujiki,K., Shirahige,K., Takezoe,H.,
            Takahashi,N. and Kanai,Y.
  TITLE     Single-cell transcriptional analysis reveals developmental
            stage-dependent changes in retinal progenitors in the murine early
            optic vesicle
  JOURNAL   Biochem Biophys Res Commun 543, 80-86 (2021)
   PUBMED   33548738
REFERENCE   2  (bases 1 to 452)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL589879.21.
            
            On Mar 1, 2014 this sequence version replaced NM_178185.1.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. This structure consists of approximately 146 bp of DNA
            wrapped around a nucleosome, an octamer composed of pairs of each
            of the four core histones (H2A, H2B, H3, and H4). The chromatin
            fiber is further compacted through the interaction of a linker
            histone, H1, with the DNA between the nucleosomes to form higher
            order chromatin structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H2A
            family. Transcripts from this gene lack polyA tails; instead, they
            contain a palindromic termination element. [provided by RefSeq, Sep
            2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AA138954.1, CF740975.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-452               AL589879.21        33191-33642         c
FEATURES             Location/Qualifiers
     source          1..452
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 8.0 cM"
     gene            1..452
                     /gene="H2ac24"
                     /gene_synonym="Gm11276; Hist1h2ap"
                     /note="H2A clustered histone 24"
                     /db_xref="GeneID:319171"
                     /db_xref="MGI:MGI:3710573"
     exon            1..452
                     /gene="H2ac24"
                     /gene_synonym="Gm11276; Hist1h2ap"
                     /inference="alignment:Splign:2.1.0"
     CDS             1..393
                     /gene="H2ac24"
                     /gene_synonym="Gm11276; Hist1h2ap"
                     /note="histone H2A type 1; Histone H2A type 1-O; histone
                     cluster 1, H2ap"
                     /codon_start=1
                     /product="histone H2A type 1-P"
                     /protein_id="NP_835492.1"
                     /db_xref="CCDS:CCDS26301.1"
                     /db_xref="GeneID:319171"
                     /db_xref="MGI:MGI:3710573"
                     /translation="MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERV
                     GAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVT
                     IAQGGVLPNIQAVLLPKKTESHHKAKGK"
ORIGIN      
        1 atgtctggac gcggcaagca gggtggcaag gctcgcgcca aggccaagac ccgctcctcc
       61 cgggccggcc tgcagttccc cgtgggccgc gtgcaccggc tgctccgcaa gggcaactac
      121 tcggagcgcg tgggcgccgg cgccccggtc tacctggcgg ccgtgctgga gtacctgacg
      181 gccgagatcc tggagctggc gggcaacgcg gcccgcgaca acaagaagac gcgcatcatc
      241 ccgcgccacc tgcagctggc catccgcaac gacgaggagc tcaacaagct gctgggccgc
      301 gtgaccatcg cgcagggcgg cgtcctgccc aacatccagg ccgtgctgct gcccaagaag
      361 accgagagcc accacaaggc caagggaaaa taagaccagc cgttcactca cccgaaaaga
      421 aaaaaaaaaa aggctctttt cagagccatc ca
//
