LOCUS       NM_153116               2975 bp    mRNA    linear   ROD 02-MAY-2024
DEFINITION  Mus musculus GTP-binding protein 10 (putative) (Gtpbp10),
            transcript variant 1, mRNA.
ACCESSION   NM_153116 XM_131888 XM_912485
VERSION     NM_153116.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2975)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 2975)
  AUTHORS   Koscielny,G., Yaikhom,G., Iyer,V., Meehan,T.F., Morgan,H.,
            Atienza-Herrero,J., Blake,A., Chen,C.K., Easty,R., Di Fenza,A.,
            Fiegel,T., Grifiths,M., Horne,A., Karp,N.A., Kurbatova,N.,
            Mason,J.C., Matthews,P., Oakley,D.J., Qazi,A., Regnart,J.,
            Retha,A., Santos,L.A., Sneddon,D.J., Warren,J., Westerberg,H.,
            Wilson,R.J., Melvin,D.G., Smedley,D., Brown,S.D., Flicek,P.,
            Skarnes,W.C., Mallon,A.M. and Parkinson,H.
  TITLE     The International Mouse Phenotyping Consortium Web Portal, a
            unified point of access for knockout mice and related phenotyping
            data
  JOURNAL   Nucleic Acids Res 42 (Database issue), D802-D809 (2014)
   PUBMED   24194600
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC026813.4, AK160252.1 and AC068663.5.
            
            On Oct 17, 2017 this sequence version replaced NM_153116.1.
            
            Transcript Variant: This variant (1) encodes the longest isoform
            (1).
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC034507.2, AK139595.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3                 AC026813.4         83407-83409
            4-622               AK160252.1         2-620
            623-1720            AK160252.1         622-1719
            1721-2975           AC068663.5         9697-10951
FEATURES             Location/Qualifiers
     source          1..2975
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 3.02 cM"
     gene            1..2975
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /note="GTP-binding protein 10 (putative)"
                     /db_xref="GeneID:207704"
                     /db_xref="MGI:MGI:2385599"
     exon            1..109
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             77..1177
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /note="isoform 1. is encoded by transcript variant 1"
                     /codon_start=1
                     /product="GTP-binding protein 10 isoform 1."
                     /protein_id="NP_694756.1"
                     /db_xref="CCDS:CCDS39006.1"
                     /db_xref="GeneID:207704"
                     /db_xref="MGI:MGI:2385599"
                     /translation="MVRCGCALLRKYGNFIDNLRIFTKGGSGGMGYPRLGGEGGRGGD
                     VWVVAHKNMTLKQLKNKYPQKRFVAGGGANSRVSALQGSKGKDCEVPAPVGISVTDEN
                     GQVLGELNKEEDRVLVAKGGLGGKLHTNFLPLKGQKRIVHLDLKVIADVGLVGFPNAG
                     KSSLLSRVSHATPVIADYAFTTLRPELGKIMYNDFKQISVADLPGLIEGAHMNKGMGH
                     KFLKHLERTRQLLFVVDISGFQLSSVTPYRTAFETIILLTKELELYKEELQTKPALLA
                     INKMDLPDAQVKLQELMKQLLSPEDFLHLFETKMIPEKALEFQHIVPISTVTGEGIAE
                     LKSCIRKALDEQDGKESDAHRSKQLLNLQSSS"
     exon            110..303
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            304..395
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            396..540
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            541..614
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            615..667
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            668..775
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            776..853
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            854..977
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            978..2975
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /inference="alignment:Splign:2.1.0"
     regulatory      2952..2957
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /note="hexamer: GATAAA"
     polyA_site      2975
                     /gene="Gtpbp10"
                     /gene_synonym="4930545J22Rik"
                     /note="major polyA site"
ORIGIN      
        1 agtagtgacg tcagtacgcg cgcccgaccg aagtttgtcc ggattctgcg ggcgggagtc
       61 ctgccccttg gagctcatgg tgcgctgcgg ttgcgctttg ttgagaaagt atggaaattt
      121 cattgataac ctgagaatct tcaccaaggg aggaagcggt ggaatgggtt accctcgttt
      181 aggtggagaa ggtggaagag gtggtgacgt ctgggttgtg gcccataaaa atatgacctt
      241 aaaacaactt aaaaacaaat atcctcagaa acggtttgtg gccggaggag gagcaaacag
      301 tcgagttagc gcactgcagg gctccaaggg aaaggactgt gaagtgcctg ctcctgtggg
      361 tatctcagta actgatgaaa acggccaagt gctaggagaa ctcaataaag aagaagacag
      421 agttctggtt gctaaaggtg gccttggtgg caaattacat acaaatttct tacctttgaa
      481 aggtcagaag cgcatagttc accttgacct aaaagtcata gctgatgtag gcctagtagg
      541 attcccaaat gctggaaaat cctccttact gagtcgggtt tcccatgcta cacctgtgat
      601 tgcagattat gcgtttacaa cactaaggcc tgaactcgga aagattatgt acaatgattt
      661 caaacagatt tcagtagctg atctcccagg tttgatagaa ggagcgcata tgaacaaagg
      721 catgggccac aagttcctca agcatttaga gagaaccaga caactgcttt ttgttgttga
      781 tatttctggg tttcagcttt cttctgtaac tccatatagg actgcctttg aaactataat
      841 acttctcaca aaagagttgg agttgtacaa agaagaacta cagacaaaac ccgcactctt
      901 agcaattaat aagatggact tgccggatgc ccaagttaaa cttcaggaac tgatgaagca
      961 gctcctgagc cctgaagatt ttctgcattt atttgaaaca aagatgattc cagagaaggc
     1021 tctagagttc cagcatatcg ttcccatctc aacagtcact ggggaaggca ttgcagagtt
     1081 gaagagctgt ataaggaaag cactggatga acaggatggc aaagaaagtg atgcgcatcg
     1141 gagcaaacag ttgctcaatt tgcagagttc cagttgagca tcttagactg agccacatca
     1201 aagtgtgcgg ctactgtctc cagaaaaggc agcattcaaa cctagtacag cgtattgacg
     1261 caatactctt tcttctaagg atcagaaaat catgtttaaa acgtggacga gcctgaaaag
     1321 catgatgttc aaagaagcca ggcacgacag caagacaaat atcaatgatc tcacatgcgg
     1381 aatcttagaa agacaaatct gaactgatag aaatcctgaa aaatgataat tttgtgtagt
     1441 ataaatagga gctagaagat taagagatgt tggtcaaaag atacaaagtt tcagttaagc
     1501 tttacagatc tgttatgtac cttgtttgta gaataatgta tcatatttaa aaatttgtaa
     1561 gaaagtagtt tttaagtgtt ctgaccacaa tttttgagaa aaatatatat tttaaaatag
     1621 atttgactct gttttaaaac atgctgtata tgatatagac acgtgtataa ttttatatca
     1681 gttaaaaata gtattgaaat tacattaatt tgaaagcttt tccacatttt aaggatagta
     1741 tttatcgata tatgtatcat cattcaggaa aatacatttt catcttcctt tccttcttct
     1801 ggctttagct cagcaagatg gttcactttt ttgcataacg tgtacagaag acccaggcta
     1861 gcaagcacac agtctagcaa ggctcttgta tttcattcct gatgtgggta ctaattaggt
     1921 cctatccctt tggtgggagc ttgacctcac agtctgacta atggataact gggtcaaaga
     1981 gtcctcactg gctaacctac tttgattttc aagtttctta aaattaaccc ctttattcca
     2041 ttatttttca aatttagtca gtttatgttg gccatttgaa gtctctagga agaataaatt
     2101 atataatcag cggggaagcc caccttccaa gaagaaacag aatttttttt cctttaggtg
     2161 aaatgtgaaa tgtacatgct tacttctaaa aaatacatcc aagcagcaca caggagcagg
     2221 aggcaacaga ccttagctag agaaagttac agtcagcggc ttaaggtttt atgaaaattt
     2281 tacatttttt ccacaaatga gttcactgta attttctttc tttctttttt tttttctttt
     2341 tgcaaagtag cagcaagtta atgagcttta aaaaattgct tactaagcgc ggtagtgtgg
     2401 gcctctggtg gtgtggtaag ctctggtaag cgtggtggtg tgggcctctc ccacacccct
     2461 tgggaaggag aagctaggag ttttgagtaa aacacagccc ctcctgggtg acatagcggg
     2521 ttgtaggttg ctctggattt cataatggaa ccaggtttaa aaatactggt ttttaacagt
     2581 atgtgttttg attattgtat gtggtttgtt gttttgtcct caagtaagtc tgtgtgactg
     2641 tgtgaatgaa gtgtccatga cagccagaag agggggtcag atatcctgga actgaaattc
     2701 tctacagtgg aaagccacca agcaagtgtc ggaaatcaga accaggtcct ctgcaagagc
     2761 agccagggtt cttaacttcc aagccttctt ctccagcccc tttctttaat acttttttaa
     2821 tttgttaaaa attatttaat aatttattgt ttagtaaaag ttatggttat tgaccccttt
     2881 ttaaaaatcc tttttttaat tatatgttga ttgtacttaa atttcttctg acttaataat
     2941 gtgtatagtt tgataaaata ttatttgaat tttaa
//
