LOCUS       NM_001201460            1539 bp    mRNA    linear   ROD 03-APR-2024
DEFINITION  Mus musculus histocompatibility 2, Q region locus 9 (H2-Q9),
            transcript variant 1, mRNA.
ACCESSION   NM_001201460 XM_003085126 XM_003085127 XM_003085128 XM_003085190
            XM_003085191 XM_003085192 XM_003085193
VERSION     NM_001201460.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1539)
  AUTHORS   Martinez-Naves,E., Lafuente,E.M. and Reche,P.A.
  TITLE     Recognition of the ligand-type specificity of classical and
            non-classical MHC I proteins
  JOURNAL   FEBS Lett 585 (21), 3478-3484 (2011)
   PUBMED   22001201
REFERENCE   2  (bases 1 to 1539)
  AUTHORS   Swanson,P.A. 2nd, Pack,C.D., Hadley,A., Wang,C.R., Stroynowski,I.,
            Jensen,P.E. and Lukacher,A.E.
  TITLE     An MHC class Ib-restricted CD8 T cell response confers antiviral
            immunity
  JOURNAL   J Exp Med 205 (7), 1647-1657 (2008)
   PUBMED   18541714
REFERENCE   3  (bases 1 to 1539)
  AUTHORS   Ohtsuka,M., Inoko,H., Kulski,J.K. and Yoshimura,S.
  TITLE     Major histocompatibility complex (Mhc) class Ib gene duplications,
            organization and expression patterns in mouse strain C57BL/6
  JOURNAL   BMC Genomics 9, 178 (2008)
   PUBMED   18416856
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1539)
  AUTHORS   Chiang,E.Y. and Stroynowski,I.
  TITLE     The role of structurally conserved class I MHC in tumor rejection:
            contribution of the Q8 locus
  JOURNAL   J Immunol 177 (4), 2123-2130 (2006)
   PUBMED   16887971
  REMARK    GeneRIF: During primary and secondary rejection of tumors, Q9 is
            recognized by cross-reactive antitumor cytotoxic T cells, has
            overlapping peptide-binding motifs, and is assembled via the
            transporter associated with the antigen processing pathway.
REFERENCE   5  (bases 1 to 1539)
  AUTHORS   Nishimura,M., Yokoi,N., Miki,T., Horikawa,Y., Yoshioka,H.,
            Takeda,J., Ohara,O. and Seino,S.
  TITLE     Construction of a multi-functional cDNA library specific for mouse
            pancreatic islets and its application to microarray
  JOURNAL   DNA Res 11 (5), 315-323 (2004)
   PUBMED   15747579
REFERENCE   6  (bases 1 to 1539)
  AUTHORS   Wu,L., Exley,G.E. and Warner,C.M.
  TITLE     Differential expression of Ped gene candidates in preimplantation
            mouse embryos
  JOURNAL   Biol Reprod 59 (4), 941-952 (1998)
   PUBMED   9746747
REFERENCE   7  (bases 1 to 1539)
  AUTHORS   Watts,S., Davis,A.C., Gaut,B., Wheeler,C., Hill,L. and
            Goodenow,R.S.
  TITLE     Organization and structure of the Qa genes of the major
            histocompatibility complex of the C3H mouse: implications for Qa
            function and class I evolution
  JOURNAL   EMBO J 8 (6), 1749-1759 (1989)
   PUBMED   2767053
REFERENCE   8  (bases 1 to 1539)
  AUTHORS   Lyon,M.F., Zenthon,J., Evans,E.P., Burtenshaw,M.D. and
            Willison,K.R.
  TITLE     Extent of the mouse t complex and its inversions shown by in situ
            hybridization
  JOURNAL   Immunogenetics 27 (5), 375-382 (1988)
   PUBMED   3356450
REFERENCE   9  (bases 1 to 1539)
  AUTHORS   O'Neill,A.E., Reid,K., Garberi,J.C., Karl,M. and Flaherty,L.
  TITLE     Extensive deletions in the Q region of the mouse major
            histocompatibility complex
  JOURNAL   Immunogenetics 24 (6), 368-373 (1986)
   PUBMED   3025084
REFERENCE   10 (bases 1 to 1539)
  AUTHORS   Devlin,J.J., Weiss,E.H., Paulson,M. and Flavell,R.A.
  TITLE     Duplicated gene pairs and alleles of class I genes in the Qa2
            region of the murine major histocompatibility complex: a comparison
  JOURNAL   EMBO J 4 (12), 3203-3207 (1985)
   PUBMED   3004940
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY197645.1, AY989883.1, CN717653.1 and BP762043.1.
            
            On or before Jan 22, 2011 this sequence version replaced
            XM_003085127.1, XM_003085128.1, XM_003085192.1, XM_003085126.1,
            XM_003085190.1, XM_003085191.1, XM_003085193.1.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN00849375 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on expression, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-49                BY197645.1         2-50
            50-896              AY989883.1         1-847
            897-1050            CN717653.1         468-621
            1051-1394           AY989883.1         1002-1345
            1395-1539           BP762043.1         1-145               c
FEATURES             Location/Qualifiers
     source          1..1539
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17"
     gene            1..1539
                     /gene="H2-Q9"
                     /gene_synonym="H-2Q9; Ped; Qa-2; Qa-9; Qa9"
                     /note="histocompatibility 2, Q region locus 9"
                     /db_xref="GeneID:110558"
                     /db_xref="MGI:MGI:95938"
     exon            1..118
                     /gene="H2-Q9"
                     /gene_synonym="H-2Q9; Ped; Qa-2; Qa-9; Qa9"
                     /inference="alignment:Splign:2.1.0"
     CDS             55..1059
                     /gene="H2-Q9"
                     /gene_synonym="H-2Q9; Ped; Qa-2; Qa-9; Qa9"
                     /note="isoform 1 precursor is encoded by transcript
                     variant 1; H-2 class I histocompatibility antigen, Q9
                     alpha chain"
                     /codon_start=1
                     /product="H-2 class I histocompatibility antigen, Q9 alpha
                     chain isoform 1 precursor"
                     /protein_id="NP_001188389.1"
                     /db_xref="GeneID:110558"
                     /db_xref="MGI:MGI:95938"
                     /translation="MALTMLLLLVAAALTLIETRAGQHSLQYFHTAVSRPGLGEPWFI
                     SVGYVDDTQFVRFDSDAENPRMEPRARWMEQEGPEYWERETQIAKGHEQSFRGSLRTA
                     QSYYNQSKGGSHTLQWMYGCDMGSDGRLLRGYLQFAYEGRDYIALNEDLKTWTAVDMA
                     AQITRRKWEQAGIAEKDQAYLEGTCMQSLRRYLELGKETLLRTDPPKAHVTHHPRSYG
                     AVTLRCWALGFYPADITLTWQLNGEELTQDMELVETRPAGDGTFQKWASVVVPLGKEQ
                     NYTCHVNHEGLPEPLTLRWGRWEPPPYTVSNMATIAVVVDLGAVAIIGAVVAFVMNRR
                     "
     exon            119..388
                     /gene="H2-Q9"
                     /gene_synonym="H-2Q9; Ped; Qa-2; Qa-9; Qa9"
                     /inference="alignment:Splign:2.1.0"
     exon            389..664
                     /gene="H2-Q9"
                     /gene_synonym="H-2Q9; Ped; Qa-2; Qa-9; Qa9"
                     /inference="alignment:Splign:2.1.0"
     exon            665..949
                     /gene="H2-Q9"
                     /gene_synonym="H-2Q9; Ped; Qa-2; Qa-9; Qa9"
                     /inference="alignment:Splign:2.1.0"
     exon            950..1066
                     /gene="H2-Q9"
                     /gene_synonym="H-2Q9; Ped; Qa-2; Qa-9; Qa9"
                     /inference="alignment:Splign:2.1.0"
     exon            1067..1099
                     /gene="H2-Q9"
                     /gene_synonym="H-2Q9; Ped; Qa-2; Qa-9; Qa9"
                     /inference="alignment:Splign:2.1.0"
     exon            1100..1521
                     /gene="H2-Q9"
                     /gene_synonym="H-2Q9; Ped; Qa-2; Qa-9; Qa9"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gtaaagtcca cgctgcccac aggagtcagt cgaccggaat cccccagggg agcaatggct
       61 ctaacaatgc tgctcttgct ggtggcggcc gccctgaccc tgatcgagac ccgcgcgggc
      121 caacactcgc tgcaatattt ccacaccgct gtgtcccggc ccggcctcgg ggagccctgg
      181 ttcatctctg tcggctacgt ggacgacacg cagttcgtgc gcttcgacag cgatgcggaa
      241 aatccgagga tggagccgcg ggcgcggtgg atggagcagg aggggccgga gtattgggag
      301 cgggagacac agatcgccaa gggccatgag cagagtttcc gagggagcct gaggaccgca
      361 cagagctact acaaccagag caagggcggc tctcacacac tccagtggat gtatggctgt
      421 gacatggggt ccgacgggcg cctcctccgc gggtacctgc agttcgccta tgaaggccgc
      481 gattacatcg ccctgaacga agacctgaaa acgtggacgg cggtggacat ggcggcacag
      541 atcacccgac gcaagtggga gcaggctggt attgcagaga aagaccaggc ctacctggag
      601 ggcacgtgca tgcagtcgct ccgcagatac ctggagctcg ggaaggagac gctgctgcgc
      661 acagatcccc caaaggcaca tgtgacccat caccccaggt cttatggtgc tgtcaccctg
      721 aggtgctggg ccctgggctt ctaccctgct gacatcaccc tgacttggca gttgaatggg
      781 gaggagctga cccaggacat ggagcttgtg gagaccaggc ctgcagggga tggaaccttc
      841 cagaagtggg catctgtggt ggtgcctctt gggaaggagc agaattacac atgccatgtg
      901 aaccatgagg ggctgcctga gccccttacc ctgagatggg ggagatggga gcctcctcca
      961 tacactgtct ccaacatggc gaccattgct gttgtggttg accttggagc tgtggccatc
     1021 attggagctg tggtggcttt tgtgatgaat aggaggtgaa acacaggtgg acaaggaggg
     1081 gactgtgctc cagctccagc atgaagacag ctgcctggac tgcactgagt gacagacgat
     1141 gtgttcatgt ctctcctgtg acatccagag ccctcagttc tctttagaca acagtgtctc
     1201 atgttccctg tgagcctatg gactcaatgt gaggaactgt ggagcccagc ctgccctgca
     1261 cacctggacc ctgtccctgc actgccctgt tcccttccac agccaacctt cctgttccag
     1321 ccaaacactg ggtacatcta catcctgtca gctccatgct gccccgagct ccagctccat
     1381 actttcacac gaagagtatg tgaccttgat tgttatcatc ttgagctgag ggttgattgc
     1441 ttgttaattt aatggttgag aatacttagc atttttctct tttttaaaaa aataaataaa
     1501 tggcagatgg agaacctttc aaaaaaaaaa aaaaaaaaa
//
