LOCUS       NM_175661                504 bp    mRNA    linear   ROD 15-FEB-2024
DEFINITION  Mus musculus H2A clustered histone 10 (H2ac10), mRNA.
ACCESSION   NM_175661
VERSION     NM_175661.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 504)
  AUTHORS   Ancelin,K., Lange,U.C., Hajkova,P., Schneider,R., Bannister,A.J.,
            Kouzarides,T. and Surani,M.A.
  TITLE     Blimp1 associates with Prmt5 and directs histone arginine
            methylation in mouse germ cells
  JOURNAL   Nat Cell Biol 8 (6), 623-630 (2006)
   PUBMED   16699504
REFERENCE   2  (bases 1 to 504)
  AUTHORS   Fang,J., Chen,T., Chadwick,B., Li,E. and Zhang,Y.
  TITLE     Ring1b-mediated H2A ubiquitination associates with inactive X
            chromosomes and is involved in initiation of X inactivation
  JOURNAL   J Biol Chem 279 (51), 52812-52815 (2004)
   PUBMED   15509584
REFERENCE   3  (bases 1 to 504)
  AUTHORS   de Napoles,M., Mermoud,J.E., Wakao,R., Tang,Y.A., Endoh,M.,
            Appanah,R., Nesterova,T.B., Silva,J., Otte,A.P., Vidal,M.,
            Koseki,H. and Brockdorff,N.
  TITLE     Polycomb group proteins Ring1A/B link ubiquitylation of histone H2A
            to heritable gene silencing and X inactivation
  JOURNAL   Dev Cell 7 (5), 663-676 (2004)
   PUBMED   15525528
REFERENCE   4  (bases 1 to 504)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   5  (bases 1 to 504)
  AUTHORS   Sittman,D.B., Graves,R.A. and Marzluff,W.F.
  TITLE     Structure of a cluster of mouse histone genes
  JOURNAL   Nucleic Acids Res 11 (19), 6679-6697 (1983)
   PUBMED   6314253
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL592149.8.
            
            On Jun 19, 2019 this sequence version replaced NM_175661.2.
            
            Summary: Histones are basic nuclear proteins that are responsible
            for the nucleosome structure of the chromosomal fiber in
            eukaryotes. This structure consists of approximately 146 bp of DNA
            wrapped around a nucleosome, an octamer composed of pairs of each
            of the four core histones (H2A, H2B, H3, and H4). The chromatin
            fiber is further compacted through the interaction of a linker
            histone, H1, with the DNA between the nucleosomes to form higher
            order chromatin structures. This gene is intronless and encodes a
            replication-dependent histone that is a member of the histone H2A
            family. Transcripts from this gene lack polyA tails; instead, they
            contain a palindromic termination element. [provided by RefSeq, Aug
            2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC125011.1, SRR7345562.4415816.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-504               AL592149.8         14477-14980
FEATURES             Location/Qualifiers
     source          1..504
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 9.77 cM"
     gene            1..504
                     /gene="H2ac10"
                     /gene_synonym="H2a-221; Hist1h2af"
                     /note="H2A clustered histone 10"
                     /db_xref="GeneID:319173"
                     /db_xref="MGI:MGI:2448309"
     exon            1..504
                     /gene="H2ac10"
                     /gene_synonym="H2a-221; Hist1h2af"
                     /inference="alignment:Splign:2.1.0"
     CDS             37..429
                     /gene="H2ac10"
                     /gene_synonym="H2a-221; Hist1h2af"
                     /note="histone H2a (aa 92-128); histone 1, H2af; histone
                     cluster 1, H2af"
                     /codon_start=1
                     /product="histone H2A type 1-F"
                     /protein_id="NP_783592.1"
                     /db_xref="CCDS:CCDS26341.1"
                     /db_xref="GeneID:319173"
                     /db_xref="MGI:MGI:2448309"
                     /translation="MSGRGKQGGKARAKAKTRSSRAGLQFPVGRVHRLLRKGNYSERV
                     GAGAPVYLAAVLEYLTAEILELAGNAARDNKKTRIIPRHLQLAIRNDEELNKLLGRVT
                     IAQGGVLPNIQAVLLPKKTESHHKPKGK"
ORIGIN      
        1 atacgctgaa cagatcctga cagcaaggta cctacaatgt ctggacgcgg caaacagggt
       61 ggcaaggctc gcgccaaggc caagacccgc tcctcccggg ccggcctgca gttccccgtg
      121 ggccgcgtgc accggctgct ccgcaagggc aactactcgg agcgcgtggg cgccggcgcc
      181 ccggtgtacc tggcggccgt gctggagtac ctgacggccg agatcctgga gctggcgggc
      241 aacgcggccc gcgacaacaa gaagacgcgc atcatcccgc gccacctgca gctggccatc
      301 cgcaacgacg aggagctcaa caagctgttg ggccgcgtga ccatcgcgca gggcggcgtc
      361 ctgcccaaca tccaggccgt gctgctgccc aagaagaccg agagccacca taagcccaag
      421 ggaaagtaag ccagtgagct aagttttttt tttttttttt tttttttttt aaacaaaacc
      481 caaaggctct tttcagagcc acca
//
