LOCUS       NM_020034                794 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus H1.5 linker histone, cluster member (H1f5), mRNA.
ACCESSION   NM_020034
VERSION     NM_020034.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 794)
  AUTHORS   Izzo,A., Ziegler-Birling,C., Hill,P.W.S., Brondani,L., Hajkova,P.,
            Torres-Padilla,M.E. and Schneider,R.
  TITLE     Dynamic changes in H1 subtype composition during epigenetic
            reprogramming
  JOURNAL   J Cell Biol 216 (10), 3017-3028 (2017)
   PUBMED   28794128
REFERENCE   2  (bases 1 to 794)
  AUTHORS   Pan,C. and Fan,Y.
  TITLE     Role of H1 linker histones in mammalian development and stem cell
            differentiation
  JOURNAL   Biochim Biophys Acta 1859 (3), 496-509 (2016)
   PUBMED   26689747
  REMARK    Review article
REFERENCE   3  (bases 1 to 794)
  AUTHORS   Syed,S.H., Goutte-Gattat,D., Becker,N., Meyer,S., Shukla,M.S.,
            Hayes,J.J., Everaers,R., Angelov,D., Bednar,J. and Dimitrov,S.
  TITLE     Single-base resolution mapping of H1-nucleosome interactions and 3D
            organization of the nucleosome
  JOURNAL   Proc Natl Acad Sci U S A 107 (21), 9620-9625 (2010)
   PUBMED   20457934
REFERENCE   4  (bases 1 to 794)
  AUTHORS   Lu,X., Hamkalo,B., Parseghian,M.H. and Hansen,J.C.
  TITLE     Chromatin condensing functions of the linker histone C-terminal
            domain are mediated by specific amino acid composition and
            intrinsic protein disorder
  JOURNAL   Biochemistry 48 (1), 164-172 (2009)
   PUBMED   19072710
REFERENCE   5  (bases 1 to 794)
  AUTHORS   Lee,H., Quinn,J.C., Prasanth,K.V., Swiss,V.A., Economides,K.D.,
            Camacho,M.M., Spector,D.L. and Abate-Shen,C.
  TITLE     PIAS1 confers DNA-binding specificity on the Msx1 homeoprotein
  JOURNAL   Genes Dev 20 (7), 784-794 (2006)
   PUBMED   16600910
REFERENCE   6  (bases 1 to 794)
  AUTHORS   Marzluff,W.F., Gongidi,P., Woods,K.R., Jin,J. and Maltais,L.J.
  TITLE     The human and mouse replication-dependent histone genes
  JOURNAL   Genomics 80 (5), 487-498 (2002)
   PUBMED   12408966
REFERENCE   7  (bases 1 to 794)
  AUTHORS   Wang,Z.F., Sirotkin,A.M., Buchold,G.M., Skoultchi,A.I. and
            Marzluff,W.F.
  TITLE     The mouse histone H1 genes: gene organization and differential
            regulation
  JOURNAL   J Mol Biol 271 (1), 124-138 (1997)
   PUBMED   9300059
REFERENCE   8  (bases 1 to 794)
  AUTHORS   Kaludov,N.K., Pabon-Pena,L., Seavy,M., Robinson,G. and Hurt,M.M.
  TITLE     A mouse histone H1 variant, H1b, binds preferentially to a
            regulatory sequence within a mouse H3.2 replication-dependent
            histone gene
  JOURNAL   J Biol Chem 272 (24), 15120-15127 (1997)
   PUBMED   9182532
REFERENCE   9  (bases 1 to 794)
  AUTHORS   Wang,Z.F., Krasikov,T., Frey,M.R., Wang,J., Matera,A.G. and
            Marzluff,W.F.
  TITLE     Characterization of the mouse histone gene cluster on chromosome
            13: 45 histone genes in three patches spread over 1Mb
  JOURNAL   Genome Res 6 (8), 688-701 (1996)
   PUBMED   8858344
REFERENCE   10 (bases 1 to 794)
  AUTHORS   Drabent,B., Franke,K., Bode,C., Kosciessa,U., Bouterfa,H.,
            Hameister,H. and Doenecke,D.
  TITLE     Isolation of two murine H1 histone genes and chromosomal mapping of
            the H1 gene complement
  JOURNAL   Mamm Genome 6 (8), 505-511 (1995)
   PUBMED   8589518
COMMENT     REVIEWED REFSEQ: This record has been curated by NCBI staff. The
            reference sequence was derived from AL589651.8.
            
            On Feb 28, 2014 this sequence version replaced NM_020034.1.
            
            Summary: Histones are basic nuclear proteins responsible for
            nucleosome structure of the chromosomal fiber in eukaryotes. Two
            molecules of each of the four core histones (H2A, H2B, H3, and H4)
            form an octamer, around which approximately 146 bp of DNA is
            wrapped in repeating units, called nucleosomes. The linker histone,
            H1, interacts with linker DNA between nucleosomes and functions in
            the compaction of chromatin into higher order structures. This gene
            is intronless and encodes a replication-dependent histone that is a
            member of the histone H1 family. Transcripts from this gene lack
            polyA tails but instead contain a palindromic termination element.
            [provided by RefSeq, Sep 2015].
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript is intronless :: AK020117.1, CJ139745.1 [ECO:0000345]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria        :: based on single protein-coding
                                             transcript
            replication-dependent histone :: PMID: 12408966
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-794               AL589651.8         200822-201615       c
FEATURES             Location/Qualifiers
     source          1..794
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="13"
                     /map="13 7.97 cM"
     gene            1..794
                     /gene="H1f5"
                     /gene_synonym="H1-5; H1.5; H1B; H1s-3; Hist1h1b"
                     /note="H1.5 linker histone, cluster member"
                     /db_xref="GeneID:56702"
                     /db_xref="MGI:MGI:1861461"
     exon            1..794
                     /gene="H1f5"
                     /gene_synonym="H1-5; H1.5; H1B; H1s-3; Hist1h1b"
                     /inference="alignment:Splign:2.1.0"
     regulatory      760..765
                     /regulatory_class="polyA_signal_sequence"
                     /gene="H1f5"
                     /gene_synonym="H1-5; H1.5; H1B; H1s-3; Hist1h1b"
                     /note="hexamer: AACAAA"
     polyA_site      794
                     /gene="H1f5"
                     /gene_synonym="H1-5; H1.5; H1B; H1s-3; Hist1h1b"
                     /note="major polyA site"
ORIGIN      
        1 atcgcaaaat ttgctcttcg cgttagattt cttttagttt tctcgcaact agcaagcttt
       61 ttgttctcgc catgtctgag actgctcccg ctgagaccgc ggctccggct cctgtagaga
      121 agtctcccgc caagaagaag acaacgaaaa aagctggcgc ggcgaagcgc aaggccactg
      181 gccccccggt gtccgagctc atcactaagg ctgtttctgc ctctaaggag cgcggcggcg
      241 tgtccctgcc tgcccttaag aaggcactgg ctgctggtgg ctacgatgtg gagaagaaca
      301 acagccgcat caagcttggg ctcaagagtc tggtgagcaa gggtaccctg gtgcagacca
      361 agggcaccgg cgcctctggt tccttcaagc ttaacaagaa ggcggcttct ggcgaggcca
      421 agcccaaggc taagaagacc ggggctgcca aggccaagaa gcctgcaggt gctaccccta
      481 aaaagcctaa gaagactgcg ggggcaaaga agaccgtgaa gaaaactcca aagaaagcga
      541 agaagcctgc ggcggctgga gtgaagaaag ttgccaagag tcctaagaag gccaaggctg
      601 ctgccaagcc taaaaaagca gcaaagagcc cggccaagcc caaggcggtg aagtctaagg
      661 catccaaacc taaggttacc aagcctaaga ccgctaagcc taaggctgcc aaggccaaga
      721 aggctgtttc caaaaagaag taggtttgct tgcgacagca acaaagcccc aaaggctctt
      781 ttcagagcca ccta
//
