LOCUS       NM_198612               1826 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus glucoside xylosyltransferase 2 (Gxylt2), mRNA.
ACCESSION   NM_198612 XM_132702
VERSION     NM_198612.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1826)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from AC121925.2 and
            AC155648.14.
            
            On Nov 17, 2006 this sequence version replaced NM_198612.1.
            
            Sequence Note: The RefSeq transcript and protein were derived from
            genomic sequence to make the sequence consistent with the reference
            genome assembly. The genomic coordinates used for the transcript
            record were based on alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC049816.1, SRR7345562.1173807.1
                                           [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-391               AC121925.2         132454-132844
            392-581             AC121925.2         160901-161090
            582-713             AC121925.2         178118-178249
            714-965             AC155648.14        38812-39063
            966-1089            AC155648.14        42914-43037
            1090-1262           AC155648.14        53804-53976
            1263-1826           AC155648.14        60221-60784
FEATURES             Location/Qualifiers
     source          1..1826
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="6"
                     /map="6 46.9 cM"
     gene            1..1826
                     /gene="Gxylt2"
                     /gene_synonym="Glt8d4; Gm152"
                     /note="glucoside xylosyltransferase 2"
                     /db_xref="GeneID:232313"
                     /db_xref="MGI:MGI:2682940"
     exon            1..391
                     /gene="Gxylt2"
                     /gene_synonym="Glt8d4; Gm152"
                     /inference="alignment:Splign:2.1.0"
     CDS             111..1445
                     /gene="Gxylt2"
                     /gene_synonym="Glt8d4; Gm152"
                     /EC_number="2.4.2.42"
                     /note="glycosyltransferase 8 domain-containing protein 4;
                     glycosyltransferase 8 domain containing 4"
                     /codon_start=1
                     /product="glucoside xylosyltransferase 2"
                     /protein_id="NP_941014.1"
                     /db_xref="CCDS:CCDS20390.1"
                     /db_xref="GeneID:232313"
                     /db_xref="MGI:MGI:2682940"
                     /translation="MKLRSKAAALLLLALAVLLLALLSLRARRDPEPPGFPARPEAAP
                     QRRHAPVPTLPPEPRAFPGAAGRRSPRRQPPRLRPRAGRPRAASREKLARRPGETRSL
                     HSVPPELWIHLAVVACGNRLEETLVMLKSAVLFSHRKMRFHIFTEDALKPEFDKQLRQ
                     WPDSYTKKFEHRLYPITFSVGNPQEWKKLFKPCAAQRLFLPAILKDVDSLLYVDTDVL
                     FLRPVDDIWKLLRQFNSTQLAAMAPEHEIPKIGWYSRFARHPFYGSAGVNSGVMLMNL
                     TRIRNTQFKNSLIPAGLAWEEMLLPLYQKYKSAITWGDQDLLNIIFYYNPECLYVFPC
                     QWNYRPDHCMYGSNCKEAEREGVSVLHGNRGVYHDDKQPTFRALYEAIRDFPFQDNLF
                     QSMYYPLQLKFLETVHTLCGRIPQVFLKQIEKTMRRAYEKHVIIHMGPNPMS"
     exon            392..581
                     /gene="Gxylt2"
                     /gene_synonym="Glt8d4; Gm152"
                     /inference="alignment:Splign:2.1.0"
     exon            582..713
                     /gene="Gxylt2"
                     /gene_synonym="Glt8d4; Gm152"
                     /inference="alignment:Splign:2.1.0"
     exon            714..965
                     /gene="Gxylt2"
                     /gene_synonym="Glt8d4; Gm152"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1089
                     /gene="Gxylt2"
                     /gene_synonym="Glt8d4; Gm152"
                     /inference="alignment:Splign:2.1.0"
     exon            1090..1262
                     /gene="Gxylt2"
                     /gene_synonym="Glt8d4; Gm152"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1826
                     /gene="Gxylt2"
                     /gene_synonym="Glt8d4; Gm152"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1807..1812
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gxylt2"
                     /gene_synonym="Glt8d4; Gm152"
                     /note="hexamer: AATACA"
     polyA_site      1826
                     /gene="Gxylt2"
                     /gene_synonym="Glt8d4; Gm152"
                     /note="major polyA site"
ORIGIN      
        1 gccaccgcta gcttcgaccc tagtccgggg cgagccggcc tggacgctgc gccgccgcgg
       61 gcagcgatgc gcagagtgtc cgcgccgccc cggggccgcc gtgcggcacc atgaagctcc
      121 gcagcaaggc ggcagcgctg ctcctgctcg cgctggccgt gctgctgcta gcgctgctgt
      181 ccttgcgcgc ccgccgggac ccggagcccc ctgggttccc cgcgcgcccg gaggctgccc
      241 ctcagcgccg ccacgcgccg gtccccacgc tccctccgga gccccgcgcc ttccccggag
      301 ccgctggccg gcgctccccc aggcgccagc ccccacgtct gcgcccccga gcgggccgcc
      361 cgcgcgccgc cagccgcgag aagttggcga ggaggcctgg ggaaacgagg agcttgcact
      421 ctgtgccacc cgaactctgg attcacctgg ccgtggtggc ctgtggcaac cggctggagg
      481 aaactctggt catgctcaag tcagctgtgc ttttcagcca caggaagatg cgctttcaca
      541 tcttcacaga agatgctctg aagcccgagt ttgataaaca gttgcgccag tggcccgact
      601 cctatacaaa gaagtttgag cacagactct accctatcac attttccgtc ggaaaccctc
      661 aggaatggaa gaaactattc aaaccctgtg ccgcccagag gctctttctc ccggcgatct
      721 taaaggacgt ggactcgctt ctctacgtgg acactgacgt cctctttctg cggcctgtgg
      781 acgacatctg gaagcttctg aggcagttta actccaccca gcttgctgct atggccccag
      841 agcatgaaat cccgaagatc ggctggtaca gtcgctttgc ccggcatcct ttctacggct
      901 ctgccggggt taactccggg gtcatgctca tgaacttgac tcgcataaga aatacccagt
      961 tcaagaacag cctgattcca gcaggcctgg cttgggagga gatgctgctt ccactctacc
     1021 agaagtataa aagtgccatc acatggggag accaggattt attaaatatt attttttatt
     1081 acaacccaga gtgtctctat gtgttcccct gccagtggaa ctaccgccct gaccattgca
     1141 tgtatggaag caactgcaaa gaggctgaac gggaaggcgt gtctgttctg catggcaacc
     1201 ggggtgtcta ccacgacgac aaacaaccca ctttccgagc gctttatgaa gccatccggg
     1261 attttccctt tcaggacaat ctgtttcaat ctatgtacta ccctctgcag ctgaagtttt
     1321 tggagacggt gcacaccctg tgtggacgga tcccccaggt ttttctcaag caaattgaga
     1381 agacgatgcg aagggcttac gagaagcacg tcatcatcca catgggcccc aaccccatga
     1441 gctgagccag tgtctgggac cgaggacgtg gatccttacg ctgcctggat atttgtgtgt
     1501 gtgtgtgtga atatttaatg gtgctctgtg actgttgcgg ttcaaaagcc tgattgtatt
     1561 ttcctaagtt aattatccct aaaagggaat atgcttttct ttattttctc ctgatatctc
     1621 ctgaatcttt ttatttttaa agttatttta tgaatcttat attgtcccaa tgggctgaga
     1681 gagaaaaggg gaactttttc tagccctcaa atatgagccc ctgttgatat atgcagctat
     1741 cgtgataatc tggatttctt gagaatcttc ctatgcaact tgctctctca taccctatta
     1801 aaaagcaata catgttcagg ctgtaa
//
