LOCUS       NM_001419472            1822 bp    mRNA    linear   ROD 14-JUN-2024
DEFINITION  Mus musculus general transcription factor IIF, polypeptide 1
            (Gtf2f1), transcript variant 13, mRNA.
ACCESSION   NM_001419472 XM_006525194
VERSION     NM_001419472.1
KEYWORDS    RefSeq.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1822)
  AUTHORS   Kamileri,I., Karakasilioti,I., Sideri,A., Kosteas,T., Tatarakis,A.,
            Talianidis,I. and Garinis,G.A.
  TITLE     Defective transcription initiation causes postnatal growth failure
            in a mouse model of nucleotide excision repair (NER) progeria
  JOURNAL   Proc Natl Acad Sci U S A 109 (8), 2995-3000 (2012)
   PUBMED   22323595
REFERENCE   2  (bases 1 to 1822)
  AUTHORS   Wagner,S.D., Kugel,J.F. and Goodrich,J.A.
  TITLE     TFIIF facilitates dissociation of RNA polymerase II from noncoding
            RNAs that lack a repression domain
  JOURNAL   Mol Cell Biol 30 (1), 91-97 (2010)
   PUBMED   19841064
REFERENCE   3  (bases 1 to 1822)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   4  (bases 1 to 1822)
  AUTHORS   Combes,A.N., Lesieur,E., Harley,V.R., Sinclair,A.H., Little,M.H.,
            Wilhelm,D. and Koopman,P.
  TITLE     Three-dimensional visualization of testis cord morphogenesis, a
            novel tubulogenic mechanism in development
  JOURNAL   Dev Dyn 238 (5), 1033-1041 (2009)
   PUBMED   19334288
REFERENCE   5  (bases 1 to 1822)
  AUTHORS   Newberry,E.P., Latifi,T., Battaile,J.T. and Towler,D.A.
  TITLE     Structure-function analysis of Msx2-mediated transcriptional
            suppression
  JOURNAL   Biochemistry 36 (34), 10451-10462 (1997)
   PUBMED   9265625
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            CT571247.13 and AC073683.3.
            
            On Apr 3, 2023 this sequence version replaced XM_006525194.5.
            
            ##Evidence-Data-START##
            Transcript exon combination :: SRR17253013.3363127.1,
                                           SRR7345562.3447482.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN01164143 [ECO:0000348]
            ##Evidence-Data-END##
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-290               CT571247.13        29475-29764         c
            291-329             CT571247.13        29342-29380         c
            330-402             CT571247.13        28054-28126         c
            403-477             CT571247.13        26198-26272         c
            478-596             AC073683.3         1-119
            597-767             AC073683.3         676-846
            768-952             AC073683.3         2288-2472
            953-1106            AC073683.3         3013-3166
            1107-1168           AC073683.3         3260-3321
            1169-1288           AC073683.3         3404-3523
            1289-1362           AC073683.3         3637-3710
            1363-1501           AC073683.3         3779-3917
            1502-1592           AC073683.3         4021-4111
            1593-1822           AC073683.3         4201-4430
FEATURES             Location/Qualifiers
     source          1..1822
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 29.62 cM"
     gene            1..1822
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /note="general transcription factor IIF, polypeptide 1"
                     /db_xref="GeneID:98053"
                     /db_xref="MGI:MGI:1923848"
     exon            1..290
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     exon            291..329
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     exon            330..402
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     CDS             355..1797
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /note="isoform 12 is encoded by transcript variant 13;
                     general transcription factor IIF subunit 1; general
                     transcription factor IIF polypeptide 1 (74kD subunit);
                     TFIIF-alpha; transcription initiation factor IIF subunit
                     alpha"
                     /codon_start=1
                     /product="general transcription factor IIF subunit 1
                     isoform 12"
                     /protein_id="NP_001406401.1"
                     /db_xref="GeneID:98053"
                     /db_xref="MGI:MGI:1923848"
                     /translation="MAFNAADKVNFATWNQARLERDLSNKKIYQEEEMPESGAGSEFN
                     RKLREEARRKKYGIVLKEFRPEDQPWLLRVNGKSGRKFKGIKKGGVTENTAYYIFTQC
                     ADGAFEAFPVQNWYNFTPLARHRTLTAEEAEEEWERRNKVLNHFSIMQQRRLKDQDQD
                     EDEEEKEKRSRKKPSELRIHDLEDDLEMSSDASDASGEEGSRTSKAKKKAPVTKAGRK
                     KKKKKGSDDEAFEDSDDGDFEGQEVDYMSDGSSSSPDETEGKPKVPQQEDGPKGVDEQ
                     SESSEESEEEKPPEEDKEEEEEKKAPTPQEKKRRKDSSDDSDSSEESDIDSETSSALF
                     MAKKKTPPKRERKPSGGSSKGTSRPGTPSAEAASTSSTLRAAASKLEQGKRTSETPAA
                     KRLRMDTGPQSLSGKSTPSSGDVQVTEDAVRRYLTRKPMTTKDLLKKFQTKKTGLSSE
                     QTVNVLAQILKRLNPERKMIGDKMHFSLKE"
     exon            403..596
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     exon            597..767
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     exon            768..952
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     exon            953..1106
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     exon            1107..1168
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     exon            1169..1288
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     exon            1289..1362
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     exon            1363..1501
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     exon            1502..1592
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     exon            1593..1822
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /inference="alignment:Splign:2.1.0"
     regulatory      1802..1807
                     /regulatory_class="polyA_signal_sequence"
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /note="hexamer: AATAAA"
     polyA_site      1822
                     /gene="Gtf2f1"
                     /gene_synonym="2810405L04Rik; RAP74"
                     /note="major polyA site"
ORIGIN      
        1 ggctttctct ccgaagctgg tgatctagag tagttacagc ggctgcgctc ttctcggtgt
       61 ggcagctcaa cttccgggtc aggctctaac gcatgcgcag agagttaggt ctctttttct
      121 cgtcttccag cattctccga gacttaagga tttggaaatc caaagcacag catcacacta
      181 acgtgacaac caggaaaggt gccttccctt tcctggagcc gagggacaca acgaagttca
      241 tcccgtcagg ccgaccggga gcagcttgag caacggccat ggcggctcta cagccagaat
      301 gtcaccgagt acgtcgtccg agtccccaag aacacagcca aaagatacaa cataatggct
      361 tttaatgcag ccgataaagt caactttgct acctggaacc aggcacggct ggagcgagat
      421 ctgagcaaca agaagattta ccaggaagaa gagatgccag agtccggtgc aggcagtgaa
      481 ttcaaccgca agcttaggga ggaggcgcgc cggaagaagt atggcattgt cctaaaggag
      541 tttcggcctg aggaccagcc ttggctactc cgtgtcaatg gcaaatcagg acggaagttc
      601 aaaggcatta agaaaggcgg ggtaacagag aacacagcct actacatctt cacacagtgt
      661 gctgatggtg cctttgaggc tttccctgta cagaactggt acaatttcac accactggcc
      721 cgacaccgca cactcactgc tgaggaagcc gaggaggaat gggagaggag gaacaaggtc
      781 ctaaaccact tcagcatcat gcagcagcgg cggctcaagg accaggacca ggatgaagat
      841 gaggaggaga aggagaagcg cagtcgcaag aagcctagtg agctgcgcat tcatgacctg
      901 gaggatgacc tggaaatgtc ctccgatgcc agcgatgcca gtggtgaaga gggcagcaga
      961 acctccaagg ctaagaaaaa ggcccctgtg accaaggcag gcaggaagaa gaaaaagaag
     1021 aagggctcag atgatgaggc ttttgaggac agcgatgatg gggacttcga gggccaggag
     1081 gtagactaca tgtctgatgg ctccagcagc tctccagatg agacagaagg caagcccaaa
     1141 gtgccccagc aggaggatgg cccaaagggg gtggatgagc agagcgagag cagtgaggag
     1201 agtgaggagg agaagccccc cgaggaggac aaggaggagg aagaagagaa gaaggcccct
     1261 accccacaag agaagaagcg caggaaagac agcagtgatg actcagacag ctcagaagag
     1321 agcgacattg acagtgagac ctcctctgca ctcttcatgg cgaagaagaa gacaccccca
     1381 aagagggagc ggaagccatc gggggggagt tcaaagggca ccagtcggcc agggactccc
     1441 agtgcagaag cagcaagcac ctcttctacc ctgcgggctg cagccagcaa gctggagcag
     1501 gggaagcgga cgagtgagac tccagcagcc aagcgtcttc ggatggacac gggtccccag
     1561 agcctgtctg ggaagtccac acccagcagc ggtgatgtcc aggtgacaga ggacgctgtg
     1621 cgccgctacc tgacccgcaa gcccatgacc acaaaggacc tgctgaagaa gttccagacc
     1681 aagaagacag ggctgagcag cgagcagaca gtaaatgtgc tggcgcagat cctcaagcgc
     1741 ctcaaccctg agcgcaagat gattggtgat aagatgcact tctccctcaa agagtgatgc
     1801 caataaagag agcaggccca ga
//
