LOCUS       NM_001115075            1199 bp    mRNA    linear   ROD 01-MAY-2024
DEFINITION  Mus musculus histocompatibility 2, M region locus 5 (H2-M5),
            transcript variant 1, mRNA.
ACCESSION   NM_001115075 XM_001474316 XM_903477 XM_908038 XM_993503
VERSION     NM_001115075.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1199)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1199)
  AUTHORS   Ingham,N.J., Pearson,S.A., Vancollie,V.E., Rook,V., Lewis,M.A.,
            Chen,J., Buniello,A., Martelletti,E., Preite,L., Lam,C.C.,
            Weiss,F.D., Powis,Z., Suwannarat,P., Lelliott,C.J., Dawson,S.J.,
            White,J.K. and Steel,K.P.
  TITLE     Mouse screen reveals multiple new genes underlying mouse and human
            hearing loss
  JOURNAL   PLoS Biol 17 (4), e3000194 (2019)
   PUBMED   30973865
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1199)
  AUTHORS   Ohtsuka,M., Inoko,H., Kulski,J.K. and Yoshimura,S.
  TITLE     Major histocompatibility complex (Mhc) class Ib gene duplications,
            organization and expression patterns in mouse strain C57BL/6
  JOURNAL   BMC Genomics 9, 178 (2008)
   PUBMED   18416856
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1199)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   5  (bases 1 to 1199)
  AUTHORS   Jones,E.P., Kumanovics,A., Yoshino,M. and Fischer Lindahl,K.
  TITLE     Mhc class I and non-class I gene organization in the proximal H2-M
            region of the mouse
  JOURNAL   Immunogenetics 49 (3), 183-195 (1999)
   PUBMED   9914332
REFERENCE   6  (bases 1 to 1199)
  AUTHORS   Arepalli,S.R., Jones,E.P., Howcroft,T.K., Carlo,I., Wang,C.,
            Lindahl,K.F., Singer,D.S. and Rudikoff,S.
  TITLE     Characterization of two class I genes from the H2-M region:
            evidence for a new subfamily
  JOURNAL   Immunogenetics 47 (3), 264-271 (1998)
   PUBMED   9435345
REFERENCE   7  (bases 1 to 1199)
  AUTHORS   Jones,E.P., Xiao,H., Schultz,R.A., Flaherty,L., Trachtulec,Z.,
            Vincek,V., Larin,Z., Lehrach,H. and Lindahl,K.F.
  TITLE     MHC class I gene organization in > 1.5-Mb YAC contigs from the H2-M
            region
  JOURNAL   Genomics 27 (1), 40-51 (1995)
   PUBMED   7665183
REFERENCE   8  (bases 1 to 1199)
  AUTHORS   Pham-Dinh,D., Jones,E.P., Pitiot,G., Della Gaspera,B., Daubas,P.,
            Mallet,J., Le Paslier,D., Fischer Lindahl,K. and Dautigny,A.
  TITLE     Physical mapping of the human and mouse MOG gene at the distal end
            of the MHC class Ib region
  JOURNAL   Immunogenetics 42 (5), 386-391 (1995)
   PUBMED   7590972
REFERENCE   9  (bases 1 to 1199)
  AUTHORS   Pham-Dinh,D., Mattei,M.G., Nussbaum,J.L., Roussel,G.,
            Pontarotti,P., Roeckel,N., Mather,I.H., Artzt,K., Lindahl,K.F. and
            Dautigny,A.
  TITLE     Myelin/oligodendrocyte glycoprotein is a member of a subset of the
            immunoglobulin superfamily encoded within the major
            histocompatibility complex
  JOURNAL   Proc Natl Acad Sci U S A 90 (17), 7990-7994 (1993)
   PUBMED   8367453
REFERENCE   10 (bases 1 to 1199)
  AUTHORS   Wang,C.R. and Lindahl,K.F.
  TITLE     Organization and structure of the H-2M4-M8 class I genes in the
            mouse major histocompatibility complex
  JOURNAL   Immunogenetics 38 (4), 258-271 (1993)
   PUBMED   8319975
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CR956641.9 and AB359228.2.
            
            On Feb 22, 2019 this sequence version replaced NM_001115075.1.
            
            Transcript Variant: This variant (1) represents the protein-coding
            transcript.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AB359228.2 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN01164132,
                                           SAMN01164134 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 5' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-29                CR956641.9         28466-28494
            30-1199             AB359228.2         1-1170
FEATURES             Location/Qualifiers
     source          1..1199
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 19.16 cM"
     gene            1..1199
                     /gene="H2-M5"
                     /gene_synonym="CRW2; D130003B22Rik; H-2M5"
                     /note="histocompatibility 2, M region locus 5"
                     /db_xref="GeneID:240095"
                     /db_xref="MGI:MGI:95917"
     exon            1..105
                     /gene="H2-M5"
                     /gene_synonym="CRW2; D130003B22Rik; H-2M5"
                     /inference="alignment:Splign:2.1.0"
     CDS             30..1076
                     /gene="H2-M5"
                     /gene_synonym="CRW2; D130003B22Rik; H-2M5"
                     /note="MHC classIb protein M5; MHC class I like protein
                     M5"
                     /codon_start=1
                     /product="histocompatibility 2, M region locus 5
                     precursor"
                     /protein_id="NP_001108547.1"
                     /db_xref="CCDS:CCDS50105.1"
                     /db_xref="GeneID:240095"
                     /db_xref="MGI:MGI:95917"
                     /translation="MRSPALSTLLSLLLTGALALTLVRAGIHSLQFFATTMTQPGLRE
                     HSFIFVVFVDDTQFLCYNNKGKNQRMEPRALWVKQMGPEYWEQQTRTVKVIEKIALVN
                     LQEAMDIYNHSKDGSHVFQCVYGCEVGPDGLFLRGHEKHAYDGRDYLTLSPDLHSWVA
                     GDTAAQITLRRWEKSGVSEQRQSFLKGECVESLRTYLEIGKETLLRTDPPKAHVTHHP
                     RPEGEVTLRCWALGFYPANIILTWQWDEEDLTQDMDLIETRPAGDGTFQKWASVVVPS
                     GEEQRYTCHVQHEGLTQPLVLKWDPSKHTIPIMGITVGLLLFGVVFTGAVVAIVMRKR
                     KGFQIIILKTFLKG"
     exon            106..375
                     /gene="H2-M5"
                     /gene_synonym="CRW2; D130003B22Rik; H-2M5"
                     /inference="alignment:Splign:2.1.0"
     exon            376..651
                     /gene="H2-M5"
                     /gene_synonym="CRW2; D130003B22Rik; H-2M5"
                     /inference="alignment:Splign:2.1.0"
     exon            652..927
                     /gene="H2-M5"
                     /gene_synonym="CRW2; D130003B22Rik; H-2M5"
                     /inference="alignment:Splign:2.1.0"
     exon            928..1035
                     /gene="H2-M5"
                     /gene_synonym="CRW2; D130003B22Rik; H-2M5"
                     /inference="alignment:Splign:2.1.0"
     exon            1036..1199
                     /gene="H2-M5"
                     /gene_synonym="CRW2; D130003B22Rik; H-2M5"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 agtccctcta gaccttctaa acacggagga tgagaagccc tgcgctctct accctcctat
       61 ccttgctgct caccggagct ttggccttga ccctggttcg cgcaggcatc cattccttgc
      121 agttttttgc caccaccatg acccagcctg gtttgaggga gcattccttc atctttgtcg
      181 tcttcgtgga cgacacacag ttcctgtgct acaacaataa ggggaaaaat cagagaatgg
      241 agccacgcgc tctgtgggtg aagcagatgg ggccagagta ttgggaacag cagaccagga
      301 ctgtcaaggt cattgagaag attgccctag tgaatttgca ggaggccatg gacatctaca
      361 accacagcaa ggatggctct cacgtctttc agtgtgtgta tggctgcgaa gtggggccag
      421 atggactctt cctccgtggg catgagaagc acgcatacga cggccgcgat tacctcaccc
      481 taagcccgga cctgcactcc tgggtcgcag gcgacacagc tgcgcagatc acgctgcgca
      541 ggtgggagaa gtctggtgtc tctgagcaaa ggcaatcctt cttgaagggc gagtgtgtgg
      601 agtcgctccg cacatacctg gagataggga aggagactct gctaagaaca gatcctccca
      661 aggcacatgt gacccatcac cccagacctg aaggtgaagt caccctgagg tgctgggccc
      721 tgggcttcta ccctgctaac atcatcctga cctggcagtg ggatgaggaa gacctgactc
      781 aggacatgga cctcattgag accagacctg caggggatgg gaccttccag aagtgggcat
      841 ctgtggtggt accttctgga gaggaacaga gatacacatg tcatgtgcaa catgaggggc
      901 taacccagcc ccttgttcta aaatgggacc cttctaagca caccattccc atcatgggaa
      961 tcactgttgg cctgcttctc tttggagttg tgtttactgg agctgtggtt gccatagtga
     1021 tgaggaagag gaaaggtttt cagataataa ttctaaaaac attcctgaag ggctgaaccc
     1081 aggaattctg ctaggatttc ccatcctgcc gctctcccat ctttttattc ccacagatgg
     1141 aaaaggatga gttactcaat ctattctaaa agctcacttt tcccatttta cttccctcc
//
