LOCUS       NM_001177544             552 bp    mRNA    linear   ROD 04-APR-2024
DEFINITION  Mus musculus H2A clustered histone 23 (H2ac23), mRNA.
ACCESSION   NM_001177544 XM_978341
VERSION     NM_001177544.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 552)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   2  (bases 1 to 552)
  AUTHORS   Fecker,L., Ekblom,P., Kurkinen,M. and Ekblom,M.
  TITLE     A genomic clone encoding a novel proliferation-dependent histone
            H2A.1 mRNA enriched in the poly(A)+ fraction
  JOURNAL   Mol Cell Biol 10 (6), 2848-2854 (1990)
   PUBMED   1971418
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL589879.21.
            
            On Mar 1, 2014 this sequence version replaced NM_001177544.1.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. This structure consists of approximately 146 bp of DNA
            wrapped around a nucleosome, an octamer composed of pairs of each
            of the four core histones (H2A, H2B, H3, and H4). The chromatin
            fiber is further compacted through the interaction of a linker
            histone, H1, with the DNA between the nucleosomes to form higher
            order chromatin structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H2A
            family. Transcripts from this gene lack polyA tails; instead, they
            contain a palindromic termination element. [provided by RefSeq, Aug
            2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC147161.1, CJ166671.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-552               AL589879.21        10534-11085
FEATURES             Location/Qualifiers
     source          1..552
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 7.99 cM"
     gene            1..552
                     /gene="H2ac23"
                     /gene_synonym="Hist1h2ao; Hist1h2ap"
                     /note="H2A clustered histone 23"
                     /db_xref="GeneID:665433"
                     /db_xref="MGI:MGI:2448302"
     exon            1..552
                     /gene="H2ac23"
                     /gene_synonym="Hist1h2ao; Hist1h2ap"
                     /inference="alignment:Splign:2.1.0"
     CDS             101..493
                     /gene="H2ac23"
                     /gene_synonym="Hist1h2ao; Hist1h2ap"
                     /note="histone H2A type 1; Histone H2A type 1-P; histone
                     cluster 1, H2ao"
                     /codon_start=1
                     /product="histone H2A type 1-O"
                     /protein_id="NP_001171015.1"
                     /db_xref="CCDS:CCDS49214.1"
                     /db_xref="GeneID:665433"
                     /db_xref="MGI:MGI:2448302"
                     /translation="MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERV
                     GAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVT
                     IAQGGVLPNIQAVLLPKKTESHHKAKGK"
ORIGIN      
        1 ccaatcgcat aggccctttt ttgcgcccag agaaaactat aagggccaag ctcttgctct
       61 ttgcaagcgt acggttttca gaagctgtct actttctacc atgtctggac gcggcaagca
      121 gggtggcaag gctcgcgcca aggccaagac ccgctcctcc cgggccggcc tgcagttccc
      181 cgtgggccgc gtgcaccggc tgctccgcaa gggcaactac tcggagcgcg tgggcgccgg
      241 cgccccggtc tacctggcgg ccgtgctgga gtacctgacg gccgagatcc tggagctggc
      301 gggcaacgcg gcccgcgaca acaagaagac gcgcatcatc ccgcgccacc tgcagctggc
      361 catccgcaac gacgaggagc tcaacaagct gctgggccgc gtgaccatcg cgcagggcgg
      421 cgtcctgccc aacatccagg ccgtgctgct gcccaagaag accgagagcc accacaaggc
      481 caagggaaaa taagaccagc cgttcactca cccgaaaaga aaaaaaaaaa aggctctttt
      541 cagagccatc ca
//
