LOCUS       NM_010369               1827 bp    mRNA    linear   ROD 01-AUG-2024
DEFINITION  Mus musculus glycophorin A (Gypa), mRNA.
ACCESSION   NM_010369
VERSION     NM_010369.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1827)
  AUTHORS   Sangkhae,V., Yu,V., Coffey,R., O'Brien,K.O., Ganz,T. and Nemeth,E.
  TITLE     Erythroferrone contributes to iron mobilization for embryo
            erythropoiesis in iron-deficient mouse pregnancies
  JOURNAL   Am J Hematol 97 (10), 1348-1358 (2022)
   PUBMED   36071577
REFERENCE   2  (bases 1 to 1827)
  AUTHORS   Sinha,T., Lammerts van Bueren,K., Dickel,D.E., Zlatanova,I.,
            Thomas,R., Lizama,C.O., Xu,S.M., Zovein,A.C., Ikegami,K.,
            Moskowitz,I.P., Pollard,K.S., Pennacchio,L.A. and Black,B.L.
  TITLE     Differential Etv2 threshold requirement for endothelial and
            erythropoietic development
  JOURNAL   Cell Rep 39 (9), 110881 (2022)
   PUBMED   35649376
REFERENCE   3  (bases 1 to 1827)
  AUTHORS   Huang,Y.S., Delgadillo,L.F., Cyr,K.H., Kingsley,P.D., An,X.,
            McGrath,K.E., Mohandas,N., Conboy,J.G., Waugh,R.E., Wan,J. and
            Palis,J.
  TITLE     Circulating primitive erythroblasts establish a functional, protein
            4.1R-dependent cytoskeletal network prior to enucleating
  JOURNAL   Sci Rep 7 (1), 5164 (2017)
   PUBMED   28701737
  REMARK    Publication Status: Online-Only
REFERENCE   4  (bases 1 to 1827)
  AUTHORS   Burrill,D.R., Vernet,A., Collins,J.J., Silver,P.A. and Way,J.C.
  TITLE     Targeted erythropoietin selectively stimulates red blood cell
            expansion in vivo
  JOURNAL   Proc Natl Acad Sci U S A 113 (19), 5245-5250 (2016)
   PUBMED   27114509
REFERENCE   5  (bases 1 to 1827)
  AUTHORS   Ghanem,L.R., Kromer,A., Silverman,I.M., Chatterji,P., Traxler,E.,
            Penzo-Mendez,A., Weiss,M.J., Stanger,B.Z. and Liebhaber,S.A.
  TITLE     The Poly(C) Binding Protein Pcbp2 and Its Retrotransposed
            Derivative Pcbp1 Are Independently Essential to Mouse Development
  JOURNAL   Mol Cell Biol 36 (2), 304-319 (2015)
   PUBMED   26527618
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 1827)
  AUTHORS   Nemoto,Y., Terajima,M., Shoji,W. and Obinata,M.
  TITLE     Regulatory function of delta/YY-1 on the locus control region-like
            sequence of mouse glycophorin gene in erythroleukemia cells
  JOURNAL   J Biol Chem 271 (23), 13542-13548 (1996)
   PUBMED   8662744
REFERENCE   7  (bases 1 to 1827)
  AUTHORS   Mills,K.A., Mathews,K.D., Scherpbier-Heddema,T., Schelper,R.L.,
            Schmalzel,R., Bailey,H.L., Nadeau,J.H., Buetow,K.H. and Murray,J.C.
  TITLE     Genetic mapping near the myd locus on mouse chromosome 8
  JOURNAL   Mamm Genome 6 (4), 278-280 (1995)
   PUBMED   7613034
REFERENCE   8  (bases 1 to 1827)
  AUTHORS   Terajima,M., Matsui,Y., Copeland,N.G., Gilbert,D.J., Jenkins,N.A.
            and Obinata,M.
  TITLE     Structural organization of the mouse glycophorin A gene
  JOURNAL   J Biochem 116 (5), 1105-1110 (1994)
   PUBMED   7896738
REFERENCE   9  (bases 1 to 1827)
  AUTHORS   Gu,H., Planas,J., Gomez,R. and Wilson,D.J.
  TITLE     Full length mouse glycophorin gene constructed using recombinant
            polymerase chain reaction
  JOURNAL   Biochem Biophys Res Commun 177 (1), 202-208 (1991)
   PUBMED   2043106
REFERENCE   10 (bases 1 to 1827)
  AUTHORS   Matsui,Y., Natori,S. and Obinata,M.
  TITLE     Isolation of the cDNA clone for mouse glycophorin,
            erythroid-specific membrane protein
  JOURNAL   Gene 77 (2), 325-332 (1989)
   PUBMED   2753361
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK157851.1, AK162614.1 and BY595233.1.
            
            On Aug 5, 2006 this sequence version replaced NM_010369.2.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK162614.1, AK145998.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849388, SAMN00849390
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-17                AK157851.1         2-18
            18-1631             AK162614.1         3-1616
            1632-1827           BY595233.1         247-442
FEATURES             Location/Qualifiers
     source          1..1827
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="8"
                     /map="8 38.27 cM"
     gene            1..1827
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /note="glycophorin A"
                     /db_xref="GeneID:14934"
                     /db_xref="MGI:MGI:95880"
     exon            1..43
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /inference="alignment:Splign:2.1.0"
     CDS             10..516
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /codon_start=1
                     /product="glycophorin-A"
                     /protein_id="NP_034499.3"
                     /db_xref="CCDS:CCDS40399.1"
                     /db_xref="GeneID:14934"
                     /db_xref="MGI:MGI:95880"
                     /translation="MTESTAAVTTSGHSLTTTFHIPSSQHYQEEHSPSLSGSDSLLQI
                     TTPVVASTVGNPNQHSATMSTPAIHVSTYHTAPTEVSAAFEEQPVSPHIGGMPSPIQH
                     DFPALVMILIILGVMAGIIGTILLISYCISRMTKKSSVDIQSPEGGDNSVPLSSIEQT
                     PNEESSNV"
     exon            44..124
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /inference="alignment:Splign:2.1.0"
     exon            125..208
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /inference="alignment:Splign:2.1.0"
     exon            209..292
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /inference="alignment:Splign:2.1.0"
     exon            293..331
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /inference="alignment:Splign:2.1.0"
     exon            332..417
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /inference="alignment:Splign:2.1.0"
     exon            418..486
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /inference="alignment:Splign:2.1.0"
     exon            487..1827
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      689
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /note="major polyA site"
     regulatory      1376..1381
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /note="hexamer: AATAAA"
     polyA_site      1391
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /note="major polyA site"
     regulatory      1575..1580
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /note="hexamer: AATATA"
     polyA_site      1595
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
     regulatory      1601..1606
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /note="hexamer: AATAAA"
     polyA_site      1631
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
     regulatory      1792..1797
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
                     /note="hexamer: AATAAA"
     polyA_site      1818
                     /gene="Gypa"
                     /gene_synonym="CD235a; GPA"
ORIGIN      
        1 actcccagta tgaccgagag cacagctgct gtgacaacat caggtcattc tcttacaacc
       61 accttccata taccttcaag tcaacattac caagaagagc attcaccatc attgtcagga
      121 tcagattctc ttcttcaaat aaccactcct gtggtggctt caactgtagg taacccaaat
      181 cagcattcag caacaatgtc aacaccagct attcatgtct caacttatca cacggcccct
      241 actgaagtgt ctgctgcgtt tgaagaacag cctgtctcac cacacattgg aggaatgccg
      301 tcaccaattc aacacgattt tcctgcacta gtgatgatac tcataatttt gggcgtgatg
      361 gcagggatta tcggaactat ccttcttatc tcttactgta tcagccgaat gacaaagaaa
      421 agttcagttg acatccaatc tcctgagggt ggtgacaaca gtgtgccttt gagttctatt
      481 gagcagactc ctaatgaaga gtcctccaat gtttgaaaga cctcaaggaa aacaagactt
      541 caatcaatgg gaaaaataat cggctgtgtc agtaaattat gtaccttcct gagctacacc
      601 attgtaagaa gaaaatgcca cctttggagt ctgtgattca ctatggggat ggggaaactc
      661 tgttaattaa taactgatga tgaacaagag cttccttgta tgcttgattt tgctcgcaga
      721 aatttttgta actgcttgac tagatatttt actcaaaaat ttcaattgag tttgtgtgcc
      781 gtcctttaag gctgatgtat tcaactctgt tatggtttgt tcctggtgac atcacagaag
      841 ggcttttact gtctccatga aatccaagat tcctcatcgc ttcaacccca gagcccattt
      901 ttatttaatt taagtaaatt aaaagaccag taagtcttcc cgtgttcttc cttgccaggc
      961 aggcagcaca cagctctctt actgggaagg atgctttgcc aacactcaga aatgccacaa
     1021 acataaatgt atgtaaggac actcacagcc ctcattcagt gtgtaagtca atacaaaaag
     1081 tatttattat tttaaacagg aagttgcttt cttgaataat tcaaaataat ttgacaatgg
     1141 cacattgact ccttcagagt atggaccagt gtgtcatgtt gaaaagagaa gtttctggaa
     1201 ccactcagag taccccctaa ggataaaata taaaatataa aaataattaa ggccctttcc
     1261 ttgcagtgga aatcagacag taactactgt aactgcaagt gagaggcatg ggtgaaagcg
     1321 ttagtaactg ggttttcaac aaactggaac ccatccagtg gaagcttccc ttcttaataa
     1381 aactttgaac tcagaggctt tgtggctata ctgctgccgt tcctttgtag aaaaacttaa
     1441 gatactaaat gatttttaag aggacatgac tttaggaggg gtgggaggta gggggtggag
     1501 ctgggactgg caaaggaaga gagtaaggga tgaaaatgtt caaaatacat tgtatgaaat
     1561 tctcaagaat aaaaaatata ttttaaaaaa atcaatataa aataaaacct gtgactgtct
     1621 atttccaagt tgacaagagt ccatgtggct tcccttgctt tatgataact aagtaaataa
     1681 catatatgta catatctagt cttggaaaca aatctatttt taatatgttt tcttttttta
     1741 aaaaatctgc ctgtatgttc agagaatgtt ttatatttgc cacctattta aaataaaaga
     1801 atggcaataa aaagagaata tttgttg
//
