LOCUS       NP_082177                907 aa            linear   ROD 24-DEC-2024
DEFINITION  general transcription factor 3C polypeptide 2 [Mus musculus].
ACCESSION   NP_082177
VERSION     NP_082177.2
DBSOURCE    REFSEQ: accession NM_027901.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (residues 1 to 907)
  AUTHORS   Bedogni,F. and Hevner,R.F.
  TITLE     Cell-Type-Specific Gene Expression in Developing Mouse Neocortex:
            Intermediate Progenitors Implicated in Axon Development
  JOURNAL   Front Mol Neurosci 14, 686034 (2021)
   PUBMED   34321999
  REMARK    Publication Status: Online-Only
REFERENCE   2  (residues 1 to 907)
  AUTHORS   Rodriguez-de la Rosa,L., Sanchez-Calderon,H., Contreras,J.,
            Murillo-Cuesta,S., Falagan,S., Avendano,C., Dopazo,J.,
            Varela-Nieto,I. and Milo,M.
  TITLE     Comparative gene expression study of the vestibular organ of the
            Igf1 deficient mouse using whole-transcript arrays
  JOURNAL   Hear Res 330 (Pt A), 62-77 (2015)
   PUBMED   26341476
REFERENCE   3  (residues 1 to 907)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   4  (residues 1 to 907)
  AUTHORS   Okazaki,N., Kikuno,R., Ohara,R., Inamoto,S., Koseki,H., Hiraoka,S.,
            Saga,Y., Nagase,T., Ohara,O. and Koga,H.
  TITLE     Prediction of the coding sequences of mouse homologues of KIAA
            gene: III. the complete nucleotide sequences of 500 mouse
            KIAA-homologous cDNAs identified by screening of terminal sequences
            of cDNA clones randomly sampled from size-fractionated libraries
  JOURNAL   DNA Res 10 (4), 167-180 (2003)
   PUBMED   14621295
REFERENCE   5  (residues 1 to 907)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            AK083585.1, AK152439.1 and AK012095.1.
            
            On Jan 28, 2006 this sequence version replaced NP_082177.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK159938.1, AK083585.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164137, SAMN01164138
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..907
                     /organism="Mus musculus"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 17.15 cM"
     Protein         1..907
                     /product="general transcription factor 3C polypeptide 2"
                     /note="TF3C-beta; TFIIIC 110 kDa subunit; transcription
                     factor IIIC subunit beta; transcription factor IIIC 110
                     kDa subunit; TFIIIC-BETA"
                     /calculated_mol_wt=100144
     Region          25..186
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BL74.2)"
     Region          <53..292
                     /region_name="PHA03247"
                     /note="large tegument protein UL36; Provisional"
                     /db_xref="CDD:223021"
     Site            62
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8WUA4; propagated from
                     UniProtKB/Swiss-Prot (Q8BL74.2)"
     Site            130
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8WUA4; propagated from
                     UniProtKB/Swiss-Prot (Q8BL74.2)"
     Site            163
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8WUA4; propagated from
                     UniProtKB/Swiss-Prot (Q8BL74.2)"
     Region          203..289
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BL74.2)"
     Site            219
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8WUA4; propagated from
                     UniProtKB/Swiss-Prot (Q8BL74.2)"
     Site            256
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8WUA4; propagated from
                     UniProtKB/Swiss-Prot (Q8BL74.2)"
     Region          461..517
                     /region_name="WD 1"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BL74.2)"
     Region          548..589
                     /region_name="WD 2"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BL74.2)"
     Region          554..591
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          <555..640
                     /region_name="WD40"
                     /note="WD40 domain, found in a number of eukaryotic
                     proteins that cover a wide variety of functions including
                     adaptor/regulatory modules in signal transduction,
                     pre-mRNA processing and cytoskeleton assembly; typically
                     contains a GH dipeptide 11-24 residues from...; cl29593"
                     /db_xref="CDD:475233"
     Site            593
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8WUA4; propagated from
                     UniProtKB/Swiss-Prot (Q8BL74.2)"
     Region          607..647
                     /region_name="WD 3"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BL74.2)"
     Region          612..652
                     /region_name="WD40 repeat"
                     /note="WD40 repeat [structural motif]"
                     /db_xref="CDD:293791"
     Region          758..780
                     /region_name="Disordered.
                     /evidence=ECO:0000256|SAM:MobiDB-lite"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BL74.2)"
     Region          828..870
                     /region_name="WD 4"
                     /note="propagated from UniProtKB/Swiss-Prot (Q8BL74.2)"
     Site            867
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8WUA4; propagated from
                     UniProtKB/Swiss-Prot (Q8BL74.2)"
     Site            888
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8WUA4; propagated from
                     UniProtKB/Swiss-Prot (Q8BL74.2)"
     Site            891
                     /site_type="phosphorylation"
                     /note="Phosphothreonine.
                     /evidence=ECO:0000250|UniProtKB:Q8WUA4; propagated from
                     UniProtKB/Swiss-Prot (Q8BL74.2)"
     Site            897
                     /site_type="phosphorylation"
                     /note="Phosphoserine.
                     /evidence=ECO:0000250|UniProtKB:Q8WUA4; propagated from
                     UniProtKB/Swiss-Prot (Q8BL74.2)"
     CDS             1..907
                     /gene="Gtf3c2"
                     /gene_synonym="1300004C11Rik; 2610510G03Rik; mKIAA0011;
                     TFIIIC110"
                     /coded_by="NM_027901.2:285..3008"
                     /db_xref="CCDS:CCDS39053.1"
                     /db_xref="GeneID:71752"
                     /db_xref="MGI:MGI:1919002"
ORIGIN      
        1 mdtcgvgyva lgeadpvgsm ivvdspgqee lsqldvkase tsgveasiem slppplpgfe
       61 dssdrrlppd qesltrleqq dlssemskvs ntraskpsgr rggrtargak rpqqrkppst
      121 plvpglldqs nplstpmpkk rsqkskgdll llklskgldq pesphpkrpp edfetpsger
      181 prrraaqval lylqelaeel stalpappls gpkspkvssp tkpkktrqas sqgeedgsar
      241 dedfvlqveg edeeeseaps enssdpepva prstprgpaa gkqkphcrgm apnglpnyim
      301 apvwkclhlt kdlreqhhsf wefaewipva wkwqllsele aapylpqeek splfsvqreg
      361 ipedgtiyri nrfssitahp erwdvsfftg gplwaldwcp vpegsaasqy valfsspdmn
      421 ethplsqlhs gpgllqlwgl gtlqqescpg nrahfvygia cdsgciwdlk fcpsgawehp
      481 etlrkapllp rlgllalacs dgkvllfslp hpeallaqqp pdamkpaiyk vqclatlqvg
      541 svqasdpsec gqclslawmp trphhhlaag yyngmvvfwn lptnsplqri rlsdgslkly
      601 pfqcflahdq avrtiqwcka nshflvsags drkikfwdlr rpyepincik rflstelswl
      661 lpyngvtvaq dncyasyglc gihyidagyl gfkayftapr kgtvwslsgs dwlgtvaagd
      721 isgeliaail pdmasnpinv kkpaerrfpi ykadlipyqd spedqdysst ssetpnppka
      781 rtytetinhh yllfqdtdls sfhnllrrep mlrmqegegh sqlcldrlql eaihkvrfsp
      841 nldsygwlvs ggqsglvrih fvrgltspla hrvqlesran fnamfqpsfp tegpgfspss
      901 hcllpnp
//
