LOCUS       NM_207239               6891 bp    mRNA    linear   ROD 30-APR-2024
DEFINITION  Mus musculus general transcription factor III C 1 (Gtf3c1), mRNA.
ACCESSION   NM_207239 XM_133826
VERSION     NM_207239.1
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 6891)
  AUTHORS   Adams,D.J., Barlas,B., McIntyre,R.E., Salguero,I., van der
            Weyden,L., Barros,A., Vicente,J.R., Karimpour,N., Haider,A.,
            Ranzani,M., Turner,G., Thompson,N.A., Harle,V., Olvera-Leon,R.,
            Robles-Espinoza,C.D., Speak,A.O., Geisler,N., Weninger,W.J.,
            Geyer,S.H., Hewinson,J., Karp,N.A., Fu,B., Yang,F., Kozik,Z.,
            Choudhary,J., Yu,L., van Ruiten,M.S., Rowland,B.D., Lelliott,C.J.,
            Del Castillo Velasco-Herrera,M., Verstraten,R., Bruckner,L.,
            Henssen,A.G., Rooimans,M.A., de Lange,J., Mohun,T.J., Arends,M.J.,
            Kentistou,K.A., Coelho,P.A., Zhao,Y., Zecchini,H., Perry,J.R.B.,
            Jackson,S.P. and Balmus,G.
  CONSRTM   Sanger Mouse Genetics Project
  TITLE     Genetic determinants of micronucleus formation in vivo
  JOURNAL   Nature 627 (8002), 130-136 (2024)
   PUBMED   38355793
REFERENCE   2  (bases 1 to 6891)
  AUTHORS   Sachs,P., Bergmaier,P., Treutwein,K. and Mermoud,J.E.
  TITLE     The Conserved Chromatin Remodeler SMARCAD1 Interacts with TFIIIC
            and Architectural Proteins in Human and Mouse
  JOURNAL   Genes (Basel) 14 (9), 1793 (2023)
   PUBMED   37761933
  REMARK    GeneRIF: The Conserved Chromatin Remodeler SMARCAD1 Interacts with
            TFIIIC and Architectural Proteins in Human and Mouse.
            Publication Status: Online-Only
REFERENCE   3  (bases 1 to 6891)
  AUTHORS   Thompson,C.L., Ng,L., Menon,V., Martinez,S., Lee,C.K.,
            Glattfelder,K., Sunkin,S.M., Henry,A., Lau,C., Dang,C.,
            Garcia-Lopez,R., Martinez-Ferre,A., Pombero,A., Rubenstein,J.L.R.,
            Wakeman,W.B., Hohmann,J., Dee,N., Sodt,A.J., Young,R., Smith,K.,
            Nguyen,T.N., Kidney,J., Kuan,L., Jeromin,A., Kaykas,A., Miller,J.,
            Page,D., Orta,G., Bernard,A., Riley,Z., Smith,S., Wohnoutka,P.,
            Hawrylycz,M.J., Puelles,L. and Jones,A.R.
  TITLE     A high-resolution spatiotemporal atlas of gene expression of the
            developing mouse brain
  JOURNAL   Neuron 83 (2), 309-323 (2014)
   PUBMED   24952961
REFERENCE   4  (bases 1 to 6891)
  AUTHORS   Crepaldi,L., Policarpi,C., Coatti,A., Sherlock,W.T.,
            Jongbloets,B.C., Down,T.A. and Riccio,A.
  TITLE     Binding of TFIIIC to sine elements controls the relocation of
            activity-dependent neuronal genes to transcription factories
  JOURNAL   PLoS Genet 9 (8), e1003699 (2013)
   PUBMED   23966877
REFERENCE   5  (bases 1 to 6891)
  AUTHORS   Wiese,C.B., Ireland,S., Fleming,N.L., Yu,J., Valerius,M.T.,
            Georgas,K., Chiu,H.S., Brennan,J., Armstrong,J., Little,M.H.,
            McMahon,A.P. and Southard-Smith,E.M.
  TITLE     A genome-wide screen to identify transcription factors expressed in
            pelvic Ganglia of the lower urinary tract
  JOURNAL   Front Neurosci 6, 130 (2012)
   PUBMED   22988430
  REMARK    Publication Status: Online-Only
REFERENCE   6  (bases 1 to 6891)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   7  (bases 1 to 6891)
  AUTHORS   de Planell-Saguer,M., Schroeder,D.G., Rodicio,M.C., Cox,G.A. and
            Mourelatos,Z.
  TITLE     Biochemical and genetic evidence for a role of IGHMBP2 in the
            translational machinery
  JOURNAL   Hum Mol Genet 18 (12), 2115-2126 (2009)
   PUBMED   19299493
REFERENCE   8  (bases 1 to 6891)
  AUTHORS   Stryke,D., Kawamoto,M., Huang,C.C., Johns,S.J., King,L.A.,
            Harper,C.A., Meng,E.C., Lee,R.E., Yee,A., L'Italien,L.,
            Chuang,P.T., Young,S.G., Skarnes,W.C., Babbitt,P.C. and Ferrin,T.E.
  TITLE     BayGenomics: a resource of insertional mutations in mouse embryonic
            stem cells
  JOURNAL   Nucleic Acids Res 31 (1), 278-281 (2003)
   PUBMED   12520002
REFERENCE   9  (bases 1 to 6891)
  AUTHORS   Meissner,W., Thomae,R. and Seifart,K.H.
  TITLE     The activity of transcription factor IIIC1 is impaired during
            differentiation of F9 cells
  JOURNAL   J Biol Chem 277 (9), 7148-7156 (2002)
   PUBMED   11741993
  REMARK    GeneRIF: The partial purification of pol III transcription factors
            from PE and EC cells revealed that TFIIIC2 activity could be
            purified from both cell types, whereas TFIIIC1 activity was
            dramatically reduced in extracts from PE cells.
REFERENCE   10 (bases 1 to 6891)
  AUTHORS   Brady,K.P., Rowe,L.B., Her,H., Stevens,T.J., Eppig,J.,
            Sussman,D.J., Sikela,J. and Beier,D.R.
  TITLE     Genetic mapping of 262 loci derived from expressed sequences in a
            murine interspecific cross using single-strand conformational
            polymorphism analysis
  JOURNAL   Genome Res 7 (11), 1085-1093 (1997)
   PUBMED   9371744
COMMENT     PROVISIONAL REFSEQ: This record has not yet been subject to final
            NCBI review. The reference sequence was derived from BC067041.1.
            
            On Aug 30, 2004 this sequence version replaced XM_133826.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: BC067041.1, AK147325.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164139 [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on single protein-coding transcript
            ##RefSeq-Attributes-END##
FEATURES             Location/Qualifiers
     source          1..6891
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="7"
                     /map="7 69.01 cM"
     gene            1..6891
                     /gene="Gtf3c1"
                     /note="general transcription factor III C 1"
                     /db_xref="GeneID:233863"
                     /db_xref="MGI:MGI:107887"
     exon            1..232
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     CDS             12..6317
                     /gene="Gtf3c1"
                     /note="TFIIIC220; TF3C-alpha; TFIIIC 220 kDa subunit;
                     TFIIIC box B-binding subunit; transcription factor IIIC
                     subunit alpha; transcription factor IIIC 220 kDa subunit"
                     /codon_start=1
                     /product="general transcription factor 3C polypeptide 1"
                     /protein_id="NP_997122.1"
                     /db_xref="CCDS:CCDS40122.1"
                     /db_xref="GeneID:233863"
                     /db_xref="MGI:MGI:107887"
                     /translation="MDALESLLDEVALEGLDGLCLPALWSRLESRSPAFPLPLEPYTQ
                     EFLWRALATHPGISFYEEPRERPDLQLQDRYEEIDLETGILESRRDPVTLEDVYPIHM
                     ILENKDGIQGSCRYFKERKDITSSIRSKCLQPRCTMVEAFSRWGKKLIIVASQDMRYR
                     ALIGLEGDPDLKLPDFSYCILERLGRSRWQGELQRDLHTTAFKVDAGKLHYHRKILNK
                     NGLITMQSHVIRLPTGAQQHSILLLLNRFHVDRRSKYDILMEKLSMMLSTRSNQIETL
                     GKLREELGLCERTFKRLYQYMLNAGLAKVVSLPLQEIHPECGPCKTKKGTDVMVRCLK
                     LLKEFKRKMEDDHDDDDDEEVISKGVPPVDIVFERDMLTQTYELIERRGTKGISQAEI
                     RVAMNVGKLEARMLCRLLQRFKVVKGFMEDEGRQRTTKYISCVFAEESDLSRQYAREK
                     ARGELLTTVSLASVQDESLMPEGEEAFLSDSESEEESSCSGGKRRGRGSRGHARASGD
                     AGSGSRPHHSTPAKGGWKVLNLHPLKKPKAAAEERSRRSSACRDGLDTSSSSELNAPF
                     DPHSMDSHSGDIAVIEEVRLDNPKEGGGSQKGGRHGSSQDKPHKTYRLLKRRNLIIEA
                     VTNLRLIESLFTIQKMIMDQEKQEGVSTKCCKKSIIRLVRNLSEEGLLRLYRTTVIQD
                     GIKKKVDLVVHPSMDQNDPLVRSAIEQVRFRISNSSTANRVKVPPAPAPQEEAEEENQ
                     EPEVPSRSANSDPNTSSKPESTRVKKTDEKMGITPLKNYKPVIVPGLGRSIGFLPKMP
                     RLKAMHLFLWYLVYGHPAGHTGEQPALHSERKTGKQESSRPGAQPSSGDDWDTSEAKN
                     NTESSSWESEMELSTEIVYVDEISWMRYVPPIPIHRDFGFGWALVSDILLCLPLSIFV
                     QLVQVSYKVDNLEDFLNDPLKKHTLIRFLPRHIRQQLLYKRRYIFSVVENLQRLCYMG
                     LLQFGPTEKFQDKDQVFVFLKKNAVIVDTTICDPHYNLAHSSRPFERRLYVLDSMQDV
                     ECYWFDLQCICLNTPLGVVRCPCAQKICPDPGSDPEGSLRKEQESAMDKHNLERKCAM
                     LEYTTGSREVVDEGLVPGDGLGAAGLDSSFYAHLKRNWVWTSYIINKARKNNTSENGL
                     TGRLQTFLSKRPMPLGSGGSGRLPLWSEGRADAELCADKEEQFELDREPTPGRNRKVR
                     GGKSQKRKRLKKEPIRKTKRRRRGEHPEAKSKKLRYQDEADQNALRMMTRLRVSWSMQ
                     EDGLLMLCRIASNVLNTKVKGPFVTWQVVRDILHATFEESLDKTSHSVGRRARYIVKN
                     PQAFMNYKVCLAEVYQDKALVGDFMSRKGNYEDPKVCAKEFKEFVEKLKEKFSSGLRN
                     PNLEIPNTLQELFAKYRVLAIGDEKDRVRKEDELNSVEDIHFLVLQNLIQSTLSLSNS
                     QSNSCQSFQIFRLYREFREPVLVRAFMECQKRSLVNRRRVSHSQGPKKNRAVPFVPMS
                     YQLSQSYYKLFTWRFPTTICTESFQFYDRLRTNGMLDQPDHFSFKDLDSSDPSNDLVA
                     FSLDSPGGHCVTALALFSLGLLSVDVRIPEQIVVVDSSMVESEVMKSLGKDGGLDDDE
                     EEEDLDEGSGTKRQGVEVKAHQASHTKYLLMRGYYTVPGMVSTRNLNPNDSIVVNSCQ
                     VKFRLRNTPASTQLGPTGFTATPLEELQAGLSCLPASFTSLVDPQLRTHCPEEFAHQM
                     AQSGYSPEDVAASLEILQAVAAADCFGIDKEKLSRQFSALEKIADRRTRTFLDYIQDL
                     LEQEQVMEVGGNTVRLVTMASAQPWLLHSMRLRDMEVDTKASGDDSQSRLPEGPSIED
                     HTSEGAAVPPVSSHSTKKRPHCPETDAEEATRLPAKKPTLQDVRVAASPRPGAEEQAE
                     AQAPAQLAAPEDADAGGPRQENQENVGVSGLEQLGCEFQLPEGSEDPRGLTESNMAQA
                     AWESGCERVCFVGRPWRGVDGHLNMPVCKGMLEAVLYHIMSRPGVPESCLLQYYQGVL
                     QPVAVLELLRGLESLGCIQKRTLRKPASVSLFSRPVVEGLGQASEAEALSCHESTVTF
                     YEPTLDCTIRLGRVFPHDINWNKWIHL"
     exon            233..442
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            443..619
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            620..763
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            764..860
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            861..984
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            985..1146
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            1147..1262
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            1263..1578
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            1579..1781
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            1782..1918
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            1919..2072
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            2073..2176
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            2177..2361
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            2362..2631
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            2632..2777
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            2778..2875
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            2876..2972
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            2973..3150
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            3151..3289
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            3290..3425
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            3426..3504
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            3505..3693
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            3694..3851
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            3852..3994
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            3995..4076
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            4077..4189
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            4190..4252
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            4253..4346
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            4347..4519
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            4520..4807
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            4808..5067
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            5068..5357
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            5358..5856
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            5857..5896
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            5897..6089
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     exon            6090..6869
                     /gene="Gtf3c1"
                     /inference="alignment:Splign:2.1.0"
     regulatory      6849..6854
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gtf3c1"
                     /note="hexamer: ATTAAA"
     polyA_site      6869
                     /gene="Gtf3c1"
                     /note="major polyA site"
ORIGIN      
        1 ctgaagcggc catggacgcg ctcgagtcgt tgttggacga ggtggccctg gaggggctcg
       61 acggcctgtg cctgcccgcg ctgtggagcc gcctggaatc ccgctcgcct gccttcccat
      121 tgcctctgga accctacacg caggagtttt tgtggcgggc tttagccacg cacccgggca
      181 tcagtttcta cgaggagccg cgagagagac ctgacctgca gctccaagac cggtatgaag
      241 aaatcgactt ggaaactggg attttggagt cgaggaggga cccggtcact ctggaggatg
      301 tctaccccat tcacatgatc ttagagaaca aggatggcat ccagggctcc tgccgatact
      361 ttaaggagag aaaggacatc accagtagca tcaggagcaa gtgtttgcag cctcgatgta
      421 caatggtaga agccttcagc aggtggggta agaagctcat cattgtggct tcccaggaca
      481 tgcggtaccg ggccttgata ggcctagagg gggaccctga tctgaagctt cccgatttct
      541 cctactgcat tctggagcgc ttaggtcgat ccaggtggca aggagagctg cagcgagacc
      601 ttcacaccac cgctttcaag gttgacgctg ggaagcttca ttatcacagg aaaattttga
      661 acaagaatgg gctcattaca atgcagtcac atgtgatccg attacctact ggagcccagc
      721 aacactccat cctcctactc cttaaccggt ttcatgtgga caggaggagc aagtatgaca
      781 tcctcatgga aaagctgtct atgatgctga gcacacggag caaccagatt gagactctgg
      841 gcaagctgag ggaggaactg gggctgtgtg aaaggacatt caagcgtctg taccagtaca
      901 tgctgaatgc tgggctggcc aaggtggtgt cccttccctt gcaggagatt caccctgagt
      961 gtggtccctg taagaccaag aaaggaactg atgtcatggt gcgctgtctt aagctcctga
     1021 aggaattcaa gcgaaagatg gaagacgacc acgatgatga tgacgatgag gaggtcatct
     1081 ccaagggagt ccctcctgtg gacatcgtct ttgagcggga catgctcacg cagacctacg
     1141 agctcattga gcgcagagga acgaaaggaa tttcccaagc tgagatccga gttgctatga
     1201 acgtgggaaa gctggaagca agaatgctgt gtcggctcct tcagaggttc aaggttgtca
     1261 aggggttcat ggaagatgaa ggccggcagc ggaccaccaa gtacatttcc tgtgtgtttg
     1321 cggaggagag tgacttgagc cgacaatatg ctcgtgaaaa ggcccgagga gagctactaa
     1381 ccactgtgag cctcgcctca gtgcaagatg agtccctcat gcctgagggc gaagaggcct
     1441 tcctctctga ctcagaaagt gaggaagaga gcagctgcag tggtggcaag cggaggggcc
     1501 gagggtcccg gggccatgca agagcctcag gggatgctgg gtctggctct cggcctcatc
     1561 actccactcc agccaagggc gggtggaaag tcctaaatct gcacccactg aagaagccga
     1621 aagctgccgc tgaggagagg tcccgcagaa gctccgcttg tagggatggc ctggacacca
     1681 gcagctcgtc tgagctcaat gcccccttcg accctcacag catggacagt cacagtggtg
     1741 acatcgctgt gattgaggag gtccggctcg ataaccccaa ggagggtggt ggctcccaga
     1801 aaggcggacg gcatggctca agccaggaca agcctcacaa aacataccga ctgctaaagc
     1861 gcagaaatct catcatagaa gctgtcacca acctccgcct gattgagagc ctgttcacga
     1921 ttcagaagat gatcatggac caggagaagc aagagggtgt ctccaccaaa tgctgtaaga
     1981 agtccattat ccgcttggtg cggaacctgt ctgaggaggg tctcttgcga ttgtatcgga
     2041 ctacagtcat tcaggatggc atcaagaaga aggtagatct ggtcgtgcac ccatctatgg
     2101 accagaatga tcctcttgtg agaagtgcta ttgagcaggt tcgcttccgg atctccaact
     2161 caagcacagc aaacagagtt aaagttccac cggccccagc gccccaagaa gaagcagaag
     2221 aggaaaacca agaaccagaa gtcccaagtc gatcagcaaa ctctgaccca aacacatcct
     2281 cgaagccaga aagcactcgg gtgaaaaaga ctgacgagaa aatgggcata accccactca
     2341 aaaattataa acctgtcata gttcctggac tcgggcgctc cataggcttc cttcccaaga
     2401 tgccccgcct aaaggcgatg cacctgttcc tgtggtacct ggtgtatggg catcctgccg
     2461 gccacactgg ggagcagcct gctctccaca gtgagaggaa aacgggcaag caggagtcca
     2521 gcagaccagg ggctcagccc tcctcaggag atgactggga cacctctgaa gccaaaaaca
     2581 acacagaaag cagctcctgg gagtcagaaa tggaactctc cacagagata gtgtatgtgg
     2641 atgagatctc atggatgcgc tacgtccctc ccatcccgat ccacagagac tttggctttg
     2701 gctgggctct tgtcagtgac attcttctct gcctgcccct ctccatcttt gtccaacttg
     2761 ttcaagtcag ctacaaggtg gataacctgg aggattttct gaatgacccg ctgaagaagc
     2821 acacactgat ccgcttcctc cccaggcaca tccggcagca gctactgtat aagaggcggt
     2881 atattttctc ggtggtggag aacctgcagc ggctgtgtta catggggctg ctacagtttg
     2941 gacccacaga gaagtttcag gataaagacc aggtctttgt tttcctgaag aagaatgcag
     3001 tcattgtgga caccaccatc tgtgacccac attacaacct ggcccacagc agccggcctt
     3061 ttgagagacg tctctacgtc ctggattcca tgcaggatgt ggaatgctac tggtttgacc
     3121 tgcagtgtat ctgcctaaac accccactag gtgtggtgcg ttgcccgtgt gcacagaaga
     3181 tctgccctga tccaggcagt gacccagaag gcagcttgcg gaaggagcag gagagtgcca
     3241 tggacaagca caacctagag cgcaagtgtg ccatgctgga gtataccacg gggagccgag
     3301 aagttgtgga tgaaggctta gtcccagggg atgggctggg agctgctggg ctggactcca
     3361 gcttctatgc acacttgaag cgcaactggg tctggaccag ctacatcatc aacaaagcca
     3421 gaaagaacaa cacctccgaa aatgggctca caggaagact ccagaccttc ctgtctaagc
     3481 gcccaatgcc ccttgggtcc ggaggcagtg gccgtttgcc tctctggtca gaggggagag
     3541 ctgatgctga gctctgtgct gacaaggaag aacaatttga actggacaga gaacctaccc
     3601 ctggcaggaa ccggaaagtg cgtggtggga agagccagaa gcggaagcgg ctgaagaagg
     3661 agcctataag gaagaccaag cgaagaagaa gaggagagca tccagaagcc aaaagcaaaa
     3721 agctacgcta ccaagatgag gctgaccaga acgccctccg gatgatgacc cggctgcgtg
     3781 tctcttggtc catgcaggag gatgggctgc taatgctctg ccggatcgcc agcaacgtcc
     3841 tcaacaccaa ggtgaaagga ccatttgtca cctggcaggt cgtgcgggac attttgcatg
     3901 ctacctttga agagtctttg gataaaacct ctcactcggt tggacgaaga gctcgctaca
     3961 tagtcaaaaa tccccaggct ttcatgaact acaaggtctg tctggcagaa gtgtaccaag
     4021 ataaggcact tgttggagat ttcatgagtc ggaagggtaa ctacgaagac ccaaaggttt
     4081 gtgccaagga gtttaaagaa tttgtagaga aactgaaaga gaagttcagc tctggcctga
     4141 ggaaccccaa tctcgagatc cccaacacac tgcaggaact ctttgccaag taccgagtgt
     4201 tggcgatcgg ggatgagaag gaccgagtca ggaaggagga tgagctgaat agtgtggagg
     4261 acatccactt cctggtgcta cagaacctga tccagagcac actgtccctc tctaacagcc
     4321 agtccaactc ttgccagtcc ttccagatct tccgcctcta ccgggagttc cgggagcccg
     4381 tgctggtgcg ggccttcatg gagtgccaaa agaggagcct ggtcaaccga cgccgtgtca
     4441 gccactccca gggccccaag aagaaccgtg ccgtgccctt tgtgcccatg tcctaccagc
     4501 tctcccagtc atactacaag cttttcacct ggcgatttcc caccaccatc tgcactgaat
     4561 ccttccagtt ctacgacaga ctgcggacca acggcatgct agaccagcct gatcattttt
     4621 ctttcaagga cctggatagc agtgaccctt caaatgacct ggtggcattt tctttggaca
     4681 gccctggagg acactgtgta acagccctgg ccctcttctc tttggggctc ctctctgtgg
     4741 atgtcagaat cccagagcag atcgtggtgg tggacagctc catggtggag agtgaggtca
     4801 tgaagagctt ggggaaagat ggtggcttgg atgatgacga ggaagaggaa gacctggatg
     4861 aaggttcagg gaccaagcgc cagggtgtgg aagtaaaggc ccatcaggcc tcacacacca
     4921 agtacctgct gatgagaggt tactacacag tgcctggcat ggtcagcaca cgcaacctga
     4981 accccaatga cagcatcgtg gtcaactcct gccaggttaa attccgactg cgcaacaccc
     5041 ctgcatccac ccagcttggg cccactgggt tcacagccac accactggaa gagctccagg
     5101 ctggtctttc ctgcctccct gcctccttta ccagcctggt ggatccacag ctgcgtaccc
     5161 actgcccaga agagtttgcc caccagatgg cacagtcagg gtatagtcct gaggatgtgg
     5221 ctgcctccct agagatcctg caggctgtag cagctgctga ctgcttcggg attgacaagg
     5281 agaagctgag caggcagttc tccgccttgg agaagatagc ggacaggcgc accaggacgt
     5341 tcctggacta catccaggac ctcttggaac aggaacaagt catggaagtt ggaggtaaca
     5401 ctgtgcgcct agtgaccatg gcctctgcac agccctggct tctgcattca atgcgtctga
     5461 gagacatgga agtagacact aaggcctcag gggatgacag ccaatccaga ctccctgagg
     5521 ggccttccat cgaagaccac acctctgagg gagcagcggt gcctccagtc agctcccata
     5581 gcactaaaaa gcgtccccac tgccctgaga ctgatgctga ggaagccaca aggctccctg
     5641 ccaagaagcc cacactacag gatgtccgtg tggctgccag ccctaggcct ggagcggaag
     5701 agcaggcaga ggcccaggcc ccagctcagc ttgcagctcc tgaagatgca gatgcagggg
     5761 gccccagaca ggagaaccaa gagaatgttg gtgtctcagg cctagagcag ctgggctgtg
     5821 agttccagct tccagaaggc tctgaagacc ccagaggcct tacagagagt aacatggccc
     5881 aggcagcgtg ggagagtggc tgtgagagag tgtgtttcgt cggccgccca tggcgaggtg
     5941 tggatgggca cctgaacatg cccgtgtgca aaggcatgct ggaggctgtg ctctaccaca
     6001 tcatgtcaag gcccggcgtt cccgagagct gcctgctgca gtactaccag ggcgtcctgc
     6061 agcctgttgc tgtccttgag ctgctccggg gcctggagtc cctcggctgt atccagaagc
     6121 ggactctgag gaagccagcg agtgtctcgc tcttctccag gcctgtggtg gagggcctgg
     6181 gtcaggccag tgaggctgag gcgctctcct gccacgagag cactgtcacc ttctatgagc
     6241 ccacgctgga ctgtaccatc cgtctgggcc gtgtcttccc ccatgatatc aactggaaca
     6301 agtggatcca tttatagacg ctgccccagg ccagcaggga agcctctgct tcacggctcc
     6361 acctggactg tccatgagcc ctgtcctccc cagctgttcc cacagcgcgg ccccagccca
     6421 gcccagccca gcccaggtgt agcaactagc aggtgacttg agtcccctcc acccgtgctg
     6481 ctcttgctcc caggtgccca gccttcctgc aggcccatgt cctgccctga actcaggctc
     6541 cagcagtggc agcagcaggg tggatgttgt ttggggagca gagctgatga ccaagccctg
     6601 actcacctga aacccaccac accattcaga ctctaggaag ggctttgtga agacacgtca
     6661 caggggtacc tgacagaatc tgctcctctt actctagggc atcccaactt ggcctggact
     6721 gagccccagt ctcccgtggg gacccctcct gccagaagcc aggcctatag gttttgcttt
     6781 tgtttttgtt tcatttttct ctctttccat tagatacagg cccctggcat gtatttattt
     6841 attttgtaat taaagtgaga tgaaatgtaa aaaaaaaaaa aaaaaaaaaa a
//
