LOCUS       NM_145147               1615 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus GTP binding protein 6 (putative) (Gtpbp6), transcript
            variant 1, mRNA.
ACCESSION   NM_145147
VERSION     NM_145147.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1615)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 1615)
  AUTHORS   Gianfrancesco,F., Sanges,R., Esposito,T., Tempesta,S., Rao,E.,
            Rappold,G., Archidiacono,N., Graves,J.A., Forabosco,A. and
            D'Urso,M.
  TITLE     Differential divergence of three human pseudoautosomal genes and
            their mouse homologs: implications for sex chromosome evolution
  JOURNAL   Genome Res 11 (12), 2095-2100 (2001)
   PUBMED   11731500
REFERENCE   3  (bases 1 to 1615)
  AUTHORS   Gianfrancesco,F., Esposito,T., Montanini,L., Ciccodicola,A.,
            Mumm,S., Mazzarella,R., Rao,E., Giglio,S., Rappold,G. and
            Forabosco,A.
  TITLE     A novel pseudoautosomal gene encoding a putative GTP-binding
            protein resides in the vicinity of the Xp/Yp telomere
  JOURNAL   Hum Mol Genet 7 (3), 407-414 (1998)
   PUBMED   9466997
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK152225.1 and AK082192.1.
            
            On Jan 19, 2008 this sequence version replaced NM_145147.4.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK152972.1, AK152225.1 [ECO:0000332]
            RNAseq introns              :: mixed sample support SAMN00849374,
                                           SAMN00849375 [ECO:0006172]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-1074              AK152225.1         2-1075
            1075-1613           AK082192.1         951-1489
            1614-1615           AK152225.1         1615-1616
FEATURES             Location/Qualifiers
     source          1..1615
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 53.3 cM"
     gene            1..1615
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /note="GTP binding protein 6 (putative)"
                     /db_xref="GeneID:107999"
                     /db_xref="MGI:MGI:1306825"
     exon            1..342
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /inference="alignment:Splign:2.1.0"
     CDS             27..1571
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /note="pseudoautosomal GTP binding protein-like, like"
                     /codon_start=1
                     /product="putative GTP-binding protein 6"
                     /protein_id="NP_660129.2"
                     /db_xref="CCDS:CCDS51604.1"
                     /db_xref="GeneID:107999"
                     /db_xref="MGI:MGI:1306825"
                     /translation="MLFLRAAVLPGFWLPRVRRVQLVRSPAVTLPSPVRTVHAGSRVW
                     GSAWAGGGPVRGGGEEDPREDEEEEEDELLRAPPLLPLDTQRVCVLHPDVKRPAGKKP
                     RSTAEWQVAEAAALVRALPGWSVASTLVVPSAAPGSRLVFGKGNFQDVTEKIKGCQDI
                     TSVFLNVERMAPPTKKELESAWGLRVFDRFTLVLHIFRCNARTREARMQLALAEIPLL
                     RSSVNTDSGQQDQQGWGSRYIMGSGESPTELRARALRDRELRLRRVLERLRDKRRLMR
                     KERVRREFPVVSVVGYTNCGKTTLIQALTGEAALQPRDQPFATLDVTVHAGLLPSRLR
                     ILYVDTIGFLSQLPHSLIHAFSATLEDVAYSDVLVHVTDVSHPDAELQKATVLSTLRG
                     LHLPPALLESALEVHSKVDLVPGYTPPCSGALAVSAISGRGLDELKAALEASVLRATG
                     RQVLTLCVRLGGPQLGWLYKEAVVQQVQELPEGDAAHVTVVITQAAYGRFRKLFPIDA
                     PSALPH"
     exon            343..480
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /inference="alignment:Splign:2.1.0"
     exon            481..551
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /inference="alignment:Splign:2.1.0"
     exon            552..682
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /inference="alignment:Splign:2.1.0"
     exon            683..753
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /inference="alignment:Splign:2.1.0"
     exon            754..912
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /inference="alignment:Splign:2.1.0"
     exon            913..1121
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /inference="alignment:Splign:2.1.0"
     exon            1122..1270
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /inference="alignment:Splign:2.1.0"
     exon            1271..1423
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /inference="alignment:Splign:2.1.0"
     exon            1424..1615
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1585..1590
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /note="putative"
     polyA_site      1613
                     /gene="Gtpbp6"
                     /gene_synonym="Pgbpll; pgpl"
                     /note="putative"
ORIGIN      
        1 agtctctcgc tgcgcgcgca cgcgccatgc tttttctgcg cgccgccgtg ctcccggggt
       61 tctggctccc gcgtgtgcgc cgcgtacaac tcgttcggag ccccgcggtg accctgccaa
      121 gtcccgtccg cactgtccac gccgggagcc gggtctgggg gagcgcgtgg gcggggggcg
      181 gtcccgtccg tggtgggggc gaggaggacc cccgtgagga cgaagaggaa gaggaggatg
      241 agctgctccg cgccccaccc ctcctgccct tggatacaca gcgcgtttgc gtcctgcatc
      301 ctgacgtcaa acgcccggcc ggaaaaaagc ctcgaagcac agcggagtgg caggtggcag
      361 aggcggccgc cctggtgcgc gcacttccag gatggtcggt cgcgagtacc ctggtggtgc
      421 ccagcgcagc gcctggcagc aggctggtgt tcggcaaggg caactttcag gacgtgacag
      481 aaaagatcaa gggatgccag gacatcacgt ccgtgttcct gaacgtggag aggatggcgc
      541 caccgaccaa gaaggagctg gagtccgctt ggggtttgcg tgtgttcgac agattcaccc
      601 tagttctgca tatcttccgt tgtaacgcac gcacgaggga ggcccggatg cagctggcgc
      661 tggcagagat cccgctcctc aggtcctctg tgaataccga ctctgggcag caagaccagc
      721 aaggctgggg ctcccggtac atcatggggt caggagagtc acccacggag ctgcgggccc
      781 gcgcactcag ggaccgggag ctgcggctcc gtcgtgtcct tgagcggctt cgggataagc
      841 ggaggctgat gcggaaggag cgggtgcggc gagagttccc tgtggtgtca gtggtgggat
      901 acaccaactg tgggaagacc acactcatcc aggctctgac gggtgaggct gctttgcagc
      961 cgcgggacca accgtttgct actcttgatg tcaccgtaca cgcggggttg ctcccctcac
     1021 gcctgcgcat cttgtacgtg gacactattg gcttcctgtc ccagctgccg cacagcctga
     1081 tccatgcgtt ctctgccaca ctggaggacg tggcttactc ggatgtcctg gtgcacgtga
     1141 ctgatgtgag ccaccctgat gcagagctgc agaaggccac tgtcctgtcc acattgcggg
     1201 gcctgcatct gcctcccgca ctgttggagt cagcgttgga ggttcacagc aaggtggacc
     1261 tggtgccggg gtacactcca ccatgctctg gagccctggc cgtgtctgca atctcagggc
     1321 gtgggctaga cgagctgaag gccgcactgg aggcgtcagt gctgcgtgcc acaggcaggc
     1381 aggtcctcac gctatgtgtg cgccttgggg gaccccaact tggctggctc tataaggagg
     1441 cggtggtgca gcaggtgcag gagctgccag agggtgatgc ggcccacgtg accgtcgtca
     1501 tcacccaggc tgcctatggc cggttcagga aactgttccc cattgacgcc ccttctgccc
     1561 tcccacattg actgacagta acttattaaa gcaggatatg tcctgtgtct ccctc
//
