LOCUS       NM_175659                522 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus H2A clustered histone 12 (H2ac12), mRNA.
ACCESSION   NM_175659
VERSION     NM_175659.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 522)
  AUTHORS   Ancelin,K., Lange,U.C., Hajkova,P., Schneider,R., Bannister,A.J.,
            Kouzarides,T. and Surani,M.A.
  TITLE     Blimp1 associates with Prmt5 and directs histone arginine
            methylation in mouse germ cells
  JOURNAL   Nat Cell Biol 8 (6), 623-630 (2006)
   PUBMED   16699504
REFERENCE   2  (bases 1 to 522)
  AUTHORS   Fang,J., Chen,T., Chadwick,B., Li,E. and Zhang,Y.
  TITLE     Ring1b-mediated H2A ubiquitination associates with inactive X
            chromosomes and is involved in initiation of X inactivation
  JOURNAL   J Biol Chem 279 (51), 52812-52815 (2004)
   PUBMED   15509584
REFERENCE   3  (bases 1 to 522)
  AUTHORS   de Napoles,M., Mermoud,J.E., Wakao,R., Tang,Y.A., Endoh,M.,
            Appanah,R., Nesterova,T.B., Silva,J., Otte,A.P., Vidal,M.,
            Koseki,H. and Brockdorff,N.
  TITLE     Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A
            to heritable gene silencing and X inactivation
  JOURNAL   Dev Cell 7 (5), 663-676 (2004)
   PUBMED   15525528
REFERENCE   4  (bases 1 to 522)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from BC139479.1.
            
            On Mar 1, 2014 this sequence version replaced NM_175659.1.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. Two molecules of each of the four core histones (H2A,
            H2B, H3, and H4) form an octamer, around which approximately 146 bp
            of DNA is wrapped in repeating units, called nucleosomes. The
            linker histone, H1, interacts with linker DNA between nucleosomes
            and functions in the compaction of chromatin into higher order
            structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H2A
            family. Transcripts from this gene lack polyA tails but instead
            contain a palindromic termination element. [provided by RefSeq, Aug
            2015].
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC139479.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-522               BC139479.1         1-522
FEATURES             Location/Qualifiers
     source          1..522
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 8.14 cM"
     gene            1..522
                     /gene="H2ac12"
                     /gene_synonym="Hist1h2ah"
                     /note="H2A clustered histone 12"
                     /db_xref="GeneID:319168"
                     /db_xref="MGI:MGI:2448295"
     exon            1..522
                     /gene="H2ac12"
                     /gene_synonym="Hist1h2ah"
                     /inference="alignment:Splign:2.1.0"
     CDS             92..478
                     /gene="H2ac12"
                     /gene_synonym="Hist1h2ah"
                     /note="histone 1, H2ah; histone cluster 1, H2ah"
                     /codon_start=1
                     /product="histone H2A type 1-H"
                     /protein_id="NP_783590.1"
                     /db_xref="CCDS:CCDS26304.1"
                     /db_xref="GeneID:319168"
                     /db_xref="MGI:MGI:2448295"
                     /translation="MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERV
                     GAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVT
                     IAQGGVLPNIQAVLLPKKTESHHKAK"
     polyA_site      522
                     /gene="H2ac12"
                     /gene_synonym="Hist1h2ah"
                     /note="major polyA site"
ORIGIN      
        1 gcgccctggc ttgactataa aaatctacag agtttccctt tgtttctgct gtttagctaa
       61 cgcttaccag ggaagtttta agttgtacaa tatgtctgga cgcggtaagc agggcggcaa
      121 ggctcgcgcc aaggccaaga cccgctcctc ccgggccggc ctgcagttcc ccgtgggccg
      181 cgtgcaccgg ctgctccgca agggcaacta ctcggagcgc gtgggcgccg gcgccccggt
      241 gtacctggcg gccgtgctgg agtacctgac ggccgagatc ctggagctgg cgggcaacgc
      301 ggcccgcgac aacaagaaga cgcgcatcat cccgcgccac ctgcagctgg ccatccgcaa
      361 cgacgaggag ctcaacaagc tgctgggccg cgtgaccatc gcgcagggcg gcgtcctgcc
      421 caacatccag gccgtgctgc tgcccaagaa gaccgagagc caccacaagg ccaagtgaag
      481 caggtttcaa tatctcccaa aggctctttt cagagccaca ca
//
