LOCUS       NM_026113               2578 bp    mRNA    linear   ROD 05-JUN-2024
DEFINITION  Mus musculus general transcription factor IIIC, polypeptide 6,
            alpha (Gtf3c6), transcript variant 2, mRNA.
ACCESSION   NM_026113
VERSION     NM_026113.5
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 2578)
  AUTHORS   Phillips,R.L., Ernst,R.E., Brunk,B., Ivanova,N., Mahan,M.A.,
            Deanehan,J.K., Moore,K.A., Overton,G.C. and Lemischka,I.R.
  TITLE     The genetic program of hematopoietic stem cells
  JOURNAL   Science 288 (5471), 1635-1640 (2000)
   PUBMED   10834841
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AC131684.4, BY110346.1, AK007816.1, AC164625.6 and AI430887.1.
            
            On Jan 13, 2018 this sequence version replaced NM_026113.4.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK162053.1, AK168070.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849375, SAMN00849380
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-16                AC131684.4         168063-168078       c
            17-49               BY110346.1         1-33
            50-826              AK007816.1         4-780
            827-989             AC131684.4         159647-159809       c
            990-2564            AC164625.6         170174-171748       c
            2565-2578           AI430887.1         1-14                c
FEATURES             Location/Qualifiers
     source          1..2578
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="10"
                     /map="10 21.79 cM"
     gene            1..2578
                     /gene="Gtf3c6"
                     /gene_synonym="2410016F19Rik"
                     /note="general transcription factor IIIC, polypeptide 6,
                     alpha"
                     /db_xref="GeneID:67371"
                     /db_xref="MGI:MGI:1914621"
     exon            1..134
                     /gene="Gtf3c6"
                     /gene_synonym="2410016F19Rik"
                     /inference="alignment:Splign:2.1.0"
     CDS             54..737
                     /gene="Gtf3c6"
                     /gene_synonym="2410016F19Rik"
                     /note="isoform 2 is encoded by transcript variant 2;
                     general transcription factor 3C polypeptide 6; TFIIIC35;
                     TFIIIC 35 kDa subunit; transcription factor IIIC subunit
                     6; transcription factor IIIC 35 kDa subunit"
                     /codon_start=1
                     /product="general transcription factor 3C polypeptide 6
                     isoform 2"
                     /protein_id="NP_080389.2"
                     /db_xref="CCDS:CCDS23794.1"
                     /db_xref="GeneID:67371"
                     /db_xref="MGI:MGI:1914621"
                     /translation="MASPNAMAAAVDPIWEDLEEEEEELEEEQFVLVELSGIIDSDFL
                     SKCENKCKILGIDTERPIMQVDSYVFAGEYEDTLGTCVIFEEGVERVDPEGTDKTVLK
                     YKCHTMKKLSMTRTLLTEKKEGEENIDGVEWLQMKDNDFSYRPNMICSFLHEHEDEAA
                     GPASDKPVELEDQESQMKGSAEQTQEQEKVEHSEVEDPAPSGETPSEMESSVFMGTQD
                     GNVSQNNQS"
     exon            135..215
                     /gene="Gtf3c6"
                     /gene_synonym="2410016F19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            216..279
                     /gene="Gtf3c6"
                     /gene_synonym="2410016F19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            280..324
                     /gene="Gtf3c6"
                     /gene_synonym="2410016F19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            325..438
                     /gene="Gtf3c6"
                     /gene_synonym="2410016F19Rik"
                     /inference="alignment:Splign:2.1.0"
     exon            439..2569
                     /gene="Gtf3c6"
                     /gene_synonym="2410016F19Rik"
                     /inference="alignment:Splign:2.1.0"
     polyA_site      745
                     /gene="Gtf3c6"
                     /gene_synonym="2410016F19Rik"
                     /note="major polyA site"
     polyA_site      764
                     /gene="Gtf3c6"
                     /gene_synonym="2410016F19Rik"
     regulatory      2548..2553
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gtf3c6"
                     /gene_synonym="2410016F19Rik"
                     /note="hexamer: AATAAA"
     polyA_site      2569
                     /gene="Gtf3c6"
                     /gene_synonym="2410016F19Rik"
ORIGIN      
        1 ccggacgccg ctgcccgtat ccaaaatggc atccacaggg ggcgtggcca gtgatggcgt
       61 ctccgaacgc tatggcggcg gcagtggatc ccatttggga ggacttggag gaggaggaag
      121 aggagctaga ggaggagcag tttgttctgg tagaattgtc aggaatcatt gattcagact
      181 ttctctccaa atgtgaaaat aaatgcaaga ttttgggaat tgacacggag aggcccatca
      241 tgcaagtgga cagctatgtg tttgctgggg agtatgaaga tacgcttggt acctgtgtta
      301 tatttgaaga aggtgttgaa cgagtggatc cagaggggac tgataagacg gtgctgaagt
      361 acaagtgcca cacgatgaag aagctgagca tgacaaggac gcttctgaca gaaaagaagg
      421 aaggagaaga aaacatagat ggcgtagagt ggctgcaaat gaaggataat gatttctcct
      481 atagacccaa catgatttgc agctttctcc atgaacatga agatgaggct gcagggccgg
      541 cctctgataa acctgtggag ctggaagacc aagagagtca gatgaaaggc agtgcggagc
      601 agacacagga gcaggagaag gtggagcact cggaagtgga ggaccctgct ccttcagggg
      661 agaccccttc tgagatggaa agttctgttt tcatgggaac tcaagatgga aatgtttctc
      721 aaaacaacca gtcgtgaact tgaaagaagt ggtcttgtat gcaattactg cttagctgtg
      781 tgtggctcac catcccgtgt tattttgaca gtatgcgttt ccaggtacgt caggacttag
      841 tataccagag tcacgtagga ccacacagga attcagcttt tagaacatga gagagagcat
      901 catagttaaa atgctcttcc agaggacctg gattcgattt ctagtgtata cgtggcagtt
      961 tggagccatc tgagacttca gtttccagag atctgatgcc tgcttctggc ctctgtgagc
     1021 cccaggttct ctccttctac ctttgtggga attaaactca ggtcatcagc cttgtgcagc
     1081 gaacacttta cctgttgggc cgcctcacag ccctctccac acacacccct cctaaaaata
     1141 cttatgtggg gcagttggtg gcacacacct ttgatcccag cactccggaa gcagaagcag
     1201 gcacatttct cagttcaagg gcagccagtc tacaaaatga gtttcaagag agccaagagt
     1261 ttcaaggagg tctgaagaga ctttgggcct cttagaactg gagatagaga tggccatgag
     1321 ccatgtggtg ctgggattgc agtcctgtcc ttcctaagag cagtgagtcc tcctaactgc
     1381 tgggccatca ccactcttgt cttctgcccc atactcaccc tccttttttc ctgagacaga
     1441 gtttttatat gtaacccaga ctagccttaa attctctagc cttctgaccg cagcaagtgt
     1501 tcttgtgttt taaagtcatc ctgtgaagaa tgcaataagt cagatgactt tttttttgta
     1561 caacagatat tatatatctg ggttttgtgg tttttttgtt tgttttgttt aaatcacaga
     1621 tgagttccta gaggatacat attcaatgtc atctaaccta atccagttct gaagttctga
     1681 tccttagtca acctggactt agtgtcagat ccacagcccc ataccatcgt gccatctcta
     1741 gtctacatgc taatctcaag tagttcccca agttacccac cgcctctgac ttgcctacaa
     1801 actgaatgtt cccacaatgc ttttctcacc ttcaattgct tgctagcaca gctcatagaa
     1861 cttgggaaaa ggagtttgtt taccagatgg atttattgct tatttatttt gagacagtgt
     1921 cttaaatagt ccggtcagac ttggacagga gtttgtgcct aggacggtgt atatagttaa
     1981 gtgctatacc actgagactg cccaggtagc tccagccagg cctttaaagc tatttagaag
     2041 ccaccttcct aacttgccat tatccatccc aatatgcaaa aagatggatt tcctggaatg
     2101 gcaggacatg cctttaatct tggtaggcta tgcatttagt tccagtggtc catagggaaa
     2161 ggcagcatct caggttctac accagcacgg tcaacagctc tatgccagca ctggctgcat
     2221 ttcaagatcc tcaccccaaa acagagcaca caaatgcaca gaccttgcaa tggtaaatta
     2281 ggtcacttgt ggtggcaaat gactgtaatt tttgtcactc aagtggcaga aacaacacag
     2341 aattcaagat cccggtgatc tatatagcaa gttacaggcc agagaaagtg atgtagagaa
     2401 accctgtctc aaaacaaaac tcaaaattta ataaagtcag acccaagact gcacactatg
     2461 agattcaatt catactatgt acagcagact aggcaattcc aggcaacacc gtgccactcg
     2521 tggatgggta tgtgagctct ttgaagtaat aaaagtatat tgcatgagaa aaaaaaaa
//
