LOCUS       NM_008192               8331 bp    mRNA    linear   ROD 01-JUN-2024
DEFINITION  Mus musculus guanylate cyclase 2e (Gucy2e), mRNA.
ACCESSION   NM_008192
VERSION     NM_008192.3
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 8331)
  AUTHORS   Ng,L., Liu,H., Liu,Y. and Forrest,D.
  TITLE     Biphasic expression of thyroid hormone receptor TRbeta1 in
            mammalian retina and anterior ocular tissues
  JOURNAL   Front Endocrinol (Lausanne) 14, 1174600 (2023)
   PUBMED   37033230
  REMARK    Publication Status: Online-Only
REFERENCE   2  (bases 1 to 8331)
  AUTHORS   Naggert,A.S.E.N., Collin,G.B., Wang,J., Krebs,M.P. and Chang,B.
  TITLE     A mouse model of cone photoreceptor function loss (cpfl9) with
            degeneration due to a mutation in Gucy2e
  JOURNAL   Front Mol Neurosci 15, 1080136 (2023)
   PUBMED   36698779
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 8331)
  AUTHORS   Broekmans,K., Giesen,J., Menges,L., Koesling,D. and Russwurm,M.
  TITLE     Angiotensin II-Induced Cardiovascular Fibrosis Is Attenuated by
            NO-Sensitive Guanylyl Cyclase1
  JOURNAL   Cells 9 (11), 2436 (2020)
   PUBMED   33171621
  REMARK    GeneRIF: Angiotensin II-Induced Cardiovascular Fibrosis Is
            Attenuated by NO-Sensitive Guanylyl Cyclase1.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 8331)
  AUTHORS   Yang,F., Ma,H., Butler,M.R. and Ding,X.Q.
  TITLE     Potential contribution of ryanodine receptor 2 upregulation to
            cGMP/PKG signaling-induced cone degeneration in cyclic
            nucleotide-gated channel deficiency
  JOURNAL   FASEB J 34 (5), 6335-6350 (2020)
   PUBMED   32173907
REFERENCE   5  (bases 1 to 8331)
  AUTHORS   Collin,G.B., Gogna,N., Chang,B., Damkham,N., Pinkney,J., Hyde,L.F.,
            Stone,L., Naggert,J.K., Nishina,P.M. and Krebs,M.P.
  TITLE     Mouse Models of Inherited Retinal Degeneration with Photoreceptor
            Cell Loss
  JOURNAL   Cells 9 (4), 931 (2020)
   PUBMED   32290105
  REMARK    Review article
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 8331)
  AUTHORS   Coleman,J.E. and Semple-Rowland,S.L.
  TITLE     GC1 deletion prevents light-dependent arrestin translocation in
            mouse cone photoreceptor cells
  JOURNAL   Invest Ophthalmol Vis Sci 46 (1), 12-16 (2005)
   PUBMED   15623748
  REMARK    Erratum:[Invest Ophthalmol Vis Sci. 2005 Feb;46(2):414]
REFERENCE   7  (bases 1 to 8331)
  AUTHORS   Coleman,J.E., Zhang,Y., Brown,G.A. and Semple-Rowland,S.L.
  TITLE     Cone cell survival and downregulation of GCAP1 protein in the
            retinas of GC1 knockout mice
  JOURNAL   Invest Ophthalmol Vis Sci 45 (10), 3397-3403 (2004)
   PUBMED   15452041
REFERENCE   8  (bases 1 to 8331)
  AUTHORS   Yang,R.B., Robinson,S.W., Xiong,W.H., Yau,K.W., Birch,D.G. and
            Garbers,D.L.
  TITLE     Disruption of a retinal guanylyl cyclase gene leads to
            cone-specific dystrophy and paradoxical rod behavior
  JOURNAL   J Neurosci 19 (14), 5889-5897 (1999)
   PUBMED   10407028
REFERENCE   9  (bases 1 to 8331)
  AUTHORS   Duda,T., Venkataraman,V., Goraczniak,R., Lange,C., Koch,K.W. and
            Sharma,R.K.
  TITLE     Functional consequences of a rod outer segment membrane guanylate
            cyclase (ROS-GC1) gene mutation linked with Leber's congenital
            amaurosis
  JOURNAL   Biochemistry 38 (2), 509-515 (1999)
   PUBMED   9888789
REFERENCE   10 (bases 1 to 8331)
  AUTHORS   Yang,R.B., Fulle,H.J. and Garbers,D.L.
  TITLE     Chromosomal localization and genomic organization of genes encoding
            guanylyl cyclase receptors expressed in olfactory sensory neurons
            and retina
  JOURNAL   Genomics 31 (3), 367-372 (1996)
   PUBMED   8838319
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BB591650.2, BC057954.1 and AL645527.20.
            
            On Sep 17, 2009 this sequence version replaced NM_008192.2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            RNAseq introns :: single sample supports all introns SAMN00849374,
                              SAMN01164138 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-15                BB591650.2         2-16
            16-2358             BC057954.1         1-2343
            2359-2507           AL645527.20        142736-142884       c
            2508-2671           AL645527.20        141533-141696       c
            2672-2864           AL645527.20        141254-141446       c
            2865-3039           AL645527.20        140690-140864       c
            3040-3138           AL645527.20        140332-140430       c
            3139-3233           AL645527.20        140118-140212       c
            3234-3319           AL645527.20        139889-139974       c
            3320-8331           AL645527.20        134680-139691       c
FEATURES             Location/Qualifiers
     source          1..8331
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /db_xref="taxon:10090"
                     /chromosome="11"
                     /map="11 42.51 cM"
     gene            1..8331
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /note="guanylate cyclase 2e"
                     /db_xref="GeneID:14919"
                     /db_xref="MGI:MGI:105123"
     exon            1..77
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            78..816
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            817..1121
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1473
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1474..1558
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1559..1661
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1662..1763
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1764..1844
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            1845..2051
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2052..2208
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2209..2358
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2359..2507
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2508..2671
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2672..2864
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            2865..3039
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3040..3138
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3139..3233
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3234..3319
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     exon            3320..8331
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      8309..8314
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /note="hexamer: AATAAA"
     polyA_site      8331
                     /gene="Gucy2e"
                     /gene_synonym="GC-E; GC1; ROS-GC1"
                     /note="major polyA site"
ORIGIN      
        1 gggctgggct gccaggggag accgaagggg catcgatcct gtgacccctt agccaagccc
       61 tagccccgga ctttccgaag aaggcaatga gcgcttggct cctgccagcc ggagggcttc
      121 ccggcgccgg gttctgtgtc cctgcgcggc agtctccgtc cagtttctcg cgggtcctgc
      181 gctggccaag gcctgggcta ccgggactcc tgctactgct actgctccca tctccttctg
      241 ccctctctgc tgtgttcaaa gtgggggtgc tgggcccctg ggcttgcgac cccatctttg
      301 cacgggcccg accagacctg gctgcgcgtc tggccgccaa ccgcctgaat cgtgactttg
      361 ctttagacgg cggcccccgg ttcgaggttg cgctgctccc agagccctgc ctgactccgg
      421 gctcactagg ggctgtgtcc tctgcgctgt ctcgagtctc tggcctggtg ggtccggtga
      481 accccgcagc ctgtcggcca gccgaactgt tggctcaaga agctggagta gcgctggtgc
      541 cctggggctg ccctggcacg cgggcggcgg gtactacagc cccggcggtg acccccgctg
      601 cagatgctct ctacgtcctc cttagagcat tccgctgggc gcgcgtggcc ctgatcactg
      661 caccccaaga cctgtgggtg gaggcgggac gcgctctgtc cacagcactc agggcccggg
      721 gtttgccagt tgccctagtg acttccatgg agacttcaga ccggtctgga gcccgggagg
      781 ccctcgggag gatccgagat gggcctagag ttagagtagt gatcatggtg atgcactcgg
      841 tgctgctggg cggcgaggag cagcgctacc tactggaagc tgcagaagaa ctggctctga
      901 ctgatggctc cctggttttc ctgcccttcg acacgcttca ctacgctttg tctccaggcc
      961 cggaggctct ggctgcattt gtcaacagct cccagctccg cagggctcac gatgcggtgc
     1021 tcacactcac gcgccgctgt cctcctggag gcagcgtgca agacagcctg cgcagggctc
     1081 aagaacacca ggaactgccc cttgacctca acctgaagca ggtctctccg ctgtttggca
     1141 ccatctatga tgctgtcttc ctgttggctg ggggcgtgaa gagagcaaga acagcggtgg
     1201 gtggtggctg ggtgtcaggt gcatctgtag cccgccaagt acgggaagca caagtctctg
     1261 gcttttgtgg ggtcctggga agaaccgagg agccctcctt tgtgctgctg gacacagatg
     1321 catccggaga acagttgttc gcaacacacc tgctagatcc tgtcttaggc tccctgcgtt
     1381 ctgcagggac ccccatgcac ttccctagag gtggacctgc cccgggacca gacccttcct
     1441 gctggttcga tccagatgtg atctgcaacg gaggggtgga gccaggcctg gtctttgttg
     1501 gcttcctcct ggtgataggg atgggactga ctggagcctt cttggctcat tacttgaggc
     1561 acaggctgct acacatgcag atggcttccg gccccaacaa gatcatcttg acgttggaag
     1621 atgttacttt cctccaccca ccgggaggca gctctcgaaa ggtggtccag ggaagtagat
     1681 ccagtctggc tacccggagc gcatcagaca ttcgcagtgt ccccagccag ccccaagaga
     1741 gcaccaacgt tggcctctat gagggggact gggtttggct gaagaagttc ccaggggaac
     1801 atcatatggc tatcaggcca gcaacaaaga cagccttctc caagcttcga gagctccggc
     1861 atgagaatgt ggctctctac ttgggactct tcctggcggg tacagcagac agccctgcca
     1921 cccctgggga gggcatcttg gctgtggtct cagagcactg tgctcggggt tccctccatg
     1981 acctcctggc ccagagagaa ataaagctgg actggatgtt caagtcttcc ctcctgctgg
     2041 acctcatcaa gggaatgaga tatctgcacc atcgcggtgt ggcccacggg aggctcaagt
     2101 cacggaattg cgtggtggac gggaggttcg tgctcaaggt gacagatcat ggccatgggc
     2161 gactgctgga agcgcaaagg gtgttaccgg aacctcccag tgcagaggat cagctatgga
     2221 cagccccaga gcttcttcgg gacccctccc tggagcgccg gggaactcta gctggtgatg
     2281 tctttagtct ggccatcatc atgcaggagg tcgtgtgccg cagcacccct tatgccatgc
     2341 tggaactaac gcccgaggaa gtaatacaga gggtgcggag ccctcctcca ctgtgtcggc
     2401 ccttggtgtc catggaccag gcacccatgg agtgcatcca gctgatgaca caatgctggg
     2461 cagagcatcc agaacttcgg ccttccatgg acctcacctt tgacctgttc aagagcatca
     2521 acaagggccg gaagaccaac atcatcgact ccatgcttcg gatgctggag cagtactcta
     2581 gtaacctgga ggatctgatc cgagaacgca cagaggagtt agagcaggag aagcagaaga
     2641 cagacaggct gctcacacag atgctgcctc catctgtggc tgaggccctg aagatgggga
     2701 catctgtgga gcctgagtac tttgaagagg tgacactcta cttcagtgac atcgtgggct
     2761 ttaccaccat ttcagccatg agcgagccta ttgaggtggt agacctgctt aatgacctct
     2821 atactctctt cgatgccatc atcggtgccc atgatgtcta taaggtggaa acaattggag
     2881 atgcatatat ggtggcctcc gggctgccgc agaggaacgg gcagcggcac gctgcagaga
     2941 ttgccaacat gtcactggac atcctcagtg cagtcggctc cttccgcatg cgccatatgc
     3001 ccgaggtacc ggtgcgcatc cgcattggtt tgcactcagg cccgtgcgtg gcgggtgtgg
     3061 tgggcctcac catgcctcgg tactgcctgt tcggggacac ggtcaacact gcctcgagaa
     3121 tggagtccac tggactgcct taccgcatcc acgttaacat gagcactgtt cggattcttc
     3181 gcgctctgga ccaaggcttc cagatggagt gtcgaggccg cacggagctg aagggcaagg
     3241 gtattgagga cacgtactgg cttgtgggca gacttggctt caacaagccc attcccaaac
     3301 cacctgatct gcagccaggg gccagcaacc atggtatcag cctgcaggag attcccccag
     3361 agagacgcaa gaagctggag aaagccaggc caggccagtt tactgggaag tgaagctcta
     3421 ctggggacag gtatcgtgtc ttccctcacc ctcagaagta gagtaaaaag attattgttt
     3481 tgtgtatata ttaattaatg ctacaaatta ataaagcggc aattattcct taaccacctt
     3541 tccccccccc aataacgaca cagagacctt ttaatatttc aaagctttag gccttatctg
     3601 ggcagactct caactagctc acctaagtta actgaaccac ctagctatat ccagccacat
     3661 ggatagctat acattctagg cgtgtgacca agccagtctc ctccatgcct cctggtgaca
     3721 tgacagggtt tttctttttc ccaaagttcc tttcttcctt ccaggctgtc ccgcttgcac
     3781 ttcctgccca gctcataggc tgtcagattt ttttttatta aagccaatca aaggatgctt
     3841 tgggttggtg agaaaggaca gagacagttt cacacagtgt accccaacag tcaggaaccg
     3901 ctcccttctg tgggtataga gggtggatgt atgtcctagg ggtcaggctc ctcctcacca
     3961 gattagagac tgggtagggg ttgcctgaat gctgtcacac ccaagcccgt gtccccattc
     4021 ctctctgatt tagggggcag aggctgactc ctcagcccat aaaagagact tcccttggag
     4081 gaagtatcag cttcaggtat actcattcag caggtctggg gtcatcccag caccaggttt
     4141 gccctgactc ccccgaacat aagccaggca tctcagagag gcccctcagg tatgtactcc
     4201 gcagaggaga gaactcttga ggatagcatt taccagaggc cagtgtgagg ttgcttctgc
     4261 agttctgtca gagcaggtgg ccttcatgtc ttcctctgag acagctttta ttccttcagg
     4321 agtattctgc aaggcccttc ctgaagttcc tgctacacat gggactaagg cccaaggctt
     4381 ctgtccagtt ctgcctccaa ggattctgag ccaggaatct gctgcaaacc agctctgtga
     4441 ccctgggaag atctgaagtg ctgcccaggc cctcctcagt ggtagaatgg agggggggaa
     4501 ctaagcggtt tccatcacct gtggccctta cagtgtggct ttagaatgac tgatcccatt
     4561 gggcacatgc ccccccccac ccccgccctg ttccaaggac cctgagctca ttggagagtg
     4621 cagaggtggc agtcccccac tctctaggtc ctgtgagacc ccaaaagtaa ggatctgggt
     4681 tcagaaaccc caggggaagt ggaggcctca tgttctacca ggtcaggggt catgatgtag
     4741 cctggaaaga ccaggacctc cgttcacccc aagtcctatt ctcaactcca tcactcactg
     4801 ttcagaaact ggttccttct ccaatgggca gaaccaaagc acttgcccaa gtgcagagaa
     4861 aagcttgctc tgggggaggg aaactagctg cacccaaact ttgctaacca gagtggtaat
     4921 gaatagttca ctctcagctt agctgggtgc tggtgaattg accatcaaag aaaaccattt
     4981 ctgctgagat ctttgtaaca agcgcccatg ctcaggactg gcaaatcccc agctgcagtt
     5041 tcctttgcag aacttggagg tgccagagcc tggactttgg catgtttgac tctggctgtc
     5101 ttctgtcatt gacagaattc tgtcacccag actctggctg gagactgtta gcaccagaca
     5161 cccagtaggt ggcgagtgtc aggacctggt gatgtgcaca actggagagg cgttgacagt
     5221 atctgaagga gactcactgg agccctcatt atgggaggca cagctggcag gccagccgca
     5281 ttggcatcac tgttagaact caggatcact ccacagccac aggtcaagtc tgcatgttaa
     5341 ggggacccct caaagcatta caggaccaca acaacttctt aatctgagga tgcccaggac
     5401 agaaattagt cattatactt gtttgtttgg gctcatgaga tgtttttatt tggggctaaa
     5461 acaattagaa aatcaattta aagtgacata cacacacaca catatttgaa aatcaactta
     5521 aggtagtaca ctaaacagag aggggggtgg ggaatatgtg caccattgga gtcagagtca
     5581 ggtatagtag cacacacatg gctttaatgc cagcactgag caggtagaga cagatggatc
     5641 tgggtttgaa gccagactgg tatacatagt gagttccagg ccagccaggg ctgccattag
     5701 aacctatcta aacaaaacaa ctgtatataa ttatataggt actctatatg ctagggctag
     5761 agagaaagct cagtggtgaa gagcacttgt tagttttcca aaggatccag gtttgatatc
     5821 caagacctac agagagccta acagtggtct attaactcca gttctgggga cctgacactc
     5881 ttctggcctc tgtgggcacc aggcatgcac atgatacaca gatacactca ggcaaaacac
     5941 ctatacacat aaaatgaata attttaagat aaatctaaaa atcttgactt tatttaaaaa
     6001 ataaaaacat atatagtcac ctctaagtat ctataaggaa ccaattcaag ggccttgatg
     6061 gatgctaaat cccttggatc tcaagtcccc tatataagat gggaattttt aaattgtacc
     6121 tatgcccttt atcctgtgtg ctttaagtaa tttctggatt ctttataatg tatatggtag
     6181 ggaataatga caagaaaaac cgtcagtaca tggtcactgc agacacagcc tctaggccta
     6241 actgcacaat gcacagtcat ggttggcttt gttgacataa aaaccacagc tctcgtctta
     6301 aaggagataa gagatggttt gttctggaat cattttgagt gaccatggcc tggggacaca
     6361 gatttcggtt atcccagatt ccatgttcca acgtggaagc agttacatgg ggttttacat
     6421 aaggaagaac atcataagtc aaggcaagtt ttaaatacat gggtattaac aagttttaaa
     6481 tacatgggat ataacagagg tgcacacagc cagatggggg aagcctgtct ataggccaga
     6541 ggtgctgttt atgaaagctc ttggattggt ggaagcctgt gttctgctaa attaacagct
     6601 tctaggagct gcttcttatt acaagatgtc agctctacat taatagcttc tgagagactt
     6661 ctattatcac caggtgttag ttcctataca gaatggggta aggagtggct gttctggaag
     6721 gtaaagctag cccaggacag cccaagttaa agtaattaat ctcaaaacct acaaaattcc
     6781 tgcccagatt ccaatagatc catcagtctc tgcagacgca gcttcttttc aggaaatttc
     6841 agaaaaaata caaagggcta actgtgctac agtctccctt ttcctgaaat caaagccacc
     6901 atgtggggct tgtatcactc cctggccaca gtcactttaa tccaggacgg cattctccag
     6961 ttctcaccgg tccttactag tccccaataa tgctagcacc cctgcctggc acccgtagac
     7021 attctgcccc gggtgttaag atcttagctg cttctagaga tttctggttt tctcctcctc
     7081 ttcttcctcc ctgtccccct cctcttcttc ctttcttttt gtactgatga atggcttcct
     7141 aatggcaata ataataatca taaattaaat acatgcagcc ctttcagttc tggttagcta
     7201 agtggtgctg ctaataggct atttagtgca atttaaaaat cttttagcta tgttcataga
     7261 tgatgagtta aagctgaaaa caaagcaaaa aaagatctga tgtgcatttc acattgttaa
     7321 acatctttca tacaagtttt tctctgtact tgggtcccag ggttgaaagg tagattccaa
     7381 attgctggcc ttagacctga ctggggatta gctctcaaaa cttctgtcct tccttccctc
     7441 ctgttctctc ccatcccttc ctcccctttc tgtctggggc ttggagtagc tgttagtatt
     7501 taattcagga agtctcaaga aagaatcacc ctgagttagg agctggagga ctagcctggg
     7561 caggctgggg cagggctcga ggagagggga gaagagaaga aaggtttcat tgctcctcac
     7621 aaggccactc tatccctcac tctaccccat tactccctct gtctccttct ctggccccac
     7681 tctcttccct tttctctcct agaccccctt tgaccacgtt tctcccagac tttctctgca
     7741 gcttccccta tttctgagga caccccaccc ccacccctgt caacctggga ctctgattac
     7801 taactgccaa tcttagagtc ctgactcaaa tattccctgc ctcccactct cttgtccaca
     7861 gatccaggca actcacggcc catgaaagca cccgccgtgg tcatcacctg gtactccacg
     7921 gtttcagagg tgtttttgct acctcagcca gcaggcctgc cccaggagcc cacacttggg
     7981 ctgttcttgc ctttgggatg gctctgtagc tgggacccat catagccaaa gcagggactt
     8041 tcctcagcta ctgtccgggt tccaaagggt gccccagggc tcactggcgc cttcctgtgt
     8101 gatgctgttt cagcctggtc cctgctctac ctgcttatgt ggggtggacc ccaggcactc
     8161 ccctttgggg aagtggggtt acacccaggc tgggacttgt gacataacgt cgtagggtca
     8221 tccgtactca taggaatctt ttggactttg catccagcac accaagtggt gtatcttggt
     8281 ggttgggacc tgggatggta gtggctggaa taaaggtatg tgttcttctg c
//
