LOCUS       NM_010377                735 bp    mRNA    linear   ROD 25-FEB-2025
DEFINITION  Mus musculus H1.6 linker histone, cluster member (H1f6), mRNA.
ACCESSION   NM_010377
VERSION     NM_010377.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 735)
  AUTHORS   Ito,M., Yun,Y., Kulkarni,D.S., Lee,S., Sandhu,S., Nunez,B., Hu,L.,
            Lee,K., Lim,N., Hirota,R.M., Prendergast,R., Huang,C., Huang,I. and
            Hunter,N.
  TITLE     Distinct and interdependent functions of three RING proteins
            regulate recombination during mammalian meiosis
  JOURNAL   Proc Natl Acad Sci U S A 122 (2), e2412961121 (2025)
   PUBMED   39761402
REFERENCE   2  (bases 1 to 735)
  AUTHORS   Yoshimura,S., Shimada,R., Kikuchi,K., Kawagoe,S., Abe,H.,
            Iisaka,S., Fujimura,S., Yasunaga,K.I., Usuki,S., Tani,N., Ohba,T.,
            Kondoh,E., Saio,T., Araki,K. and Ishiguro,K.I.
  TITLE     Atypical heat shock transcription factor HSF5 is critical for male
            meiotic prophase under non-stress conditions
  JOURNAL   Nat Commun 15 (1), 3330 (2024)
   PUBMED   38684656
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 735)
  AUTHORS   Feng,S., Wen,H., Liu,K., Xiong,M., Li,J., Gui,Y., Lv,C., Zhang,J.,
            Ma,X., Wang,X. and Yuan,S.
  TITLE     hnRNPH1 establishes Sertoli-germ cell crosstalk through cooperation
            with PTBP1 and AR, and is essential for male fertility in mice
  JOURNAL   Development 150 (3) (2023)
   PUBMED   36718792
REFERENCE   4  (bases 1 to 735)
  AUTHORS   Kazi,S., Castaneda,J.M., Savolainen,A., Xu,Y., Liu,N., Qiao,H.,
            Ramirez-Solis,R., Nozawa,K., Yu,Z., Matzuk,M.M. and
            Prunskaite-Hyyrylainen,R.
  TITLE     MRNIP interacts with sex body chromatin to support meiotic
            progression, spermatogenesis, and male fertility in mice
  JOURNAL   FASEB J 36 (9), e22479 (2022)
   PUBMED   35920200
REFERENCE   5  (bases 1 to 735)
  AUTHORS   Tanno,N., Takemoto,K., Takada-Horisawa,Y., Shimada,R., Fujimura,S.,
            Tani,N., Takeda,N., Araki,K. and Ishiguro,K.I.
  TITLE     FBXO47 is essential for preventing the synaptonemal complex from
            premature disassembly in mouse male meiosis
  JOURNAL   iScience 25 (4), 104008 (2022)
   PUBMED   35310947
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 735)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   7  (bases 1 to 735)
  AUTHORS   Wang,Z.F., Krasikov,T., Frey,M.R., Wang,J., Matera,A.G. and
            Marzluff,W.F.
  TITLE     Characterization of the mouse histone gene cluster on chromosome
            13: 45 histone genes in three patches spread over 1Mb
  JOURNAL   Genome Res 6 (8), 688-701 (1996)
   PUBMED   8858344
REFERENCE   8  (bases 1 to 735)
  AUTHORS   vanWert,J.M., Wolfe,S.A. and Grimes,S.R.
  TITLE     Testis-specific expression of the rat histone Hlt gene in
            transgenic mice
  JOURNAL   Biochemistry 34 (27), 8733-8743 (1995)
   PUBMED   7612613
REFERENCE   9  (bases 1 to 735)
  AUTHORS   Koppel,D.A., Wolfe,S.A., Fogelfeld,L.A., Merchant,P.S., Prouty,L.
            and Grimes,S.R.
  TITLE     Primate testicular histone H1t genes are highly conserved and the
            human H1t gene is located on chromosome 6
  JOURNAL   J Cell Biochem 54 (2), 219-230 (1994)
   PUBMED   8175896
REFERENCE   10 (bases 1 to 735)
  AUTHORS   Drabent,B., Bode,C. and Doenecke,D.
  TITLE     Structure and expression of the mouse testicular H1 histone gene
            (H1t)
  JOURNAL   Biochim Biophys Acta 1216 (2), 311-313 (1993)
   PUBMED   8241275
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL592149.8.
            
            On Feb 25, 2014 this sequence version replaced NM_010377.2.
            
            Summary: Histones are basic nuclear proteins responsible for
            nucleosome structure of the chromosomal fiber in eukaryotes. Two
            molecules of each of the four core histones (H2A, H2B, H3, and H4)
            form an octamer, around which approximately 146 bp of DNA is
            wrapped in repeating units, called nucleosomes. The linker histone,
            H1, interacts with linker DNA between nucleosomes and functions in
            the compaction of chromatin into higher order structures. This gene
            is intronless and encodes a replication-dependent histone that is a
            member of the histone H1 family. Transcripts from this gene lack
            polyA tails but instead contain a palindromic termination element
            [provided by RefSeq, Aug 2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: BC119307.1, SRR5189685.292842.1
                                        [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: full length.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-735               AL592149.8         176226-176960
FEATURES             Location/Qualifiers
     source          1..735
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 9.88 cM"
     gene            1..735
                     /gene="H1f6"
                     /gene_synonym="H1-6; H1.6; H1ft; H1t; Hist1h1t"
                     /note="H1.6 linker histone, cluster member"
                     /db_xref="GeneID:107970"
                     /db_xref="MGI:MGI:1888530"
     exon            1..735
                     /gene="H1f6"
                     /gene_synonym="H1-6; H1.6; H1ft; H1t; Hist1h1t"
                     /inference="alignment:Splign:2.1.0"
     CDS             56..685
                     /gene="H1f6"
                     /gene_synonym="H1-6; H1.6; H1ft; H1t; Hist1h1t"
                     /note="histone 1, H1t; testicular H1 histone; H1 histone
                     family, member T (testis-specific); histone cluster 1,
                     H1t"
                     /codon_start=1
                     /product="histone H1t"
                     /protein_id="NP_034507.2"
                     /db_xref="CCDS:CCDS26358.1"
                     /db_xref="GeneID:107970"
                     /db_xref="MGI:MGI:1888530"
                     /translation="MSETAPAASSTLVPAPVEEKPSSKRRGKKPGLAPARKPRGFSVS
                     KLIPEALSTSQERAGMSLAALKKALAAAGYDVEKNNSRIKLALKRLVNKGVLVQTKGT
                     GASGSFKLSKKAASGNDKGKGKKSASAKAKKMGLPRASRSPKSSKTKAVKKPKATPTK
                     ASGSGRKTKGAKGVQQRKSPAKARAANPNSGKAKMVMQKTDLRKAAGRK"
ORIGIN      
        1 actgttggct ctcctttagt tttcacttgg tgtagttctt gtccagctct tgaccatgtc
       61 ggaaacggct cctgcggcct caagtaccct tgttccagct cctgtggagg agaaaccttc
      121 atctaaaagg cgagggaaaa agcctggcct ggcccctgct cgcaaacctc ggggtttctc
      181 agtttccaag ctgattcctg aggccctttc cacatcgcag gaacgggcag gaatgtccct
      241 tgctgccctg aagaaagccc tggctgcggc tggttacgac gtggagaaga acaacagccg
      301 tatcaagctg gccctcaaga gacttgtgaa taaaggagtc ctggtgcaga ccaagggcac
      361 tggcgcctca ggctccttca agctcagtaa gaaggcggct tctgggaacg acaagggcaa
      421 gggcaagaaa tctgcttctg ccaaggctaa gaagatgggc ttgccccggg cctcgagatc
      481 tcccaagagt agcaagacca aggctgtcaa gaagccaaag gctacgccca caaaagcttc
      541 tgggagcgga aggaagacca aaggggccaa gggcgtgcag caacgtaaaa gccccgccaa
      601 agccagggca gcaaacccca attctgggaa ggcaaaaatg gtcatgcaga agaccgatct
      661 gaggaaggca gcagggagga agtgagtttc aaagccagtt ttcaaaaacc caaaggctct
      721 tttaagagcc actta
//
