LOCUS       NM_001359063            4162 bp    mRNA    linear   ROD 14-JAN-2025
DEFINITION  Mus musculus general transcription factor II I (Gtf2i), transcript
            variant 7, mRNA.
ACCESSION   NM_001359063
VERSION     NM_001359063.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 4162)
  AUTHORS   Bar,E., Fischer,I., Rokach,M., Elad-Sfadia,G., Shirenova,S.,
            Ophir,O., Trangle,S.S., Okun,E. and Barak,B.
  TITLE     Neuronal deletion of Gtf2i results in developmental microglial
            alterations in a mouse model related to Williams syndrome
  JOURNAL   Glia 72 (6), 1117-1135 (2024)
   PUBMED   38450767
  REMARK    GeneRIF: Neuronal deletion of Gtf2i results in developmental
            microglial alterations in a mouse model related to Williams
            syndrome.
REFERENCE   2  (bases 1 to 4162)
  AUTHORS   Nir Sade,A., Levy,G., Schokoroy Trangle,S., Elad Sfadia,G., Bar,E.,
            Ophir,O., Fischer,I., Rokach,M., Atzmon,A., Parnas,H.,
            Rosenberg,T., Marco,A., Elroy Stein,O. and Barak,B.
  TITLE     Neuronal Gtf2i deletion alters mitochondrial and autophagic
            properties
  JOURNAL   Commun Biol 6 (1), 1269 (2023)
   PUBMED   38097729
  REMARK    Publication Status: Online-Only
REFERENCE   3  (bases 1 to 4162)
  AUTHORS   Singh,A., Kaileh,M., De,S., Mazan-Mamczarz,K., Bayarsaihan,D.,
            Sen,R. and Roy,A.L.
  TITLE     Transcription factor TFII-I fine tunes innate properties of B
            lymphocytes
  JOURNAL   Front Immunol 14, 1067459 (2023)
   PUBMED   36756127
  REMARK    GeneRIF: Transcription factor TFII-I fine tunes innate properties
            of B lymphocytes.
            Publication Status: Online-Only
REFERENCE   4  (bases 1 to 4162)
  AUTHORS   Davenport,C.M., Teubner,B.J.W., Han,S.B., Patton,M.H., Eom,T.Y.,
            Garic,D., Lansdell,B.J., Shirinifard,A., Chang,T.C., Klein,J.,
            Pruett-Miller,S.M., Blundon,J.A. and Zakharenko,S.S.
  TITLE     Innate frequency-discrimination hyperacuity in Williams-Beuren
            syndrome mice
  JOURNAL   Cell 185 (21), 3877-3895 (2022)
   PUBMED   36152627
REFERENCE   5  (bases 1 to 4162)
  AUTHORS   Giorgetti,O.B., Nusser,A. and Boehm,T.
  TITLE     Human thymoma-associated mutation of the GTF2I transcription factor
            impairs thymic epithelial progenitor differentiation in mice
  JOURNAL   Commun Biol 5 (1), 1037 (2022)
   PUBMED   36175547
  REMARK    GeneRIF: Human thymoma-associated mutation of the GTF2I
            transcription factor impairs thymic epithelial progenitor
            differentiation in mice.
            Publication Status: Online-Only
REFERENCE   6  (bases 1 to 4162)
  AUTHORS   Bayarsaihan,D., Dunai,J., Greally,J.M., Kawasaki,K., Sumiyama,K.,
            Enkhmandakh,B., Shimizu,N. and Ruddle,F.H.
  TITLE     Genomic organization of the genes Gtf2ird1, Gtf2i, and Ncf1 at the
            mouse chromosome 5 region syntenic to the human chromosome 7q11.23
            Williams syndrome critical region
  JOURNAL   Genomics 79 (1), 137-143 (2002)
   PUBMED   11827466
REFERENCE   7  (bases 1 to 4162)
  AUTHORS   Wang,Y.K., Sporle,R., Paperna,T., Schughart,K. and Francke,U.
  TITLE     Characterization and expression pattern of the frizzled gene Fzd9,
            the mouse homolog of FZD9 which is deleted in Williams-Beuren
            syndrome
  JOURNAL   Genomics 57 (2), 235-248 (1999)
   PUBMED   10198163
REFERENCE   8  (bases 1 to 4162)
  AUTHORS   Paperna,T., Peoples,R., Wang,Y.K., Kaplan,P. and Francke,U.
  TITLE     Genes for the CPE receptor (CPETR1) and the human homolog of RVP1
            (CPETR2) are localized within the Williams-Beuren syndrome deletion
  JOURNAL   Genomics 54 (3), 453-459 (1998)
   PUBMED   9878248
REFERENCE   9  (bases 1 to 4162)
  AUTHORS   Wang,Y.K., Perez-Jurado,L.A. and Francke,U.
  TITLE     A mouse single-copy gene, Gtf2i, the homolog of human GTF2I, that
            is duplicated in the Williams-Beuren syndrome deletion region
  JOURNAL   Genomics 48 (2), 163-170 (1998)
   PUBMED   9521869
REFERENCE   10 (bases 1 to 4162)
  AUTHORS   Yang,W. and Desiderio,S.
  TITLE     BAP-135, a target for Bruton's tyrosine kinase in response to B
            cell receptor engagement
  JOURNAL   Proc Natl Acad Sci U S A 94 (2), 604-609 (1997)
   PUBMED   9012831
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CB250008.1, MG954273.1 and AC093346.7.
            
            Transcript Variant: This variant (7), as well as variants 2 and 8,
            encodes isoform 2.
            
            Sequence Note: This RefSeq record was created from transcript and
            genomic sequence data to make the sequence consistent with the
            reference genome assembly. The genomic coordinates used for the
            transcript record were based on transcript alignments.
            
            Publication Note:  This RefSeq record includes a subset of the
            publications that are available for this gene. Please see the Gene
            record to access additional publications.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AY030291.1 [ECO:0000332]
            RNAseq introns              :: partial sample support SAMN01164131,
                                           SAMN01164137 [ECO:0000350]
            ##Evidence-Data-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-67                CB250008.1         1-67
            68-140              MG954273.1         8-80                c
            141-244             AC093346.7         186957-187060       c
            245-383             AC093346.7         185194-185332       c
            384-518             AC093346.7         180734-180868       c
            519-702             AC093346.7         178307-178490       c
            703-731             AC093346.7         178142-178170       c
            732-786             AC093346.7         174641-174695       c
            787-830             AC093346.7         174234-174277       c
            831-908             AC093346.7         170884-170961       c
            909-965             AC093346.7         165986-166042       c
            966-1028            AC093346.7         163971-164033       c
            1029-1142           AC093346.7         157990-158103       c
            1143-1208           AC093346.7         157184-157249       c
            1209-1392           AC093346.7         155032-155215       c
            1393-1451           AC093346.7         153290-153348       c
            1452-1523           AC093346.7         152014-152085       c
            1524-1707           AC093346.7         147272-147455       c
            1708-1766           AC093346.7         146460-146518       c
            1767-1838           AC093346.7         143313-143384       c
            1839-2022           AC093346.7         141289-141472       c
            2023-2081           AC093346.7         138666-138724       c
            2082-2156           AC093346.7         138268-138342       c
            2157-2258           AC093346.7         137957-138058       c
            2259-2324           AC093346.7         136564-136629       c
            2325-2508           AC093346.7         136141-136324       c
            2509-2564           AC093346.7         135348-135403       c
            2565-2645           AC093346.7         134954-135034       c
            2646-2729           AC093346.7         134355-134438       c
            2730-2913           AC093346.7         134051-134234       c
            2914-2942           AC093346.7         133578-133606       c
            2943-2984           AC093346.7         132320-132361       c
            2985-3026           AC093346.7         131690-131731       c
            3027-3101           AC093346.7         130944-131018       c
            3102-4162           AC093346.7         129279-130339       c
FEATURES             Location/Qualifiers
     source          1..4162
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="5"
                     /map="5 74.48 cM"
     gene            1..4162
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /note="general transcription factor II I"
                     /db_xref="GeneID:14886"
                     /db_xref="MGI:MGI:1202722"
     exon            1..140
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            141..244
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     CDS             146..3085
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /note="isoform 2 is encoded by transcript variant 7;
                     Bruton tyrosine kinase-associated protein 135;
                     BTK-associated protein 135; SRF-Phox1-interacting protein;
                     Williams-Beuren syndrome chromosomal region 6 protein"
                     /codon_start=1
                     /product="general transcription factor II-I isoform 2"
                     /protein_id="NP_001345992.1"
                     /db_xref="CCDS:CCDS39299.1"
                     /db_xref="GeneID:14886"
                     /db_xref="MGI:MGI:1202722"
                     /translation="MAQVVMSALPAEDEESSESRMVVTFLMSALESMCKELAKSKAEV
                     ACIAVYETDVFVVGTERGRAFVNTRKDFQKDFVKYCVEEEEKAAEMHKMKSTTQANRM
                     SVDAVEIETLRKTVEDYFCFCYGKALGKSTVVPVPYEKMLRDQSAVVVQGLPEGVAFK
                     HPEHYDLATLKWILENKAGISFIIKRPFLEPKKHLGGRVLAAEAERSMLSPSGSCGPI
                     KVKTEPTEDSGISLEMAAVTVKEESEDPDYYQYNIQGSHHSSEGNEGTEVEVPAEDST
                     QHVPSETSEDPEVEVTIEDDDYSPPTKRLKSTEPPPPPPVPEPANAGKRKVREFNFEK
                     WNARITDLRKQVEELFERKYAQAIKAKGPVTIPYPLFQSHVEDLYVEGLPEGIPFRRP
                     STYGIPRLERILLAKERIRFVIKKHELLNSTREDLQLDKPASGVKEEWYARITKLRKM
                     VDQLFCKKFAEALGSTEAKAVPYQKFEAHPNDLYVEGLPENIPFRSPSWYGIPRLEKI
                     IQVGNRIKFVIKRPELLTHSTTEVTQPRTNTPVKEDWNVRITKLRKQVEEIFNLKFAQ
                     ALGLTEAVKVPYPVFESNPEFLYVEGLPEGIPFRSPTWFGIPRLERIVRGSNKIKFVV
                     KKPELVVSYLPPGMASKINTKALQSPKRPRSPGSNSKVPEIEVTVEGPNNSSPQTSAV
                     RTPTQTNGSNVPFKPRGREFSFEAWNAKITDLKQKVENLFNEKCGEALGLKQAVKVPF
                     ALFESFPEDFYVEGLPEGVPFRRPSTFGIPRLEKILRNKAKIKFIIKKPEMFETAIKE
                     STSSKSPPRKINSSPNVNTTASGVEDLNIIQVTIPDDDNERLSKVEKARQLREQVNDL
                     FSRKFGEAIGMGFPVKVPYRKITINPGCVVVDGMPPGVSFKAPSYLEISSMRRILDSA
                     EFIKFTVIRPFPGLVINNQLVDQNESEGPVIQESAEASQLEVPVTEEIKETDGSSQIK
                     QEPDPTW"
     exon            245..383
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            384..518
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            519..702
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            703..731
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            732..786
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            787..830
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            831..908
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            909..965
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            966..1028
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            1029..1142
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            1143..1208
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            1209..1392
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            1393..1451
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            1452..1523
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            1524..1707
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            1708..1766
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            1767..1838
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            1839..2022
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            2023..2081
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            2082..2156
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            2157..2258
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            2259..2324
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            2325..2508
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            2509..2564
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            2565..2645
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            2646..2729
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            2730..2913
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            2914..2942
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            2943..2984
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            2985..3026
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            3027..3101
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     exon            3102..4162
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /inference="alignment:Splign:2.1.0"
     regulatory      4129..4134
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /note="hexamer: AATAAA"
     polyA_site      4160
                     /gene="Gtf2i"
                     /gene_synonym="6030441I21Rik; BAP-135; Diws1t; GtfII-I;
                     Spin; TFII-I; WBSCR6"
                     /note="major polyA site"
ORIGIN      
        1 aaaaaaaaaa aggcaaaaaa aaaaaaaggg ggaaaaaaaa ggaggaggag gagggtgaga
       61 gagaagctgg gagagcagag aaaagggggc accggcggcc cccccgcttc cctgcacgcg
      121 cttgccgccc gcctgccgcg gaatcatggc ccaagtagtg atgtctgcct tgcctgccga
      181 agatgaagag tcttcagaga gcaggatggt ggtgaccttc ctcatgtctg ccctggagtc
      241 catgtgtaaa gagctggcca agtccaaggc tgaggtggcc tgcattgctg tgtatgagac
      301 cgacgtgttt gttgttggaa ccgaaagagg gcgtgctttt gtcaatacca gaaaagattt
      361 ccaaaaagac tttgtgaagt attgtgttga agaagaagaa aaggccgccg agatgcataa
      421 gatgaaatct accacccagg ccaatcggat gagtgtggat gctgtagaaa ttgaaacact
      481 cagaaaaacg gtggaggact atttctgttt ttgctatggg aaagctttag gcaaatccac
      541 agtggtccct gtgccatatg agaagatgct gcgcgaccag tcggctgtgg tggtgcaggg
      601 gcttcccgag ggggttgcct tcaagcaccc cgaacattac gacctcgcaa ccttgaagtg
      661 gattttggag aacaaggcag ggatttcctt catcattaag agacctttcc tcgagccgaa
      721 gaaacacctc ggtggtcgag tgctggcggc cgaggctgag aggtccatgc tgtctcctag
      781 tggaagttgt ggccccatca aagtgaaaac tgaacccaca gaagattctg gcatttctct
      841 ggaaatggcc gctgtgacag tgaaggagga gtcagaagac cctgattact atcagtataa
      901 cattcaagga agccatcact cctcagaagg caacgaggga acggaagtgg aagtgccagc
      961 agaagattct actcaacatg tcccttcaga aaccagtgag gaccccgaag ttgaggtgac
     1021 cattgaagat gatgactatt ctccacccac caagaggcta aagagcacgg agccgccccc
     1081 gcccccgccc gtcccggagc ccgccaacgc tggcaagcgc aaagtgaggg agttcaactt
     1141 tgagaaatgg aacgcacgca tcactgacct acggaaacaa gttgaagagt tgttcgaaag
     1201 aaaatatgct caagccatca aagccaaagg cccggtgacg atcccgtacc ctcttttcca
     1261 gtcccatgtt gaagatcttt acgtagaagg gcttcctgaa gggattcctt ttagaaggcc
     1321 gtcgacgtac ggcattcctc gccttgagag gatattgctg gcgaaggaaa ggatccgctt
     1381 cgtgattaag aaacatgagc ttctgaactc aacacgagaa gatttacagc ttgataaacc
     1441 agcctcagga gtgaaagaag agtggtacgc tcgcatcacc aaactgagga agatggttga
     1501 ccagctcttc tgcaagaaat ttgccgaggc cttgggaagc acggaagcca aggctgtacc
     1561 gtaccaaaaa tttgaggccc atcccaatga tctctatgtg gaaggacttc cagaaaacat
     1621 tcctttccga agcccctcgt ggtatggaat cccaagactg gaaaaaatca tccaagtggg
     1681 caatcgaatt aaatttgtta tcaagagacc agagctgctc actcacagca caactgaagt
     1741 gactcagcca cggacaaaca caccagtcaa agaagattgg aatgtcagaa tcaccaagct
     1801 ccgaaagcaa gtggaagaga tctttaattt gaagtttgct caggctctgg gcctcacaga
     1861 ggctgtgaag gtgccatatc ctgtgttcga atccaacccg gagtttctgt atgtggaagg
     1921 gctccccgaa gggatcccct tccgaagccc tacctggttt gggattccac gcctcgagag
     1981 gattgtccgt ggcagcaata agatcaagtt tgttgttaaa aagcctgagc tagttgtgtc
     2041 ctatttgcct cctgggatgg ctagcaaaat caacactaaa gcattgcagt ccccaaaacg
     2101 accacgaagc cctgggagca actccaaggt tcctgaaatt gaggtcactg tggaaggccc
     2161 caacaacagc agtcctcaga cctctgcggt tcgaactcct acccagacca atggttcaaa
     2221 tgttcccttc aagcctcgag ggagagagtt ttcctttgag gcctggaatg ctaagatcac
     2281 agacctgaag cagaaagtgg agaacctctt caatgaaaag tgcggggaag cgcttggcct
     2341 taagcaggct gtgaaagtcc cgtttgcgtt gttcgagtcc ttcccagaag acttctatgt
     2401 ggaaggcttg cccgaggggg tgcccttccg aaggccgtcc acatttggca ttcccaggct
     2461 ggagaagata ctccggaaca aggccaagat aaagttcatc attaaaaaac ctgagatgtt
     2521 cgagacggcc atcaaagaga gcacctcttc caaaagccct ccaagaaaga taaactcatc
     2581 acccaacgtt aatactactg catcaggtgt ggaagacctg aacatcatcc aggtgacaat
     2641 tccagatgac gataatgaac gactgtccaa agttgaaaag gccaggcagc tgcgggagca
     2701 ggtcaacgac ctcttcagtc ggaagtttgg tgaagctatt gggatgggct tcccggtgaa
     2761 ggtcccctac aggaagatca ccatcaaccc tggctgcgtg gtggtcgatg gcatgccccc
     2821 cggggtgtcc ttcaaagccc ccagttacct ggagatcagc tccatgagga ggatcttaga
     2881 ctctgcggag tttatcaagt tcactgtcat tagaccattt ccaggacttg tgattaataa
     2941 ccagctggtt gatcagaacg agtctgaagg ccctgtgata caagaatcag ccgaggcaag
     3001 ccagttggaa gtcccagtaa cagaagaaat taaagagaca gatgggagtt cacagatcaa
     3061 gcaggagcca gaccccacgt ggtagaccgt ggctctccag gttcgtccag tgtccagcgt
     3121 gcgtggtgga gaagagcttt gggacccgtt cctgccagct ctgtaatata cttgtataac
     3181 agaaatacct tctatacaaa ccttcttttc tacttttaga tagaaatgtc tactttctca
     3241 gcagttctgt gaattgagct acacagcgtg atgagatgcg cgtgcctggt ggcttgggaa
     3301 cgcactagaa gggtcttgca gcagtgctga aagaggcggg aatggcaggg acgactcgta
     3361 gggtttctta tgcatcgggc agagccttgg gctgtggtgc gtgttcccgt cagtgagata
     3421 ttcctacagg gcatcttggc ttccgcagca aaggaagtcc ctgtgctagt cagtgcttta
     3481 gtttttctat tgaagaccag ttccgtggtc ttgcactcgg ctgcccctcc tgccagggga
     3541 gggctgctgt ctgtgtgtgt gactaagcct cttcccaagc tccatcacga ttcctttgtc
     3601 ctcactgcca ttcagagcaa agccggccag ctcgcctgac cgccagtgag cagccagtgc
     3661 atccgtgcag tgcagctgga gaggctagcc tcagagcctc gctccggtta ctttacagca
     3721 agtagatttc tgggtgtgtc ctaaaggtca gaggtcaggt ctgcatgctt gagcaggtgg
     3781 aggatttgcc cctccccaac tgggacccac agtggcctca ggggctctgg gccgcagctc
     3841 tgggtctggg tcgagtcagg ctgggctgtg tgtctgcctg gttggttagt ctctaaccac
     3901 ctgtctggcc tctgcgccag ggtggggagt gaggacattg gtgtcccgcc ctatgtgggg
     3961 gctcacagac gatgataagg taacagctct cagcagttag gcacgtgagg gcacggttct
     4021 cggtagtcac cacaatgttc acaatgggaa attatatcac acggtagcag agataggcat
     4081 tttatgtgtt ccttatattt tacctcaaat tgtagatata gggtaataaa taaaatccat
     4141 ccatgccttt cacatgcaaa ct
//
