LOCUS       NM_013818               3444 bp    mRNA    linear   ROD 10-FEB-2025
DEFINITION  Mus musculus GTP binding protein 1 (Gtpbp1), mRNA.
ACCESSION   NM_013818
VERSION     NM_013818.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 3444)
  AUTHORS   Terrey,M., Adamson,S.I., Gibson,A.L., Deng,T., Ishimura,R.,
            Chuang,J.H. and Ackerman,S.L.
  TITLE     GTPBP1 resolves paused ribosomes to maintain neuronal homeostasis
  JOURNAL   Elife 9, e62731 (2020)
   PUBMED   33186095
  REMARK    Erratum:[Elife. 2021 Jun 04;10:e70785. doi: 10.7554/eLife.70785..
            PMID: 34085931]
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 3444)
  AUTHORS   Liu,D.C., Soriano,S., Yook,Y., Lizarazo,S., Eagleman,D.E. and
            Tsai,N.P.
  TITLE     Chronic Activation of Gp1 mGluRs Leads to Distinct Refinement of
            Neural Network Activity through Non-Canonical p53 and Akt Signaling
  JOURNAL   eNeuro 7 (2) (2020)
   PUBMED   32161037
  REMARK    GeneRIF: Chronic Activation of Gp1 mGluRs Leads to Distinct
            Refinement of Neural Network Activity through Non-Canonical p53 and
            Akt Signaling.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 3444)
  AUTHORS   Sansom,S.N., Griffiths,D.S., Faedo,A., Kleinjan,D.J., Ruan,Y.,
            Smith,J., van Heyningen,V., Rubenstein,J.L. and Livesey,F.J.
  TITLE     The level of the transcription factor Pax6 is essential for
            controlling the balance between neural stem cell self-renewal and
            neurogenesis
  JOURNAL   PLoS Genet 5 (6), e1000511 (2009)
   PUBMED   19521500
REFERENCE   4  (bases 1 to 3444)
  AUTHORS   Munton,R.P., Tweedie-Cullen,R., Livingstone-Zatchej,M.,
            Weinandy,F., Waidelich,M., Longo,D., Gehrig,P., Potthast,F.,
            Rutishauser,D., Gerrits,B., Panse,C., Schlapbach,R. and Mansuy,I.M.
  TITLE     Qualitative and quantitative analyses of protein phosphorylation in
            naive and stimulated mouse synaptosomal preparations
  JOURNAL   Mol Cell Proteomics 6 (2), 283-293 (2007)
   PUBMED   17114649
REFERENCE   5  (bases 1 to 3444)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   6  (bases 1 to 3444)
  AUTHORS   Watanabe,M., Yoshida,K., Hida,M., Kato,H., Uchida,K., Yamaguchi,R.,
            Tateyama,S. and Sugano,S.
  TITLE     Cloning, expression analysis, and chromosomal mapping of GTPBP2, a
            novel member of the G protein family
  JOURNAL   Gene 256 (1-2), 51-58 (2000)
   PUBMED   11054535
REFERENCE   7  (bases 1 to 3444)
  AUTHORS   Senju,S., Iyama,K., Kudo,H., Aizawa,S. and Nishimura,Y.
  TITLE     Immunocytochemical analyses and targeted gene disruption of GTPBP1
  JOURNAL   Mol Cell Biol 20 (17), 6195-6200 (2000)
   PUBMED   10938096
REFERENCE   8  (bases 1 to 3444)
  AUTHORS   Kudo,H., Senju,S., Mitsuya,H. and Nishimura,Y.
  TITLE     Mouse and human GTPBP2, newly identified members of the GP-1 family
            of GTPase
  JOURNAL   Biochem Biophys Res Commun 272 (2), 456-465 (2000)
   PUBMED   10833435
REFERENCE   9  (bases 1 to 3444)
  AUTHORS   Senju,S. and Nishimura,Y.
  TITLE     Identification of human and mouse GP-1, a putative member of a
            novel G-protein family
  JOURNAL   Biochem Biophys Res Commun 231 (2), 360-364 (1997)
   PUBMED   9070279
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BC046228.1.
            
            On Jul 13, 2005 this sequence version replaced NM_013818.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC046228.1, AK004612.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849374, SAMN00849375
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-3444              BC046228.1         1-3444
FEATURES             Location/Qualifiers
     source          1..3444
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="15"
                     /map="15 37.85 cM"
     gene            1..3444
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /note="GTP binding protein 1"
                     /db_xref="GeneID:14904"
                     /db_xref="MGI:MGI:109443"
     exon            1..203
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..2018
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /note="GP1; G-protein 1"
                     /codon_start=1
                     /product="GTP-binding protein 1"
                     /protein_id="NP_038846.2"
                     /db_xref="CCDS:CCDS27648.1"
                     /db_xref="GeneID:14904"
                     /db_xref="MGI:MGI:109443"
                     /translation="MAAERSRSPVDSPVPASMFAPEPSSPGAARAAAAAARLHGGFDS
                     DCSEDGEALNGEPELDLTSKLVLVSPTSEQYDSLLRQMWERMDEGCGETIYVIGQGSD
                     GTEYGLSEADMEASYATVKSMAEQIEADVILLRERQEAGGRVRDYLVRKRVGDNDFLE
                     VRVAVVGNVDAGKSTLLGVLTHGELDNGRGFARQKLFRHKHEIESGRTSSVGNDILGF
                     DSEGNVVNKPDSHGGSLEWTKICEKSSKVITFIDLAGHEKYLKTTVFGMTGHLPDFCM
                     LMVGSNAGIVGMTKEHLGLALALNVPVFVVVTKIDMCPANILQETLKLLQRLLKSPGC
                     RKIPVLVQSKDDVIVTASNFSSERMCPIFQISNVTGENLDLLKMFLNLLSPRTSYREE
                     EPAEFQIDDTYSVPGVGTVVSGTTLRGLIKLNDTLLLGPDPLGNFLSIAVKSIHRKRM
                     PVKEVRGGQTASFALKKIKRSSIRKGMVMVSPRLNPQASWEFEAEILVLHHPTTISPR
                     YQAMVHCGSIRQTATILSMDKDCLRTGDKATVHFRFIKTPEYLHIDQRLVFREGRTKA
                     VGTITKLLQTTNNSPMNSKPQQIKMQSTKKGPLSKREEGGPCGVPAAGGPPTGDEASS
                     LGTAQAASTSGLQPQPKPSSGGRRRGGQRHKVKSGACVTPASGC"
     exon            204..315
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /inference="alignment:Splign:2.1.0"
     exon            316..496
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /inference="alignment:Splign:2.1.0"
     exon            497..845
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /inference="alignment:Splign:2.1.0"
     exon            846..969
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /inference="alignment:Splign:2.1.0"
     exon            970..1084
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /inference="alignment:Splign:2.1.0"
     exon            1085..1229
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /inference="alignment:Splign:2.1.0"
     exon            1230..1412
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /inference="alignment:Splign:2.1.0"
     exon            1413..1548
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /inference="alignment:Splign:2.1.0"
     exon            1549..1727
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /inference="alignment:Splign:2.1.0"
     exon            1728..1928
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /inference="alignment:Splign:2.1.0"
     exon            1929..3398
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /inference="alignment:Splign:2.1.0"
     regulatory      3376..3381
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /note="hexamer: AATAAA"
     polyA_site      3398
                     /gene="Gtpbp1"
                     /gene_synonym="GP-1; Gtpbp"
                     /note="major polyA site"
ORIGIN      
        1 agttcttaaa gatggcggcg gagcggagtc gctccccggt cgactcgccg gtgccggcct
       61 cgatgttcgc ccccgagcct agctctccgg gggcggctcg ggccgccgcg gccgcggccc
      121 gactccatgg cggcttcgat tctgactgca gcgaggacgg cgaggcgctc aacggcgagc
      181 cggagctgga cctcaccagc aagctggttc tagtgagccc tacatcagag cagtatgaca
      241 gcctacttcg gcagatgtgg gagaggatgg acgagggatg cggagagacc atatatgtca
      301 ttgggcaggg atcagatggg actgagtacg ggctgagtga agctgacatg gaggcctcct
      361 acgccaccgt gaagagcatg gcggagcaga tagaggctga cgtcatcctc ttacgagaac
      421 gtcaagaagc gggcggccgt gtgcgtgatt acctagtcag gaaacgagtt ggagacaatg
      481 acttcctgga ggtcagggtg gcagtggtgg gcaacgtgga tgctggcaaa agcacactcc
      541 tgggagtcct aacacacggg gagctggaca atggccgtgg ctttgcccgc caaaaactct
      601 ttcgccacaa acatgagatt gaatctggtc gaaccagcag tgtgggcaat gacattctgg
      661 gctttgacag cgaaggcaat gtagtgaaca aacccgacag ccatggtggc agcctcgaat
      721 ggacaaagat ctgtgagaag tcctctaaag tgatcacctt catcgacttg gctggccacg
      781 agaagtacct taagaccact gtttttggca tgactggcca cttgcctgac ttctgcatgc
      841 tcatggtggg cagcaatgct ggcattgtgg ggatgaccaa ggagcatctg ggcttggcat
      901 tggcactcaa tgtacctgtg tttgtggttg tcaccaagat tgacatgtgt cctgccaaca
      961 tccttcaaga aaccctgaag ctgctacagc gcctgctgaa gtcaccaggc tgccggaaga
     1021 tccctgtcct ggtgcagagc aaagatgatg tgattgtcac agcctccaac ttcagctctg
     1081 agaggatgtg cccgatattc cagatctcca atgtcacagg tgagaacctt gacctgctca
     1141 agatgttcct caacctcctg tccccccgca ccagctaccg ggaggaggag cctgctgagt
     1201 tccagataga tgacacctac tctgtccctg gcgtggggac agtggtgtct gggaccaccc
     1261 tgcggggcct gatcaaactg aacgacacac tgctgctggg cccagacccc ttggggaact
     1321 tcctgtccat tgctgtcaag tcaatccatc gcaaacgtat gccagtcaag gaggtgcgcg
     1381 ggggccagac agcctccttt gcactgaaga agataaagcg ctcatccatc cggaaaggca
     1441 tggtgatggt ttccccacgc ctgaatcccc aggcctcctg ggagtttgag gctgagatcc
     1501 ttgtcctcca ccaccccacc acaattagtc cacgatacca agccatggta cactgtggga
     1561 gcatccggca aacagctaca attctgagca tggataaaga ctgtctgcgc acaggagaca
     1621 aggccactgt ccacttccgc ttcatcaaga ccccagagta tctgcacata gaccagcggt
     1681 tggtgttccg ggaaggtcga accaaggctg ttggcaccat caccaagctc ctccagacaa
     1741 ccaacaactc ccccatgaac tccaagcccc agcagattaa aatgcagtcc acaaaaaagg
     1801 gtcccctgag caaacgagag gaaggaggtc catgtggggt gccggcggca gggggacccc
     1861 cgactggaga tgaagcttcc tcactaggga ctgcacaggc tgcctcaacc agtgggctcc
     1921 agccacagcc caagcccagc agtgggggcc ggcgacgagg gggccagcgc cacaaggtga
     1981 agtcgggagc ctgtgtgact cctgccagcg gctgctgaat gtcccccagg tccacttgac
     2041 cacccatggg atcctcattg ctcactggcc actgctcacc aactgggcag agaatctttg
     2101 accaccaccg gcccactcca gtccacagcc agagagtcct cgttgccaca gcccgatttt
     2161 ccatgggggg ttgtatttat agggtgagga gggactagat gtccgaggac tgactgtcac
     2221 atgccacctt ccttactcac ggctttcgta catctgggcc cttaatttct atctttttat
     2281 tatatatttg tcccatgtgt atgtgtgtat ctgtgtgtct atgtgtgtct gtgtgagtgt
     2341 gtgcatgcac acgcctatag caggtgtgtg caggagtgca gctgaccctg tcagtctccg
     2401 tttcggtcct agctggacac cagcctccaa gagctgactg cctgcctgtc cttccatccg
     2461 tctgtatttg tctcagtgag atcctcagaa cctttaggga acctcagagc ctaaggcacc
     2521 tgtcttccct ggccaatggc ccctcttagc tagcagccct tctttggggc cgacctctgg
     2581 gcttagcagc ttctaccaga gcagggatcc cctagtctgt gatttgggga gtttaatggg
     2641 aagtggtggt ggcctctcct gtctcccctt tttcctccaa gctcttcagt ggcacctgtg
     2701 atgtgtggag gtagtgggga ctacattgta ggaccaccta ctctgactct tgacccttgc
     2761 catggatcca aagaactagg tgggctcatc tttagagaca atcctgggct tgcctggctg
     2821 gccctggctg ctctggcttc tgtgcccgca ggaggctctt cctgtttcta cttagatctc
     2881 tggctgagcc tcagagttcc gggctactag actgggtctt cctggttttg tagtacctcc
     2941 tttggtgggg gcggggaggt gctcctgagt tcagccagga ctagaaatgc tcctttccca
     3001 atgtcaccca acacaaccgc tacagccatg ccacatagca gtgaagggtc tgagccctga
     3061 tgccccattt ggggtataca agggcaggtg gcaatgcaga cccttctagg ccatcaaaag
     3121 ccctgctact gggttagggt gcggtgggct gcccagagca gtgtgggcac agccctgcac
     3181 catcgcctca ggctagggtg ctccttctca gccaggacag atcctcagct ggctggagcc
     3241 ctctacagcc ccacctcttc tcccaagctc tcttttgtcc tctgctcctg actgctcttc
     3301 cctctctccc tgtacttcca gctgtttcta gttaccactg ccccatggcc atggactgac
     3361 gagaccagca ttcacaataa aagtttgttt taagttgaaa aaaaaaaaaa aaaaaaaaaa
     3421 aaaaaaaaaa aaaaaaaaaa aaaa
//
