LOCUS       NM_023630               1619 bp    mRNA    linear   ROD 03-JUN-2024
DEFINITION  Mus musculus general transcription factor IIA, 1-like (Gtf2a1l),
            mRNA.
ACCESSION   NM_023630
VERSION     NM_023630.2
KEYWORDS    RefSeq; RefSeq Select.
SOURCE      Mus musculus (house mouse)
  ORGANISM  Mus musculus
            Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi;
            Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha;
            Muroidea; Muridae; Murinae; Mus; Mus.
REFERENCE   1  (bases 1 to 1619)
  AUTHORS   Yu,C., Cvetesic,N., Hisler,V., Gupta,K., Ye,T., Gazdag,E.,
            Negroni,L., Hajkova,P., Berger,I., Lenhard,B., Muller,F.,
            Vincent,S.D. and Tora,L.
  TITLE     TBPL2/TFIIA complex establishes the maternal transcriptome through
            oocyte-specific promoter usage
  JOURNAL   Nat Commun 11 (1), 6439 (2020)
   PUBMED   33353944
  REMARK    GeneRIF: TBPL2/TFIIA complex establishes the maternal transcriptome
            through oocyte-specific promoter usage.
            Publication Status: Online-Only
REFERENCE   2  (bases 1 to 1619)
  AUTHORS   Shawlot,W., Vazquez-Chantada,M., Wallingford,J.B. and Finnell,R.H.
  TITLE     Rfx2 is required for spermatogenesis in the mouse
  JOURNAL   Genesis 53 (9), 604-611 (2015)
   PUBMED   26248850
REFERENCE   3  (bases 1 to 1619)
  AUTHORS   Oyama,T., Sasagawa,S., Takeda,S., Hess,R.A., Lieberman,P.M.,
            Cheng,E.H. and Hsieh,J.J.
  TITLE     Cleavage of TFIIA by Taspase1 activates TRF2-specified mammalian
            male germ cell programs
  JOURNAL   Dev Cell 27 (2), 188-200 (2013)
   PUBMED   24176642
  REMARK    GeneRIF: Taspase1 cleaves a ubiquitously expressed GTF (TFIIA) to
            enable tissue-specific (testis) transcription, meeting the demand
            for sophisticated regulation of distinct subsets of genes in higher
            organisms.
REFERENCE   4  (bases 1 to 1619)
  AUTHORS   Yokoyama,S., Ito,Y., Ueno-Kudoh,H., Shimizu,H., Uchibe,K.,
            Albini,S., Mitsuoka,K., Miyaki,S., Kiso,M., Nagai,A., Hikata,T.,
            Osada,T., Fukuda,N., Yamashita,S., Harada,D., Mezzano,V., Kasai,M.,
            Puri,P.L., Hayashizaki,Y., Okado,H., Hashimoto,M. and Asahara,H.
  TITLE     A systems approach reveals that the myogenesis genome network is
            regulated by the transcriptional repressor RP58
  JOURNAL   Dev Cell 17 (6), 836-848 (2009)
   PUBMED   20059953
REFERENCE   5  (bases 1 to 1619)
  AUTHORS   Xiao,L., Kim,M. and DeJong,J.
  TITLE     Developmental and cell type-specific regulation of core promoter
            transcription factors in germ cells of frogs and mice
  JOURNAL   Gene Expr Patterns 6 (4), 409-419 (2006)
   PUBMED   16412700
REFERENCE   6  (bases 1 to 1619)
  AUTHORS   Catena,R., Argentini,M., Martianov,I., Parello,C., Brancorsini,S.,
            Parvinen,M., Sassone-Corsi,P. and Davidson,I.
  TITLE     Proteolytic cleavage of ALF into alpha- and beta-subunits that form
            homologous and heterologous complexes with somatic TFIIA and TRF2
            in male germ cells
  JOURNAL   FEBS Lett 579 (16), 3401-3410 (2005)
   PUBMED   15927180
  REMARK    GeneRIF: Endogenous ALF is proteolytically cleaved to give alpha-
            and beta-subunits and its cleavage site was mapped.
REFERENCE   7  (bases 1 to 1619)
  AUTHORS   Han,S., Xie,W., Kim,S.H., Yue,L. and DeJong,J.
  TITLE     A short core promoter drives expression of the ALF transcription
            factor in reproductive tissues of male and female mice
  JOURNAL   Biol Reprod 71 (3), 933-941 (2004)
   PUBMED   15151936
  REMARK    GeneRIF: unique core promoter that is active in both male and
            female reproductive tissue suggesting ALF may have a regulatory
            role in male and female gametogenic gene expression programs.
REFERENCE   8  (bases 1 to 1619)
  AUTHORS   Upadhyaya,A.B., Khan,M., Mou,T.C., Junker,M., Gray,D.M. and
            DeJong,J.
  TITLE     The germ cell-specific transcription factor ALF. Structural
            properties and stabilization of the TATA-binding protein (TBP)-DNA
            complex
  JOURNAL   J Biol Chem 277 (37), 34208-34216 (2002)
   PUBMED   12107178
  REMARK    GeneRIF: a role for ALF in the assembly and stabilization of
            initiation complexes in germ cells is likely to be similar or
            identical to the role of TFIIA in somatic cells.
REFERENCE   9  (bases 1 to 1619)
  AUTHORS   Xie,W., Han,S., Khan,M. and DeJong,J.
  TITLE     Regulation of ALF gene expression in somatic and male germ line
            tissues involves partial and site-specific patterns of methylation
  JOURNAL   J Biol Chem 277 (20), 17765-17774 (2002)
   PUBMED   11889132
REFERENCE   10 (bases 1 to 1619)
  AUTHORS   Han,S.Y., Zhou,L., Upadhyaya,A., Lee,S.H., Parker,K.L. and
            DeJong,J.
  TITLE     TFIIAalpha/beta-like factor is encoded by a germ cell-specific gene
            whose expression is up-regulated with other general transcription
            factors during spermatogenesis in the mouse
  JOURNAL   Biol Reprod 64 (2), 507-517 (2001)
   PUBMED   11159353
COMMENT     VALIDATED REFSEQ: This record has undergone validation or
            preliminary review. The reference sequence was derived from
            BY092414.1 and AK005881.1.
            
            On Jul 30, 2009 this sequence version replaced NM_023630.1.
            
            ##Evidence-Data-START##
            Transcript exon combination :: AK005881.1, BC050756.1 [ECO:0000332]
            RNAseq introns              :: single sample supports all introns
                                           SAMN00849384, SAMN01164139
                                           [ECO:0000348]
            ##Evidence-Data-END##
            
            ##RefSeq-Attributes-START##
            RefSeq Select criteria :: based on conservation, expression,
                                      longest protein
            ##RefSeq-Attributes-END##
            COMPLETENESS: complete on the 3' end.
PRIMARY     REFSEQ_SPAN         PRIMARY_IDENTIFIER PRIMARY_SPAN        COMP
            1-25                BY092414.1         1-25
            26-1619             AK005881.1         1-1594
FEATURES             Location/Qualifiers
     source          1..1619
                     /organism="Mus musculus"
                     /mol_type="mRNA"
                     /strain="C57BL/6"
                     /db_xref="taxon:10090"
                     /chromosome="17"
                     /map="17 58.22 cM"
     gene            1..1619
                     /gene="Gtf2a1l"
                     /gene_synonym="1700011N16Rik; Alf; Gtf2a1lf"
                     /note="general transcription factor IIA, 1-like"
                     /db_xref="GeneID:71828"
                     /db_xref="MGI:MGI:1919078"
     exon            1..72
                     /gene="Gtf2a1l"
                     /gene_synonym="1700011N16Rik; Alf; Gtf2a1lf"
                     /inference="alignment:Splign:2.1.0"
     CDS             52..1458
                     /gene="Gtf2a1l"
                     /gene_synonym="1700011N16Rik; Alf; Gtf2a1lf"
                     /note="general transcription factor IIA, 1-like factor;
                     general transcription factor II A, 1-like factor;
                     TfIIa-alpha/beta-like factor"
                     /codon_start=1
                     /product="TFIIA-alpha and beta-like factor"
                     /protein_id="NP_076119.2"
                     /db_xref="CCDS:CCDS29024.1"
                     /db_xref="GeneID:71828"
                     /db_xref="MGI:MGI:1919078"
                     /translation="MAFINLVPKLYQSVIEDVIEGVRDLFAEEGIEEQVLKDLKKLWE
                     TKVLQSKATEDFFRNSTQVPLLTLQLPHALPPALQPEASLLIPAGRTLPSFTPEDLNT
                     ANCGANFAFAGYPIHVPAGMAFQTASGHLYKVNVPVMVTQTSGRTEILQHPFQQVLQQ
                     LGQPLVIQTTVPTLHPCSLQAATEKSLRMEAVLQPPPILHPPPVDRTHVENAASDRRL
                     LPGNELRPQESSPYLSLPGVGFPPQAALTESSLEPVLGVSASLTQNLHSDPFSQGPPG
                     PLHHHLLESQLQSLKDSIYGCDSTKQLRKAEEPSSLRVSEKNCTSERDLNIRVTDDDI
                     NEIIQIDGTGDNSSTEEMGSIRDADENEFPGIIDAGDLNVLEEVDSVSNEDSTANSSD
                     NEDHQINAPEEDPLNSGDDVSEQDVPDLFDTENVIVCQYDKIHRSKNRWKFYLKDGVM
                     CFGGRDYVFAKAIGEAEW"
     exon            73..174
                     /gene="Gtf2a1l"
                     /gene_synonym="1700011N16Rik; Alf; Gtf2a1lf"
                     /inference="alignment:Splign:2.1.0"
     exon            175..295
                     /gene="Gtf2a1l"
                     /gene_synonym="1700011N16Rik; Alf; Gtf2a1lf"
                     /inference="alignment:Splign:2.1.0"
     exon            296..351
                     /gene="Gtf2a1l"
                     /gene_synonym="1700011N16Rik; Alf; Gtf2a1lf"
                     /inference="alignment:Splign:2.1.0"
     exon            352..436
                     /gene="Gtf2a1l"
                     /gene_synonym="1700011N16Rik; Alf; Gtf2a1lf"
                     /inference="alignment:Splign:2.1.0"
     exon            437..1002
                     /gene="Gtf2a1l"
                     /gene_synonym="1700011N16Rik; Alf; Gtf2a1lf"
                     /inference="alignment:Splign:2.1.0"
     exon            1003..1260
                     /gene="Gtf2a1l"
                     /gene_synonym="1700011N16Rik; Alf; Gtf2a1lf"
                     /inference="alignment:Splign:2.1.0"
     exon            1261..1350
                     /gene="Gtf2a1l"
                     /gene_synonym="1700011N16Rik; Alf; Gtf2a1lf"
                     /inference="alignment:Splign:2.1.0"
     exon            1351..1619
                     /gene="Gtf2a1l"
                     /gene_synonym="1700011N16Rik; Alf; Gtf2a1lf"
                     /inference="alignment:Splign:2.1.0"
ORIGIN      
        1 tggcggctct ctgccacgca ggcgcaaacg gttaggcaca gagcggctgg catggccttc
       61 atcaacctgg tgcccaaact ctaccagtct gtaattgaag atgtcatcga gggcgtgcgg
      121 gacctgtttg ctgaggaagg catcgaggag caggtgttga aagacctgaa gaagctctgg
      181 gaaaccaaag tgttacaatc taaagccaca gaggacttct tcagaaacag cacgcaggtg
      241 cctcttctca ctctccagct gcctcatgcc ttaccaccag ccctgcagcc cgaagcatcg
      301 ctgctgatcc cagctggtag aactctgccg agttttacgc cggaagacct gaacaccgcc
      361 aactgtggtg caaactttgc ctttgctggc tatccgatcc acgtcccagc aggcatggcc
      421 ttccagacgg catctggtca cctttacaaa gtcaatgtac cagtcatggt gacacagact
      481 tctgggagaa cagaaattct ccagcatcca tttcagcaag tccttcagca gctcgggcag
      541 cctttagtaa tacagaccac tgttccaaca ttgcacccat gttctcttca agcagcaact
      601 gagaaatccc tcagaatgga agctgtgctg cagccacctc ccattctgca tcctcctcca
      661 gtggacagga cacatgtaga aaatgctgcg agcgacaggc gccttctccc gggaaatgag
      721 ctgaggccgc aggaaagctc tccatacctc agccttcccg gtgtgggctt tcctcctcag
      781 gccgctctga cagagtctag cctggagcca gtgcttggtg tctcagcgag cctgactcag
      841 aatctgcaca gtgacccttt ctcacagggc cccccaggcc ctctccacca ccacttgcta
      901 gagtcacagc ttcaaagcct taaagacagt atatatggat gcgactccac aaagcaactg
      961 agaaaagcag aggagcccag cagcctccgt gtgtcagaga agaattgtac ttcagagagg
     1021 gatctgaata ttcgggtaac cgatgatgat attaatgaaa taatccaaat agatggaacc
     1081 ggcgataact cttctactga agagatggga agtataaggg atgcagatga gaatgaattc
     1141 ccagggatca ttgatgccgg cgacctcaat gtgcttgaag aagtggacag cgtatcgaat
     1201 gaagattcaa ctgcaaatag cagcgacaac gaggaccatc aaataaatgc cccagaagag
     1261 gatcccctaa attctggcga tgatgtcagt gagcaggatg tgccagacct gtttgataca
     1321 gagaatgtaa ttgtctgtca gtatgataag atccaccgga gcaagaacag atggaaattc
     1381 tacttgaaag atggtgtcat gtgctttgga gggagagact acgtatttgc caaagccatt
     1441 ggtgaagctg agtggtaacc tcccgaggct cggtgcgtcc gtcagcgctg tgagcctgtg
     1501 tgggactggc tactgtattg tatgtgtggc ccacattctt attttacatg tgctccatca
     1561 aagaattgat taactttttg ttcactatat ggaattaaat aaaagtatag ttcaaatgc
//
