LOCUS       NM_001347387            1432 bp    mRNA    linear   ROD 28-SEP-2022
DEFINITION  Mus musculus histocompatibility 2, M region locus 2 (H2-M2), mRNA.
ACCESSION   NM_001347387 XM_006523682
VERSION     NM_001347387.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1432)
  AUTHORS   Frederico B, Martins I, Chapela D, Gasparrini F, Chakravarty P,
            Ackels T, Piot C, Almeida B, Carvalho J, Ciccarelli A, Peddie CJ,
            Rogers N, Briscoe J, Guillemot F, Schaefer AT, Saude L and Reis E
            Sousa C.
  TITLE     DNGR-1-tracing marks an ependymal cell subset with
            damage-responsive neural stem cell potential
  JOURNAL   Dev Cell 57 (16), 1957-1975 (2022)
   PUBMED   35998585
REFERENCE   2  (bases 1 to 1432)
  AUTHORS   Cichon MA, Klas K, Buchberger M, Hammer M, Sere K, Zenke M,
            Tschachler E and Elbe-Burger A.
  TITLE     Distinct Distribution of RTN1A in Immune Cells in Mouse Skin and
            Lymphoid Organs
  JOURNAL   Front Cell Dev Biol 8, 608876 (2021)
   PUBMED   33542915
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 1432)
  AUTHORS   Ohtsuka M, Inoko H, Kulski JK and Yoshimura S.
  TITLE     Major histocompatibility complex (Mhc) class Ib gene duplications,
            organization and expression patterns in mouse strain C57BL/6
  JOURNAL   BMC Genomics 9, 178 (2008)
   PUBMED   18416856
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1432)
  AUTHORS   Moore YF, Lambracht-Washington D, Tabaczewski P and Fischer Lindahl
            K.
  TITLE     Murine MHC class Ib gene, H2-M2, encodes a conserved
            surface-expressed glycoprotein
  JOURNAL   Immunogenetics 56 (1), 1-11 (2004)
   PUBMED   15045471
  REMARK    GeneRIF: H2-M2 is a conserved mouse class Ib gene that is
            translated to a surface-expressed MHC class I molecule
REFERENCE   5  (bases 1 to 1432)
  AUTHORS   Gunther E and Walter L.
  TITLE     Comparative genomic aspects of rat, mouse and human MHC class I
            gene regions
  JOURNAL   Cytogenet Cell Genet 91 (1-4), 107-112 (2000)
   PUBMED   11173841
  REMARK    Review article
REFERENCE   6  (bases 1 to 1432)
  AUTHORS   Jones EP, Xiao H, Schultz RA, Flaherty L, Trachtulec Z, Vincek V,
            Larin Z, Lehrach H and Lindahl KF.
  TITLE     MHC class I gene organization in > 1.5-Mb YAC contigs from the H2-M
            region
  JOURNAL   Genomics 27 (1), 40-51 (1995)
   PUBMED   7665183
REFERENCE   7  (bases 1 to 1432)
  AUTHORS   Pham-Dinh D, Mattei MG, Nussbaum JL, Roussel G, Pontarotti P,
            Roeckel N, Mather IH, Artzt K, Lindahl KF and Dautigny A.
  TITLE     Myelin/oligodendrocyte glycoprotein is a member of a subset of the
            immunoglobulin superfamily encoded within the major
            histocompatibility complex
  JOURNAL   Proc Natl Acad Sci U S A 90 (17), 7990-7994 (1993)
   PUBMED   8367453
REFERENCE   8  (bases 1 to 1432)
  AUTHORS   Himmelbauer H and Silver LM.
  TITLE     High-resolution comparative mapping of mouse chromosome 17
  JOURNAL   Genomics 17 (1), 110-120 (1993)
   PUBMED   8406442
REFERENCE   9  (bases 1 to 1432)
  AUTHORS   Richards S, Bucan M, Brorson K, Kiefer MC, Hunt SW 3rd, Lehrach H
            and Lindahl KF.
  TITLE     Genetic and molecular mapping of the Hmt region of mouse
  JOURNAL   EMBO J 8 (12), 3749-3757 (1989)
   PUBMED   2573520
REFERENCE   10 (bases 1 to 1432)
  AUTHORS   Brorson KA, Richards S, Hunt SW 3rd, Cheroutre H, Lindahl KF and
            Hood L.
  TITLE     Analysis of a new class I gene mapping to the Hmt region of the
            mouse
  JOURNAL   Immunogenetics 30 (4), 273-283 (1989)
   PUBMED   2793207
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CR974427.5.
            
            On Nov 24, 2016 this sequence version replaced XM_006523682.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY302213.1, AY302212.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849377
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-110               CR974427.5         140700-140809       c
            111-380             CR974427.5         140232-140501       c
            381-656             CR974427.5         139738-140013       c
            657-932             CR974427.5         138727-139002       c
            933-1432            CR974427.5         138106-138605       c
FEATURES             Location/Qualifiers
     source          1..1432
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 19.16 cM"
     gene            1..1432
                     /gene="H2-M2"
                     /gene_synonym="H-2M2; Thy19.4"
                     /note="histocompatibility 2, M region locus 2"
                     /db_xref="GeneID:14990"
                     /db_xref="MGI:MGI:95914"
     exon            1..110
                     /gene="H2-M2"
                     /gene_synonym="H-2M2; Thy19.4"
                     /inference="alignment:Splign:2.1.0"
     CDS             26..1057
                     /gene="H2-M2"
                     /gene_synonym="H-2M2; Thy19.4"
                     /codon_start=1
                     /product="histocompatibility 2, M region locus 2
                     precursor"
                     /protein_id="NP_001334316.1"
                     /db_xref="CCDS:CCDS84312.1"
                     /db_xref="GeneID:14990"
                     /db_xref="MGI:MGI:95914"
                     /translation="METSAFFTLLFTLYLLLGASLALAQTFKGSHSLRYFDIAVSRPG
                     LEETHYMTVGYVDDTEFVHFDNEAENPRFEPRVPWMEQMGQKYWDDQTRIAKAAEQQI
                     RVYFQKLRDYYNQSQNSSHTIQRMTGCYIGPDGHLLHAYRQFGYDGQDYLTLNEDLST
                     WTAADAAAEITRREWEATNVAEFWRVYLEGPCMVWLFKYLTVGNETLLRTEPPKAYVT
                     HHPRPEGDVTLRCWALGFYPSDIIMIWQRDGEDQTQDMDVIETRPAGDGTFQKWVAVV
                     VPSGKEQNYTCHVAHEGLPEPLTLRWSRPPQSFIFIIIVAVGLVLLGASVATLVMWKK
                     SSGGERGSL"
     exon            111..380
                     /gene="H2-M2"
                     /gene_synonym="H-2M2; Thy19.4"
                     /inference="alignment:Splign:2.1.0"
     exon            381..656
                     /gene="H2-M2"
                     /gene_synonym="H-2M2; Thy19.4"
                     /inference="alignment:Splign:2.1.0"
     exon            657..932
                     /gene="H2-M2"
                     /gene_synonym="H-2M2; Thy19.4"
                     /inference="alignment:Splign:2.1.0"
     exon            933..1432
                     /gene="H2-M2"
                     /gene_synonym="H-2M2; Thy19.4"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 gacagactcg ctccaaatcc agagaatgga gacttcagca ttcttcactc tcctcttcac
       61 tctctacctg ctgcttgggg cttcccttgc cctggcacag acctttaaag gatcccactc
      121 cttgcggtac ttcgacatcg cagtgtcaag acctggccta gaggagaccc actacatgac
      181 tgttggctat gtggatgaca cagagtttgt gcattttgac aatgaggctg agaatccgag
      241 gtttgagccc cgagtgcctt ggatggaaca gatgggacag aagtactggg atgaccagac
      301 acgcattgcg aaagctgcag aacagcagat tagagtgtac tttcagaaac tgcgagacta
      361 ctacaaccag agccagaaca gttctcacac catccaaagg atgactggct gctacattgg
      421 accagacggg cacctacttc acgcataccg tcagtttggt tatgatgggc aagattacct
      481 cactctgaat gaagatctga gcacctggac tgcagcagat gcggcagctg agatcacccg
      541 tagagagtgg gaggcaacta atgtggctga gttctggagg gtctacttgg agggcccttg
      601 catggtgtgg ctctttaaat acctgacagt gggaaatgag actctactgc gcacagagcc
      661 cccaaaggca tatgtgaccc atcaccccag acctgaaggt gatgtcaccc tgaggtgctg
      721 ggccctgggt ttctaccctt ctgacatcat catgatctgg caaagagatg gggaggacca
      781 gacccaggac atggatgtta ttgagaccag acctgcaggg gatggaacct tccagaagtg
      841 ggtagctgtg gtggtgcctt ctgggaagga gcagaattac acatgccatg tggctcatga
      901 gggactgcct gagcccctca ccctgagatg gagtagacct cctcagtctt tcattttcat
      961 cataatagtt gctgttggcc tggttctcct gggagcttca gtggctactc ttgtcatgtg
     1021 gaagaagagc tcgggtgggg aaaggggcag cctctgattt tttttttcca actgagagac
     1081 tctaagcccc agataagttt tctctgcctc cttgttggga aggagtgtgg cccattattc
     1141 ccaaagacac aattctgaat gtcataactg aaacatttta atctcaaaaa atcaaaatcc
     1201 ccaaaataca tttaaaaaag aaatacaaaa aaaagggaaa aaagtatcca aaccataaga
     1261 tagatttaaa gggatattta tacacacaca caagaaaagg aaaaagaaaa agaagaaaaa
     1321 ggaaacgaag aaaaagaaaa aggaaagaag gaaggaagga aggaaggaag gaaggaagga
     1381 aggaaggaag gaaggaagag aaatcacgat agaagagggg tctctgtatg aa
//
